Research Topics
Genomes and Genes
| JoAnn E MansonSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
The escalating pandemics of obesity and sedentary lifestyle. A call to action for cliniciansJoAnn E Manson
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Arch Intern Med 164:249-58. 2004..This blueprint for action, which requires only a few minutes of a clinician's time to implement, will facilitate more effective intervention related to obesity and inactivity and should favorably impact public health...
Increased mortality risk in women with depression and diabetes mellitusAn Pan
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Arch Gen Psychiatry 68:42-50. 2011..Depression and diabetes mellitus have been associated with an increased risk of all-cause and cardiovascular disease (CVD) mortality. However, data evaluating the joint effects of these 2 conditions on mortality are sparse...- Age-related cataract in a randomized trial of vitamins E and C in menWilliam G Christen
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215 1204, USA
Arch Ophthalmol 128:1397-405. 2010..To test whether supplementation with alternate-day vitamin E or daily vitamin C affects the incidence of age-related cataract in a large cohort of men... - Vitamins C and E and beta carotene supplementation and cancer risk: a randomized controlled trialJennifer Lin
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215, USA
J Natl Cancer Inst 101:14-23. 2009..However, findings from randomized trials of the association between antioxidant use and cancer risk have been mostly negative... - Alcohol consumption and breast cancer risk in the Women's Health StudyShumin M Zhang
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Am J Epidemiol 165:667-76. 2007..The findings from this prospective study suggest that moderate alcohol consumption increases breast cancer risk... - FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal womenYiqing Song
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Obesity (Silver Spring) 16:2472-80. 2008..In conclusion, common genetic variants in the intron 1 of FTO gene may confer a modest susceptibility to obesity in an ethnicity-specific manner, but may be unlikely to contribute to a clinically significant diabetes risk... - Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in womenJennifer Lin
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
Am J Clin Nutr 87:734-43. 2008..B vitamins such as folate, vitamin B-6, and vitamin B-12 are coenzymes that are important for DNA integrity and stability. Deficiency in these B vitamins may promote tumor carcinogenesis... 
Red meat consumption and mortality: results from 2 prospective cohort studiesAn Pan
Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Arch Intern Med 172:555-63. 2012..Red meat consumption has been associated with an increased risk of chronic diseases. However, its relationship with mortality remains uncertain...- Dietary glycemic index, dietary glycemic load, blood lipids, and C-reactive proteinEmily B Levitan
Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Metabolism 57:437-43. 2008..24, and TG = 13 mg/dL). Differences in blood lipids and CRP between extreme quintiles of dietary GI and GL were small, but may translate into a clinically meaningful difference in cardiovascular risk... - Consumption of trans fatty acids is related to plasma biomarkers of inflammation and endothelial dysfunctionEsther Lopez-Garcia
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
J Nutr 135:562-6. 2005.... - Phobic anxiety and risk of coronary heart disease and sudden cardiac death among womenChristine M Albert
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215 1204, USA
Circulation 111:480-7. 2005..To the best of our knowledge, no studies have looked at this association among women. Anxiety may influence CHD mortality by increasing the risk of ventricular arrhythmia and SCD... - Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunctionEsther Lopez-Garcia
Department of Nutrition and the Division of Preventive Medicine, Harvard Medical School, Boston, USA
Am J Clin Nutr 80:1029-35. 2004..Endothelial dysfunction is one of the mechanisms linking diet and the risk of cardiovascular disease... - Vitamins E and C and medical record-confirmed age-related macular degeneration in a randomized trial of male physiciansWilliam G Christen
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Ophthalmology 119:1642-9. 2012..To test whether supplementation with alternate-day vitamin E or daily vitamin C affects the incidence of the diagnosis of age-related macular degeneration (AMD) in a large-scale randomized trial of male physicians... - Magnesium intake and plasma concentrations of markers of systemic inflammation and endothelial dysfunction in womenYiqing Song
Division of Preventive Medicine and Epidemiology, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 85:1068-74. 2007..Relations between magnesium intake and systemic inflammation and endothelial dysfunction are not well established... - Sex hormone-binding globulin and risk of type 2 diabetes in women and menEric L Ding
