Nilesh M Mehta

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Nutritional Status and Nutrient Intake Challenges in Children With Spinal Muscular Atrophy
    Nilesh M Mehta
    Division of Critical Care Medicine, Department of Anesthesiology, Perioperative, and Pain Medicine, Boston Children s Hospital, Boston, Massachusetts Center for Nutrition, Boston Children s Hospital, Boston, Massachusetts Harvard Medical School, Boston, Massachusetts Electronic address
    Pediatr Neurol 57:80-3. 2016
  2. pmc Adequate enteral protein intake is inversely associated with 60-d mortality in critically ill children: a multicenter, prospective, cohort study
    Nilesh M Mehta
    Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, and Center for Nutrition, Division of Gastroenterology, Hepatology and Nutrition, Boston Children s Hospital, Boston, MA Harvard Medical School, Boston, MA and
    Am J Clin Nutr 102:199-206. 2015
  3. pmc Accuracy of a simplified equation for energy expenditure based on bedside volumetric carbon dioxide elimination measurement--a two-center study
    Nilesh M Mehta
    Boston Children s Hospital, Boston, MA, United States Harvard Medical School, Boston, MA, United States Electronic address
    Clin Nutr 34:151-5. 2015
  4. doi request reprint Defining pediatric malnutrition: a paradigm shift toward etiology-related definitions
    Nilesh M Mehta
    Department of Anesthesiology, Pain and Perioperative Medicine, Boston Children s Hospital, MSICU Office, Bader 634 Children s Hospital, Boston, Massachusetts 2115, USA
    JPEN J Parenter Enteral Nutr 37:460-81. 2013
  5. pmc Resting energy expenditure after Fontan surgery in children with single-ventricle heart defects
    Nilesh M Mehta
    Division of Critical Care Medicine Anesthesia, Department of Anesthesiology, Pain and Perioperative Medicine, Children s Hospital Boston, Harvard Medical School, Bader 634, MSICU Office, 300 Longwood Ave, Boston, MA 02115, USA
    JPEN J Parenter Enteral Nutr 36:685-92. 2012
  6. pmc Nutritional practices and their relationship to clinical outcomes in critically ill children--an international multicenter cohort study*
    Nilesh M Mehta
    Division of Critical Care Medicine, Department of Anesthesiology, Pain and Perioperative Medicine at Children s Hospital Boston, Boston, MA, USA
    Crit Care Med 40:2204-11. 2012
  7. ncbi request reprint Potential drug sequestration during extracorporeal membrane oxygenation: results from an ex vivo experiment
    Nilesh M Mehta
    Children s Hospital, Farley 517, Division of Critical Care Medicine, 300 Longwood Avenue, Boston 02115, MA, USA
    Intensive Care Med 33:1018-24. 2007
  8. doi request reprint Factors associated with survival in pediatric extracorporeal membrane oxygenation--a single-center experience
    Nilesh M Mehta
    Division of Critical Care Medicine Anesthesia, Children s Hospital Boston, Boston, MA 02115, USA
    J Pediatr Surg 45:1995-2003. 2010
  9. pmc Nutritional deficiencies during critical illness
    Nilesh M Mehta
    Division of Critical Care Medicine, Department of Anesthesia, Bader 634, Children s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Pediatr Clin North Am 56:1143-60. 2009
  10. doi request reprint Challenges to optimal enteral nutrition in a multidisciplinary pediatric intensive care unit
    Nilesh M Mehta
    Division of Critical Care, Department of Anesthesia, Department of Nursing, Division of Gastroenterology, and Nutrition and Clinical Research Program, Biostatistics Core, at Children s Hospital Boston, Boston, Massachusetts 02115, USA
    JPEN J Parenter Enteral Nutr 34:38-45. 2010

Collaborators

Detail Information

Publications33

  1. doi request reprint Nutritional Status and Nutrient Intake Challenges in Children With Spinal Muscular Atrophy
    Nilesh M Mehta
    Division of Critical Care Medicine, Department of Anesthesiology, Perioperative, and Pain Medicine, Boston Children s Hospital, Boston, Massachusetts Center for Nutrition, Boston Children s Hospital, Boston, Massachusetts Harvard Medical School, Boston, Massachusetts Electronic address
    Pediatr Neurol 57:80-3. 2016
    ..We aimed to describe the nutritional status and nutrient intake in children with spinal muscular atrophy...
