Nilesh M Mehta
Affiliation: Harvard University
- Defining pediatric malnutrition: a paradigm shift toward etiology-related definitionsNilesh M Mehta
Department of Anesthesiology, Pain and Perioperative Medicine, Boston Children s Hospital, MSICU Office, Bader 634 Children s Hospital, Boston, Massachusetts 2115, USA
JPEN J Parenter Enteral Nutr 37:460-81. 2013..A uniform definition should permit future research to focus on the impact of pediatric malnutrition on functional outcomes and help solidify the scientific basis for evidence-based nutrition practices...
- Resting energy expenditure after Fontan surgery in children with single-ventricle heart defectsNilesh M Mehta
Division of Critical Care Medicine Anesthesia, Department of Anesthesiology, Pain and Perioperative Medicine, Children s Hospital Boston, Harvard Medical School, Bader 634, MSICU Office, 300 Longwood Ave, Boston, MA 02115, USA
JPEN J Parenter Enteral Nutr 36:685-92. 2012..Data on resting energy expenditure (REE) and oxygen consumption (VO(2)) after pediatric cardiopulmonary bypass (CPB) will facilitate optimal nutrient prescription...
- Nutritional practices and their relationship to clinical outcomes in critically ill children--an international multicenter cohort study*Nilesh M Mehta
Division of Critical Care Medicine, Department of Anesthesiology, Pain and Perioperative Medicine at Children s Hospital Boston, Boston, MA, USA
Crit Care Med 40:2204-11. 2012..To examine factors influencing the adequacy of energy and protein intake in the pediatric intensive care unit and to describe their relationship to clinical outcomes in mechanically ventilated children...
- Energy imbalance and the risk of overfeeding in critically ill childrenNilesh M Mehta
Division of Critical Care Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
Pediatr Crit Care Med 12:398-405. 2011....
- Factors associated with survival in pediatric extracorporeal membrane oxygenation--a single-center experienceNilesh M Mehta
Division of Critical Care Medicine Anesthesia, Children s Hospital Boston, Boston, MA 02115, USA
J Pediatr Surg 45:1995-2003. 2010..We aimed to examine outcomes of extracorporeal membrane oxygenation (ECMO) therapy in the pediatric population and identify pre-ECMO and on-ECMO characteristics that are associated with survival...
- Nutritional deficiencies during critical illnessNilesh M Mehta
Division of Critical Care Medicine, Department of Anesthesia, Bader 634, Children s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Pediatr Clin North Am 56:1143-60. 2009....
- Challenges to optimal enteral nutrition in a multidisciplinary pediatric intensive care unitNilesh M Mehta
Division of Critical Care, Department of Anesthesia, Department of Nursing, Division of Gastroenterology, and Nutrition and Clinical Research Program, Biostatistics Core, at Children s Hospital Boston, Boston, Massachusetts 02115, USA
JPEN J Parenter Enteral Nutr 34:38-45. 2010..Clinical characteristics, time to reach caloric goal, and parenteral nutrition (PN) use were compared between patients with and without avoidable interruptions to EN...
- Approach to enteral feeding in the PICUNilesh M Mehta
Division of Critical Care Medicine, Children s Hospital, Boston, MA 02115, USA
Nutr Clin Pract 24:377-87. 2009..The rationale and challenges to the delivery and maintenance of optimal EN, and strategies to achieve optimal EN during critical illness, are discussed...
- Cumulative energy imbalance in the pediatric intensive care unit: role of targeted indirect calorimetryNilesh M Mehta
Divisions of Critical Care Medicine and Gastroenterology and Nutrition, Children s Hospital, Boston, MA, USA
JPEN J Parenter Enteral Nutr 33:336-44. 2009..Failure to accurately estimate energy requirements may result in underfeeding or overfeeding. In this study, a dedicated multidisciplinary nutrition team measured energy expenditure in critically ill children...
- Potential drug sequestration during extracorporeal membrane oxygenation: results from an ex vivo experimentNilesh M Mehta
Children s Hospital, Farley 517, Division of Critical Care Medicine, 300 Longwood Avenue, Boston 02115, MA, USA
Intensive Care Med 33:1018-24. 2007..Using an ex vivo simulation model we set out to estimate the amount of drug lost due to sequestration within the extracorporeal circuit over time...