Department of Nutrition, Harvard School of Public Health, Boston, USA
N Engl J Med 361:1152-63. 2009..Circulating sex hormone-binding globulin levels are inversely associated with insulin resistance, but whether these levels can predict the risk of developing type 2 diabetes is uncertain... - Genetic variation in sex-steroid receptors and synthesizing enzymes and colorectal cancer risk in womenJennifer Lin
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Cancer Causes Control 21:897-908. 2010.... - Vitamin C and risk of coronary heart disease in womenStavroula K Osganian
Department of Medicine, Children s Hospital, Boston, Massachusetts, USA
J Am Coll Cardiol 42:246-52. 2003..Our objective was to prospectively examine the relation between vitamin C intake and risk of coronary heart disease (CHD) in women... - Single nucleotide polymorphisms at the adiponectin locus and risk of coronary heart disease in men and womenTobias Pischon
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
Obesity (Silver Spring) 15:2051-60. 2007..The objective was to examine the association of 5 common single nucleotide polymorphisms (SNPs) at the adiponectin locus with risk of coronary heart disease (CHD) in men and women... - Sex hormone-binding globulin and serum testosterone are inversely associated with C-reactive protein levels in postmenopausal women at high risk for cardiovascular diseaseHylton V Joffe
Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital, 221 Longwood Ave, Boston, MA 02215, USA
Ann Epidemiol 16:105-12. 2006..CONCLUSIONS: SHBG and total testosterone were inversely associated with CRP among HT nonusers in this study. The relationship between SHBG and CRP was more strongly inverse among leaner women... - Effects of vitamins C and E and beta-carotene on the risk of type 2 diabetes in women at high risk of cardiovascular disease: a randomized controlled trialYiqing Song
Division of Preventive Medicine and Cardiology Division, Harvard School of Public Health, Boston, MA 02215, USA
Am J Clin Nutr 90:429-37. 2009..Vitamin C, vitamin E, and beta-carotene are major antioxidants and as such may protect against the development of type 2 diabetes via reduction of oxidative stress... - Plasma vitamin B(6) and risk of myocardial infarction in womenJohn H Page
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
Circulation 120:649-55. 2009..We prospectively evaluated the relationships between fasting plasma levels of vitamin B(6), as pyridoxal phosphate, and subsequent myocardial infarction risk in women... - Sweetened beverage consumption and risk of coronary heart disease in womenTeresa T Fung
Department of Nutrition, Simmons College, Boston, MA 02115, USA
Am J Clin Nutr 89:1037-42. 2009..Previous studies have linked full-calorie sugar-sweetened beverages (SSBs) with greater weight gain and an increased risk of type 2 diabetes... - Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trialJ Michael Gaziano
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
JAMA 301:52-62. 2009..No previous trial in men at usual risk has examined vitamin C alone in the prevention of cancer... - C-reactive protein is independently associated with fasting insulin in nondiabetic womenAruna D Pradhan
Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, 900 Commonwealth Ave E, Boston, Mass 02215-1204, USA
Arterioscler Thromb Vasc Biol 23:650-5. 2003..These data provide additional support for previously reported associations between subclinical inflammation and the risk of type 2 diabetes and cardiovascular disease... - Sexual orientation, health risk factors, and physical functioning in the Nurses' Health Study IIPatricia Case
Department of Social Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA
J Womens Health (Larchmt) 13:1033-47. 2004..To examine associations between sexual orientation and breast cancer risk factors, cardiovascular disease (CVD) risk factors, mental health status, and health-related functioning... - A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in womenPaul M Ridker
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, USA
N Engl J Med 352:1293-304. 2005.... - Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. womenYiqing Song
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Diabetes Care 28:1438-44. 2005..The aim of this study was to examine whether and to what extent magnesium intake is related to systemic inflammation and the metabolic syndrome... - Obesity as compared with physical activity in predicting risk of coronary heart disease in womenTricia Y Li
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Circulation 113:499-506. 2006..CONCLUSIONS: Obesity and physical inactivity independently contribute to the development of CHD in women. These data underscore the importance of both maintaining a healthy weight and regular physical activity in preventing CHD... - Adherence to the Mediterranean dietary pattern is positively associated with plasma adiponectin concentrations in diabetic womenChristos S Mantzoros
Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA and Nutrition, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 84:328-35. 2006..Close adherence to a Mediterranean-type diet is associated with higher adiponectin concentrations... - Bidirectional association between depression and type 2 diabetes mellitus in womenAn Pan
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Arch Intern Med 170:1884-91. 2010..Although it has been hypothesized that the diabetes-depression relation is bidirectional, few studies have addressed this hypothesis in a prospective setting... - Prospective study of major dietary patterns and stroke risk in womenTeresa T Fung
Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02115, USA
Stroke 35:2014-9. 2004..Many foods have been suggested to influence the risk of stroke. However, no previous studies have examined the relationship between overall dietary patterns and risk of stroke... - Effect of homocysteine-lowering treatment with folic Acid and B vitamins on risk of type 2 diabetes in women: a randomized, controlled trialYiqing Song
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes 58:1921-8. 2009..We investigated whether homocysteine-lowering treatment by B vitamin supplementation prevents the risk of type 2 diabetes... - Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trialChristine M Albert
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, Massachusetts 02215 1204, USA
JAMA 299:2027-36. 2008..Observational data suggest benefits may be greater among women, yet women have been underrepresented in published randomized trials... - Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of womenYiqing Song
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes 56:1898-904. 2007..S. postmenopausal women, implicating an etiological role of endothelial dysfunction in the pathogenesis of type 2 diabetes... - Eight-year change in body mass index and subsequent risk of cardiovascular disease among healthy non-smoking menThomas S Bowman
VA Boston Healthcare System Massachusetts Veterans Affairs Epidemiology, Research, and Information Center MAVERIC, Boston, MA, USA
Prev Med 45:436-41. 2007..To determine how change in BMI over 8 years is associated with risk of subsequent cardiovascular disease (CVD) among middle aged men... - Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trialHoward D Sesso
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
JAMA 300:2123-33. 2008..However, few long-term trials have evaluated men at initially low risk of cardiovascular disease, and no previous trial in men has examined vitamin C alone in the prevention of cardiovascular disease... - Beta carotene supplementation and age-related maculopathy in a randomized trial of US physiciansWilliam G Christen
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215 1204, USA
Arch Ophthalmol 125:333-9. 2007..To test whether beta carotene supplementation affects the incidence of age-related maculopathy (ARM) in a large-scale randomized trial... - Effect of combined folic acid, vitamin B6, and vitamin B12 on cancer risk in women: a randomized trialShumin M Zhang
Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
JAMA 300:2012-21. 2008..Folate, vitamin B(6), and vitamin B(12) are thought to play an important role in cancer prevention... - Low-carbohydrate-diet score and the risk of coronary heart disease in womenThomas L Halton
Departments of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
N Engl J Med 355:1991-2002. 2006..When vegetable sources of fat and protein are chosen, these diets may moderately reduce the risk of coronary heart disease... - Plasma adiponectin and the risk of hypertension in white and black postmenopausal womenLu Wang
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Clin Chem 58:1438-45. 2012..We conducted a prospective, nested case control study to investigate the relation between baseline plasma adiponectin, measures of adiposity, and subsequent risk of hypertension... - Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in womenYiqing Song
Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
BMC Med Genet 10:4. 2009..However, it is unclear whether common genetic variation in TRPM6 and TRPM7 contributes to risk of type 2 diabetes... - Major dietary protein sources and risk of coronary heart disease in womenAdam M Bernstein
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Circulation 122:876-83. 2010..Our objective was to examine the relation between foods that are major dietary protein sources and incident CHD... - Calcium/vitamin D supplementation and coronary artery calcification in the Women's Health InitiativeJoAnn E Manson
Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Menopause 17:683-91. 2010..We compared CAC scores after trial completion between women randomized to calcium/vitamin D supplementation and women randomized to placebo... - Conjugated equine estrogens and coronary heart disease: the Women's Health InitiativeJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Arch Intern Med 166:357-65. 2006..These trials did not address the role of unopposed estrogen for coronary protection... - A prospective study of trans fatty acids in erythrocytes and risk of coronary heart diseaseQi Sun
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
Circulation 115:1858-65. 2007..We assessed the hypothesis that higher trans fatty acid contents in erythrocytes were associated with an elevated risk of CHD in a nested case-control study among US women... - Alcohol consumption, weight gain, and risk of becoming overweight in middle-aged and older womenLu Wang
Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Arch Intern Med 170:453-61. 2010..Alcohol consumption is a source of energy intake that may contribute to body weight gain and development of obesity. However, previous studies of this relationship have been limited, with inconsistent results... - Plasma lycopene, other carotenoids, and the risk of type 2 diabetes in womenLu Wang
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Am J Epidemiol 164:576-85. 2006..91 (95% CI: 0.46, 1.81) for beta-cryptoxanthin, and 1.35 (95% CI: 0.68, 2.69) for lutein/zeaxanthin. There was no prospective association between baseline plasma carotenoids and the risk of type 2 diabetes in middle-aged and older women... - Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetesAsli Memisoglu
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Diabetes Care 26:2915-7. 2003..To determine whether the Pro12Ala polymorphism in the PPARgamma gene was associated with risk of type 2 diabetes in the Nurses' Health Study... - Carbohydrate intake, glycemic index, glycemic load, and dietary fiber in relation to risk of stroke in womenKyungwon Oh
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
Am J Epidemiol 161:161-9. 2005..In addition, high consumption of cereal fiber was associated with lower risk of total and hemorrhagic stroke... - Inflammatory markers and the risk of coronary heart disease in men and womenJennifer K Pai
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
N Engl J Med 351:2599-610. 2004..Although plasma lipid levels were more strongly associated with an increased risk than were inflammatory markers, the level of C-reactive protein remained a significant contributor to the prediction of coronary heart disease... - Multivariate assessment of lipid parameters as predictors of coronary heart disease among postmenopausal women: potential implications for clinical guidelinesIris Shai
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Circulation 110:2824-30. 2004..Over the past decade, lipid measurements have been significantly improved and standardized. We evaluated the usefulness of multiple plasma lipid parameters in predicting coronary heart diseases (CHD) among women... - Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trialI Min Lee
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
JAMA 294:56-65. 2005..Randomized trials do not generally support benefits of vitamin E, but there are few trials of long duration among initially healthy persons... - Association between body mass index and CKD in apparently healthy menRebecca P Gelber
Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02120, USA
Am J Kidney Dis 46:871-80. 2005..06 to 1.53). CONCLUSION: In this large cohort of initially healthy men, BMI was associated significantly with increased risk for CKD after 14 years. Strategies to decrease CKD risk might include prevention of overweight and obesity... - Effect of combined folic acid, vitamin B(6), and vitamin B(12) on colorectal adenomaYiqing Song
Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
J Natl Cancer Inst 104:1562-75. 2012..Folic acid, vitamin B(6), and vitamin B(12) act in concert in the one-carbon metabolism and may protect against colorectal neoplasia. We examined the effect of combined B-vitamin treatment on the occurrence of colorectal adenoma... - The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular diseaseJoAnn E Manson
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, United States
Contemp Clin Trials 33:159-71. 2012.... - Dietary fat types and 4-year cognitive change in community-dwelling older womenOlivia I Okereke
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Ann Neurol 72:124-34. 2012..A study was undertaken to relate dietary fat types to cognitive change in healthy community-based elders... - Magnesium intake and risk of type 2 diabetes in men and womenRuy Lopez-Ridaura
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02215, USA
Diabetes Care 27:134-40. 2004..To examine the association between magnesium intake and risk of type 2 diabetes... - Blood pressure and risk of secondary cardiovascular events in women: the Women's Antioxidant Cardiovascular Study (WACS)Peter J Mason
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02215-1204, USA
