L Mahadevan

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Force of an actin spring
    Jennifer H Shin
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Biophys J 92:3729-33. 2007
  2. ncbi request reprint Self-organized origami
    L Mahadevan
    Division of Engineering and Applied Sciences and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Science 307:1740. 2005
  3. pmc Biomimetic ratcheting motion of a soft, slender, sessile gel
    L Mahadevan
    Department of Applied Mathematics and Theoretical Physics, Cambridge University, Cambridge CB3 0WA, United Kingdom
    Proc Natl Acad Sci U S A 101:23-6. 2004
  4. pmc Relating microstructure to rheology of a bundled and cross-linked F-actin network in vitro
    J H Shin
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Proc Natl Acad Sci U S A 101:9636-41. 2004
  5. ncbi request reprint Gravitational stability of suspensions of attractive colloidal particles
    Chanjoong Kim
    Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 99:028303. 2007
  6. ncbi request reprint Scaling of F-actin network rheology to probe single filament elasticity and dynamics
    M L Gardel
    Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 93:188102. 2004
  7. pmc Calcium regulation of an actin spring
    Barney K Tam
    Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Biophys J 97:1125-9. 2009
  8. doi request reprint Adaptive fluid-infused porous films with tunable transparency and wettability
    Xi Yao
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Nat Mater 12:529-34. 2013
  9. pmc A quantitative analysis of contractility in active cytoskeletal protein networks
    Poul M Bendix
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA
    Biophys J 94:3126-36. 2008
  10. pmc On the growth and form of the gut
    Thierry Savin
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 476:57-62. 2011

Collaborators

Detail Information

Publications70

  1. pmc Force of an actin spring
    Jennifer H Shin
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Biophys J 92:3729-33. 2007
    ..Thus, the elastic strain energy stored in the acrosome bundle is more than sufficient to power the acrosome reaction through the egg envelope...
  2. ncbi request reprint Self-organized origami
    L Mahadevan
    Division of Engineering and Applied Sciences and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Science 307:1740. 2005
    ....
  3. pmc Biomimetic ratcheting motion of a soft, slender, sessile gel
    L Mahadevan
    Department of Applied Mathematics and Theoretical Physics, Cambridge University, Cambridge CB3 0WA, United Kingdom
    Proc Natl Acad Sci U S A 101:23-6. 2004
    ..These ideas are therefore also applicable to technological situations that involve moving small, soft solids on substrates...
  4. pmc Relating microstructure to rheology of a bundled and cross-linked F-actin network in vitro
    J H Shin
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Proc Natl Acad Sci U S A 101:9636-41. 2004
    ..We show how the structure of the actin network is modified as the scruin concentration is varied, and we correlate these structural changes to variations in the resultant network elasticity...
  5. ncbi request reprint Gravitational stability of suspensions of attractive colloidal particles
    Chanjoong Kim
    Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 99:028303. 2007
    ..We also determine the relationship between the strength of the depletion attraction and the magnitude of the compressional modulus...
  6. ncbi request reprint Scaling of F-actin network rheology to probe single filament elasticity and dynamics
    M L Gardel
    Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 93:188102. 2004
    ..1-10 rad/sec. Moreover, the nonlinear strain stiffening of such networks exhibits a universal form as a function of prestress; this is quantitatively explained by the full force-extension relation of single semiflexible filaments...
  7. pmc Calcium regulation of an actin spring
    Barney K Tam
    Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Biophys J 97:1125-9. 2009
    ..Our experiments and theory suggest that calcium sequentially binds to calmodulin molecules decorating the actin filaments. This binding leads to a collective wave of untwisting of the actin filaments that drives bundle extension...
  8. doi request reprint Adaptive fluid-infused porous films with tunable transparency and wettability
    Xi Yao
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Nat Mater 12:529-34. 2013
    ..This strategy should make possible the rational design of tunable, multifunctional adaptive materials for a broad range of applications...
  9. pmc A quantitative analysis of contractility in active cytoskeletal protein networks
    Poul M Bendix
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA
    Biophys J 94:3126-36. 2008
    ..Our results suggest that cellular contractility can be sensitively regulated by tuning the (local) activity of molecular motors and the cross-linker density and binding affinity...
  10. pmc On the growth and form of the gut
    Thierry Savin
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 476:57-62. 2011
    ....
