Research Topics
Species | Nikos MakrisSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Working memory network alterations and associated symptoms in adults with ADHD and Bipolar DisorderAriel Brown
Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Psychiatr Res 46:476-83. 2012..We conclude that comorbid ADHD + BPD is associated with alterations across anterior and posterior nodes of the working memory network, and symptoms of each disorder are related to anatomically and functionally distinct brain regions...
Effect of dopamine transporter gene (SLC6A3) variation on dorsal anterior cingulate function in attention-deficit/hyperactivity disorderAriel B Brown
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
Am J Med Genet B Neuropsychiatr Genet 153:365-75. 2010..Alterations in activation of attention and EF networks found previously to be involved in ADHD are likely influenced by SLC6A3 genotype. This genotype may contribute to heterogeneity of brain alterations found within ADHD samples...- Relationship of DAT1 and adult ADHD to task-positive and task-negative working memory networksAriel Beth Brown
Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States
Psychiatry Res 193:7-16. 2011..Further, we show that DMN suppression is likely linked to DAT1 and to severity of inattention in ADHD. DMN may therefore be a target of DAT1 effects, and lie on the path between the gene and inattention in ADHD... - Sex differences in the functional neuroanatomy of working memory in adults with ADHDEve M Valera
Department of Psychiatry, Massachusetts General Hospital, 149 13th St, Charlestown, MA 02129, USA
Am J Psychiatry 167:86-94. 2010..The authors examined sex differences in the neural functioning of adults with ADHD during performance of a verbal working memory task... 
A review and new report of medial temporal lobe dysfunction as a vulnerability indicator for schizophrenia: a magnetic resonance imaging morphometric family study of the parahippocampal gyrusLarry J Seidman
Commonwealth Research Center, Harvard Medical School, Department of Psychiatry, Massachusetts Mental Health Center, Boston, MA, USA
Schizophr Bull 29:803-30. 2003..Implications of genetic risk studies for prodromal research are discussed...- Anterior cingulate volumetric alterations in treatment-naïve adults with ADHD: a pilot studyNikos Makris
Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
J Atten Disord 13:407-13. 2010..Thus its anatomical alteration may give rise to impulsivity, hyperactivity and inattention, which are cardinal behavioral manifestations of ADHD... - A preliminary study of dopamine D4 receptor genotype and structural brain alterations in adults with ADHDMichael C Monuteaux
Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Am J Med Genet B Neuropsychiatr Genet 147:1436-41. 2008..These result support the heterogeneity of ADHD and provides insights as to its underlying pathophysiology... - Frontal white matter and cingulum diffusion tensor imaging deficits in alcoholismGordon J Harris
Department of Neurology, Athinoula A Martinos Center, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Alcohol Clin Exp Res 32:1001-13. 2008..In the present study, we examined the integrity of white matter tracts that are critical to frontal and limbic connectivity... - Cerebellum, language, and cognition in autism and specific language impairmentSteven M Hodge
Center for Morphometric Analysis, Massachusetts General Hospital, Boston, MA 02114, USA
J Autism Dev Disord 40:300-16. 2010..These findings suggest ALI and SLI subjects show abnormalities in neurodevelopment of fronto-corticocerebellar circuits that manage motor control and the processing of language, cognition, working memory, and attention... - Regional prefrontal cortex gray matter volumes in youth at familial risk for schizophrenia from the Harvard Adolescent High Risk StudyIsabelle M Rosso
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Schizophr Res 123:15-21. 2010..We conducted a region-of-interest morphometric study of prefrontal subregions in adolescent and young adult relatives of schizophrenia patients... - Cortical thinning of the attention and executive function networks in adults with attention-deficit/hyperactivity disorderNikos Makris
Departments of Neurology and Radiology Services, Center for Morphometric Analysis, Health Sciences and Technology Athinoula A Martinos Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
Cereb Cortex 17:1364-75. 2007..This is the first documentation that ADHD in adults is associated with thinner cortex in the cortical networks that modulate attention and EF... - Attention and executive systems abnormalities in adults with childhood ADHD: A DT-MRI study of connectionsNikos Makris
Harvard Medical School Departments of Neurology and Radiology Services, Center for Morphometric Analysis, Massachusetts General Hospital, Boston, MA 02129, USA