  2. pmc Adequate enteral protein intake is inversely associated with 60-d mortality in critically ill children: a multicenter, prospective, cohort study
    Nilesh M Mehta
    Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, and Center for Nutrition, Division of Gastroenterology, Hepatology and Nutrition, Boston Children s Hospital, Boston, MA Harvard Medical School, Boston, MA and
    Am J Clin Nutr 102:199-206. 2015
    ..The impact of protein intake on outcomes in pediatric critical illness is unclear...
  3. pmc Accuracy of a simplified equation for energy expenditure based on bedside volumetric carbon dioxide elimination measurement--a two-center study
    Nilesh M Mehta
    Boston Children s Hospital, Boston, MA, United States Harvard Medical School, Boston, MA, United States Electronic address
    Clin Nutr 34:151-5. 2015
    ..We aimed to examine the accuracy of a simplified equation for predicting REE using carbon dioxide elimination (VCO2) values...
  4. doi request reprint Defining pediatric malnutrition: a paradigm shift toward etiology-related definitions
    Nilesh M Mehta
    Department of Anesthesiology, Pain and Perioperative Medicine, Boston Children s Hospital, MSICU Office, Bader 634 Children s Hospital, Boston, Massachusetts 2115, USA
    JPEN J Parenter Enteral Nutr 37:460-81. 2013
    ..A uniform definition should permit future research to focus on the impact of pediatric malnutrition on functional outcomes and help solidify the scientific basis for evidence-based nutrition practices...
  5. pmc Resting energy expenditure after Fontan surgery in children with single-ventricle heart defects
    Nilesh M Mehta
    Division of Critical Care Medicine Anesthesia, Department of Anesthesiology, Pain and Perioperative Medicine, Children s Hospital Boston, Harvard Medical School, Bader 634, MSICU Office, 300 Longwood Ave, Boston, MA 02115, USA
    JPEN J Parenter Enteral Nutr 36:685-92. 2012
    ..Data on resting energy expenditure (REE) and oxygen consumption (VO(2)) after pediatric cardiopulmonary bypass (CPB) will facilitate optimal nutrient prescription...
  6. pmc Nutritional practices and their relationship to clinical outcomes in critically ill children--an international multicenter cohort study*
    Nilesh M Mehta
    Division of Critical Care Medicine, Department of Anesthesiology, Pain and Perioperative Medicine at Children s Hospital Boston, Boston, MA, USA
    Crit Care Med 40:2204-11. 2012
    ..To examine factors influencing the adequacy of energy and protein intake in the pediatric intensive care unit and to describe their relationship to clinical outcomes in mechanically ventilated children...
  7. ncbi request reprint Potential drug sequestration during extracorporeal membrane oxygenation: results from an ex vivo experiment
    Nilesh M Mehta
    Children s Hospital, Farley 517, Division of Critical Care Medicine, 300 Longwood Avenue, Boston 02115, MA, USA
    Intensive Care Med 33:1018-24. 2007
    ..Using an ex vivo simulation model we set out to estimate the amount of drug lost due to sequestration within the extracorporeal circuit over time...
  8. doi request reprint Factors associated with survival in pediatric extracorporeal membrane oxygenation--a single-center experience
    Nilesh M Mehta
    Division of Critical Care Medicine Anesthesia, Children s Hospital Boston, Boston, MA 02115, USA
    J Pediatr Surg 45:1995-2003. 2010
    ..We aimed to examine outcomes of extracorporeal membrane oxygenation (ECMO) therapy in the pediatric population and identify pre-ECMO and on-ECMO characteristics that are associated with survival...