  11. ncbi request reprint How things get stuck: kinetics, elastohydrodynamics, and soft adhesion
    Madhav Mani
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 108:226104. 2012
    ..Our results also suggest that the bound particle is susceptible to fluctuation-driven instabilities parallel to the substrate...
  12. pmc Structural dynamics of an actin spring
    L Mahadevan
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA
    Biophys J 100:839-44. 2011
    ..It also illuminates the general mechanism by which energy may be stored in conformational changes and released cooperatively in ordered macromolecular assemblies...
  13. ncbi request reprint Gravitational collapse of colloidal gels
    S Manley
    Department of Physics and DEAS, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 94:218302. 2005
    ..In both cases, the rate of collapse is backflow limited, while its overall magnitude is determined by a balance between gravitational stress and network elastic stress...
  14. ncbi request reprint Elastic behavior of cross-linked and bundled actin networks
    M L Gardel
    Department of Physics, Harvard University, Cambridge, MA 02138, USA
    Science 304:1301-5. 2004
    ..We parameterize the full range of behavior in a state diagram and elucidate its origin with a robust model...
  15. ncbi request reprint Dynamics of surfactant-driven fracture of particle rafts
    Dominic Vella
    Division of Engineering and Applied Sciences, Harvard University, Pierce Hall, Cambridge Massachusetts 02138, USA
    Phys Rev Lett 96:178301. 2006
    ..Further, the velocity of propagation is not constant in time and the length of the crack scales as t(3/4). More broadly, this surfactant-induced rupture of interfacial rafts suggests ways to manipulate them for applications...
  16. pmc Collective thermoregulation in bee clusters
    Samuel A Ocko
    Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J R Soc Interface 11:20131033. 2014
    ..Our theory also makes testable hypotheses for the response of the cluster to external temperature inhomogeneities and suggests strategies for biomimetic thermoregulation. ..
  17. ncbi request reprint Strategies for cell shape control in tip-growing cells
    Otger Campàs
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Am J Bot 99:1577-82. 2012
    ..Here we study the shape of tip-growing, walled cells, which have evolved a polar mode of cell morphogenesis leading to characteristic filamentous cell morphologies that extend only apically...
  18. pmc Evolution of spur-length diversity in Aquilegia petals is achieved solely through cell-shape anisotropy
    Joshua R Puzey
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Proc Biol Sci 279:1640-5. 2012
    ....
  19. pmc Actin network growth under load
    Otger Campàs
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA
    Biophys J 102:1049-58. 2012
    ....
  20. pmc A biophysical indicator of vaso-occlusive risk in sickle cell disease
    David K Wood
    Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Sci Transl Med 4:123ra26. 2012
    ....
  21. pmc Limbless undulatory propulsion on land
    Z V Guo
    School of Engineering and Applied Sciences and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 105:3179-84. 2008
    ..Our model also allows us to pose and solve a variety of optimization problems such as those associated with maximum speed and mechanical efficiency, thus defining the performance envelope of this mode of locomotion...
  22. pmc Nonlinear mechanics of soft fibrous networks
    A Kabla
    Division of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA
    J R Soc Interface 4:99-106. 2007
    ..A simple microscopic model allows us to explain these features of our observations, and provides us with a baseline framework to understand active biomechanical networks...
  23. pmc Hygromorphs: from pine cones to biomimetic bilayers
    E Reyssat
    School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA
    J R Soc Interface 6:951-7. 2009
    ..Our work unifies varied observations of natural hygromorphs and suggests interesting biomimetic analogues, which we illustrate using an artificial flower with a controllable blooming and closing response...
  24. ncbi request reprint Physical limits and design principles for plant and fungal movements
    Jan M Skotheim
    Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge CB3 0WA, UK
    Science 308:1308-10. 2005
    ..Our study also suggests a design principle for nonmuscular hydraulically actuated structures: Rapid actuation requires either small size or the enhancement of motion on large scales via elastic instabilities...
  25. pmc Non-equilibration of hydrostatic pressure in blebbing cells
    Guillaume T Charras
    Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 435:365-9. 2005
    ..Motion of the fluid relative to the network generates spatially heterogeneous transients in the pressure field, and can be described in the framework of poroelasticity...
  26. pmc Physiological and pathological population dynamics of circulating human red blood cells
    John M Higgins
    Center for Systems Biology and Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 107:20587-92. 2010
    ..More generally we illustrate how clinical laboratory data can be used to develop and to test a dynamic model of human pathophysiology with potential clinical utility...
