Simin Liu

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management
    Lin Wang
    Program for Population Genetics, Harvard School of Public Health, Boston, MA 02115, USA
    BMC Bioinformatics 6:60. 2005
  2. ncbi request reprint Dietary glycemic load and atherothrombotic risk
    Simin Liu
    Division of Preventive Medicine, Harvard Medical School and Brigham and Women s Hospital, 900 Commonwealth Avenue, Boston, MA 02215, USA
    Curr Atheroscler Rep 4:454-61. 2002
  3. ncbi request reprint A prospective study of the APOA1 XmnI and APOC3 SstI polymorphisms in the APOA1/C3/A4 gene cluster and risk of incident myocardial infarction in men
    Simin Liu
    Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Atherosclerosis 177:119-26. 2004
  4. ncbi request reprint Intake of refined carbohydrates and whole grain foods in relation to risk of type 2 diabetes mellitus and coronary heart disease
    Simin Liu
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard School of Medicine, Boston, Massachusetts 02115, USA
    J Am Coll Nutr 21:298-306. 2002
  5. ncbi request reprint Relation between a diet with a high glycemic load and plasma concentrations of high-sensitivity C-reactive protein in middle-aged women
    Simin Liu
    Center of Cardiovascular Prevention, the Division of Preventive Medicine, Harvard Medical School, Boston 02215, USA
    Am J Clin Nutr 75:492-8. 2002
  6. ncbi request reprint Dietary carbohydrates, physical inactivity, obesity, and the 'metabolic syndrome' as predictors of coronary heart disease
    S Liu
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA
    Curr Opin Lipidol 12:395-404. 2001
  7. pmc Dietary glycemic index, dietary glycemic load, blood lipids, and C-reactive protein
    Emily B Levitan
    Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Metabolism 57:437-43. 2008
  8. ncbi request reprint Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women
    Yiqing Song
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Diabetes Care 28:1438-44. 2005
  9. pmc Sex hormone-binding globulin and risk of type 2 diabetes in women and men
    Eric L Ding
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    N Engl J Med 361:1152-63. 2009
  10. pmc Dietary glycemic load, glycemic index, and carbohydrate and risk of breast cancer in the Women's Health Initiative
    James M Shikany
    Division of Preventive Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham Alabama 35294, USA
    Nutr Cancer 63:899-907. 2011

Collaborators

Detail Information

Publications111 found, 100 shown here

  1. pmc SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management
    Lin Wang
    Program for Population Genetics, Harvard School of Public Health, Boston, MA 02115, USA
    BMC Bioinformatics 6:60. 2005
    ..Selection and retrieval of an optimal SNP set from publicly available databases have emerged as the foremost bottlenecks in designing large-scale linkage disequilibrium studies, particularly in case-control settings...
  2. ncbi request reprint Dietary glycemic load and atherothrombotic risk
    Simin Liu
    Division of Preventive Medicine, Harvard Medical School and Brigham and Women s Hospital, 900 Commonwealth Avenue, Boston, MA 02215, USA
    Curr Atheroscler Rep 4:454-61. 2002
    ....
  3. ncbi request reprint A prospective study of the APOA1 XmnI and APOC3 SstI polymorphisms in the APOA1/C3/A4 gene cluster and risk of incident myocardial infarction in men
    Simin Liu
    Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Atherosclerosis 177:119-26. 2004
    ..However, whether genetic variations in the APOA1/C3/A4 gene cluster are associated with the risk of myocardial infarction (MI) remains uncertain and prospective data are sparse...
  4. ncbi request reprint Intake of refined carbohydrates and whole grain foods in relation to risk of type 2 diabetes mellitus and coronary heart disease
    Simin Liu
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard School of Medicine, Boston, Massachusetts 02115, USA
    J Am Coll Nutr 21:298-306. 2002
    ..It seems prudent, therefore, to distinguish whole-grain rather than refined-grain cereal products for the prevention of chronic diseases...
  5. ncbi request reprint Relation between a diet with a high glycemic load and plasma concentrations of high-sensitivity C-reactive protein in middle-aged women
    Simin Liu
    Center of Cardiovascular Prevention, the Division of Preventive Medicine, Harvard Medical School, Boston 02215, USA
    Am J Clin Nutr 75:492-8. 2002
    ..Recent prospective data suggest that intake of rapidly digested and absorbed carbohydrates with a high dietary glycemic load is associated with an increased risk of ischemic heart disease...
