G MacBeath

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc A system-wide investigation of the dynamics of Wnt signaling reveals novel phases of transcriptional regulation
    Taranjit S Gujral
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
    PLoS ONE 5:e10024. 2010
  2. pmc High- and low-affinity epidermal growth factor receptor-ligand interactions activate distinct signaling pathways
    Jordan A Krall
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
    PLoS ONE 6:e15945. 2011
  3. ncbi request reprint Printing proteins as microarrays for high-throughput function determination
    G MacBeath
    Center for Genomics Research, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Science 289:1760-3. 2000
  4. pmc Chemical genomics: what will it take and who gets to play?
    G MacBeath
    Center for Genomics Research, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Genome Biol 2:COMMENT2005. 2001

Collaborators

Detail Information

Publications4

  1. pmc A system-wide investigation of the dynamics of Wnt signaling reveals novel phases of transcriptional regulation
    Taranjit S Gujral
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
    PLoS ONE 5:e10024. 2010
    ..05). Our data highlight CtBP1 as a transcription factor that contributes to positive feedback during the early phases of Wnt signaling and serves as a novel marker for colorectal cancer progression...
  2. pmc High- and low-affinity epidermal growth factor receptor-ligand interactions activate distinct signaling pathways
    Jordan A Krall
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
    PLoS ONE 6:e15945. 2011
    ..The existence of receptors with distinct signaling properties provides a way for EGFR to respond to different concentrations of the same ligand in qualitatively different ways...
  3. ncbi request reprint Printing proteins as microarrays for high-throughput function determination
    G MacBeath
    Center for Genomics Research, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Science 289:1760-3. 2000
    ..Three applications for protein microarrays were demonstrated: screening for protein-protein interactions, identifying the substrates of protein kinases, and identifying the protein targets of small molecules...
  4. pmc Chemical genomics: what will it take and who gets to play?
    G MacBeath
    Center for Genomics Research, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Genome Biol 2:COMMENT2005. 2001
    ..Although innovation in each of these areas can come from individual academic labs, it will require large, well-funded centers to integrate these components and freely distribute both data and reagents...