Edward R Marcantonio

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..To determine the prevalence of delirium symptoms at the time of admission to post-acute facilities, the persistence of delirium symptoms in this setting, and the association of delirium symptoms with functional recovery...

..To determine whether patients who developed delirium after cardiac surgery were at risk of functional decline...

..Screening instruments such as the Telephone Interview for Cognitive Status (TICS) were developed to provide a valid alternative, with comparable cut-point scores to rate global cognitive function...

..Hospitalization, frequently complicated by delirium, can be a life-changing event for patients with Alzheimer disease (AD)...

..To examine the rates of and risk factors for acute hospitalization in a prospective cohort of older community-dwelling patients with Alzheimer's disease (AD)...

..Delirium is an acute confusional state that is common, preventable, and life-threatening...

..82). The developed measure provided a reliable, continuous measure (reliability > .90) across a broad range of performance (-1.5 SDs to +1.0 SDs) with minimal ceiling and floor effects...

..The purpose of the present prospective study was to develop a prediction rule for delirium in a cardiac surgery cohort and to validate it in an independent cohort...

..To determine whether a delirium abatement program (DAP) can shorten duration of delirium in new admissions to postacute care (PAC)...

..To examine the association between persistent delirium and 1-year mortality in newly admitted postacute care (PAC) facility patients with delirium who were followed regardless of residence...

..To examine the mediating role between educational attainment and risk for incidence delirium of activity participation and to examine the contribution of participation in specific activities to the development of delirium...

..We hypothesized that peak postoperative BNP associates with PF assessed up to 2 yr after CABG surgery, even after adjusting for clinical risk factors. including preoperative PF...

..Meanwhile, current assessment instruments are underused, lack sensitivity, or may be restricted by copyright laws. To address these limitations, we created a new brief cognitive assessment tool: the Sweet 16...

..We sought to determine whether a rapid-response system that relied on a patient's usual care providers, not a critical-care-trained rapid-response team, would improve patient outcomes...

..The purpose of this study is to examine the association between psychomotor activity delirium subtypes and 1-year mortality among 457 newly admitted delirious PAC patients...

..To measure the prevalence of depressive symptoms, cognitive impairment, and delirium in patients with hip fracture and to estimate their effect on functional recovery, institutionalization, and death after surgical repair...

..We aimed to identify factors important to mammography screening decisions among women aged 80 and older compared to women aged 65-79...

..The purpose of this study was to compare postoperative changes in groups of inflammatory markers in persons who developed delirium following cardiac surgery and matched controls without delirium...

..We studied acute variations in gene-expression profiles of patients with neurocognitive decline (NCD group) compared with those without neurocognitive decline (NORM group) after cardiopulmonary bypass...

..Studying the role of reserve in delirium can advance prevention strategies for delirium and may advance knowledge of reserve and its role in aging and neuropsychiatric disease generally...

..We sought to determine how women aged 80 years or older value different preventive health measures compared to women aged 65 to 79 years...

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..CONCLUSION: NSE and tau are better associated with NCD and less influenced by cardiotomy suction compared with S-100beta. Inflammatory and oxidative stress is associated with NCD post-CPB...

..To compare outcomes of patients admitted to postacute skilled nursing facilities with delirium, subsyndromal delirium, and no delirium...

..To identify factors that influence the breast cancer treatment decisions of women aged 80 and older...

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..Prognostic information is becoming increasingly important for clinical decision-making...

..Generally, immunizations and exercise counseling are recommended for all women aged > or =65 years, while Pap smears are generally not encouraged for these women...

..The purpose of this study is to examine the association between delirium resolution and functional recovery in skilled nursing facilities specializing in PAC...

..We aimed to define the incidence of nosocomial GI bleeding outside of the intensive care unit and examine the association between acid-suppressive medication use and this complication...

..Among hospital survivors, impaired functional status is independently associated with increased mortality rate within 90 days...

..To examine the association between the prevalence of delirium among patients admitted to postacute care and the quality of nursing home care as reflected in deficiency counts...

..This study utilizes IRT to identify a reduced set of optimally performing screening indicators for the four CAM features of delirium...