  6. ncbi request reprint Dietary carbohydrates, physical inactivity, obesity, and the 'metabolic syndrome' as predictors of coronary heart disease
    S Liu
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA
    Curr Opin Lipidol 12:395-404. 2001
    ....
  7. pmc Dietary glycemic index, dietary glycemic load, blood lipids, and C-reactive protein
    Emily B Levitan
    Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Metabolism 57:437-43. 2008
    ..24, and TG = 13 mg/dL). Differences in blood lipids and CRP between extreme quintiles of dietary GI and GL were small, but may translate into a clinically meaningful difference in cardiovascular risk...
  8. ncbi request reprint Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women
    Yiqing Song
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Diabetes Care 28:1438-44. 2005
    ..The aim of this study was to examine whether and to what extent magnesium intake is related to systemic inflammation and the metabolic syndrome...
  9. pmc Sex hormone-binding globulin and risk of type 2 diabetes in women and men
    Eric L Ding
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    N Engl J Med 361:1152-63. 2009
    ..Circulating sex hormone-binding globulin levels are inversely associated with insulin resistance, but whether these levels can predict the risk of developing type 2 diabetes is uncertain...
  10. pmc Dietary glycemic load, glycemic index, and carbohydrate and risk of breast cancer in the Women's Health Initiative
    James M Shikany
    Division of Preventive Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham Alabama 35294, USA
    Nutr Cancer 63:899-907. 2011
    ..07). Although there was no evidence of associations between GL, GI, or carbohydrate and total breast cancer risk in WHI participants, the suggestion of an association between GL and risk of in situ cancers requires further investigation...
  11. ncbi request reprint The association between magnesium intake and fasting insulin concentration in healthy middle-aged women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02215, USA
    J Am Coll Nutr 22:533-8. 2003
    ..We assessed the association between magnesium intake and fasting insulin levels in a large cohort of women...
  12. pmc FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 16:2472-80. 2008
    ..In conclusion, common genetic variants in the intron 1 of FTO gene may confer a modest susceptibility to obesity in an ethnicity-specific manner, but may be unlikely to contribute to a clinically significant diabetes risk...
  13. pmc Plasma adiponectin and the risk of hypertension in white and black postmenopausal women
    Lu Wang
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Clin Chem 58:1438-45. 2012
    ..We conducted a prospective, nested case control study to investigate the relation between baseline plasma adiponectin, measures of adiposity, and subsequent risk of hypertension...
  14. ncbi request reprint Low-carbohydrate-diet score and the risk of coronary heart disease in women
    Thomas L Halton
    Departments of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 355:1991-2002. 2006
    ..Low-carbohydrate diets have been advocated for weight loss and to prevent obesity, but the long-term safety of these diets has not been determined...
  15. pmc Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study
    William G Christen
    Divisions of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Arch Ophthalmol 126:102-9. 2008
    ..To examine in prospective data the relation between dietary intake of carotenoids and vitamins C and E and the risk of cataract in women...
  16. pmc Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in women
    Yiqing Song
    Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMC Med Genet 10:4. 2009
    ..However, it is unclear whether common genetic variation in TRPM6 and TRPM7 contributes to risk of type 2 diabetes...
  17. pmc Relation of genetic variation in the gene coding for C-reactive protein with its plasma protein concentrations: findings from the Women's Health Initiative Observational Cohort
    Cathy C Lee
    Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA
    Clin Chem 55:351-60. 2009
    ....
  18. pmc Circulating inflammatory and endothelial markers and risk of hypertension in white and black postmenopausal women
    Lu Wang
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Clin Chem 57:729-36. 2011
    ..However, epidemiologic studies have yet to compare multiple corresponding biomarkers in relation to risk of hypertension, particularly in multiethnic populations...
  19. ncbi request reprint Associations of dietary flavonoids with risk of type 2 diabetes, and markers of insulin resistance and systemic inflammation in women: a prospective study and cross-sectional analysis
    Yiqing Song
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    J Am Coll Nutr 24:376-84. 2005
    ..The aim of the present study was to examine the association of dietary flavonol and flavone intake with type 2 diabetes, and biomarkers of insulin resistance and systemic inflammation...
  20. ncbi request reprint Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women
    Simin Liu
    Division of Preventive Medicine and the Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 78:920-7. 2003
    ..Although increased consumption of dietary fiber and grain products is widely recommended to maintain healthy body weight, little is known about the relation of whole grains to body weight and long-term weight changes...
