JOSEPH MANDEVILLE

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc A receptor-based model for dopamine-induced fMRI signal
    Joseph B Mandeville
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA
    Neuroimage 75:46-57. 2013
  2. doi request reprint IRON fMRI measurements of CBV and implications for BOLD signal
    Joseph B Mandeville
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Neuroimage 62:1000-8. 2012
  3. pmc fMRI of cocaine self-administration in macaques reveals functional inhibition of basal ganglia
    Joseph B Mandeville
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging Massachusetts General Hospital, Boston, MA, USA
    Neuropsychopharmacology 36:1187-98. 2011
  4. ncbi request reprint Spin-echo MRI underestimates functional changes in microvascular cerebral blood plasma volume using exogenous contrast agent
    Joseph B Mandeville
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital MGH, Massachusetts Institute of Technology MIT, Harvard Medical School HMS, Boston, Massachusetts, USA
    Magn Reson Med 58:769-76. 2007
  5. ncbi request reprint Vascular filters of functional MRI: spatial localization using BOLD and CBV contrast
    J B Mandeville
    NMR Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Magn Reson Med 42:591-8. 1999
  6. ncbi request reprint Exogenous contrast agent improves sensitivity of gradient-echo functional magnetic resonance imaging at 9.4 T
    Joseph B Mandeville
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston 02129, USA
    Magn Reson Med 52:1272-81. 2004
  7. ncbi request reprint MRI measurement of the temporal evolution of relative CMRO(2) during rat forepaw stimulation
    J B Mandeville
    MGH NMR Center, Massachusetts General Hospital, Boston, Massachusetts, USA
    Magn Reson Med 42:944-51. 1999
  8. ncbi request reprint Regional sensitivity and coupling of BOLD and CBV changes during stimulation of rat brain
    J B Mandeville
    MGH NMR Center, Massachusetts General Hospital, Boston, Massachusetts, USA
    Magn Reson Med 45:443-7. 2001
  9. pmc Visual field map clusters in macaque extrastriate visual cortex
    Hauke Kolster
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Neurosci 29:7031-9. 2009
  10. ncbi request reprint Stereopsis activates V3A and caudal intraparietal areas in macaques and humans
    Doris Y Tsao
    Massachusetts General Hospital, NMR Center, Athinoula A Martinos Center, Charlestown, Massachusetts 02129, USA
    Neuron 39:555-68. 2003

Research Grants

  1. Iron fMRI: Improving Sensitivty and localization
    JOSEPH MANDEVILLE; Fiscal Year: 2006
  2. fMRI and neuronal activity in awake behavior
    JOSEPH MANDEVILLE; Fiscal Year: 2006
  3. MRI MEASUREMENT OF RELATIVE CMR02-- VALIDATION USING PET
    JOSEPH MANDEVILLE; Fiscal Year: 2002
  4. FMRI STUDY OF CNS PHYSIOLOGY DURING COCAINE RESPONSE
    JOSEPH MANDEVILLE; Fiscal Year: 2002