Cereb Cortex 18:1210-20. 2008..The demonstration of FA abnormalities in the CB and SLF II in adults with childhood ADHD provides further support for persistent structural abnormalities into adulthood... - Hypothalamic abnormalities in schizophrenia: sex effects and genetic vulnerabilityJill M Goldstein
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Biol Psychiatry 61:935-45. 2007..We tested the hypothesis that normal hypothalamic sexual dimorphism is disrupted in schizophrenia... - Decreased volume of left and total anterior insular lobule in schizophreniaNikos Makris
Athinoula A Martinos Center, Harvard Medical School Department of Neurology, Massachusetts General Hospital, Boston, MA 02129, United States
Schizophr Res 83:155-71. 2006.... - Neural substrates of impaired sensorimotor timing in adult attention-deficit/hyperactivity disorderEve M Valera
Clinical and Research Programs in Pediatric Psychopharmacology and Adult Attention Deficit Hyperactivity Disorder, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Biol Psychiatry 68:359-67. 2010..Also, the neural substrates of these deficits are largely unknown for both youth and adults with ADHD. The present study examined subsecond sensorimotor timing and its neural substrates in ADHD adults... - A functional MRI study of working memory in adolescents and young adults at genetic risk for bipolar disorder: preliminary findingsHeidi W Thermenos
Division of Public Psychiatry, Department of Psychiatry, Massachusetts Mental Health Center, Beth Israel Deaconess Medical Center, Boston, USA
Bipolar Disord 13:272-86. 2011.... - Frontal connections and cognitive changes in normal aging rhesus monkeys: a DTI studyNikos Makris
Harvard Medical School Department of Neurology, Center for Morphometric Analysis, Massachusetts General Hospital, Boston, MA 02129, United States
Neurobiol Aging 28:1556-67. 2007..To our knowledge this is the first investigation reporting such alterations in the aging monkey... - Neuroanatomic substrates of sex differences in language dysfunction in schizophrenia: a pilot studyDeborah J Walder
Psychiatric Neuroscience Division, Harvard Medical School Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02120, USA
Schizophr Res 90:295-301. 2007.... - Sex differences in stress response circuitry activation dependent on female hormonal cycleJill M Goldstein
Department of Psychiatry, and Connors Center for Women s Health and Gender Biology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
J Neurosci 30:431-8. 2010.... - Evidence for reduced cerebellar volumes in trichotillomaniaNancy J Keuthen
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
Biol Psychiatry 61:374-81. 2007..Limited knowledge exists regarding the neurobiology of trichotillomania (TTM). Cerebellum (CBM) volumes were explored, given its role in complex, coordinated motor sequences... - Dorsolateral prefrontal and anterior cingulate cortex volumetric abnormalities in adults with attention-deficit/hyperactivity disorder identified by magnetic resonance imagingLarry J Seidman
Harvard Medical School, Department of Psychiatry, Center for Morphometric Analysis, Massachusetts General Hospital, Fruit Street, Boston, MA 02114, USA
Biol Psychiatry 60:1071-80. 2006..This structural MRI study used an a priori region of interest approach... - Acupuncture mobilizes the brain's default mode and its anti-correlated network in healthy subjectsKathleen K S Hui
Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129, USA
Brain Res 1287:84-103. 2009..Our results suggest that acupuncture mobilizes the anti-correlated functional networks of the brain to mediate its actions, and that the effect is dependent on the psychophysical response... - Cortical thickness abnormalities in cocaine addiction--a reflection of both drug use and a pre-existing disposition to drug abuse?Nikos Makris
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Neuron 60:174-88. 2008..These observations suggest that brain structure abnormalities in addicts are related in part to drug use and in part to predisposition toward addiction... - Microstructural abnormalities in subcortical reward circuitry of subjects with major depressive disorderAnne J Blood
Depression Clinic and Research Program, Mood and Motor Control Laboratory, Addiction Research Program, Laboratory of Neuroimaging and Genetics, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
PLoS ONE 5:e13945. 2010..There has been little investigation in MDD of midbrain and subcortical regions central to reward/aversion function, such as the ventral tegmental area/substantia nigra (VTA/SN), and medial forebrain bundle (MFB)... - Gray matter alterations in adults with attention-deficit/hyperactivity disorder identified by voxel based morphometryLarry J Seidman
Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Biol Psychiatry 69:857-66. 2011..This study used voxel based morphometry and applied an a priori region of interest approach based on our previous work, as well as from well-developed neuroanatomical theories of ADHD... - Further understanding of the comorbidity between Attention-Deficit/Hyperactivity Disorder and bipolar disorder in adults: an MRI study of cortical thicknessNikos Makris
Department of Psychiatry and Neurology, Harvard Medical School, Boston, MA, USA
Psychiatry Res 202:1-11. 2012..Attention to comorbidity is necessary to help clarify the heterogeneous neuroanatomy of both BPD and ADHD... - Diagnostic and sex effects on limbic volumes in early-onset bipolar disorder and schizophreniaJean A Frazier
Department of Psychiatry, Harvard Medical School, Massachusetts, USA
Schizophr Bull 34:37-46. 2008..The limbic structures in early-onset schizophrenia-spectrum illness (SZ) and bipolar disorder (BPD) were studied to discern patterns associated with diagnosis and sex... - MRI-based surface-assisted parcellation of human cerebellar cortex: an anatomically specified method with estimate of reliabilityNikos Makris
Center for Morphometric Analysis, MGH East, 149 13th Street, Charlestown, MA 02129, USA
Neuroimage 25:1146-60. 2005..933. Whereas the individual units provide a high level of detail and anatomical specificity, the clusters add flexibility to the analysis by providing higher reliability... - Functional magnetic resonance imaging of methylphenidate and placebo in attention-deficit/hyperactivity disorder during the multi-source interference taskGeorge Bush
Departments of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Arch Gen Psychiatry 65:102-14. 2008..Stimulant medications are effective treatments for ADHD, but their neural effects have not been fully characterized... - Left hippocampal volume as a vulnerability indicator for schizophrenia: a magnetic resonance imaging morphometric study of nonpsychotic first-degree relativesLarry J Seidman
Neuropsychology Laboratory, Massachusetts Mental Health Center, 74 Fenwood Rd, Boston, MA 02115, USA
Arch Gen Psychiatry 59:839-49. 2002.... - Hormonal cycle modulates arousal circuitry in women using functional magnetic resonance imagingJill M Goldstein
Department of Psychiatry, Harvard Medical School, Brigham and Women s Hospital, Connors Center for Women s Health and Gender Biology, Boston, Massachusetts 02115, USA
J Neurosci 25:9309-16. 2005..Findings have important implications for normal sex-specific physiological functioning and may contribute to understanding higher rates of mood and anxiety disorders in women and differential sensitivity to trauma than men... - Automatically parcellating the human cerebral cortexBruce Fischl
Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, MGH MIT Harvard Medical School, Massachusetts General Hospital, 13th Street, Charlestown, MA 02129, USA
Cereb Cortex 14:11-22. 2004..Examples are given from two different training sets generated using different neuroanatomical conventions, illustrating the flexibility of the algorithm. The technique is shown to be comparable in accuracy to manual labeling... - White matter abnormalities in children with and at risk for bipolar disorderJean A Frazier
Department of Psychiatry, Harvard Medical School, Boston, USA
Bipolar Disord 9:799-809. 2007..To more fully examine this possibility, we scanned children with DSM-IV BPD and compared them to healthy peers and children at risk for BPD (AR-BPD), defined as having a first-degree relative with the disorder... - Association of a polymorphism near CREB1 with differential aversion processing in the insula of healthy participantsRoy H Perlis
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Arch Gen Psychiatry 65:882-92. 2008.... - Structural brain abnormalities among relatives of patients with schizophrenia: implications for linkage studiesStephen V Faraone
Harvard Medical School Department of Psychiatry at the Massachusetts Mental Health Center, Boston, MA, USA
Schizophr Res 60:125-40. 2003.... - Human cerebral cortex: a system for the integration of volume- and surface-based representationsNikos Makris
Center for Morphometric Analysis, MGH East, 149 13th Street, Charlestown, MA 02129, USA
Neuroimage 33:139-53. 2006..This system of topographical analysis of the cerebral cortex is consistent with current views of cortical development and neural systems organization of the human and non-human primate brain... - Cortical gray matter differences identified by structural magnetic resonance imaging in pediatric bipolar disorderJean A Frazier
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Bipolar Disord 7:555-69. 2005..Cortical gray matter (GM) volume deficits have been reported in some studies of adults with BPD; this study assessed the presence of such deficits in children with BPD... - Sex differences in prefrontal cortical brain activity during fMRI of auditory verbal working memoryJill M Goldstein