  9. pmc Nutritional deficiencies during critical illness
    Nilesh M Mehta
    Division of Critical Care Medicine, Department of Anesthesia, Bader 634, Children s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Pediatr Clin North Am 56:1143-60. 2009
    ....
  10. doi request reprint Challenges to optimal enteral nutrition in a multidisciplinary pediatric intensive care unit
    Nilesh M Mehta
    Division of Critical Care, Department of Anesthesia, Department of Nursing, Division of Gastroenterology, and Nutrition and Clinical Research Program, Biostatistics Core, at Children s Hospital Boston, Boston, Massachusetts 02115, USA
    JPEN J Parenter Enteral Nutr 34:38-45. 2010
    ..Clinical characteristics, time to reach caloric goal, and parenteral nutrition (PN) use were compared between patients with and without avoidable interruptions to EN...
  11. doi request reprint Approach to enteral feeding in the PICU
    Nilesh M Mehta
    Division of Critical Care Medicine, Children s Hospital, Boston, MA 02115, USA
    Nutr Clin Pract 24:377-87. 2009
    ..The rationale and challenges to the delivery and maintenance of optimal EN, and strategies to achieve optimal EN during critical illness, are discussed...
  12. pmc Cumulative energy imbalance in the pediatric intensive care unit: role of targeted indirect calorimetry
    Nilesh M Mehta
    Divisions of Critical Care Medicine and Gastroenterology and Nutrition, Children s Hospital, Boston, MA, USA
    JPEN J Parenter Enteral Nutr 33:336-44. 2009
    ..Failure to accurately estimate energy requirements may result in underfeeding or overfeeding. In this study, a dedicated multidisciplinary nutrition team measured energy expenditure in critically ill children...
  13. pmc Energy imbalance and the risk of overfeeding in critically ill children
    Nilesh M Mehta
    Division of Critical Care Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    Pediatr Crit Care Med 12:398-405. 2011
    ....
  14. doi request reprint Systematic review of the influence of energy and protein intake on protein balance in critically ill children
    Lori J Bechard
    Division of Gastroenterology, Children s Hospital Boston, Boston, MA 02115, USA
    J Pediatr 161:333-9.e1. 2012
    ..To examine the influence of protein and energy intakes on protein balance in children receiving mechanical ventilation in the pediatric intensive care unit...
  15. doi request reprint Severe weight loss and hypermetabolic paroxysmal dysautonomia following hypoxic ischemic brain injury: the role of indirect calorimetry in the intensive care unit
    Nilesh M Mehta
    Division of Critical Care Medicine Children s Hospital, Boston, MA 02115, USA
    JPEN J Parenter Enteral Nutr 32:281-4. 2008
    ..In hospitalized patients with metabolic fluctuations, accurate measurement of energy requirements by indirect calorimetry allows serial monitoring of energy balance and may guide nutrition intake to prevent cumulative energy deficits...
  16. doi request reprint Impact of Individualized Diet Intervention on Body Composition and Respiratory Variables in Children With Respiratory Insufficiency: A Pilot Intervention Study
    Enid E Martinez
    1Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children s Hospital, Boston, MA 2Harvard Medical School, Boston, MA 3Division of Gastroenterology, Hepatology and Nutrition, Boston Children s Hospital, Boston, MA
    Pediatr Crit Care Med 16:e157-64. 2015
    ..Our objective was to examine the effect of an individualized diet intervention on changes in weight, lean body mass, minute ventilation, and volumetric CO2 production in children dependent on long-term mechanical ventilatory support...
  17. pmc Influence of obesity on clinical outcomes in hospitalized children: a systematic review
    Lori J Bechard
    Center for Nutrition, Divisions of Gastroenterology and Nutrition, Boston Children s Hospital, Boston, MA 02115, USA
    JAMA Pediatr 167:476-82. 2013
    ..Obesity is prevalent among hospitalized children. Knowledge of the relationship between obesity and outcomes in hospitalized children will enhance nutrition assessment and provide opportunities for interventions...
