Nicholas J Mantis

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Selective adherence of IgA to murine Peyer's patch M cells: evidence for a novel IgA receptor
    Nicholas J Mantis
    Department of Pediatrics, Harvard Medical School, and Gastrointestinal Cell Biology Laboratory, Children s Hospital, Boston, MA 02115, USA
    J Immunol 169:1844-51. 2002
  2. ncbi Analysis of adhesion molecules involved in leukocyte homing into the basolateral pockets of mouse Peyer's patch M cells
    Nicholas J Mantis
    GI Cell Biology Laboratory, Children s Hospital Boston, 300 Longwood Avenue, 02115 Boston, MA, USA
    J Drug Target 12:79-87. 2004
  3. ncbi Oligosaccharide side chains on human secretory IgA serve as receptors for ricin
    Nicholas J Mantis
    Gastrointestinal Cell Biology Laboratory, Children s Hospital Boston, and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
    J Immunol 172:6838-45. 2004
  4. pmc The viral sigma1 protein and glycoconjugates containing alpha2-3-linked sialic acid are involved in type 1 reovirus adherence to M cell apical surfaces
    Anna Helander
    GI Cell Biology Laboratory, Enders 1220, Children s Hospital and Department of Pediatrics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Virol 77:7964-77. 2003
  5. ncbi Ricin induces IL-8 secretion from human monocyte/macrophages by activating the p38 MAP kinase pathway
    Tessa V Gonzalez
    Department of Pediatrics, Harvard Medical School, and GI Cell Biology Laboratory, Children s Hospital Boston, Boston, MA 02115, USA
    Mol Immunol 43:1920-3. 2006
  6. pmc Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication
    Nicholas J Mantis
    Division of Infectious Disease, Wadsworth Center, N Y State Department of Health, 120 New Scotland Avenue, Albany, NY 12208, USA
    Infect Immun 74:3455-62. 2006
  7. pmc Characterization of a novel high-affinity monoclonal immunoglobulin G antibody against the ricin B subunit
    Carolyn R McGuinness
    Division of Infectious Disease, Wadsworth Center, 120 New Scotland Avenue, Albany, NY 12208, USA
    Infect Immun 74:3463-70. 2006
  8. pmc Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxication
    J Marina Yoder
    Division of Infectious Disease, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208, USA
    Infect Immun 75:1745-50. 2007
  9. pmc Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region
    Nicholas J Mantis
    Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208, USA
    J Immunol 179:3144-52. 2007

Collaborators

Detail Information

Publications9

  1. ncbi Selective adherence of IgA to murine Peyer's patch M cells: evidence for a novel IgA receptor
    Nicholas J Mantis
    Department of Pediatrics, Harvard Medical School, and Gastrointestinal Cell Biology Laboratory, Children s Hospital, Boston, MA 02115, USA
    J Immunol 169:1844-51. 2002
    ....
  2. ncbi Analysis of adhesion molecules involved in leukocyte homing into the basolateral pockets of mouse Peyer's patch M cells
    Nicholas J Mantis
    GI Cell Biology Laboratory, Children s Hospital Boston, 300 Longwood Avenue, 02115 Boston, MA, USA
    J Drug Target 12:79-87. 2004
    ....
  3. ncbi Oligosaccharide side chains on human secretory IgA serve as receptors for ricin
    Nicholas J Mantis
    Gastrointestinal Cell Biology Laboratory, Children s Hospital Boston, and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
    J Immunol 172:6838-45. 2004
    ..We conclude that sIgA Abs in mucosal secretions may serve as receptor analogues for ricin, thereby reducing the effective dose of toxin capable of gaining access to glycolipid and glycoprotein receptors on epithelial cell surfaces...
  4. pmc The viral sigma1 protein and glycoconjugates containing alpha2-3-linked sialic acid are involved in type 1 reovirus adherence to M cell apical surfaces
    Anna Helander
    GI Cell Biology Laboratory, Enders 1220, Children s Hospital and Department of Pediatrics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Virol 77:7964-77. 2003
    ....
  5. ncbi Ricin induces IL-8 secretion from human monocyte/macrophages by activating the p38 MAP kinase pathway
    Tessa V Gonzalez
    Department of Pediatrics, Harvard Medical School, and GI Cell Biology Laboratory, Children s Hospital Boston, Boston, MA 02115, USA
    Mol Immunol 43:1920-3. 2006
    ....
  6. pmc Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication
    Nicholas J Mantis
    Division of Infectious Disease, Wadsworth Center, N Y State Department of Health, 120 New Scotland Avenue, Albany, NY 12208, USA
    Infect Immun 74:3455-62. 2006
    ..We conclude that IgA antibodies against RTA and RTB can protect mucosal epithelial cells from ricin intoxication...
  7. pmc Characterization of a novel high-affinity monoclonal immunoglobulin G antibody against the ricin B subunit
    Carolyn R McGuinness
    Division of Infectious Disease, Wadsworth Center, 120 New Scotland Avenue, Albany, NY 12208, USA
    Infect Immun 74:3463-70. 2006
    ..Finally, we demonstrate that R70 and 24B11, when combined, function synergistically to neutralize ricin in vitro, raising the possibility that these two MAbs could serve as a novel immunotherapeutic in vivo...
  8. pmc Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxication
    J Marina Yoder
    Division of Infectious Disease, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208, USA
    Infect Immun 75:1745-50. 2007
    ....
  9. pmc Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region
    Nicholas J Mantis
    Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208, USA
    J Immunol 179:3144-52. 2007
    ....