  21. ncbi request reprint Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort
    Nicola M McKeown
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Diabetes Care 27:538-46. 2004
    ..The aim of this study was to examine the relation between carbohydrate-related dietary factors, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort...
  22. ncbi request reprint Plasma lycopene, other carotenoids, and the risk of type 2 diabetes in women
    Lu Wang
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Am J Epidemiol 164:576-85. 2006
    ..91 (95% CI: 0.46, 1.81) for beta-cryptoxanthin, and 1.35 (95% CI: 0.68, 2.69) for lutein/zeaxanthin. There was no prospective association between baseline plasma carotenoids and the risk of type 2 diabetes in middle-aged and older women...
  23. ncbi request reprint Dietary glycemic index, glycemic load, cereal fiber, and plasma adiponectin concentration in diabetic men
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Diabetes Care 28:1022-8. 2005
    ..Adiponectin may improve insulin sensitivity, reduce inflammation, and ameliorate glycemic control. However, few studies have evaluated dietary predictors of plasma adiponectin levels, especially among subjects with type 2 diabetes...
  24. ncbi request reprint Genetic variation at the adiponectin locus and risk of type 2 diabetes in women
    Frank B Hu
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Diabetes 53:209-13. 2004
    ..03-2.08, P = 0.03). These data suggest a potential interaction between the adiponectin genotype and PPAR gamma genotype or obesity, but these analyses should be considered exploratory and require further investigation in larger studies...
  25. ncbi request reprint Dietary intake of whole and refined grain breakfast cereals and weight gain in men
    Lydia A Bazzano
    Department of Medicine, Beth Israel Deaconess Hospital, Boston, Massachusetts, USA
    Obes Res 13:1952-60. 2005
    ..The aim of this study was to prospectively assess the association between whole and refined grain breakfast cereal intakes and risk of overweight (BMI >or= 25 kg/m(2)) and weight gain...
  26. ncbi request reprint Dietary fibers and glycemic load, obesity, and plasma adiponectin levels in women with type 2 diabetes
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Diabetes Care 29:1501-5. 2006
    ..The purpose of this study was to examine the associations of dietary fibers and glycemic load with plasma adiponectin in diabetic women and investigate the modification effect of obesity...
  27. ncbi request reprint Whole- and refined-grain intakes and the risk of hypertension in women
    Lu Wang
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Am J Clin Nutr 86:472-9. 2007
    ..Prospective studies linking whole- and refined-grain intakes with the risk of hypertension, a major cardiovascular disease risk factor, remain limited...
  28. pmc Low-carbohydrate-diet score and risk of type 2 diabetes in women
    Thomas L Halton
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02215, USA
    Am J Clin Nutr 87:339-46. 2008
    ..Low-carbohydrate weight-loss diets remain popular; however, the long-term effects of these diets are not known...
  29. ncbi request reprint A prospective study of dairy intake and the risk of type 2 diabetes in women
    Simin Liu
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Diabetes Care 29:1579-84. 2006
    ..Although studies have indicated that increased dairy intake may reduce risk of overweight and insulin resistance syndrome, data directly relating dairy intake to type 2 diabetes remain sparse...
  30. pmc Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of women
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 56:1898-904. 2007
    ..S. postmenopausal women, implicating an etiological role of endothelial dysfunction in the pathogenesis of type 2 diabetes...
  31. ncbi request reprint Dietary magnesium intake in relation to plasma insulin levels and risk of type 2 diabetes in women
    Yiqing Song
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Diabetes Care 27:59-65. 2004
    ..Higher intake of magnesium appears to improve glucose and insulin homeostasis; however, there are sparse prospective data on the association between magnesium intake and incidence of type 2 diabetes...
  32. ncbi request reprint Magnesium intake and risk of type 2 diabetes in men and women
    Ruy Lopez-Ridaura
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02215, USA
    Diabetes Care 27:134-40. 2004
    ..To examine the association between magnesium intake and risk of type 2 diabetes...
  33. ncbi request reprint Potato and french fry consumption and risk of type 2 diabetes in women
    Thomas L Halton
    Department of Nutrition and Epidemiology, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02215, USA
    Am J Clin Nutr 83:284-90. 2006
    ..Potatoes, a high glycemic form of carbohydrate, are hypothesized to increase insulin resistance and risk of type 2 diabetes...