  18. doi request reprint Metabolic assessment and individualized nutrition in children dependent on mechanical ventilation at home
    Enid E Martinez
    Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children s Hospital, Boston, MA Harvard Medical School, Boston, MA
    J Pediatr 166:350-7. 2015
    ..To evaluate the nutritional and metabolic status and body composition of children on long-term mechanical ventilation using a home-based model...
  19. doi request reprint Gas exchange measurement during pediatric mechanical ventilation--agreement between gas sampling at the airway and the ventilator exhaust
    Craig D Smallwood
    Respiratory Care Department, Boston Children s Hospital, USA
    Clin Nutr 32:988-92. 2013
    ..The aim of this investigation was to compare oxygen consumption (VO2), carbon dioxide elimination (VCO2), REE and respiratory quotient (RQ) in mechanically ventilated children, obtained by 2 devices using distinct gas sampling methods...
  20. ncbi request reprint Mechanical ventilation in children with acute respiratory failure
    Nilesh M Mehta
    Medical Surgical Intensive Care Unit, Department of Anesthesia Children s Hospital, Boston, Massachusetts, USA
    Curr Opin Crit Care 10:7-12. 2004
    ....
  21. doi request reprint Accuracy of abbreviated indirect calorimetry protocols for energy expenditure measurement in critically ill children
    Craig D Smallwood
    Department of Respiratory Care at Children s Hospital Boston, Boston, Massachusetts, USA
    JPEN J Parenter Enteral Nutr 36:693-9. 2012
    ..Steady-state (SS) REE obtained using a 5-minute protocol (SS5) has been used as a surrogate for 24-hour REE measurement. However, SS5 conditions are difficult to achieve in critically ill children on mechanical ventilatory support...
  22. doi request reprint Nutritional outcomes in survivors of congenital diaphragmatic hernia (CDH)-factors associated with growth at one year
    Sigrid Bairdain
    Department of Pediatric Surgery, Boston Children s Hospital, and Harvard Medical School, Boston, MA, United States
    J Pediatr Surg 50:74-7. 2015
    ..We aimed to describe the nutritional status and factors that impact growth over the 12-months following discharge from the pediatric intensive care unit (PICU) in this cohort...
  23. pmc A stepwise enteral nutrition algorithm for critically ill children helps achieve nutrient delivery goals*
    Susan Hamilton
    1Department of Cardiovascular Critical Care Nursing, Boston Children s Hospital, Boston, MA 2Division of Gastroenterology, Hepatology and Nutrition, Boston Children s Hospital, Boston, MA 3Critical Care Medicine, Department of Anesthesiology, Pain and Perioperative Medicine, Boston Children s Hospital, Boston, MA
    Pediatr Crit Care Med 15:583-9. 2014
    ..To evaluate the impact of implementing an enteral nutrition algorithm on achieving optimal enteral nutrition delivery in the PICU...
  24. pmc Comparison of body composition assessment methods in pediatric intestinal failure
    Nilesh M Mehta
    Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine Division of Gastroenterology, Hepatology and Nutrition Department of Surgery Clinical and Translational Study Unit Clinical Research Center, Boston Children s Hospital and Harvard Medical School, Boston, MA
    J Pediatr Gastroenterol Nutr 59:99-105. 2014
    ..The aim of the study was to examine the agreement of multifrequency bioelectric impedance analysis (BIA) and anthropometry with reference methods for body composition assessment in children with intestinal failure (IF)...
  25. doi request reprint Current applications of metabolic monitoring in the pediatric intensive care unit
    Nilesh M Mehta
    Division of Critical Care Medicine, Department of Anaesthesia, Perioperative and Pain Medicine, Boston Children s Hospital, Boston, Massachusetts
    Nutr Clin Pract 29:338-47. 2014
    ..Basic concepts, available monitoring devices, indications, pitfalls, and bedside application of metabolic monitoring are discussed in this article. ..
