JoAnn E Manson

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint The escalating pandemics of obesity and sedentary lifestyle. A call to action for clinicians
    JoAnn E Manson
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Arch Intern Med 164:249-58. 2004
  2. pmc Increased mortality risk in women with depression and diabetes mellitus
    An Pan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Gen Psychiatry 68:42-50. 2011
  3. pmc Age-related cataract in a randomized trial of vitamins E and C in men
    William G Christen
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215 1204, USA
    Arch Ophthalmol 128:1397-405. 2010
  4. pmc FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 16:2472-80. 2008
  5. pmc Vitamins C and E and beta carotene supplementation and cancer risk: a randomized controlled trial
    Jennifer Lin
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215, USA
    J Natl Cancer Inst 101:14-23. 2009
  6. ncbi request reprint Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women
    Jennifer Lin
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 87:734-43. 2008
  7. ncbi request reprint Alcohol consumption and breast cancer risk in the Women's Health Study
    Shumin M Zhang
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Am J Epidemiol 165:667-76. 2007
  8. pmc Hyperglycemia, insulin resistance, impaired pancreatic β-cell function, and risk of pancreatic cancer
    Brian M Wolpin
    Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02215, USA
    J Natl Cancer Inst 105:1027-35. 2013
  9. pmc Red meat consumption and mortality: results from 2 prospective cohort studies
    An Pan
    Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Intern Med 172:555-63. 2012
  10. ncbi request reprint Phobic anxiety and risk of coronary heart disease and sudden cardiac death among women
    Christine M Albert
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215 1204, USA
    Circulation 111:480-7. 2005

Collaborators

Detail Information

Publications125 found, 100 shown here

  1. ncbi request reprint The escalating pandemics of obesity and sedentary lifestyle. A call to action for clinicians
    JoAnn E Manson
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Arch Intern Med 164:249-58. 2004
    ..This blueprint for action, which requires only a few minutes of a clinician's time to implement, will facilitate more effective intervention related to obesity and inactivity and should favorably impact public health...
  2. pmc Increased mortality risk in women with depression and diabetes mellitus
    An Pan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Gen Psychiatry 68:42-50. 2011
    ..Depression and diabetes mellitus have been associated with an increased risk of all-cause and cardiovascular disease (CVD) mortality. However, data evaluating the joint effects of these 2 conditions on mortality are sparse...
  3. pmc Age-related cataract in a randomized trial of vitamins E and C in men
    William G Christen
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215 1204, USA
    Arch Ophthalmol 128:1397-405. 2010
    ..To test whether supplementation with alternate-day vitamin E or daily vitamin C affects the incidence of age-related cataract in a large cohort of men...
  4. pmc FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 16:2472-80. 2008
    ..In conclusion, common genetic variants in the intron 1 of FTO gene may confer a modest susceptibility to obesity in an ethnicity-specific manner, but may be unlikely to contribute to a clinically significant diabetes risk...
  5. pmc Vitamins C and E and beta carotene supplementation and cancer risk: a randomized controlled trial
    Jennifer Lin
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215, USA
    J Natl Cancer Inst 101:14-23. 2009
    ..However, findings from randomized trials of the association between antioxidant use and cancer risk have been mostly negative...
  6. ncbi request reprint Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women
    Jennifer Lin
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 87:734-43. 2008
    ..B vitamins such as folate, vitamin B-6, and vitamin B-12 are coenzymes that are important for DNA integrity and stability. Deficiency in these B vitamins may promote tumor carcinogenesis...
  7. ncbi request reprint Alcohol consumption and breast cancer risk in the Women's Health Study
    Shumin M Zhang
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Am J Epidemiol 165:667-76. 2007
    ..The findings from this prospective study suggest that moderate alcohol consumption increases breast cancer risk...
  8. pmc Hyperglycemia, insulin resistance, impaired pancreatic β-cell function, and risk of pancreatic cancer
    Brian M Wolpin
    Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02215, USA
    J Natl Cancer Inst 105:1027-35. 2013
    ..Hemoglobin A1c (HbA1c) is a measure of hyperglycemia, whereas plasma insulin and proinsulin are markers of peripheral insulin resistance, and the proinsulin to insulin ratio marks pancreatic β-cell dysfunction...