  34. ncbi request reprint Carbohydrate intake, glycemic index, glycemic load, and dietary fiber in relation to risk of stroke in women
    Kyungwon Oh
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 161:161-9. 2005
    ..In addition, high consumption of cereal fiber was associated with lower risk of total and hemorrhagic stroke...
  35. ncbi request reprint Glycemic index, glycemic load, and dietary fiber intake and incidence of type 2 diabetes in younger and middle-aged women
    Matthias B Schulze
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Am J Clin Nutr 80:348-56. 2004
    ..Increasing evidence suggests an important role of carbohydrate quality in the development of type 2 diabetes...
  36. ncbi request reprint A prospective study of fruit and vegetable intake and the risk of type 2 diabetes in women
    Simin Liu
    Division of Preventive Medicine, Brigham Women s Hospital, 900 Commonwealth Ave East, Boston, MA 02215, USA
    Diabetes Care 27:2993-6. 2004
  37. doi request reprint Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study
    Yi Hsiang Hsu
    Institute for Aging Research, Hebrew Senior Life and Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 57:1101-7. 2008
    ..Genetic variants in the UCP2-UCP3 gene cluster, located on chromosome 11q13, may play a significant role in the development of type 2 diabetes...
  38. ncbi request reprint Common genetic variation in calpain-10 gene (CAPN10) and diabetes risk in a multi-ethnic cohort of American postmenopausal women
    Yiqing Song
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Hum Mol Genet 16:2960-71. 2007
    ..37 for haplotypes in block 2). In conclusion, we did not observe any significant associations of the common SNPs or haplotypes across the CAPN10 gene with diabetes risk in our large and ethnically diverse cohort of postmenopausal women...
  39. pmc Insulin sensitivity and insulin secretion determined by homeostasis model assessment and risk of diabetes in a multiethnic cohort of women: the Women's Health Initiative Observational Study
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Diabetes Care 30:1747-52. 2007
    ..However, prospective data regarding its relation to diabetes risk in ethnically diverse populations are limited...
  40. ncbi request reprint Dietary magnesium intake and risk of incident hypertension among middle-aged and older US women in a 10-year follow-up study
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am J Cardiol 98:1616-21. 2006
    ..In conclusion, the results suggest that higher intake of dietary magnesium may have a modest effect on the development of hypertension in women...
  41. ncbi request reprint Whole-grain, bran, and cereal fiber intakes and markers of systemic inflammation in diabetic women
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Diabetes Care 29:207-11. 2006
    ..To evaluate the dietary predictors for the markers of systemic inflammation and endothelial dysfunction in patients with type 2 diabetes...
  42. ncbi request reprint Insulin, proinsulin, proinsulin:insulin ratio, and the risk of developing type 2 diabetes mellitus in women
    Aruna D Pradhan
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Med 114:438-44. 2003
    ..To assess the associations among baseline levels of fasting insulin and proinsulin, proinsulin:insulin ratio, and the development of type 2 diabetes mellitus in apparently healthy middle-aged women...
  43. ncbi request reprint Dietary calcium, vitamin D, and the prevalence of metabolic syndrome in middle-aged and older U.S. women
    Simin Liu
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Diabetes Care 28:2926-32. 2005
    ..To examine whether and to what extent intakes of calcium and vitamin D are related to the metabolic syndrome in middle-aged or older women...
  44. pmc Elevated depressive symptoms, antidepressant use, and diabetes in a large multiethnic national sample of postmenopausal women
    Yunsheng Ma
    Division of Preventive and Behavioral Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Diabetes Care 34:2390-2. 2011
    ..To examine elevated depressive symptoms and antidepressant use in relation to diabetes incidence in the Women's Health Initiative...
  45. ncbi request reprint Dietary magnesium intake and risk of cardiovascular disease among women
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 96:1135-41. 2005
    ..In conclusion, the results do not support the hypothesis that magnesium intake reduces the development of CHD, although a modest inverse association with stroke cannot be ruled out...
  46. ncbi request reprint Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus
    Cuilin Zhang
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Diabetes Care 29:2223-30. 2006
    ..We aimed to examine whether pregravid dietary fiber consumptions from cereal, fruit, and vegetable sources and dietary glycemic load were related to gestational diabetes mellitus (GDM) risk...