Department of Psychiatry, Harvard Medical School, Boston, MA 02120, USA
Neuropsychology 19:509-19. 2005..The findings suggest that combining men and women in fMRI studies of cognition may obscure or bias results... - The integrated response of the human cerebro-cerebellar and limbic systems to acupuncture stimulation at ST 36 as evidenced by fMRIKathleen K S Hui
Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Room 2301, Charlestown, MA 02129, USA
Neuroimage 27:479-96. 2005..The study provides preliminary evidence for an integrated response of the human cerebro-cerebellar and limbic systems to acupuncture stimulation at ST 36 that correlates with the psychophysical response... - An fMRI study of working memory in persons with bipolar disorder or at genetic risk for bipolar disorderHeidi W Thermenos
Department of Psychiatry, Harvard Medical School, Massachusetts Mental Health Center Division of Public Psychiatry, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Am J Med Genet B Neuropsychiatr Genet 153:120-31. 2010..Persons with BD and RELs exhibit altered activity in the frontopolar cortex and insula, which may represent biomarkers of genetic risk for BD... - The extreme capsule in humans and rethinking of the language circuitryNikos Makris
Departments of Psychiatry and Neurology, Harvard Medical School, Boston, MA 02129, USA
Brain Struct Funct 213:343-58. 2009.... - Characterization of the "deqi" response in acupunctureKathleen K S Hui
Athinoula A, Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
BMC Complement Altern Med 7:33. 2007.... - Delineation of the middle longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI studyNikos Makris
Harvard Medical School Department of Psychiatry, Center for Morphometric Analysis, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, 02129, USA
Cereb Cortex 19:777-85. 2009..Given the location of MdLF between the IPL (angular gyrus) and the STG, it is suggested that MdLF could have a role in language and attention functions... - Time-variant fMRI activity in the brainstem and higher structures in response to acupunctureVitaly Napadow
Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
Neuroimage 47:289-301. 2009..Our protocol also demonstrates a fMRI approach to study habituation and other time-variant phenomena over longer time durations... - Sequence-independent segmentation of magnetic resonance imagesBruce Fischl
Department of Radiology, MGH, Athinoula A Martinos Center, Harvard Medical School, Charlestown, MA 02129, USA
Neuroimage 23:S69-84. 2004..This sequence has the added benefit of allowing the explicit estimation of T2* and of reducing test-retest intensity variability... - Decreased volume of the brain reward system in alcoholismNikos Makris
Athinoula A Martinos Center, Harvard Medical School Department of Neurology, Boston, Massachusetts, USA
Biol Psychiatry 64:192-202. 2008..We examined whether reward-network brain volumes are reduced in alcoholics and how volumes of subcomponents within this system are correlated with memory and drinking history... - Covariance modeling of MRI brain volumes in memory circuitry in schizophrenia: Sex differences are criticalBrandon Abbs
Brigham and Women s Hospital, Connors Center for Women s Health and Gender Biology, 1620 Tremont St BC 3 34, Boston, MA 02120, USA
Neuroimage 56:1865-74. 2011..These results illustrate the utility of a unique covariance structure modeling approach that yields important new knowledge for understanding the nature of schizophrenia... - Atomoxetine increases fronto-parietal functional MRI activation in attention-deficit/hyperactivity disorder: a pilot studyGeorge Bush
Harvard Medical School, Department of Psychiatry, Boston, MA 02114, USA
Psychiatry Res 211:88-91. 2013..These results suggest that ATMX and MPH have similar but not identical brain effects... - Food motivation circuitry hypoactivation related to hedonic and nonhedonic aspects of hunger and satiety in women with active anorexia nervosa and weight-restored women with anorexia nervosaLaura M Holsen
Division of Women s Health, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
J Psychiatry Neurosci 37:322-32. 2012.... - Reliability of MRI-derived measurements of human cerebral cortical thickness: the effects of field strength, scanner upgrade and manufacturerXiao Han
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
Neuroimage 32:180-94. 2006.... - The occipitofrontal fascicle in humans: a quantitative, in vivo, DT-MRI studyNikos Makris
Harvard Medical School, Department of Neurology, Center for Morphometric Analysis, Massachusetts General Hospital, Boston, MA 02129, USA
Neuroimage 37:1100-11. 2007..The OFF may have a role in visual spatial processing along with SLF II... - Segmentation of subcomponents within the superior longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI studyNikos Makris