  27. pmc Implications of a poroelastic cytoplasm for the dynamics of animal cell shape
    T J Mitchison
    Department Systems Biology, Harvard Medical School, Boston, MA, USA
    Semin Cell Dev Biol 19:215-23. 2008
    ..Testing these hypotheses is not easy, as water is a difficult analyte to track, and will require a joint effort of the cytoskeleton and ion physiology communities...
  28. pmc Quantifying cell-generated mechanical forces within living embryonic tissues
    Otger Campàs
    1 School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA 2 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts, USA 3 Vascular Biology Program, Children s Hospital, Boston, Massachusetts, USA 4 Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA 5
    Nat Methods 11:183-9. 2014
    ..4 nN μm(-2)) are dependent on myosin II activity and are more than twofold larger than stresses generated by cells of embryonic tooth mesenchyme, either within cultured aggregates or in developing whole mouse mandibles. ..
  29. ncbi request reprint Elastic platonic shells
    Ee Hou Yong
    Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 111:177801. 2013
    ..We construct a minimal Landau theory for the transition using quadratic and cubic invariants of the spherical harmonic modes. Our approach suggests methods to engineer shape into soft spherical shells using a frozen defect topology. ..
  30. pmc Controlling the orientation and synaptic differentiation of myotubes with micropatterned substrates
    Jacinthe Gingras
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA
    Biophys J 97:2771-9. 2009
    ..Our results represent what we believe is a new approach for musculoskeletal tissue engineering, and our model sheds light on mechanisms of myotube alignment in vivo...
  31. ncbi request reprint Solenoids and plectonemes in stretched and twisted elastomeric filaments
    A Ghatak
    Division of Engineering and Applied Sciences, Harvard University, Cambridge, 02138 Massachusetts, USA
    Phys Rev Lett 95:057801. 2005
    ..Extension and relaxation experiments on these phases show the presence of large hysteresis loops and sawtooth-like force-displacement curves which are different for the plectoneme and the solenoid...
  32. pmc Power-limited contraction dynamics of Vorticella convallaria: an ultrafast biological spring
    A Upadhyaya
    Department of Physics and G R Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Biophys J 94:265-72. 2008
    ..We corroborate this by using beads as markers on the stalk and find that the contraction starts at the cell body and proceeds down the stalk at a speed that exceeds the velocity of the cell body...
  33. pmc Statistical dynamics of flowing red blood cells by morphological image processing
    John M Higgins
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, United States of America
    PLoS Comput Biol 5:e1000288. 2009
    ....
  34. ncbi request reprint Bending stiffness of a crystalline actin bundle
    Jennifer H Shin
    Department of Mechanical Engineering, M I T, Cambridge, MA 02139, USA
    J Mol Biol 337:255-61. 2004
    ....
  35. pmc Growth, geometry, and mechanics of a blooming lily
    Haiyi Liang
    Engineering and Applied Sciences, Organismic and Evolutionary Biology, Wyss Institute, Kavli Institute, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 108:5516-21. 2011
    ..This functional morphology suggests new biomimetic designs for deployable structures using boundary or edge actuation rather than the usual bulk or surface actuation...
  36. pmc Botanical ratchets
    I M Kulic
    Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA
    Proc Biol Sci 276:2243-7. 2009
    ....
  37. ncbi request reprint Lift-off instability during the impact of a drop on a solid surface
    John M Kolinski
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA and Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    Phys Rev Lett 112:134501. 2014
    ....
  38. pmc Physical basis for the adaptive flexibility of Bacillus spore coats
    Ozgur Sahin
    Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA
    J R Soc Interface 9:3156-60. 2012
    ..This characteristic of the spore and its coat may inspire design of adaptive materials...
  39. ncbi request reprint How the cucumber tendril coils and overwinds
    Sharon J Gerbode
    School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA
    Science 337:1087-91. 2012
    ..Collectively, our study illuminates the origin of tendril coiling, quantifies Darwin's original proposal, and suggests designs for biomimetic twistless springs with tunable mechanical responses...
  40. pmc Optimal vein density in artificial and real leaves
    X Noblin
    Department of Organismic and Evolutionary Biology, School of Engineering and Applied Sciences, and Arnold Arboretum, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 105:9140-4. 2008
    ....
  41. ncbi request reprint Soft lubrication
    J M Skotheim
    Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge CB3 0WA, United Kingdom
    Phys Rev Lett 92:245509. 2004
    ..Thus, they are relevant in the elastohydrodynamic lubrication of soft elastic and poroelastic gels and shells, and in the context of biolubrication in cartilaginous joints...