  47. ncbi request reprint Vitamin E and risk of type 2 diabetes in the women's health study randomized controlled trial
    Simin Liu
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Diabetes 55:2856-62. 2006
    ..83-1.04) (P = 0.21) compared with those randomized to placebo. In this large trial with 10-year follow-up, alternate-day doses of 600 IU vitamin E provided no significant benefit for type 2 diabetes in initially healthy women...
  48. ncbi request reprint The consumption of lycopene and tomato-based food products is not associated with the risk of type 2 diabetes in women
    Lu Wang
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    J Nutr 136:620-5. 2006
    ..Our study found little evidence for an association between dietary intake of lycopene or lycopene-containing foods and the risk of type 2 DM...
  49. ncbi request reprint A prospective study of red meat consumption and type 2 diabetes in middle-aged and elderly women: the women's health study
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, BrighamWomen s Hospital, Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215, USA
    Diabetes Care 27:2108-15. 2004
    ..The aim of this study was to prospectively assess the relation between red meat intake and incidence of type 2 diabetes...
  50. ncbi request reprint Dietary glycemic load, carbohydrate, sugar, and colorectal cancer risk in men and women
    Dominique S Michaud
    Harvard School of Public Health, Kresge 920, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:138-47. 2005
    ..High intakes of GL, fructose, and sucrose were related to an elevated colorectal cancer risk among men. For women, however, these factors did not seem to increase the risk of colorectal cancer...
  51. ncbi request reprint Dietary carbohydrates, fiber, and breast cancer risk
    Michelle D Holmes
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Am J Epidemiol 159:732-9. 2004
    ..This study also confirmed the lack of an overall association between intake of fiber and fiber types and breast cancer risk observed in other prospective studies...
  52. ncbi request reprint Types of carbohydrates and risk of cardiovascular disease
    Mark A Pereira
    Department of Pediatrics, Harvard Medical School and Children s Hospital, Boston, Massachusetts 02115, USA
    J Womens Health (Larchmt) 12:115-22. 2003
    ..More long-term controlled trials are needed to improve our understanding of efficacy and mechanisms. Women and a variety of racial/ethnic groups should be represented in these studies whenever possible...
  53. ncbi request reprint Is intake of breakfast cereals related to total and cause-specific mortality in men?
    Simin Liu
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 77:594-9. 2003
    ..Although breakfast cereals are a major source of whole and refined grains, little is known about their direct association with the risk of premature mortality...
  54. pmc Determinants of racial/ethnic disparities in incidence of diabetes in postmenopausal women in the U.S.: The Women's Health Initiative 1993-2009
    Yunsheng Ma
    Division of Preventive and Behavioral Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Diabetes Care 35:2226-34. 2012
    ..To examine determinants of racial/ethnic differences in diabetes incidence among postmenopausal women participating in the Women's Health Initiative...
  55. ncbi request reprint A prospective study of sugar intake and risk of type 2 diabetes in women
    Sok Ja Janket
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 26:1008-15. 2003
    ..The contribution of sugar intake to the pathogenesis of type 2 diabetes has not been settled in the context of primary prevention because of limited prospective data...
  56. pmc Comparison of usefulness of body mass index versus metabolic risk factors in predicting 10-year risk of cardiovascular events in women
    Yiqing Song
    Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 100:1654-8. 2007
    ..In conclusion, MS may largely account for the increased risk of CVD associated with BMI in apparently healthy women...
  57. ncbi request reprint A prospective study of the association between APOE genotype and the risk of myocardial infarction among apparently healthy men
    Simin Liu
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Atherosclerosis 166:323-9. 2003
    ..Apolipoprotein E (apoE) plays an important role in lipid metabolism. Three common alleles in the APOE gene, E2/E3/E4, have been associated with lipoprotein disorders but their effects on myocardial infarction (MI) risk remain uncertain...
  58. ncbi request reprint Nut and peanut butter consumption and risk of type 2 diabetes in women
    Rui Jiang
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    JAMA 288:2554-60. 2002
    ..Nuts are high in unsaturated (polyunsaturated and monounsaturated) fat and other nutrients that may improve glucose and insulin homeostasis...
  59. ncbi request reprint Whole-grain intake and the risk of type 2 diabetes: a prospective study in men
    Teresa T Fung
    Programs in Nutrition, Simmons College, Boston, MA 02115, USA
    Am J Clin Nutr 76:535-40. 2002
    ..Certain dietary components may play a role in the prevention of type 2 diabetes...