  26. doi request reprint A Comparison of Carbon Dioxide Elimination Measurements Between a Portable Indirect Calorimeter and Volumetric Capnography Monitor: An In Vitro Simulation
    Craig D Smallwood
    Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children s Hospital, and Harvard Medical School, Boston, Massachusetts
    Respir Care 61:354-8. 2016
    ..We have recently suggested that measuring V̇CO2 may be sufficient to obtain a reasonable estimate of energy expenditure. However, data describing the accuracy of gas exchange measurement devices are limited...
  27. doi request reprint Challenges to nutrition therapy in the pediatric critically ill obese patient
    Enid E Martinez
    Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children s Hospital, Boston, Massachusetts Harvard Medical School, Boston, Massachusetts
    Nutr Clin Pract 30:432-9. 2015
    ..Obesity has been associated with poor clinical outcomes in critically ill children. The optimal approach to nutrition therapy in this vulnerable cohort is unclear...
  28. doi request reprint Worldwide Survey of Nutritional Practices in PICUs
    Dorian Kerklaan
    1Intensive Care Unit, Department of Paediatrics and Pediatric Surgery, Erasmus Medical Centre, Sophia Children s Hospital, Rotterdam, The Netherlands 2Clinical Division and Laboratory of Intensive Care Medicine, Department Cellular and Molecular Medicine, KU Leuven University, Leuven, Belgium 3Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, and Center for Nutrition, Division of Gastroenterology, Hepatology and Nutrition, Boston Children s Hospital, Harvard Medical School, Boston, MA 4Department of Biostatistics, Erasmus MC, Rotterdam, the Netherlands 5Department of Pediatric Gastroenterology, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    Pediatr Crit Care Med 17:10-8. 2016
    ..To assess current nutritional practices in critically ill children worldwide...
  29. doi request reprint Carbon dioxide elimination and oxygen consumption in mechanically ventilated children
    Craig D Smallwood
    Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine Harvard Medical School, Boston, Massachusetts
    Respir Care 60:718-23. 2015
    ..We also aimed to examine the characteristics of V̇CO2 values that are associated with standard steady state (5-min period when V̇CO2 and V̇O2 variability are < 10%)...
  30. doi request reprint Variability of resting energy expenditure in infants and young children with intestinal failure-associated liver disease
    Debora Duro
    Division of GI Nutrition Center for Clinical Research Department of Surgery Department of Critical Care, Boston Children s Hospital Burn Unit, Massachusetts General Hospital and Shriners Hospital for Children, Boston, MA
    J Pediatr Gastroenterol Nutr 58:637-41. 2014
    ....
  31. doi request reprint Gastric Dysmotility in Critically Ill Children: Pathophysiology, Diagnosis, and Management
    Enid E Martinez
    1Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children s Hospital, Boston, MA 2Harvard Medical School, Boston, MA 3School of Arts and Sciences, Providence College, Providence, RI 4Division of Gastroenterology, Hepatology and Nutrition, Boston Children s Hospital, Boston, MA
    Pediatr Crit Care Med 16:828-36. 2015
    ....
  32. doi request reprint Nutrition algorithms and bedside nutrient delivery practices in pediatric intensive care units: an international multicenter cohort study
    Enid E Martinez
    Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children s Hospital, Boston, Massachusetts
    Nutr Clin Pract 29:360-7. 2014
    ..Enteral nutrition (EN) delivery is associated with improved outcomes in critically ill patients. We aimed to describe EN practices, including details of algorithms and individual bedside practices, in pediatric intensive care units (PICUs)...
  33. ncbi request reprint Genetic polymorphisms in acute respiratory distress syndrome: new approach to an old problem
    Nilesh M Mehta
    Crit Care Med 33:2443-5. 2005