Harvard Medical School Department of Neurology, Center for Morphometric Analysis, Massachusetts General Hospital, Boston, MA 02129, USA
Cereb Cortex 15:854-69. 2005..Since DT-MRI allows the precise definition of only the stem portion of each fiber pathway, the origin and termination of the subdivisions of SLF are extrapolated from the available data in experimental material from non-human primates... - WebParc: a tool for analysis of the topography and volume of stroke from MRIDavid N Kennedy
Center for Morphometric Analysis, Massachusetts General Hospital, 149 13th Street, Charlestown, Boston, MA, USA
Med Biol Eng Comput 48:215-28. 2010..This article is an overview of its base-line operation with quantitative anatomic characterization of lesion size and location in terms of stroke distribution within the separate gray and white matter compartments of the brain... - Metabolic activity in the insular cortex and hypothalamus predicts hot flashes: an FDG-PET studyHadine Joffe
Center for Women s Mental Health, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston Massachusetts 02114, USA
J Clin Endocrinol Metab 97:3207-15. 2012..Previous studies have implicated the insula during the perception of hot flashes and the hypothalamus in thermoregulatory dysfunction... - Decreased absolute amygdala volume in cocaine addictsNikos Makris
Motivation and Emotion Neuroscience Collaboration, Department of Radiology, Harvard Medical School, Boston, MA 02129, USA
Neuron 44:729-40. 2004..These findings argue for a condition that predisposes the individual to cocaine dependence by affecting the amygdala, or a primary event early in the course of cocaine use... - Role of the medial temporal lobes in relational memory: neuropsychological evidence from a cued recognition paradigmIrene P Kan
Memory Disorders Research Center, Boston University School of Medicine, Boston VA Healthcare System, Boston, MA 02130, USA
Neuropsychologia 45:2589-97. 2007..These data provide further support for the idea that the hippocampus plays a critical role in relational memory, even when associative information need not be retrieved intentionally... - Structural brain imaging of attention-deficit/hyperactivity disorderLarry J Seidman
Pediatric Psychopharmacology Unit and Psychiatric Neuroscience Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
Biol Psychiatry 57:1263-72. 2005..These results suggest that the brain is altered in a more widespread manner than has been previously hypothesized. Developmental studies are needed to address the evolution of this brain disorder into adulthood... - Selectively reduced regional cortical volumes in post-traumatic stress disorderScott L Rauch
Psychiatric Neuroimaging Research Group, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, 13th St, Bldg 149, CNY 9, Charlestown, MA 02129, USA
Neuroreport 14:913-6. 2003..These results are consistent with contemporary schemes regarding functional and structural dissection of frontal cortex, and suggest specific regional cortical pathology in PTSD... - MRI-based anatomical model of the human head for specific absorption rate mappingNikos Makris
Department of Psychiatry, Neurology and Radiology Services, Center for Morphometric Analysis, HST Athinoula A Martinos Center, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02129, USA
Med Biol Eng Comput 46:1239-51. 2008.... - Towards conceptualizing a neural systems-based anatomy of attention-deficit/hyperactivity disorderNikos Makris
Harvard Medical School Department of Psychiatry, Boston University School of Medicine, Boston, MA 02129, USA
Dev Neurosci 31:36-49. 2009..Characterizing these neural systems using neuroimaging could be critical for the description of structural endophenotypes, and may provide the capability of in vivo categorization and correlation with behavior and genes... - Volumetric parcellation methodology of the human hypothalamus in neuroimaging: normative data and sex differencesNikos Makris
Department of Psychiatry, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA
Neuroimage 69:1-10. 2013.... - Brain correlates of autonomic modulation: combining heart rate variability with fMRIVitaly Napadow
MGH MIT HMS Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02119, USA
Neuroimage 42:169-77. 2008..Our approach should be optimized and applied to study the human brain correlates of autonomic modulation for various stimuli in both physiological and pathological states... - Microstructural status of ipsilesional and contralesional corticospinal tract correlates with motor skill in chronic stroke patientsJudith D Schaechter
MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA
Hum Brain Mapp 30:3461-74. 2009.... - A preliminary morphometric magnetic resonance imaging study of regional brain volumes in body dysmorphic disorderScott L Rauch