Circulation 109:1623-9. 2004..CONCLUSIONS: In this population of women with CVD, we observed a strong, continuous, and linear association between SBP and risk of secondary CVD events. SBP was the blood pressure measure most strongly related to CVD risk... - Inflammatory markers and risk of developing type 2 diabetes in womenFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
Diabetes 53:693-700. 2004..001). These data support the role of inflammation in the pathogenesis of type 2 diabetes. Elevated CRP levels are a strong independent predictor of type 2 diabetes and may mediate associations of TNF-alphaR2 and IL-6 with type 2 diabetes... - Plasma homocysteine and cysteine and risk of breast cancer in womenJennifer Lin
Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA
Cancer Res 70:2397-405. 2010..The increased risk of breast cancer associated with high cysteine levels warrants further investigation... - Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged womenSimin Liu
Division of Preventive Medicine and the Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
Am J Clin Nutr 78:920-7. 2003..Although increased consumption of dietary fiber and grain products is widely recommended to maintain healthy body weight, little is known about the relation of whole grains to body weight and long-term weight changes... - The joint effects of physical activity and body mass index on coronary heart disease risk in womenAmy R Weinstein
Division of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Shapiro 1, Atrium Suite, Boston, MA 02215, USA
Arch Intern Med 168:884-90. 2008..Our objective was to study the combined association of physical activity and body mass index on CHD... - Low sex hormone-binding globulin is associated with the metabolic syndrome in postmenopausal womenMelissa E Weinberg
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
Metabolism 55:1473-80. 2006..7 kg/m2. An androgenic hormone profile is associated with both the individual components of the metabolic syndrome and clustering of metabolic abnormalities in postmenopausal women... - Total magnesium intake and colorectal cancer incidence in womenJennifer Lin
Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Cancer Epidemiol Biomarkers Prev 15:2006-9. 2006 - A prospective study of soluble tumor necrosis factor-alpha receptor II (sTNF-RII) and risk of coronary heart disease among women with type 2 diabetesIris Shai
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Diabetes Care 28:1376-82. 2005..Tumor necrosis factor-alpha (TNF-alpha), a cytokine secreted by adipose tissue and other cells, might play a role in insulin resistance... - Peroxisome proliferator-activated receptor-gamma2 P12A polymorphism and risk of coronary heart disease in US men and womenTobias Pischon
Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Mass, USA
Arterioscler Thromb Vasc Biol 25:1654-8. 2005..Studies suggest that the A12 allele is associated with reduced risk of type 2 diabetes; however, data on the risk of coronary heart disease (CHD) are scarce and controversial... - Adherence to a low-risk, healthy lifestyle and risk of sudden cardiac death among womenStephanie E Chiuve
Center for Arrhythmia Prevention, Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
JAMA 306:62-9. 2011..Primary preventive strategies are needed to reduce SCD incidence... - A prospective study of hemoglobin A1c concentrations and risk of breast cancer in womenJennifer Lin
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Cancer Res 66:2869-75. 2006..These data suggest that higher HbA1c concentrations do not seem to increase risk of breast cancer among apparently healthy women... - Dietary patterns, meat intake, and the risk of type 2 diabetes in womenTeresa T Fung
Department of Nutrition, Simmons College, Boston, Mass 02115, USA
Arch Intern Med 164:2235-40. 2004..To examine the association between major dietary patterns and risk of type 2 diabetes mellitus in a cohort of women... - The association between magnesium intake and fasting insulin concentration in healthy middle-aged womenTeresa T Fung
Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02215, USA
J Am Coll Nutr 22:533-8. 2003..We assessed the association between magnesium intake and fasting insulin levels in a large cohort of women... - Relation between markers of systemic vascular inflammation and smoking in womenEdmund A Bermudez
Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Boston, Massachusetts, USA
Am J Cardiol 89:1117-9. 2002 - Dietary magnesium intake in relation to plasma insulin levels and risk of type 2 diabetes in womenYiqing Song
Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
Diabetes Care 27:59-65. 2004..5 pmol/l among those at the highest quartile (P = 0.03 for trend). CONCLUSIONS: These findings support a protective role of higher intake of magnesium in reducing the risk of developing type 2 diabetes, especially in overweight women... - Dietary intake of whole and refined grain breakfast cereals and weight gain in menLydia A Bazzano
Department of Medicine, Beth Israel Deaconess Hospital, Boston, Massachusetts, USA
