Jose R Lopez

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Altered Ca2+ homeostasis in human uremic skeletal muscle: possible involvement of cADPR in elevation of intracellular resting [Ca2+]
    Jose R Lopez
    Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    Nephron Physiol 100:p51-60. 2005
  2. ncbi Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i
    Jose R Lopez
    Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    Am J Physiol Cell Physiol 288:C606-12. 2005
  3. doi Dysfunction of diastolic [ca(2+)] in cardiomyocytes isolated from chagasic patients
    Jose R Lopez
    Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela Department of Anesthesiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States
    Rev Esp Cardiol (Engl Ed) 64:456-62. 2011
  4. doi [Dysfunction of diastolic [Ca²⁺] in cardiomyocytes isolated from chagasic patients]
    Jose R Lopez
    Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    Rev Esp Cardiol 64:456-62. 2011
  5. ncbi Ca2+ influx through alpha1S DHPR may play a role in regulating Ca2+ release from RyR1 in skeletal muscle
    Alexander Shtifman
    Department of Anesthesia Research, Brigham and Women s Hospital, Harvard Medical School, 20 Shattuck Street, Boston, MA 02115, USA
    Am J Physiol Cell Physiol 286:C73-8. 2004
  6. ncbi Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle
    Claudio F Perez
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, 20 Shattuck St, Rm SR 153, Boston, MA 02115, USA
    Am J Physiol Cell Physiol 288:C640-9. 2005
  7. pmc Age-dependent changes in diastolic Ca(2+) and Na(+) concentrations in dystrophic cardiomyopathy: Role of Ca(2+) entry and IP3
    Alfredo Mijares
    Instituto Venezolano de Investigaciones Cientificas, Centro de Biofisica y Bioquimica, Caracas, Venezuela
    Biochem Biophys Res Commun 452:1054-9. 2014
  8. pmc Evidence of reversible bradycardia and arrhythmias caused by immunogenic proteins secreted by T. cruzi in isolated rat hearts
    Héctor O Rodríguez-Angulo
    Laboratorio de Fisiología de Parásitos, Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    PLoS Negl Trop Dis 9:e0003512. 2015

Collaborators

Detail Information

Publications8

  1. ncbi Altered Ca2+ homeostasis in human uremic skeletal muscle: possible involvement of cADPR in elevation of intracellular resting [Ca2+]
    Jose R Lopez
    Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    Nephron Physiol 100:p51-60. 2005
    ..The current study investigated the possible role of cADPR in uremic myopathy...
  2. ncbi Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i
    Jose R Lopez
    Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    Am J Physiol Cell Physiol 288:C606-12. 2005
    ..These results suggest that the differences in the response of MHS skeletal myoballs to caffeine and 4-CmC may be mediated at least in part by the chronic high resting [Ca(2+)](i) levels in these cells...
  3. doi Dysfunction of diastolic [ca(2+)] in cardiomyocytes isolated from chagasic patients
    Jose R Lopez
    Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela Department of Anesthesiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States
    Rev Esp Cardiol (Engl Ed) 64:456-62. 2011
    ..We have studied the regulation of intracellular calcium in cardiomyocytes isolated from chagasic patients with different degrees of heart dysfunction...
  4. doi [Dysfunction of diastolic [Ca²⁺] in cardiomyocytes isolated from chagasic patients]
    Jose R Lopez
    Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    Rev Esp Cardiol 64:456-62. 2011
    ..We have studied the regulation of intracellular calcium in cardiomyocytes isolated from chagasic patients with different degrees of heart dysfunction...
  5. ncbi Ca2+ influx through alpha1S DHPR may play a role in regulating Ca2+ release from RyR1 in skeletal muscle
    Alexander Shtifman
    Department of Anesthesia Research, Brigham and Women s Hospital, Harvard Medical School, 20 Shattuck Street, Boston, MA 02115, USA
    Am J Physiol Cell Physiol 286:C73-8. 2004
    ....
  6. ncbi Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle
    Claudio F Perez
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, 20 Shattuck St, Rm SR 153, Boston, MA 02115, USA
    Am J Physiol Cell Physiol 288:C640-9. 2005
    ..These data suggest that the coexpression of RyR1 and RyR3 at different levels may constitute a novel mechanism by which to regulate [Ca(2+)](r) in skeletal muscle...
  7. pmc Age-dependent changes in diastolic Ca(2+) and Na(+) concentrations in dystrophic cardiomyopathy: Role of Ca(2+) entry and IP3
    Alfredo Mijares
    Instituto Venezolano de Investigaciones Cientificas, Centro de Biofisica y Bioquimica, Caracas, Venezuela
    Biochem Biophys Res Commun 452:1054-9. 2014
    ....
  8. pmc Evidence of reversible bradycardia and arrhythmias caused by immunogenic proteins secreted by T. cruzi in isolated rat hearts
    Héctor O Rodríguez-Angulo
    Laboratorio de Fisiología de Parásitos, Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    PLoS Negl Trop Dis 9:e0003512. 2015
    ..Arrhythmias have been related to sudden death, even in asymptomatic patients, and their molecular mechanisms have not been fully elucidated...