  60. ncbi request reprint Prevention of type 2 diabetes by diet and lifestyle modification
    Lydia A Bazzano
    Department of Medicine, Beth Israel Deaconess Hospital, Boston, MA 02215, USA
    J Am Coll Nutr 24:310-9. 2005
    ..Prevention of this devastating disease calls for the identification of culture-sensitive measures that can be applied to the population in general and some high-risk minority groups in particular...
  61. ncbi request reprint Prediagnostic plasma C-peptide and pancreatic cancer risk in men and women
    Dominique S Michaud
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:2101-9. 2007
    ..An association between serum insulin levels and pancreatic cancer risk was reported in a recent study, but the population was composed of heavy smokers and their findings may not be generalizable to nonsmokers...
  62. pmc Effects of a low-fat dietary intervention on glucose, insulin, and insulin resistance in the Women's Health Initiative (WHI) Dietary Modification trial
    James M Shikany
    Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Clin Nutr 94:75-85. 2011
    ..Glycemic effects of the Women's Health Initiative (WHI) low-fat dietary intervention are unknown...
  63. ncbi request reprint Prospective study of dietary carbohydrates, glycemic index, glycemic load, and incidence of type 2 diabetes mellitus in middle-aged Chinese women
    Raquel Villegas
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, 2525 West End Ave, Ste 600, Nashville, TN 37203 1738, USA
    Arch Intern Med 167:2310-6. 2007
    ..Much uncertainty exists about the role of dietary glycemic index and glycemic load in the development of type 2 diabetes mellitus, especially in populations that traditionally subsist on a diet high in carbohydrates...
  64. ncbi request reprint Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study
    Nicola M McKeown
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:390-8. 2002
    ..The influence of whole grains on cardiovascular disease risk may be mediated through multiple pathways, eg, a reduction in blood lipids and blood pressure, an enhancement of insulin sensitivity, and an improvement in blood glucose control...
  65. pmc Asthma, chronic obstructive pulmonary disease, and type 2 diabetes in the Women's Health Study
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Diabetes Res Clin Pract 90:365-71. 2010
    ..Chronic airway inflammation in asthma or chronic obstructive pulmonary disease (COPD) may be involved in the pathogenesis of type 2 diabetes; however, prospective data have been limited...
  66. ncbi request reprint Dietary intakes of fruit, vegetables, and fiber, and risk of colorectal cancer in a prospective cohort of women (United States)
    Jennifer Lin
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Cancer Causes Control 16:225-33. 2005
    ..We prospectively examined the association between dietary intakes of fruit, vegetables, and fiber and colorectal cancer risk in a large female cohort from the Women's Health Study...
  67. ncbi request reprint Association between consumption of beer, wine, and liquor and plasma concentration of high-sensitivity C-reactive protein in women aged 39 to 89 years
    Emily B Levitan
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 96:83-8. 2005
    ..09 mg/L (p = 0.43). The association between alcohol and hs-CRP concentration appears to be mediated primarily by ethanol and was independent of the type of alcoholic beverage consumed once BMI was taken into account...
  68. ncbi request reprint Dietary intake of fruits and vegetables and risk of cardiovascular disease
    Lydia A Bazzano
    Division of Preventive Medicine, Harvard Medical School and Brigham and Women s Hospital, 900 Commonwealth Avenue, Boston, MA 02215, USA
    Curr Atheroscler Rep 5:492-9. 2003
    ....
  69. ncbi request reprint A prospective study of TaqIB polymorphism in the gene coding for cholesteryl ester transfer protein and risk of myocardial infarction in middle-aged men
    Simin Liu
    Division of Preventive Medicine, Department of Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Atherosclerosis 161:469-74. 2002
    ..However, whether this polymorphism is associated with risk of myocardial infarction (MI) is uncertain...
  70. pmc Association of glycemic load with cardiovascular disease risk factors: the Women's Health Initiative Observational Study
    James M Shikany
    Division of Preventive Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA
    Nutrition 26:641-7. 2010
    ....
  71. ncbi request reprint Reproducibility and validity of dietary glycemic index, dietary glycemic load, and total carbohydrate intake in 141 Swedish men
    Emily B Levitan
    Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Am J Clin Nutr 85:548-53. 2007
    ....
  72. pmc Maternal dietary glycemic intake and the risk of neural tube defects
    Mahsa M Yazdy
    Slone Epidemiology Center, Boston University, Boston, MA02215, USA
    Am J Epidemiol 171:407-14. 2010
    ..0); for high DGL, it was 1.8 (95% confidence interval: 0.8, 4.0). Diets with proportionally high DGI or DGL may put the developing fetus at risk of an NTD, adding further evidence that hyperglycemia lies within the pathogenic pathway...