- Systematic review of the influence of energy and protein intake on protein balance in critically ill childrenLori J Bechard
Division of Gastroenterology, Children s Hospital Boston, Boston, MA 02115, USA
J Pediatr 161:333-9.e1. 2012..To examine the influence of protein and energy intakes on protein balance in children receiving mechanical ventilation in the pediatric intensive care unit...
- Severe weight loss and hypermetabolic paroxysmal dysautonomia following hypoxic ischemic brain injury: the role of indirect calorimetry in the intensive care unitNilesh M Mehta
Division of Critical Care Medicine Children s Hospital, Boston, MA 02115, USA
JPEN J Parenter Enteral Nutr 32:281-4. 2008..In hospitalized patients with metabolic fluctuations, accurate measurement of energy requirements by indirect calorimetry allows serial monitoring of energy balance and may guide nutrition intake to prevent cumulative energy deficits...
- Influence of obesity on clinical outcomes in hospitalized children: a systematic reviewLori J Bechard
Center for Nutrition, Divisions of Gastroenterology and Nutrition, Boston Children s Hospital, Boston, MA 02115, USA
JAMA Pediatr 167:476-82. 2013..Obesity is prevalent among hospitalized children. Knowledge of the relationship between obesity and outcomes in hospitalized children will enhance nutrition assessment and provide opportunities for interventions...
- Gas exchange measurement during pediatric mechanical ventilation--agreement between gas sampling at the airway and the ventilator exhaustCraig D Smallwood
Respiratory Care Department, Boston Children s Hospital, USA
Clin Nutr 32:988-92. 2013..The aim of this investigation was to compare oxygen consumption (VO2), carbon dioxide elimination (VCO2), REE and respiratory quotient (RQ) in mechanically ventilated children, obtained by 2 devices using distinct gas sampling methods...
- Mechanical ventilation in children with acute respiratory failureNilesh M Mehta
Medical Surgical Intensive Care Unit, Department of Anesthesia Children s Hospital, Boston, Massachusetts, USA
Curr Opin Crit Care 10:7-12. 2004....
- Variability of resting energy expenditure in infants and young children with intestinal failure-associated liver diseaseDebora Duro
Division of GI Nutrition Center for Clinical Research Department of Surgery Department of Critical Care, Boston Children s Hospital Burn Unit, Massachusetts General Hospital and Shriners Hospital for Children, Boston, MA
J Pediatr Gastroenterol Nutr 58:637-41. 2014....
- Accuracy of abbreviated indirect calorimetry protocols for energy expenditure measurement in critically ill childrenCraig D Smallwood
Department of Respiratory Care at Children s Hospital Boston, Boston, Massachusetts, USA
JPEN J Parenter Enteral Nutr 36:693-9. 2012..Steady-state (SS) REE obtained using a 5-minute protocol (SS5) has been used as a surrogate for 24-hour REE measurement. However, SS5 conditions are difficult to achieve in critically ill children on mechanical ventilatory support...
- Current applications of metabolic monitoring in the pediatric intensive care unitNilesh M Mehta
Division of Critical Care Medicine, Department of Anaesthesia, Perioperative and Pain Medicine, Boston Children s Hospital, Boston, Massachusetts
Nutr Clin Pract 29:338-47. 2014..Basic concepts, available monitoring devices, indications, pitfalls, and bedside application of metabolic monitoring are discussed in this article. ..
- Nutrition algorithms and bedside nutrient delivery practices in pediatric intensive care units: an international multicenter cohort studyEnid E Martinez
Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children s Hospital, Boston, Massachusetts
Nutr Clin Pract 29:360-7. 2014..Enteral nutrition (EN) delivery is associated with improved outcomes in critically ill patients. We aimed to describe EN practices, including details of algorithms and individual bedside practices, in pediatric intensive care units (PICUs)...
- Genetic polymorphisms in acute respiratory distress syndrome: new approach to an old problemNilesh M Mehta
Crit Care Med 33:2443-5. 2005