Collaborators

Detail Information

Publications28

  1. pmc A receptor-based model for dopamine-induced fMRI signal
    Joseph B Mandeville
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA
    Neuroimage 75:46-57. 2013
    ....
  2. doi request reprint IRON fMRI measurements of CBV and implications for BOLD signal
    Joseph B Mandeville
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Neuroimage 62:1000-8. 2012
    ..This article reviews the methodological advantages of the IRON method and how CBV measurements have informed our understanding of the BOLD response...
  3. pmc fMRI of cocaine self-administration in macaques reveals functional inhibition of basal ganglia
    Joseph B Mandeville
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging Massachusetts General Hospital, Boston, MA, USA
    Neuropsychopharmacology 36:1187-98. 2011
    ....
  4. ncbi request reprint Spin-echo MRI underestimates functional changes in microvascular cerebral blood plasma volume using exogenous contrast agent
    Joseph B Mandeville
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital MGH, Massachusetts Institute of Technology MIT, Harvard Medical School HMS, Boston, Massachusetts, USA
    Magn Reson Med 58:769-76. 2007
    ....
  5. ncbi request reprint Vascular filters of functional MRI: spatial localization using BOLD and CBV contrast
    J B Mandeville
    NMR Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Magn Reson Med 42:591-8. 1999
    ..Magn Reson Med 42:591-598, 1999...
  6. ncbi request reprint Exogenous contrast agent improves sensitivity of gradient-echo functional magnetic resonance imaging at 9.4 T
    Joseph B Mandeville
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston 02129, USA
    Magn Reson Med 52:1272-81. 2004
    ..The derived field dependencies for relative sensitivity and MRI estimates of the percentage change in CBV suggest that the benefits provided by exogenous agents will persist even at much higher magnetic fields than 9.4 T...
  7. ncbi request reprint MRI measurement of the temporal evolution of relative CMRO(2) during rat forepaw stimulation
    J B Mandeville
    MGH NMR Center, Massachusetts General Hospital, Boston, Massachusetts, USA
    Magn Reson Med 42:944-51. 1999
    ..A poststimulus undershoot in BOLD signal was quantitatively attributed to the temporal mismatch between changes in blood flow and volume, and not to the role of oxygen metabolism. Magn Reson Med 42:944-951, 1999...
  8. ncbi request reprint Regional sensitivity and coupling of BOLD and CBV changes during stimulation of rat brain
    J B Mandeville
    MGH NMR Center, Massachusetts General Hospital, Boston, Massachusetts, USA
    Magn Reson Med 45:443-7. 2001
    ..The use of contrast agent increased functional sensitivity in all parenchymal brain structures, with a strong but predictable dependence on the resting-state blood volume fraction. Magn Reson Med 45:443-447, 2001...
  9. pmc Visual field map clusters in macaque extrastriate visual cortex
    Hauke Kolster
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Neurosci 29:7031-9. 2009
    ..This novel view on the functional topography of area MT/V5 and satellites indicates that field map clusters are evolutionarily preserved and may be a fundamental organizational principle of the Old World primate visual cortex...
  10. ncbi request reprint Stereopsis activates V3A and caudal intraparietal areas in macaques and humans
    Doris Y Tsao
    Massachusetts General Hospital, NMR Center, Athinoula A Martinos Center, Charlestown, Massachusetts 02129, USA
    Neuron 39:555-68. 2003
    ..Thus, in both primate species a small cluster of areas at the parieto-occipital junction appears to be specialized for stereopsis...
  11. pmc Early time points perfusion imaging
    Kenneth K Kwong
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 54:1070-82. 2011
    ..A recipe to run ET was presented, with attention paid to the noise problem around the time of arrival (TOA) of the contrast agent...
  12. pmc Event-related single-shot volumetric functional magnetic resonance inverse imaging of visual processing
    Fa Hsuan Lin
    MGH HST Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Neuroimage 42:230-47. 2008
    ..Robust results from both single subject and group analyses demonstrate the sensitivity and feasibility of using volumetric InI in high temporal resolution investigations of human brain function...
  13. pmc Functional MRI of delayed chronic lithium treatment in rat focal cerebral ischemia
    Young R Kim
    Athinoula Martinos Center for Biomedical Imaging Massachusetts General Hospital, 149 13th Street, Room 2301, Charlestown, MA 02129, USA
    Stroke 39:439-47. 2008
    ..We further investigated neurohemodynamic aspects of the treatment-associated recovery by assessing the therapeutic efficacy of delayed chronic lithium treatment using functional MRI...
  14. pmc Inhibition of stimulated dopamine release and hemodynamic response in the brain through electrical stimulation of rat forepaw
    Y Iris Chen
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Room 2301, Charlestown, MA 02129, USA
    Neurosci Lett 431:231-5. 2008
    ..These data provide evidence for physiologic modulation caused by electroacupuncture at points near the median nerve...
  15. ncbi request reprint Transcription MRI: a new view of the living brain
    Philip K Liu
    Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Neuroscientist 14:503-20. 2008
    ..Transcription MRI will lend itself to myriad applications in living organs...
  16. ncbi request reprint fMRI of delayed albumin treatment during stroke recovery in rats: implication for fast neuronal habituation in recovering brains
    Young R Kim
    Athinoula Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Cereb Blood Flow Metab 27:142-53. 2007