  42. ncbi request reprint Excitable patterns in active nematics
    L Giomi
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 106:218101. 2011
    ..In this regime the dynamics consists of nearly stationary periods separated by "bursts" of activity in which the system is elastically distorted and solvent is pumped throughout. At even higher activity, the dynamics becomes chaotic...
  43. ncbi request reprint Unfolding the sulcus
    Evan Hohlfeld
    Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 106:105702. 2011
    ..At intermediate strains the system is linearly stable but nonlinearly unstable with no energy barrier. Simple experiments confirm the existence of these two critical strains...
  44. doi request reprint Control of shape and size of nanopillar assembly by adhesion-mediated elastocapillary interaction
    Sung H Kang
    School of Engineering and Applied Sciences, Harvard University, 29 Oxford Street, Cambridge, Massachusetts 02138, United States
    ACS Nano 4:6323-31. 2010
    ..Our findings provide insight into how multiple parameters work together in capillary-induced self-assembly and provide us with a diverse set of options for fabricating a variety of nanostructures by self-assembly...
  45. ncbi request reprint Statistical mechanics of developable ribbons
    L Giomi
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 104:238104. 2010
    ..Our results are applicable to many ribbonlike objects in polymer physics and nanoscience that cannot be described by the classical wormlike chain model...
  46. doi request reprint Shape and dynamics of tip-growing cells
    Otger Campàs
    School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA
    Curr Biol 19:2102-7. 2009
    ..18]), fungi (hyphal growth [19, 20] and fission and budding yeast [3]), and some bacteria [21], in the context of both tip growth and diffuse growth...
  47. pmc The shape of a long leaf
    Haiyi Liang
    School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 106:22049-54. 2009
    ..Our theory delineates the geometric and growth control parameters that determine the shape space of finite laminae and thus allows for a comparative study of elongated leaf morphology...
  48. ncbi request reprint Statistical mechanics and shape transitions in microscopic plates
    Ee Hou Yong
    Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 112:048101. 2014
    ..Our results are applicable to objects such as graphene flakes or protein β sheets, where fluctuations, geometry, and finite size effects are important. ..
  49. doi request reprint Rationally designed complex, hierarchical microarchitectures
    Wim L Noorduin
    School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA
    Science 340:832-7. 2013
    ..These results outline a nanotechnology strategy for "collaborating" with self-assembly processes in real time to build arbitrary tectonic architectures...
  50. ncbi request reprint Geometric mechanics of periodic pleated origami
    Z Y Wei
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 110:215501. 2013
    ..Finally, we solve the inverse design problem of determining the geometric parameters for the optimal geometric and mechanical response of these extreme structures...
  51. ncbi request reprint Hydrodynamics of hemostasis in sickle-cell disease
    S I A Cohen
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 110:138104. 2013
    ....
  52. ncbi request reprint Surface sulci in squeezed soft solids
    T Tallinen
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 110:024302. 2013
    ..In contrast, highly compressible solids when squeezed show only one sulcified phase characterized by a hexagonal sulcus network...
  53. ncbi request reprint Slicing softly with shear
    E Reyssat
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 109:244301. 2012
    ..This transition between global and local deformations in soft solids as a function of the angle of shear explains the mechanics of the paper cut and design of guillotine blades...
  54. ncbi request reprint Skating on a film of air: drops impacting on a surface
    John M Kolinski
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 108:074503. 2012
    ..Our results show that the dynamics of impacting drops are much more complex than previously thought, with a rich array of unexpected phenomena that require rethinking classic paradigms...
  55. ncbi request reprint Mechanosensation and mechanical load modulate the locomotory gait of swimming C. elegans
    Jeremie Korta
    Department of Physics, Harvard University, Cambridge, MA 02138, USA
    J Exp Biol 210:2383-9. 2007
    ..The adaptability of locomotory gait in C. elegans may be encoded in sensory and motor systems that allow the worm to respond to its own movement in different physical surroundings...
  56. pmc Polymer science and biology: structure and dynamics at multiple scales
    L Mahadevan
    School of Engineering and Applied Sciences, Harvard University, Department of Systems Biology, Harvard Medical School, 29 Oxford St, Cambridge, MA 02138, USA
    Faraday Discuss 139:9-19; discussion 105-28, 419-20. 2008
    ..I give a brief, biased survey of some recent problems in molecular and cell biology from the perspective of physical science, with a few answers, but a great many questions, challenges and opportunities...
