Affiliation: Harvard University
- Age- and time-related changes in extracellular viral load in children vertically infected by human immunodeficiency virusK McIntosh
Division of Infectious Diseases, Children s Hospital, Boston MA 02115, USA
Pediatr Infect Dis J 15:1087-91. 1996..Information on the natural history of circulating extracellular virus will be useful in elucidating the pathogenesis of pediatric HIV infection and in using viral load measurement to guide prognosis and therapy...
- Antiretroviral regimens in pregnancy and breast-feeding in BotswanaR L Shapiro
Division of Infectious Diseases, Beth Israel Deaconess Medical Center, 110 Francis St, Suite GB, Boston, MA 02215, USA
N Engl J Med 362:2282-94. 2010..The most effective highly active antiretroviral therapy (HAART) to prevent mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) in pregnancy and its efficacy during breast-feeding are unknown...
- Left ventricular structure and function in children infected with human immunodeficiency virus: the prospective P2C2 HIV Multicenter Study. Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection (P2C2 HIV) Study GroupS E Lipshultz
Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, Mass, USA
Circulation 97:1246-56. 1998..The frequency of, course of, and factors associated with cardiovascular abnormalities in pediatric HIV are incompletely understood...
- Toxicity and efficacy of daily vs. weekly dapsone for prevention of Pneumocystis carinii pneumonia in children infected with human immunodeficiency virus. ACTG 179 Study Team. AIDS Clinical Trials GroupK McIntosh
Children s Hospital, Division of Infectious Diseases, Boston, MA 02115, USA
Pediatr Infect Dis J 18:432-9. 1999..Design. Randomized, multicenter trial comparing daily (1 or 2 mg/kg) with weekly (4 mg/kg) dapsone regimens in 94 HIV-infected children intolerant to T/S...
- Immunologic response to combination nucleoside analogue plus protease inhibitor therapy in stable antiretroviral therapy-experienced human immunodeficiency virus-infected childrenW Borkowsky
Division of Infectious Diseases, New York University School of Medicine, New York, NY 10016, USA
J Infect Dis 182:96-103. 2000..02) by week 48 in this clinically stable population. Changes in lymphoproliferative responses to HIV antigens and recall antigens did not increase over time and between groups...
- Predictors of incident tuberculosis among HIV-1-infected women in TanzaniaP A Venkatesh
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Int J Tuberc Lung Dis 9:1105-11. 2005..The development of tuberculosis (TB) in HIV-1-infected individuals is associated with accelerated HIV-1 disease progression...
- Comprehensive screening reveals strong and broadly directed human immunodeficiency virus type 1-specific CD8 responses in perinatally infected childrenM E Feeney
Partners AIDS Research Center and Infectious Disease Division, Massachusetts General Hospital and Harvard Medical Schoo, Boston, Massachusetts, USA
J Virol 77:7492-501. 2003..Moreover, this response has the potential to be broadened to target more epitopes, making these children attractive candidates for immunotherapeutic interventions...
- Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing childM E Feeney
Partners AIDS Research Center, 5th Floor, 149 13th St, Charlestown, MA 02129, USA
J Virol 78:8927-30. 2004..This temporal pattern suggests that CD8 escape can play a causal role in the loss of immune control...