Nilesh M Mehta
Affiliation: Harvard University
- Defining pediatric malnutrition: a paradigm shift toward etiology-related definitionsNilesh M Mehta
Department of Anesthesiology, Pain and Perioperative Medicine, Boston Children s Hospital, MSICU Office, Bader 634 Children s Hospital, Boston, Massachusetts 2115, USA
JPEN J Parenter Enteral Nutr 37:460-81. 2013..A uniform definition should permit future research to focus on the impact of pediatric malnutrition on functional outcomes and help solidify the scientific basis for evidence-based nutrition practices...
- Resting energy expenditure after Fontan surgery in children with single-ventricle heart defectsNilesh M Mehta
Division of Critical Care Medicine Anesthesia, Department of Anesthesiology, Pain and Perioperative Medicine, Children s Hospital Boston, Harvard Medical School, Bader 634, MSICU Office, 300 Longwood Ave, Boston, MA 02115, USA
JPEN J Parenter Enteral Nutr 36:685-92. 2012..Data on resting energy expenditure (REE) and oxygen consumption (VO(2)) after pediatric cardiopulmonary bypass (CPB) will facilitate optimal nutrient prescription...
- Nutritional practices and their relationship to clinical outcomes in critically ill children--an international multicenter cohort study*Nilesh M Mehta
Division of Critical Care Medicine, Department of Anesthesiology, Pain and Perioperative Medicine at Children s Hospital Boston, Boston, MA, USA
Crit Care Med 40:2204-11. 2012..To examine factors influencing the adequacy of energy and protein intake in the pediatric intensive care unit and to describe their relationship to clinical outcomes in mechanically ventilated children...
- Energy imbalance and the risk of overfeeding in critically ill childrenNilesh M Mehta
Division of Critical Care Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
Pediatr Crit Care Med 12:398-405. 2011....
- Nutritional deficiencies during critical illnessNilesh M Mehta
Division of Critical Care Medicine, Department of Anesthesia, Bader 634, Children s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Pediatr Clin North Am 56:1143-60. 2009....
- Challenges to optimal enteral nutrition in a multidisciplinary pediatric intensive care unitNilesh M Mehta
Division of Critical Care, Department of Anesthesia, Department of Nursing, Division of Gastroenterology, and Nutrition and Clinical Research Program, Biostatistics Core, at Children s Hospital Boston, Boston, Massachusetts 02115, USA
JPEN J Parenter Enteral Nutr 34:38-45. 2010..Clinical characteristics, time to reach caloric goal, and parenteral nutrition (PN) use were compared between patients with and without avoidable interruptions to EN...
- Approach to enteral feeding in the PICUNilesh M Mehta
Division of Critical Care Medicine, Children s Hospital, Boston, MA 02115, USA
Nutr Clin Pract 24:377-87. 2009..The rationale and challenges to the delivery and maintenance of optimal EN, and strategies to achieve optimal EN during critical illness, are discussed...
- Cumulative energy imbalance in the pediatric intensive care unit: role of targeted indirect calorimetryNilesh M Mehta
Divisions of Critical Care Medicine and Gastroenterology and Nutrition, Children s Hospital, Boston, MA, USA
JPEN J Parenter Enteral Nutr 33:336-44. 2009..Failure to accurately estimate energy requirements may result in underfeeding or overfeeding. In this study, a dedicated multidisciplinary nutrition team measured energy expenditure in critically ill children...
- Potential drug sequestration during extracorporeal membrane oxygenation: results from an ex vivo experimentNilesh M Mehta
Children s Hospital, Farley 517, Division of Critical Care Medicine, 300 Longwood Avenue, Boston 02115, MA, USA
Intensive Care Med 33:1018-24. 2007..Using an ex vivo simulation model we set out to estimate the amount of drug lost due to sequestration within the extracorporeal circuit over time...
- Factors associated with survival in pediatric extracorporeal membrane oxygenation--a single-center experienceNilesh M Mehta
Division of Critical Care Medicine Anesthesia, Children s Hospital Boston, Boston, MA 02115, USA
J Pediatr Surg 45:1995-2003. 2010..We aimed to examine outcomes of extracorporeal membrane oxygenation (ECMO) therapy in the pediatric population and identify pre-ECMO and on-ECMO characteristics that are associated with survival...
- Systematic review of the influence of energy and protein intake on protein balance in critically ill childrenLori J Bechard
Division of Gastroenterology, Children s Hospital Boston, Boston, MA 02115, USA
J Pediatr 161:333-9.e1. 2012..To examine the influence of protein and energy intakes on protein balance in children receiving mechanical ventilation in the pediatric intensive care unit...
- Severe weight loss and hypermetabolic paroxysmal dysautonomia following hypoxic ischemic brain injury: the role of indirect calorimetry in the intensive care unitNilesh M Mehta
Division of Critical Care Medicine Children s Hospital, Boston, MA 02115, USA
JPEN J Parenter Enteral Nutr 32:281-4. 2008..In hospitalized patients with metabolic fluctuations, accurate measurement of energy requirements by indirect calorimetry allows serial monitoring of energy balance and may guide nutrition intake to prevent cumulative energy deficits...
- Influence of obesity on clinical outcomes in hospitalized children: a systematic reviewLori J Bechard
Center for Nutrition, Divisions of Gastroenterology and Nutrition, Boston Children s Hospital, Boston, MA 02115, USA
JAMA Pediatr 167:476-82. 2013..Obesity is prevalent among hospitalized children. Knowledge of the relationship between obesity and outcomes in hospitalized children will enhance nutrition assessment and provide opportunities for interventions...
- Mechanical ventilation in children with acute respiratory failureNilesh M Mehta
Medical Surgical Intensive Care Unit, Department of Anesthesia Children s Hospital, Boston, Massachusetts, USA
Curr Opin Crit Care 10:7-12. 2004....
- Accuracy of abbreviated indirect calorimetry protocols for energy expenditure measurement in critically ill childrenCraig D Smallwood
Department of Respiratory Care at Children s Hospital Boston, Boston, Massachusetts, USA
JPEN J Parenter Enteral Nutr 36:693-9. 2012..Steady-state (SS) REE obtained using a 5-minute protocol (SS5) has been used as a surrogate for 24-hour REE measurement. However, SS5 conditions are difficult to achieve in critically ill children on mechanical ventilatory support...
- Gas exchange measurement during pediatric mechanical ventilation--agreement between gas sampling at the airway and the ventilator exhaustCraig D Smallwood
Respiratory Care Department, Boston Children s Hospital, USA
Clin Nutr 32:988-92. 2013..The aim of this investigation was to compare oxygen consumption (VO2), carbon dioxide elimination (VCO2), REE and respiratory quotient (RQ) in mechanically ventilated children, obtained by 2 devices using distinct gas sampling methods...
- Genetic polymorphisms in acute respiratory distress syndrome: new approach to an old problemNilesh M Mehta
Crit Care Med 33:2443-5. 2005