Obes Res 13:1952-60. 2005..78 and 0.88; 95% confidence interval, 0.67 to 0.91 and 0.76 to 1.00, respectively). DISCUSSION: BMI and weight gain were inversely associated with intake of breakfast cereals, independently of other risk factors... - Interrelationships among circulating interleukin-6, C-reactive protein, and traditional cardiovascular risk factors in womenEdmund A Bermudez
Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02215, USA
Arterioscler Thromb Vasc Biol 22:1668-73. 2002..Interleukin-6 (IL-6) and C-reactive protein (CRP) are markers of systemic vascular inflammation that herald atherothrombosis and may have important interrelationships with traditional cardiovascular risk factors... - Polymorphisms and haplotypes of the estrogen receptor-beta gene (ESR2) and cardiovascular disease in men and womenKathryn M Rexrode
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Clin Chem 53:1749-56. 2007..Cohort studies suggest an association between variation in the estrogen receptor-alpha gene (ESR1) and cardiovascular disease (CVD), but data are lacking for the effect of variation in the estrogen receptor-beta gene (ESR2)... - Low-carbohydrate-diet score and risk of type 2 diabetes in womenThomas L Halton
Department of Nutrition, Harvard School of Public Health, Boston, MA 02215, USA
Am J Clin Nutr 87:339-46. 2008..Low-carbohydrate weight-loss diets remain popular; however, the long-term effects of these diets are not known... - A prospective study of sugar intake and risk of type 2 diabetes in womenSok-Ja Janket
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA
Diabetes Care 26:1008-15. 2003..These prospective data support the recent American Diabetes Association's guideline that a moderate amount of sugar can be incorporated in a healthy diet... - Chronic obstructive pulmonary disease, asthma, and risk of type 2 diabetes in womenJamal S Rana
Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
Diabetes Care 27:2478-84. 2004..Differences in the inflammation and cytokine profile between COPD and asthma might explain why COPD, but not asthma, is associated with increased risk of type 2 diabetes... - A prospective study of red meat consumption and type 2 diabetes in middle-aged and elderly women: the women's health studyYiqing Song
Division of Preventive Medicine, Department of Medicine, BrighamWomen's Hospital, Harvard Medical School, 900 Commonwealth Ave. East, Boston, MA 02215, USA
Diabetes Care 27:2108-15. 2004..CONCLUSIONS: Our data indicate that higher consumption of total red meat, especially various processed meats, may increase risk of developing type 2 diabetes in women... - Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitusJames B Meigs
General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
JAMA 291:1978-86. 2004..Endothelial dysfunction occurs in diagnosed type 2 diabetes mellitus but may also precede development of diabetes... - A prospective study of multivitamin supplement use and risk of breast cancerKen Ishitani
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
Am J Epidemiol 167:1197-206. 2008.... - Measures of obesity and cardiovascular risk among men and womenRebecca P Gelber
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
J Am Coll Cardiol 52:605-15. 2008.... - Effects of estrogen plus progestin on health-related quality of lifeJennifer Hays
Center for Women s Health, Department of Medicine, Baylor College of Medicine, Houston 77025, USA
N Engl J Med 348:1839-54. 2003..The Women's Health Initiative (WHI) and other clinical trials indicate that significant health risks are associated with combination hormone use. Less is known about the effect of hormone therapy on health-related quality of life... - Common variants in cardiac ion channel genes are associated with sudden cardiac deathChristine M Albert
Center for Arrhythmia Prevention, Division of Preventive Medicine, Cardiovascular Division, Channing Laboratory, and Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115 1204, USA
Circ Arrhythm Electrophysiol 3:222-9. 2010.... - Alcohol drinking patterns and risk of type 2 diabetes mellitus among younger womenS Goya Wannamethee
Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
Arch Intern Med 163:1329-36. 2003..To examine the relationship between alcohol consumption and the incidence of type 2 diabetes mellitus among relatively young and middle-aged women... - Postmenopausal hormone therapy: new questions and the case for new clinical trialsJoAnn E Manson
Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
Menopause 13:139-47. 2006.... - Kidney dysfunction, inflammation, and coronary events: a prospective studyEric L Knight
Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Soc Nephrol 15:1897-903. 2004..These findings warrant further investigation in other populations... - Dietary calcium, vitamin D, and the prevalence of metabolic syndrome in middle-aged and older U.S. womenSimin Liu
