Michelle C Mendoza

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex
    Michelle C Mendoza
    Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 41:661-71. 2011
  2. pmc Phosphoregulation of the WAVE regulatory complex and signal integration
    Michelle C Mendoza
    Department of Cell Biology, Harvard Medical School, Boston, MA 02115, United States
    Semin Cell Dev Biol 24:272-9. 2013
  3. doi request reprint ERK-MAP Kinase signaling in the cytoplasm
    Michelle C Mendoza
    Department of Cell Biology, Harvard Medical School, Boston, MA, USA
    Methods Mol Biol 661:185-203. 2010
  4. doi request reprint AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve
    Ekrem Emrah Er
    Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
    Sci Signal 6:ra45. 2013
  5. pmc Quantitative fluorescent speckle microscopy (QFSM) to measure actin dynamics
    Michelle C Mendoza
    Department of Cell Biology, Harvard Medical School, Boston, MA, USA
    Curr Protoc Cytom . 2012
  6. pmc The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
    Michelle C Mendoza
    Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
    Trends Biochem Sci 36:320-8. 2011
  7. pmc p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling
    Yuki Abe
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 284:14939-48. 2009

Collaborators

Detail Information

Publications7

  1. pmc ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex
    Michelle C Mendoza
    Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 41:661-71. 2011
    ..Thus, ERK coordinates adhesion disassembly with WRC activation and actin polymerization to promote productive leading edge advancement during cell migration...
  2. pmc Phosphoregulation of the WAVE regulatory complex and signal integration
    Michelle C Mendoza
    Department of Cell Biology, Harvard Medical School, Boston, MA 02115, United States
    Semin Cell Dev Biol 24:272-9. 2013
    ..The combination of WRC phosphorylation events and WRC activity is controlled by stimulus, cell type, and cell cycle-specific pathway activation and via pathway cross-inhibition and cross-activation...
  3. doi request reprint ERK-MAP Kinase signaling in the cytoplasm
    Michelle C Mendoza
    Department of Cell Biology, Harvard Medical School, Boston, MA, USA
    Methods Mol Biol 661:185-203. 2010
    ..The level of ERK phosphotransferase activity, or (32)P-labeled phosphate transfer, is quantitated using a PhosphorImager...
  4. doi request reprint AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve
    Ekrem Emrah Er
    Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
    Sci Signal 6:ra45. 2013
    ....
  5. pmc Quantitative fluorescent speckle microscopy (QFSM) to measure actin dynamics
    Michelle C Mendoza
    Department of Cell Biology, Harvard Medical School, Boston, MA, USA
    Curr Protoc Cytom . 2012
    ..QFSM software identifies and computationally tracks and utilizes the location, appearance, and disappearance of speckles to derive network flows and maps of the rate of filament assembly and disassembly...
  6. pmc The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
    Michelle C Mendoza
    Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
    Trends Biochem Sci 36:320-8. 2011
    ..The extent of this cross-talk and its significance in cancer therapeutics are now becoming clear...
  7. pmc p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling
    Yuki Abe
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 284:14939-48. 2009
    ..Although the molecular mechanism of CCTbeta regulation remains unclear, our findings demonstrate a link between oncogene and growth factor signaling and chaperonin CCT-mediated cellular activities...