  9. pmc Red meat consumption and mortality: results from 2 prospective cohort studies
    An Pan
    Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Intern Med 172:555-63. 2012
    ..Red meat consumption has been associated with an increased risk of chronic diseases. However, its relationship with mortality remains uncertain...
  10. ncbi request reprint Phobic anxiety and risk of coronary heart disease and sudden cardiac death among women
    Christine M Albert
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215 1204, USA
    Circulation 111:480-7. 2005
    ..To the best of our knowledge, no studies have looked at this association among women. Anxiety may influence CHD mortality by increasing the risk of ventricular arrhythmia and SCD...
  11. pmc Dietary glycemic index, dietary glycemic load, blood lipids, and C-reactive protein
    Emily B Levitan
    Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Metabolism 57:437-43. 2008
    ..24, and TG = 13 mg/dL). Differences in blood lipids and CRP between extreme quintiles of dietary GI and GL were small, but may translate into a clinically meaningful difference in cardiovascular risk...
  12. ncbi request reprint Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction
    Esther Lopez-Garcia
    Department of Nutrition and the Division of Preventive Medicine, Harvard Medical School, Boston, USA
    Am J Clin Nutr 80:1029-35. 2004
    ..Endothelial dysfunction is one of the mechanisms linking diet and the risk of cardiovascular disease...
  13. ncbi request reprint Consumption of trans fatty acids is related to plasma biomarkers of inflammation and endothelial dysfunction
    Esther Lopez-Garcia
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Nutr 135:562-6. 2005
    ....
  14. pmc Vitamins E and C and medical record-confirmed age-related macular degeneration in a randomized trial of male physicians
    William G Christen
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Ophthalmology 119:1642-9. 2012
    ..To test whether supplementation with alternate-day vitamin E or daily vitamin C affects the incidence of the diagnosis of age-related macular degeneration (AMD) in a large-scale randomized trial of male physicians...
  15. ncbi request reprint Single nucleotide polymorphisms at the adiponectin locus and risk of coronary heart disease in men and women
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 15:2051-60. 2007
    ..The objective was to examine the association of 5 common single nucleotide polymorphisms (SNPs) at the adiponectin locus with risk of coronary heart disease (CHD) in men and women...
  16. pmc Sex hormone-binding globulin and risk of type 2 diabetes in women and men
    Eric L Ding
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    N Engl J Med 361:1152-63. 2009
    ..Circulating sex hormone-binding globulin levels are inversely associated with insulin resistance, but whether these levels can predict the risk of developing type 2 diabetes is uncertain...
  17. pmc Effects of vitamins C and E and beta-carotene on the risk of type 2 diabetes in women at high risk of cardiovascular disease: a randomized controlled trial
    Yiqing Song
    Division of Preventive Medicine and Cardiology Division, Harvard School of Public Health, Boston, MA 02215, USA
    Am J Clin Nutr 90:429-37. 2009
    ..Vitamin C, vitamin E, and beta-carotene are major antioxidants and as such may protect against the development of type 2 diabetes via reduction of oxidative stress...
  18. pmc Sweetened beverage consumption and risk of coronary heart disease in women
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, MA 02115, USA
    Am J Clin Nutr 89:1037-42. 2009
    ..Previous studies have linked full-calorie sugar-sweetened beverages (SSBs) with greater weight gain and an increased risk of type 2 diabetes...
  19. ncbi request reprint Sex hormone-binding globulin and serum testosterone are inversely associated with C-reactive protein levels in postmenopausal women at high risk for cardiovascular disease
    Hylton V Joffe
    Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women s Hospital, 221 Longwood Ave, Boston, MA 02215, USA
    Ann Epidemiol 16:105-12. 2006
    ..We hypothesized that high androgens, low estradiol, and low sex hormone-binding globulin (SHBG) would be associated with high CRP in postmenopausal women...
  20. pmc Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial
    J Michael Gaziano
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
    JAMA 301:52-62. 2009
    ..No previous trial in men at usual risk has examined vitamin C alone in the prevention of cancer...
  21. pmc Plasma vitamin B(6) and risk of myocardial infarction in women
    John H Page
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Circulation 120:649-55. 2009
    ..We prospectively evaluated the relationships between fasting plasma levels of vitamin B(6), as pyridoxal phosphate, and subsequent myocardial infarction risk in women...