  57. ncbi request reprint Giomi and mahadevan reply:
    L Giomi
    School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
    Phys Rev Lett 107:239802. 2011
    ..A Reply to the Comment by E.L. Starostin and G.H.M. van der Heijden...
  58. pmc The elements of draping
    E Cerda
    Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Wilberforce Road, Cambridge CB3 0WA, United Kingdom
    Proc Natl Acad Sci U S A 101:1806-10. 2004
    ..Our results are consistent with commonplace observations of drapes and complement large-scale computations of draping by providing benchmarks. They also yield a qualitative guide to fashion design and virtual reality animation...
  59. pmc Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement
    Clifford P Brangwynne
    Department of Physics, Harvard University, Cambridge, MA 02138, USA
    J Cell Biol 173:733-41. 2006
    ....
  60. pmc Kinks, rings, and rackets in filamentous structures
    Adam E Cohen
    Semiconductor Physics Group, Cavendish Laboratory, Wilberforce Road, Cambridge University, Cambridge CB3 0WA, United Kingdom
    Proc Natl Acad Sci U S A 100:12141-6. 2003
    ..Our mesoscopic continuum theory is capable of quantifying observations of these structures and is suggestive of their occurrence in other filamentous assemblies as well...
  61. ncbi request reprint Geometry and physics of wrinkling
    E Cerda
    Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Silver Street, Cambridge CB3 9EW, United Kingdom
    Phys Rev Lett 90:074302. 2003
    ..These could form the basis of a highly sensitive quantitative wrinkling assay for the mechanical characterization of thin solid membranes...
  62. pmc Stored elastic energy powers the 60-microm extension of the Limulus polyphemus sperm actin bundle
    Jennifer H Shin
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    J Cell Biol 162:1183-8. 2003
    ....
  63. ncbi request reprint Modelling DNA loops using continuum and statistical mechanics
    A Balaeff
    Beckman Institute and Department of Physics, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Philos Transact A Math Phys Eng Sci 362:1355-71. 2004
    ..Finally, a combined Monte Carlo and Brownian dynamics solver for a worm-like chain model is described and a preliminary analysis of DNA loop-formation kinetics is presented...
  64. pmc Life and times of a cellular bleb
    Guillaume T Charras
    Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA
    Biophys J 94:1836-53. 2008
    ..Finally, using artificially nucleated blebs as pressure sensors, we show that cells rounded up in mitosis possess a substantial intracellular pressure...
  65. pmc Dynamics of chromatin decondensation reveals the structural integrity of a mechanically prestressed nucleus
    Aprotim Mazumder
    National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India
    Biophys J 95:3028-35. 2008
    ..Our experiments on decondensation of chromatin in nuclei suggest that its compaction is a critical parameter in controlling nuclear stability...
  66. ncbi request reprint The universal dynamics of cell spreading
    Damien Cuvelier
    Physical Chemistry Curie, UMR 168, Institut Curie, 75005 Paris, France
    Curr Biol 17:694-9. 2007
    ..Thus, although cell spreading is driven by well-identified biomolecular interactions, it is dynamically limited by its mesoscopic structure and material properties...
  67. ncbi request reprint Modeling DNA loops using the theory of elasticity
    Alexander Balaeff
    Beckman Institute, Center for Biophysics and Computational Biology, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 73:031919. 2006
    ..The scope and applications of the model in already accomplished and in future multi-scale studies of protein-DNA complexes are discussed...
  68. ncbi request reprint Superficial wrinkles in stretched, drying gelatin films
    R Rizzieri
    Polymers and Colloids Group, Physics Department, Cavendish Laboratory, University of Cambridge, Madingley Road, Cambridge CB3 0HE, UK
    Langmuir 22:3622-6. 2006
    ..We investigate these patterns via in situ environmental scanning electron microscopy (ESEM) and provide a theory for their origin...
  69. pmc How aphids lose their marbles
    Nathan Pike
    Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK
    Proc Biol Sci 269:1211-5. 2002
    ....
  70. ncbi request reprint How the Venus flytrap snaps
    Yoel Forterre
    IUSTI CNRS, Universite de Provence, 5 rue Enrico Fermi, 13453 Marseille Cedex 13, France
    Nature 433:421-5. 2005
    ..Our study identifies an ingenious solution to scaling up movements in non-muscular engines and provides a general framework for understanding nastic motion in plants...