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Diabetes Care 28:2926-32. 2005..To examine whether and to what extent intakes of calcium and vitamin D are related to the metabolic syndrome in middle-aged or older women... - Hemoglobin A1c level and future cardiovascular events among womenGavin J Blake
Cardiovascular Division, The Center for Cardiovascular Disease Prevention, and the Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
Arch Intern Med 164:757-61. 2004..We sought to test this hypothesis prospectively in a cohort of women without overt cardiovascular disease... - Adiposity compared with physical inactivity and risk of type 2 diabetes in womenJamal S Rana
Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Diabetes Care 30:53-8. 2007..The relative contribution of adiposity and physical inactivity to the risk of developing type 2 diabetes remains controversial... - Long-chain omega-3 fatty acids, fish intake, and the risk of type 2 diabetes mellitusManas Kaushik
Departments of Nutrition, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
Am J Clin Nutr 90:613-20. 2009..The role of long-chain omega-3 (n-3) fatty acids (LCFAs) in the development of T2DM remains unresolved. Objective: We examined the association between dietary LCFAs and incidence of T2DM in 3 prospective cohorts of women and men... - Biomarkers of inflammation and development of rheumatoid arthritis in women from two prospective cohort studiesElizabeth W Karlson
Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Arthritis Rheum 60:641-52. 2009..To examine the association of biomarkers of inflammation with preclinical rheumatoid arthritis (RA)... - Is C-reactive protein specific for vascular disease in women?Nader Rifai
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
Ann Intern Med 136:529-33. 2002..C-reactive protein (CRP) predicts risk for future cardiovascular events in asymptomatic individuals. However, because CRP also predicts total mortality, its specificity for vascular disease is uncertain... - Inflammation and progressive nephropathy in type 1 diabetes in the diabetes control and complications trialJulie Lin
Renal Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes Care 31:2338-43. 2008..Early albuminuria probably reflects vascular endothelial dysfunction, which may be mediated in part by chronic inflammation... - Nut consumption and decreased risk of sudden cardiac death in the Physicians' Health StudyChristine M Albert
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215 1204, USA
Arch Intern Med 162:1382-7. 2002..Since components of nuts may have antiarrhythmic properties, part of the benefit may be due to a reduction in sudden cardiac death... - Inflammatory biomarkers, hormone replacement therapy, and incident coronary heart disease: prospective analysis from the Women's Health Initiative observational studyAruna D Pradhan
Center for Cardiovascular Disease Prevention, Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02215-1204, USA
JAMA 288:980-7. 2002..However, use or nonuse of HRT had less importance as a predictor of cardiovascular risk than did baseline levels of either CRP or IL-6... - Coffee consumption and risk for type 2 diabetes mellitusEduardo Salazar-Martinez
Harvard School of Public Health, Channing Laboratory, Harvard Medical School, and Brigham and Women's Hospital, Boston, Massachusetts 02215, USA
Ann Intern Med 140:1-8. 2004..CONCLUSIONS: These data suggest that long-term coffee consumption is associated with a statistically significantly lower risk for type 2 diabetes... - A prospective study of serum lipids and risk of diabetic macular edema in type 1 diabetesBiljana Miljanovic
Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Ave. East, Boston, MA 02215, USA
Diabetes 53:2883-92. 2004..Lipid-lowering treatment among type 1 diabetic subjects, recommended to prevent cardiovascular disease, may also decrease risk of CSME, an important cause of vision loss... - Body mass index and mortality among US male physiciansUmed A Ajani
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
Ann Epidemiol 14:731-9. 2004..Advancing age did not attenuate the increased risk of death associated with obesity. Lean men (BMI<20) did not have excess mortality, regardless of age... - Potato and french fry consumption and risk of type 2 diabetes in womenThomas L Halton
Department of Nutrition and Epidemiology, Department of Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02215, USA
Am J Clin Nutr 83:284-90. 2006..CONCLUSIONS: Our findings suggest a modest positive association between the consumption of potatoes and the risk of type 2 diabetes in women. This association was more pronounced when potatoes were substituted for whole grains... - A prospective study of dairy intake and the risk of type 2 diabetes in womenSimin Liu
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Diabetes Care 29:1579-84. 2006..Although studies have indicated that increased dairy intake may reduce risk of overweight and insulin resistance syndrome, data directly relating dairy intake to type 2 diabetes remain sparse...