  22. pmc Genetic variation in sex-steroid receptors and synthesizing enzymes and colorectal cancer risk in women
    Jennifer Lin
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Cancer Causes Control 21:897-908. 2010
    ....
  23. ncbi request reprint Magnesium intake and plasma concentrations of markers of systemic inflammation and endothelial dysfunction in women
    Yiqing Song
    Division of Preventive Medicine and Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 85:1068-74. 2007
    ..Relations between magnesium intake and systemic inflammation and endothelial dysfunction are not well established...
  24. ncbi request reprint Vitamin C and risk of coronary heart disease in women
    Stavroula K Osganian
    Department of Medicine, Children s Hospital, Boston, Massachusetts, USA
    J Am Coll Cardiol 42:246-52. 2003
    ..Our objective was to prospectively examine the relation between vitamin C intake and risk of coronary heart disease (CHD) in women...
  25. ncbi request reprint C-reactive protein is independently associated with fasting insulin in nondiabetic women
    Aruna D Pradhan
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, Mass 02215 1204, USA
    Arterioscler Thromb Vasc Biol 23:650-5. 2003
    ..Insulin resistance is associated with chronic subclinical inflammation, and both conditions are linked with increased risk for type 2 diabetes mellitus and atherothrombotic cardiovascular disease...
  26. pmc Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials
    JoAnn E Manson
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    JAMA 310:1353-68. 2013
    ..Menopausal hormone therapy continues in clinical use but questions remain regarding its risks and benefits for chronic disease prevention...
  27. pmc Sex hormone levels and risk of breast cancer with estrogen plus progestin
    Ghada N Farhat
    Affiliations of authors San Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, CA GNF, NP, SRC Faculty of Health Sciences, University of Balamand, Beirut, Lebanon GNF Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA RTC Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA JEM Fred Hutchinson Cancer Research Center, Seattle, WA GA, AZL Department of Internal Medicine, University of California San Francisco, San Francisco, CA AH, DG Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA EV Department of Internal Medicine, University of California Davis, Sacramento, CA JSL Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA JAC Department of Internal Medicine, Ohio State University, Columbus, OH RJ Department of Preventive Medicine, Stony Brook University, Stony Brook, NY DL Department of Medicine, Emory University, Atlanta, GA LP Karmanos Cancer Institute, Wayne State University, Detroit, MI MSS
    J Natl Cancer Inst 105:1496-503. 2013
    ..Although high endogenous sex hormone levels and estrogen plus progestin (E+P) therapy are associated with increased breast cancer risk, it is unknown whether pretreatment levels of sex hormones modify E+P effect on breast cancer...
  28. pmc Beta carotene supplementation and age-related maculopathy in a randomized trial of US physicians
    William G Christen
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215 1204, USA
    Arch Ophthalmol 125:333-9. 2007
    ..To test whether beta carotene supplementation affects the incidence of age-related maculopathy (ARM) in a large-scale randomized trial...
  29. ncbi request reprint A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women
    Paul M Ridker
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, USA
    N Engl J Med 352:1293-304. 2005
    ..Randomized trials have shown that low-dose aspirin decreases the risk of a first myocardial infarction in men, with little effect on the risk of ischemic stroke. There are few similar data in women...
  30. pmc Bidirectional association between depression and type 2 diabetes mellitus in women
    An Pan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Intern Med 170:1884-91. 2010
    ..Although it has been hypothesized that the diabetes-depression relation is bidirectional, few studies have addressed this hypothesis in a prospective setting...
  31. pmc Effect of homocysteine-lowering treatment with folic Acid and B vitamins on risk of type 2 diabetes in women: a randomized, controlled trial
    Yiqing Song
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 58:1921-8. 2009
    ..We investigated whether homocysteine-lowering treatment by B vitamin supplementation prevents the risk of type 2 diabetes...
  32. ncbi request reprint Low-carbohydrate-diet score and the risk of coronary heart disease in women
    Thomas L Halton
    Departments of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 355:1991-2002. 2006
    ..Low-carbohydrate diets have been advocated for weight loss and to prevent obesity, but the long-term safety of these diets has not been determined...
