B K Madras

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain
    B K Madras
    Department of Psychiatry, Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts 01772 9102, USA
    Synapse 29:93-104. 1998
  2. ncbi request reprint Altropane, a SPECT or PET imaging probe for dopamine neurons: II. Distribution to dopamine-rich regions of primate brain
    B K Madras
    Dept of Psychiatry, Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts 01772 9102, USA
    Synapse 29:105-15. 1998
  3. ncbi request reprint Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain
    B K Madras
    Department of Psychiatry, Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts 01772 9102, USA
    Synapse 29:116-27. 1998
  4. ncbi request reprint Nitrogen-based drugs are not essential for blockade of monoamine transporters
    B K Madras
    Department of Psychiatry, Harvard Medical School, NERPRC, Southborough, MA 01772 9102, USA
    Synapse 24:340-8. 1996
  5. ncbi request reprint Non-amines, drugs without an amine nitrogen, potently block serotonin transport: novel antidepressant candidates?
    M Goulet
    Harvard Medical School, Department of Psychiatry, Division of Neurochemistry, New England Regional Primate Research Center, Southborough, Massachusetts 01772 9102, USA
    Synapse 42:129-40. 2001
  6. ncbi request reprint Rapid detection of Parkinson's disease by SPECT with altropane: a selective ligand for dopamine transporters
    A J Fischman
    Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Synapse 29:128-41. 1998
  7. ncbi request reprint Single nucleotide polymorphisms distinguish multiple dopamine transporter alleles in primates: implications for association with attention deficit hyperactivity disorder and other neuropsychiatric disorders
    G M Miller
    Harvard Medical School, Division of Neurochemistry, New England Regional Primate Research Center, One Pine Hill Drive, Southborough, MA 01772-9102, USA
    Mol Psychiatry 6:50-8. 2001
  8. ncbi request reprint Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity
    G M Miller
    Harvard Medical School, Division of Neurochemistry, New England Regional Primate Research Center, One Pine Hill Drive, 01772, Southborough, MA, USA
    Brain Res Mol Brain Res 87:124-43. 2001
  9. ncbi request reprint Polymorphisms in the 3'-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression
    G M Miller
    Harvard Medical School, Division of Neurochemistry, New England Regional Primate Research Center, One Pine Hill Drive, Southborough, MA 01772 9102, USA
    Mol Psychiatry 7:44-55. 2002
  10. ncbi request reprint A mu-opioid receptor single nucleotide polymorphism in rhesus monkey: association with stress response and aggression
    G M Miller
    Division of Neurochemistry, New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA 01772 9102, USA
    Mol Psychiatry 9:99-108. 2004

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain
    B K Madras
    Department of Psychiatry, Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts 01772 9102, USA
    Synapse 29:93-104. 1998
    ....
  2. ncbi request reprint Altropane, a SPECT or PET imaging probe for dopamine neurons: II. Distribution to dopamine-rich regions of primate brain
    B K Madras
    Dept of Psychiatry, Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts 01772 9102, USA
    Synapse 29:105-15. 1998
    ..The selective binding of altropane to the dopamine-rich striatum within 30 min of i.v. administration indicates that it is uniquely suited for SPECT or PET imaging of the dopamine transporter and associated dopamine neurons...
  3. ncbi request reprint Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain
    B K Madras
    Department of Psychiatry, Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts 01772 9102, USA
    Synapse 29:116-27. 1998
    ....
  4. ncbi request reprint Nitrogen-based drugs are not essential for blockade of monoamine transporters
    B K Madras
    Department of Psychiatry, Harvard Medical School, NERPRC, Southborough, MA 01772 9102, USA
    Synapse 24:340-8. 1996
    ....
  5. ncbi request reprint Non-amines, drugs without an amine nitrogen, potently block serotonin transport: novel antidepressant candidates?
    M Goulet
    Harvard Medical School, Department of Psychiatry, Division of Neurochemistry, New England Regional Primate Research Center, Southborough, Massachusetts 01772 9102, USA
    Synapse 42:129-40. 2001
    ..Non-amines open avenues for developing a new generation of antidepressants...
  6. ncbi request reprint Rapid detection of Parkinson's disease by SPECT with altropane: a selective ligand for dopamine transporters
    A J Fischman
    Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Synapse 29:128-41. 1998
    ..The high selectivity and rapid striatal accumulation of the ligand allows for accurate quantitation of DAT sites in less than 2 hr. The results further demonstrate that [123I]altropane is an effective marker for PD...
  7. ncbi request reprint Single nucleotide polymorphisms distinguish multiple dopamine transporter alleles in primates: implications for association with attention deficit hyperactivity disorder and other neuropsychiatric disorders
    G M Miller
    Harvard Medical School, Division of Neurochemistry, New England Regional Primate Research Center, One Pine Hill Drive, Southborough, MA 01772-9102, USA
    Mol Psychiatry 6:50-8. 2001
    ....
  8. ncbi request reprint Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity
    G M Miller
    Harvard Medical School, Division of Neurochemistry, New England Regional Primate Research Center, One Pine Hill Drive, 01772, Southborough, MA, USA
    Brain Res Mol Brain Res 87:124-43. 2001
    ....
  9. ncbi request reprint Polymorphisms in the 3'-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression
    G M Miller
    Harvard Medical School, Division of Neurochemistry, New England Regional Primate Research Center, One Pine Hill Drive, Southborough, MA 01772 9102, USA
    Mol Psychiatry 7:44-55. 2002
    ..This report provides experimental evidence that variability in the length or the sequence of the 3'-UTR of the DAT gene may influence levels of DAT protein in the brain...
  10. ncbi request reprint A mu-opioid receptor single nucleotide polymorphism in rhesus monkey: association with stress response and aggression
    G M Miller
    Division of Neurochemistry, New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA 01772 9102, USA
    Mol Psychiatry 9:99-108. 2004
    ..The data support the use of nonhuman primates to investigate mu-opioid receptor genotype/phenotype relations of relevance to humans...