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Building 149, 139th Street, 9th Floor, Charlestown, MA 02129, USA
Psychiatry Res 122:13-9. 2003..the comparison group. Findings with respect to the caudate nucleus are consistent with both the conceptualization of BDD as an obsessive-compulsive spectrum disorder, and the 'striatal topography model' of obsessive-compulsive disorders... - Automated brainstem co-registration (ABC) for MRIVitaly Napadow
Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA
Neuroimage 32:1113-9. 2006..The use of easily available and validated tools (AFNI and FSL) for this method should ease adoption by other investigators interested in brainstem data group analysis... - An introduction to MR imaging-based stroke morphometryNikos Makris
Department of Neurology, Harvard Medical School, Charlestown, MA, USA
Neuroimaging Clin N Am 15:325-39, x. 2005..These samples highlight anatomic-based considerations regarding the nature of stroke and its repercussions within the brain parenchyma... - Human cerebellum: surface-assisted cortical parcellation and volumetry with magnetic resonance imagingNikos Makris
Massachusetts General Hospital, USA
J Cogn Neurosci 15:584-99. 2003..The SAP technique makes it possible to represent multimodal structural and functional imaging data on the flattened surface of the cerebellar cortex as illustrated in one functional MRI experiment... - Anxiety sensitivity correlates with two indices of right anterior insula structure in specific animal phobiaIsabelle M Rosso
Neuroimaging Center, McLean Hospital, Belmont, Massachusetts 02478, USA
Depress Anxiety 27:1104-10. 2010..We examined whether AS was significantly correlated with right anterior insula volume and thickness among adults with specific animal phobia (SAP) and healthy comparison (HC) subjects... - Abnormal asymmetry in language association cortex in autismMartha R Herbert
Center for Morphometric Analysis, Massachusetts General Hospital, CNY 149, Room 6012, Boston, MA 02114, USA
Ann Neurol 52:588-96. 2002..In boys with autism, language and social/face processing-related regions displayed abnormal asymmetry. These structural abnormalities may relate to language and social disturbances observed in autism... - Impact of normal sexual dimorphisms on sex differences in structural brain abnormalities in schizophrenia assessed by magnetic resonance imagingJill M Goldstein
Massachusetts Mental Health Center, Harvard Institute of Psychiatric Epidemiology and Genetics, 74 Fenwood Rd, Boston, MA 02115, USA
Arch Gen Psychiatry 59:154-64. 2002.... - Somatotopic activation in the human trigeminal pain pathwayAlex F M DaSilva
Center for Pain Functional Neuroimaging and Therapy Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02129, USA
J Neurosci 22:8183-92. 2002..This approach will be useful for exploring central correlates of plasticity in models of experimental and clinical pain... - Effects of electroacupuncture versus manual acupuncture on the human brain as measured by fMRIVitaly Napadow
Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
Hum Brain Mapp 24:193-205. 2005.... - Neurophysiology and neuroanatomy of pitch perception: auditory cortexMark Jude Tramo
Department of Neurology, Harvard Medical School, and Massachusetts General Hospital, The Institute for Music and Brain Science, Boston, 02114, USA
Ann N Y Acad Sci 1060:148-74. 2005..Advancing knowledge about the neural coding of pitch is of fundamental importance to the future design of neurobionic therapies for hearing loss... - White matter abnormalities in dystonia normalize after botulinum toxin treatmentAnne J Blood
Department of Neurology, Massachusetts General Hospital, Charlestown 02129, and Harvard Medical School, Boston, Massachusetts, USA
Neuroreport 17:1251-5. 2006..This raises the possibility that we have observed activity-dependent white matter plasticity in the adult human brain... - A study of syntactic processing in aphasia II: neurological aspectsDavid Caplan
Neuropsychology Laboratory, Massachusetts General Hospital, Boston, MA 02114, USA
Brain Lang 101:151-77. 2007..The data are consistent with a model in which the neural tissue that is responsible for the operations underlying sentence comprehension and syntactic processing is localized in different neural regions in different individuals... - Multimodal neuroimaging dissociates hemodynamic and electrophysiological correlates of error processingYigal Agam
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02215, USA
Proc Natl Acad Sci U S A 108:17556-61. 2011..These findings suggest that the PCC generates the ERN and communicates with the dACC to subserve error processing. They challenge current models that view fMRI activation of the dACC as the hemodynamic reflection of the ERN...