  33. ncbi request reprint Sexual orientation, health risk factors, and physical functioning in the Nurses' Health Study II
    Patricia Case
    Department of Social Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Womens Health (Larchmt) 13:1033-47. 2004
    ..To examine associations between sexual orientation and breast cancer risk factors, cardiovascular disease (CVD) risk factors, mental health status, and health-related functioning...
  34. pmc Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial
    Howard D Sesso
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
    JAMA 300:2123-33. 2008
    ..However, few long-term trials have evaluated men at initially low risk of cardiovascular disease, and no previous trial in men has examined vitamin C alone in the prevention of cardiovascular disease...
  35. ncbi request reprint Adherence to the Mediterranean dietary pattern is positively associated with plasma adiponectin concentrations in diabetic women
    Christos S Mantzoros
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA and Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 84:328-35. 2006
    ....
  36. pmc Obesity as compared with physical activity in predicting risk of coronary heart disease in women
    Tricia Y Li
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 113:499-506. 2006
    ..The comparative importance of physical inactivity and obesity as predictors of coronary heart disease (CHD) risk remains unsettled...
  37. pmc Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of women
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 56:1898-904. 2007
    ..S. postmenopausal women, implicating an etiological role of endothelial dysfunction in the pathogenesis of type 2 diabetes...
  38. pmc Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trial
    Christine M Albert
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, Massachusetts 02215 1204, USA
    JAMA 299:2027-36. 2008
    ..Observational data suggest benefits may be greater among women, yet women have been underrepresented in published randomized trials...
  39. pmc Eight-year change in body mass index and subsequent risk of cardiovascular disease among healthy non-smoking men
    Thomas S Bowman
    VA Boston Healthcare System Massachusetts Veterans Affairs Epidemiology, Research, and Information Center MAVERIC, Boston, MA, USA
    Prev Med 45:436-41. 2007
    ..To determine how change in BMI over 8 years is associated with risk of subsequent cardiovascular disease (CVD) among middle aged men...
  40. ncbi request reprint Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women
    Yiqing Song
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Diabetes Care 28:1438-44. 2005
    ..The aim of this study was to examine whether and to what extent magnesium intake is related to systemic inflammation and the metabolic syndrome...
  41. ncbi request reprint Prospective study of major dietary patterns and stroke risk in women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02115, USA
    Stroke 35:2014-9. 2004
    ..Many foods have been suggested to influence the risk of stroke. However, no previous studies have examined the relationship between overall dietary patterns and risk of stroke...
  42. pmc Effect of combined folic acid, vitamin B6, and vitamin B12 on cancer risk in women: a randomized trial
    Shumin M Zhang
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    JAMA 300:2012-21. 2008
    ..Folate, vitamin B(6), and vitamin B(12) are thought to play an important role in cancer prevention...
  43. pmc Effects of multivitamin supplement on cataract and age-related macular degeneration in a randomized trial of male physicians
    William G Christen
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts Electronic address
    Ophthalmology 121:525-34. 2014
    ..To test whether long-term multivitamin supplementation affects the incidence of cataract or age-related macular degeneration (AMD) in a large cohort of men...
  44. pmc Quantity and variety in fruit and vegetable intake and risk of coronary heart disease
    Shilpa N Bhupathiraju
    Department of Nutrition, Harvard School of Public Health, Boston, MA SNB, NMW, WCW, and FBH Saw Swee Hock School of Public Health and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore AP the Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA JEM and KMR the Department of Epidemiology, Harvard School of Public Health, Boston, MA JEM, WCW, EBR, and FBH and the Channing Division of Network Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA WCW, EBR, and FBH
    Am J Clin Nutr 98:1514-23. 2013
    ..Dietary guidelines recommend increasing fruit and vegetable intake and, most recently, have also suggested increasing variety...
  45. pmc Caffeinated and caffeine-free beverages and risk of type 2 diabetes
    Shilpa N Bhupathiraju
    Departments of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 97:155-66. 2013
    ..Consumption of caffeinated beverages such as coffee and tea has been associated with a lower risk of type 2 diabetes (T2D). Paradoxically, short-term metabolic studies have shown that caffeine impairs postprandial glycemic control...