..To use an expert consensus process to identify indicators of delirium features to help enhance bedside recognition of delirium...

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..We sought to determine whether low acculturation, based on language measures, leads to disparities in cardiovascular risk factor control in U.S. Hispanic adults...

..To examine outcomes of mammography screening among women > or = 80 years to inform decision making...

..Persistent delirium at the time of hospital discharge is associated with poor outcomes. The objectives of this study were to develop and validate a predictive model for persistent delirium at hospital discharge...

..97). While intraoperative microemboli were not associated with delirium after CABG, further investigation into the source and composition of microemboli can further elucidate the long-term clinical impact of microemboli...

..The use of acid-suppressive medication has been steadily increasing, particularly in the inpatient setting, despite lack of an accepted indication in the majority of these patients...

..To further validate an index predicting mortality in community-dwelling older adults...

..Unplanned hospitalization often represents a costly and hazardous event for the older population...

..Program adoption challenges and corresponding model refinements to enhance adherence and overall care quality are highlighted. Last, clinical adaptation of this research-derived program is discussed...

..To identify barriers and motivators to participation in long-term clinical research by high-risk elderly people and to develop procedures to maximize recruitment and retention...

..This program project was designed to contribute to our understanding of the complex multifactorial syndrome of delirium...

..The purpose of this study is to describe the prevalence of delirium, delirium symptoms, and severity assessed at admission to postacute facilities...

..To determine the extent to which preoperative performance on tests of executive function and memory was associated with delirium after coronary artery bypass graft (CABG) surgery...

..The objective of this study was to determine if level of educational attainment, a marker of cognitive reserve, was associated with the cumulative risk of delirium among hospitalized elders...

..To investigate whether atherosclerosis of the ascending aorta, internal carotid arteries, and coronary arteries is predictive of postoperative delirium in subjects undergoing coronary artery bypass graft (CABG) surgery...

..We sought to examine the use of preventive health services among older women and to assess how age and illness burden influence care patterns...

..To determine whether donepezil hydrochloride can reduce the prevalence and severity of delirium in older adults undergoing hip fracture repair...

..We hypothesized that patients who reported poor service quality were at increased risk of experiencing adverse events and medical errors...

..For-profit and nonprofit hospices may respond differently to financial incentives...

..Thus, it appears that inflammation plays a key role in NCD pathophysiology, likely via axonal CNS injury, and could become a target for prevention...

..Future studies should focus on identifying tumor and patient characteristics to help target treatments to the oldest women most likely to benefit...

..We repeated these analyses stratifying by age...

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..Despite uncertain benefit, many women over age 80 (oldest-old) receive screening mammography...

..To provide descriptive epidemiological information on identified depression in nursing home residents...

..To exfamine patient perceptions of physician discussions and recommendations about total joint arthroplasty (TJA)...

..Identifying accurate biomarkers for delirium may shed further light into its pathophysiology and on the interrelationship between delirium and dementia...

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..Subjects Naive mice, H4 human neuroglioma cells, and H4 human neuroglioma cells stably transfected to express full-length amyloid precursor protein...

..Language barriers have been shown to negatively impact health care for immigrants. We evaluated the association between language use and the diagnosis of hypertension among elderly Mexican Americans...

..To obtain information from decision makers about attitudes toward hospitalization and the factors that influence their decisions to hospitalize nursing home residents...

..To determine whether preoperative characteristics influence quality of life outcomes 1, 6, and 12 months after joint replacement surgery...

..Hospitalization decisions for nursing facility residents are complex and involve clinical and nonclinical factors...

..Nonclinicians may offer an effective alternative for the assessment of delirium among postacute patients in skilled nursing facilities...

..Understanding how the cholinergic pathway relates to delirium may yield innovative approaches in the diagnosis, prevention, and treatment of this common, costly, and morbid condition...

..We hypothesized that vascular risk factors and mildly impaired cognitive performance would independently predispose nondemented patients to develop delirium after noncardiac surgery...

..While delirium has been increasingly recognized as a serious and potentially preventable condition, its long-term implications are not well understood. This study determined the total 1-year health care costs associated with delirium...