    ..Taken together, these data suggest that restoration of fMRI response magnitudes, temporal profiles, and correlations with structure may reveal the extent and specific traits of albumin treatment associated stroke recovery...
  17. ncbi request reprint Faces and objects in macaque cerebral cortex
    Doris Y Tsao
    Athinoula A Martinos Center, Charlestown, Massachusetts 02129, USA
    Nat Neurosci 6:989-95. 2003
    ..Overall, our results suggest that humans and macaques share a similar brain architecture for visual object processing...
  18. ncbi request reprint Measurements of BOLD/CBV ratio show altered fMRI hemodynamics during stroke recovery in rats
    Young R Kim
    NMR Center MGH, Charlestown, Massachusetts 02129, USA
    J Cereb Blood Flow Metab 25:820-9. 2005
    ..These results suggest that stroke affects not only local hemodynamics and coupling but also other factors including neural connectivity...
  19. pmc Functional response of tumor vasculature to PaCO2: determination of total and microvascular blood volume by MRI
    Scott D Packard
    MGH NMR Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Neoplasia 5:330-8. 2003
    ..Furthermore, reduced reactivity of tumor vessels to a single physiological perturbation, such as hypercarbia, should not be construed as a generalized reduction of functional activity of the tumor vascular bed...
  20. pmc DNA-based MRI probes for specific detection of chronic exposure to amphetamine in living brains
    Christina H Liu
    Laboratory for Gene Transcript Targeting, Imaging and Repair, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Neurosci 29:10663-70. 2009
    ..The in vivo target specificity of these probes permits reliable MRI visualization of AMPH-induced differential elevations of fosB and Delta fosB mRNA in living brains...
  21. ncbi request reprint High resolution spatial mapping of nicotine action using pharmacologic magnetic resonance imaging
    Ji Kyung Choi
    Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Synapse 60:152-7. 2006
    ..The high spatial and temporal resolution of the phMRI technique lends itself well to further, more detailed, studies of nicotine dynamics...
  22. ncbi request reprint Correlation between brain reorganization, ischemic damage, and neurologic status after transient focal cerebral ischemia in rats: a functional magnetic resonance imaging study
    Rick M Dijkhuizen
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Neurosci 23:510-7. 2003
    ....
  23. doi request reprint Imaging brain regional and cortical laminar effects of selective D3 agonists and antagonists
    Ji Kyung Choi
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, 02129, USA
    Psychopharmacology (Berl) 212:59-72. 2010
    ..Dopamine D3 receptors (D3R) may be important therapeutic targets for both drug abuse and dyskinesias in Parkinson's disease; however, little is known about their functional circuitry...
  24. pmc Remifentanil administration reveals biphasic phMRI temporal responses in rat consistent with dynamic receptor regulation
    Christina H Liu
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA 02129, USA
    Neuroimage 34:1042-53. 2007
    ....
  25. ncbi request reprint Evidence that cerebral blood volume can provide brain activation maps with better spatial resolution than deoxygenated hemoglobin
    Joseph P Culver
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4525 Scott Avenue, St Louis, MO 63110, USA
    Neuroimage 27:947-59. 2005
    ..These results indicate that total hemoglobin and cerebral blood volume may have advantages as hemodynamic mapping contrasts, particularly for large amplitude, longer duration stimulus paradigms...
  26. ncbi request reprint Temporal comparison of functional brain imaging with diffuse optical tomography and fMRI during rat forepaw stimulation
    Andrew M Siegel
    Tufts University Bioengineering Center, Medford, MA 02155, USA
    Phys Med Biol 48:1391-403. 2003
    ....
  27. ncbi request reprint Characterization of event-related designs using BOLD and IRON fMRI
    Francisca P Leite
    Harvard MIT Division of Health Sciences and Technology, Cambridge, MA 02138, USA
    Neuroimage 29:901-9. 2006
    ..Small amounts of entropy can be traded for large gains in efficiency, particularly for the IRON method...
  28. ncbi request reprint Repeated fMRI using iron oxide contrast agent in awake, behaving macaques at 3 Tesla
    Francisca P Leite
    Massachusetts Institute of Technology, Department of Nuclear Engineering, Cambridge, Massachusetts 02139, USA
    Neuroimage 16:283-94. 2002
    ..Overall, the contrast agent produced a dramatic improvement in functional brain imaging results in the awake, behaving primate at this field strength. (c) 2002 Elsevier Science (USA)...

Research Grants10

  1. Iron fMRI: Improving Sensitivty and localization
    JOSEPH MANDEVILLE; Fiscal Year: 2006
    ..abstract_text> ..
  2. fMRI and neuronal activity in awake behavior
    JOSEPH MANDEVILLE; Fiscal Year: 2006
    ..Finally, we will test the neural-fMRI relationship in a higher-order region of visual cortex which appears to be specialized for processing faces and other visual objects. ..
  3. MRI MEASUREMENT OF RELATIVE CMR02-- VALIDATION USING PET
    JOSEPH MANDEVILLE; Fiscal Year: 2002
    ..Successful completion of the proposed studies will establish, a new tool for assessment of cerebral functional physiology and preface the application of these techniques to cerebral pathology. ..
  4. FMRI STUDY OF CNS PHYSIOLOGY DURING COCAINE RESPONSE
    JOSEPH MANDEVILLE; Fiscal Year: 2002
    ..These studies seek to validate the physiological basis of a promising new technology for study of psychoactive drug action in brain and to increase our understanding of the neurobiology of cocaine. ..