  46. pmc Plasma adiponectin and the risk of hypertension in white and black postmenopausal women
    Lu Wang
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Clin Chem 58:1438-45. 2012
    ..We conducted a prospective, nested case control study to investigate the relation between baseline plasma adiponectin, measures of adiposity, and subsequent risk of hypertension...
  47. ncbi request reprint Conjugated equine estrogens and coronary heart disease: the Women's Health Initiative
    Judith Hsia
    Department of Medicine, George Washington University, Washington, DC, USA
    Arch Intern Med 166:357-65. 2006
    ..These trials did not address the role of unopposed estrogen for coronary protection...
  48. ncbi request reprint Carbohydrate intake, glycemic index, glycemic load, and dietary fiber in relation to risk of stroke in women
    Kyungwon Oh
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 161:161-9. 2005
    ..In addition, high consumption of cereal fiber was associated with lower risk of total and hemorrhagic stroke...
  49. ncbi request reprint Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetes
    Asli Memisoglu
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Diabetes Care 26:2915-7. 2003
    ..To determine whether the Pro12Ala polymorphism in the PPARgamma gene was associated with risk of type 2 diabetes in the Nurses' Health Study...
  50. ncbi request reprint Plasma lycopene, other carotenoids, and the risk of type 2 diabetes in women
    Lu Wang
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Am J Epidemiol 164:576-85. 2006
    ..91 (95% CI: 0.46, 1.81) for beta-cryptoxanthin, and 1.35 (95% CI: 0.68, 2.69) for lutein/zeaxanthin. There was no prospective association between baseline plasma carotenoids and the risk of type 2 diabetes in middle-aged and older women...
  51. ncbi request reprint A prospective study of trans fatty acids in erythrocytes and risk of coronary heart disease
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 115:1858-65. 2007
    ..We assessed the hypothesis that higher trans fatty acid contents in erythrocytes were associated with an elevated risk of CHD in a nested case-control study among US women...
  52. pmc Major dietary protein sources and risk of coronary heart disease in women
    Adam M Bernstein
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 122:876-83. 2010
    ..Our objective was to examine the relation between foods that are major dietary protein sources and incident CHD...
  53. ncbi request reprint Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial
    I Min Lee
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    JAMA 294:56-65. 2005
    ..Randomized trials do not generally support benefits of vitamin E, but there are few trials of long duration among initially healthy persons...
  54. pmc Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in women
    Yiqing Song
    Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMC Med Genet 10:4. 2009
    ..However, it is unclear whether common genetic variation in TRPM6 and TRPM7 contributes to risk of type 2 diabetes...
  55. ncbi request reprint Association between body mass index and CKD in apparently healthy men
    Rebecca P Gelber
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Am J Kidney Dis 46:871-80. 2005
    ..Conversely, their association with the development of CKD is less clear...
  56. ncbi request reprint Inflammatory markers and the risk of coronary heart disease in men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:2599-610. 2004
    ..The value of these inflammatory markers as independent predictors remains controversial...
  57. ncbi request reprint Multivariate assessment of lipid parameters as predictors of coronary heart disease among postmenopausal women: potential implications for clinical guidelines
    Iris Shai
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 110:2824-30. 2004
    ..Over the past decade, lipid measurements have been significantly improved and standardized. We evaluated the usefulness of multiple plasma lipid parameters in predicting coronary heart diseases (CHD) among women...
  58. pmc Alcohol consumption, weight gain, and risk of becoming overweight in middle-aged and older women
    Lu Wang
    Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Arch Intern Med 170:453-61. 2010
    ..Alcohol consumption is a source of energy intake that may contribute to body weight gain and development of obesity. However, previous studies of this relationship have been limited, with inconsistent results...
  59. pmc Calcium/vitamin D supplementation and coronary artery calcification in the Women's Health Initiative
    JoAnn E Manson
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Menopause 17:683-91. 2010
    ..We compared CAC scores after trial completion between women randomized to calcium/vitamin D supplementation and women randomized to placebo...
  60. pmc Effect of combined folic acid, vitamin B(6), and vitamin B(12) on colorectal adenoma
    Yiqing Song
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    J Natl Cancer Inst 104:1562-75. 2012
    ..Folic acid, vitamin B(6), and vitamin B(12) act in concert in the one-carbon metabolism and may protect against colorectal neoplasia. We examined the effect of combined B-vitamin treatment on the occurrence of colorectal adenoma...
  61. pmc The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease
    JoAnn E Manson
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, United States
    Contemp Clin Trials 33:159-71. 2012
    ....
  62. pmc Dietary fat types and 4-year cognitive change in community-dwelling older women
    Olivia I Okereke
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Ann Neurol 72:124-34. 2012
    ..A study was undertaken to relate dietary fat types to cognitive change in healthy community-based elders...
  63. pmc Adherence to a low-risk, healthy lifestyle and risk of sudden cardiac death among women
    Stephanie E Chiuve
    Center for Arrhythmia Prevention, Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    JAMA 306:62-9. 2011
    ..Primary preventive strategies are needed to reduce SCD incidence...
  64. pmc Plasma homocysteine and cysteine and risk of breast cancer in women
    Jennifer Lin
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA
    Cancer Res 70:2397-405. 2010
    ..The increased risk of breast cancer associated with high cysteine levels warrants further investigation...
  65. doi request reprint The joint effects of physical activity and body mass index on coronary heart disease risk in women
    Amy R Weinstein
    Division of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Shapiro 1, Atrium Suite, Boston, MA 02215, USA
    Arch Intern Med 168:884-90. 2008
    ..Our objective was to study the combined association of physical activity and body mass index on CHD...
  66. ncbi request reprint Inflammatory markers and risk of developing type 2 diabetes in women
    Frank B Hu
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes 53:693-700. 2004
    ..001). These data support the role of inflammation in the pathogenesis of type 2 diabetes. Elevated CRP levels are a strong independent predictor of type 2 diabetes and may mediate associations of TNF-alphaR2 and IL-6 with type 2 diabetes...
  67. ncbi request reprint A prospective study of hemoglobin A1c concentrations and risk of breast cancer in women
    Jennifer Lin
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Cancer Res 66:2869-75. 2006
    ..These data suggest that higher HbA1c concentrations do not seem to increase risk of breast cancer among apparently healthy women...
  68. ncbi request reprint Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women
    Simin Liu
    Division of Preventive Medicine and the Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 78:920-7. 2003
    ..Although increased consumption of dietary fiber and grain products is widely recommended to maintain healthy body weight, little is known about the relation of whole grains to body weight and long-term weight changes...
  69. ncbi request reprint Blood pressure and risk of secondary cardiovascular events in women: the Women's Antioxidant Cardiovascular Study (WACS)
    Peter J Mason
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02215 1204, USA
    Circulation 109:1623-9. 2004
    ..In apparently healthy people, the relation between blood pressure and risk of subsequent cardiovascular disease (CVD) is linear. In persons with CVD, the relation is uncertain...
  70. ncbi request reprint Dietary patterns, meat intake, and the risk of type 2 diabetes in women
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, Mass 02115, USA
    Arch Intern Med 164:2235-40. 2004
    ..To examine the association between major dietary patterns and risk of type 2 diabetes mellitus in a cohort of women...
  71. ncbi request reprint Peroxisome proliferator-activated receptor-gamma2 P12A polymorphism and risk of coronary heart disease in US men and women
    Tobias Pischon
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    Arterioscler Thromb Vasc Biol 25:1654-8. 2005
    ..Studies suggest that the A12 allele is associated with reduced risk of type 2 diabetes; however, data on the risk of coronary heart disease (CHD) are scarce and controversial...
  72. ncbi request reprint Total magnesium intake and colorectal cancer incidence in women
    Jennifer Lin
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Cancer Epidemiol Biomarkers Prev 15:2006-9. 2006
  73. ncbi request reprint Magnesium intake and risk of type 2 diabetes in men and women
    Ruy Lopez-Ridaura
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02215, USA
    Diabetes Care 27:134-40. 2004
    ..To examine the association between magnesium intake and risk of type 2 diabetes...
  74. pmc Low sex hormone-binding globulin is associated with the metabolic syndrome in postmenopausal women
    Melissa E Weinberg
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Metabolism 55:1473-80. 2006
    ..7 kg/m2. An androgenic hormone profile is associated with both the individual components of the metabolic syndrome and clustering of metabolic abnormalities in postmenopausal women...
  75. ncbi request reprint A prospective study of soluble tumor necrosis factor-alpha receptor II (sTNF-RII) and risk of coronary heart disease among women with type 2 diabetes
    Iris Shai
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Diabetes Care 28:1376-82. 2005
    ..Tumor necrosis factor-alpha (TNF-alpha), a cytokine secreted by adipose tissue and other cells, might play a role in insulin resistance...
  76. ncbi request reprint The association between magnesium intake and fasting insulin concentration in healthy middle-aged women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02215, USA
    J Am Coll Nutr 22:533-8. 2003
    ..We assessed the association between magnesium intake and fasting insulin levels in a large cohort of women...
  77. ncbi request reprint Interrelationships among circulating interleukin-6, C-reactive protein, and traditional cardiovascular risk factors in women
    Edmund A Bermudez
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02215, USA
    Arterioscler Thromb Vasc Biol 22:1668-73. 2002
    ..Interleukin-6 (IL-6) and C-reactive protein (CRP) are markers of systemic vascular inflammation that herald atherothrombosis and may have important interrelationships with traditional cardiovascular risk factors...
  78. ncbi request reprint Relation between markers of systemic vascular inflammation and smoking in women
    Edmund A Bermudez
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Cardiol 89:1117-9. 2002
  79. ncbi request reprint Dietary intake of whole and refined grain breakfast cereals and weight gain in men
    Lydia A Bazzano
    Department of Medicine, Beth Israel Deaconess Hospital, Boston, Massachusetts, USA
    Obes Res 13:1952-60. 2005
    ..The aim of this study was to prospectively assess the association between whole and refined grain breakfast cereal intakes and risk of overweight (BMI >or= 25 kg/m(2)) and weight gain...
  80. ncbi request reprint Dietary magnesium intake in relation to plasma insulin levels and risk of type 2 diabetes in women
    Yiqing Song
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Diabetes Care 27:59-65. 2004
    ..Higher intake of magnesium appears to improve glucose and insulin homeostasis; however, there are sparse prospective data on the association between magnesium intake and incidence of type 2 diabetes...
  81. pmc Polymorphisms and haplotypes of the estrogen receptor-beta gene (ESR2) and cardiovascular disease in men and women
    Kathryn M Rexrode
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin Chem 53:1749-56. 2007
    ..Cohort studies suggest an association between variation in the estrogen receptor-alpha gene (ESR1) and cardiovascular disease (CVD), but data are lacking for the effect of variation in the estrogen receptor-beta gene (ESR2)...
  82. ncbi request reprint Chronic obstructive pulmonary disease, asthma, and risk of type 2 diabetes in women
    Jamal S Rana
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Diabetes Care 27:2478-84. 2004
    ..Increasing evidence points toward a role of inflammation in the pathogenesis of type 2 diabetes. We wanted to determine the relation of COPD and asthma with the development of type 2 diabetes...
  83. ncbi request reprint A prospective study of red meat consumption and type 2 diabetes in middle-aged and elderly women: the women's health study
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, BrighamWomen s Hospital, Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215, USA
    Diabetes Care 27:2108-15. 2004
    ..The aim of this study was to prospectively assess the relation between red meat intake and incidence of type 2 diabetes...
  84. ncbi request reprint Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus
    James B Meigs
    General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    JAMA 291:1978-86. 2004
    ..Endothelial dysfunction occurs in diagnosed type 2 diabetes mellitus but may also precede development of diabetes...
  85. doi request reprint A prospective study of multivitamin supplement use and risk of breast cancer
    Ken Ishitani
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Epidemiol 167:1197-206. 2008
    ....
  86. pmc Low-carbohydrate-diet score and risk of type 2 diabetes in women
    Thomas L Halton
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02215, USA
    Am J Clin Nutr 87:339-46. 2008
    ..Low-carbohydrate weight-loss diets remain popular; however, the long-term effects of these diets are not known...
  87. ncbi request reprint A prospective study of sugar intake and risk of type 2 diabetes in women
    Sok Ja Janket
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 26:1008-15. 2003
    ..The contribution of sugar intake to the pathogenesis of type 2 diabetes has not been settled in the context of primary prevention because of limited prospective data...
  88. ncbi request reprint Hemoglobin A1c level and future cardiovascular events among women
    Gavin J Blake
    Cardiovascular Division, The Center for Cardiovascular Disease Prevention, and the Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Arch Intern Med 164:757-61. 2004
    ..We sought to test this hypothesis prospectively in a cohort of women without overt cardiovascular disease...
  89. pmc Common variants in cardiac ion channel genes are associated with sudden cardiac death
    Christine M Albert
    Center for Arrhythmia Prevention, Division of Preventive Medicine, Cardiovascular Division, Channing Laboratory, and Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115 1204, USA
    Circ Arrhythm Electrophysiol 3:222-9. 2010
    ....
  90. ncbi request reprint Kidney dysfunction, inflammation, and coronary events: a prospective study
    Eric L Knight
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Nephrol 15:1897-903. 2004
    ..These findings warrant further investigation in other populations...
  91. ncbi request reprint Alcohol drinking patterns and risk of type 2 diabetes mellitus among younger women
    S Goya Wannamethee
    Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
    Arch Intern Med 163:1329-36. 2003
    ..To examine the relationship between alcohol consumption and the incidence of type 2 diabetes mellitus among relatively young and middle-aged women...
  92. ncbi request reprint Effects of estrogen plus progestin on health-related quality of life
    Jennifer Hays
    Center for Women s Health, Department of Medicine, Baylor College of Medicine, Houston 77025, USA
    N Engl J Med 348:1839-54. 2003
    ..The Women's Health Initiative (WHI) and other clinical trials indicate that significant health risks are associated with combination hormone use. Less is known about the effect of hormone therapy on health-related quality of life...
  93. ncbi request reprint Adiposity compared with physical inactivity and risk of type 2 diabetes in women
    Jamal S Rana
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Diabetes Care 30:53-8. 2007
    ..The relative contribution of adiposity and physical inactivity to the risk of developing type 2 diabetes remains controversial...
  94. pmc Measures of obesity and cardiovascular risk among men and women
    Rebecca P Gelber
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    J Am Coll Cardiol 52:605-15. 2008
    ....
  95. ncbi request reprint Dietary calcium, vitamin D, and the prevalence of metabolic syndrome in middle-aged and older U.S. women
    Simin Liu
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Diabetes Care 28:2926-32. 2005
    ..To examine whether and to what extent intakes of calcium and vitamin D are related to the metabolic syndrome in middle-aged or older women...
  96. ncbi request reprint Postmenopausal hormone therapy: new questions and the case for new clinical trials
    JoAnn E Manson
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Menopause 13:139-47. 2006
    ....
  97. ncbi request reprint A prospective study of dairy intake and the risk of type 2 diabetes in women
    Simin Liu
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Diabetes Care 29:1579-84. 2006
    ..Although studies have indicated that increased dairy intake may reduce risk of overweight and insulin resistance syndrome, data directly relating dairy intake to type 2 diabetes remain sparse...
  98. ncbi request reprint A prospective study of serum lipids and risk of diabetic macular edema in type 1 diabetes
    Biljana Miljanovic
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215, USA
    Diabetes 53:2883-92. 2004
    ..Lipid-lowering treatment among type 1 diabetic subjects, recommended to prevent cardiovascular disease, may also decrease risk of CSME, an important cause of vision loss...
  99. doi request reprint Sexual satisfaction and cardiovascular disease: the Women's Health Initiative
    Jennifer S McCall-Hosenfeld
    VA Boston Healthcare System, Boston, MA, USA
    Am J Med 121:295-301. 2008
    ..We investigated whether dissatisfaction with sexual activity, a domain of female sexual dysfunction, is associated with prevalent and incident cardiovascular disease in postmenopausal women...
  100. ncbi request reprint Alcohol consumption and type 2 diabetes: influence of genetic variation in alcohol dehydrogenase
    Joline W J Beulens
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes 56:2388-94. 2007
    ..We sought to investigate whether a polymorphism in the alcohol dehydrogenase 1c (ADH1C) gene modifies the association between alcohol consumption and type 2 diabetes...
  101. pmc Insulin sensitivity and insulin secretion determined by homeostasis model assessment and risk of diabetes in a multiethnic cohort of women: the Women's Health Initiative Observational Study
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Diabetes Care 30:1747-52. 2007
    ..However, prospective data regarding its relation to diabetes risk in ethnically diverse populations are limited...