  73. ncbi request reprint Glycemic index, glycemic load, and risk of type 2 diabetes
    Walter Willett
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 76:274S-80S. 2002
    ....
  74. pmc Association between dietary fiber and markers of systemic inflammation in the Women's Health Initiative Observational Study
    Yunsheng Ma
    Division of Preventive and Behavioral Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Nutrition 24:941-9. 2008
    ....
  75. ncbi request reprint Fruit and vegetable intake and the risk of cataract in women
    William G Christen
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 81:1417-22. 2005
    ..Prospective data on cataract in relation to total fruit and vegetable intake are limited...
  76. ncbi request reprint Associations of the apolipoprotein A1/C3/A4/A5 gene cluster with triglyceride and HDL cholesterol levels in women with type 2 diabetes
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, United States
    Atherosclerosis 192:204-10. 2007
    ..006), whereas APOA4 +347T/A showed significant associations with lower levels of HDL-C (P=0.017). Our results indicate that the variability in APOA1/C3/A4/A5 gene cluster may affect TG and HDL levels in women with type 2 diabetes...
  77. ncbi request reprint Flavonoid intake and the risk of cardiovascular disease in women
    Howard D Sesso
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 77:1400-8. 2003
    ..Despite emerging evidence of the role of flavonoids in cardiovascular disease (CVD) prevention, the association remains unclear...
  78. pmc Are variants in the CAPN10 gene related to risk of type 2 diabetes? A quantitative assessment of population and family-based association studies
    Yiqing Song
    Division of Preventive Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02215, USA
    Am J Hum Genet 74:208-22. 2004
    ..Our findings also suggest that both large-scale, well-designed association studies and functional studies are warranted to either reliably confirm or conclusively refute the initial hypothesis regarding the role of CAPN10 in T2D risk...
  79. ncbi request reprint Dietary lycopene, tomato-based food products and cardiovascular disease in women
    Howard D Sesso
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    J Nutr 133:2336-41. 2003
    ....
  80. ncbi request reprint Antibodies capable of releasing diphtheria toxin in response to the low pH found in endosomes
    V Raso
    Boston Biomedical Research Institute, Boston, Massachusetts 02114, USA
    J Biol Chem 272:27618-22. 1997
    ..0 than at neutral pH. This novel acid-triggered release mechanism provides a basis for delivery of antibody-bound toxin into cells accompanied by its immediate dissociation as the complex enters acidic vesicles...
  81. ncbi request reprint Fruit and vegetable intake and risk of cardiovascular disease: the Women's Health Study
    S Liu
    Division of Preventive Medicine and Channing Laboratory, The Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 72:922-8. 2000
    ..Prospective data relating fruit and vegetable intake to cardiovascular disease (CVD) risk are sparse, particularly for women...
  82. ncbi request reprint Intake of vegetables rich in carotenoids and risk of coronary heart disease in men: The Physicians' Health Study
    S Liu
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Int J Epidemiol 30:130-5. 2001
    ..However, due to the chemical and physical complexity of vegetables, the effects of individual nutrients may differ if eaten as whole foods. Moreover, little is known about the direct association between vegetable intake and risk of CHD...
  83. ncbi request reprint Physical activity and risk for cardiovascular events in diabetic women
    F B Hu
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Ann Intern Med 134:96-105. 2001
    ..Increased physical activity has been associated with reduced risk for cardiovascular disease in the general population, but data are limited on its role among persons with type 2 diabetes mellitus...
  84. ncbi request reprint Diagnostic performance of antineutrophil cytoplasmic antibody tests for idiopathic vasculitides: metaanalysis with a focus on antimyeloperoxidase antibodies
    H K Choi
    Department of Medicine, Massachusetts General Hospital, Boston 02114, USA
    J Rheumatol 28:1584-90. 2001
    ..To summarize the pertinent data, we conducted a metaanalysis examining the diagnostic value of ANCA testing systems that include assays for anti-MPO...
  85. ncbi request reprint Whole grain consumption and risk of ischemic stroke in women: A prospective study
    S Liu
    Division of Preventive Medicine, Bringham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
    JAMA 284:1534-40. 2000
    ..Although increased intake of grain products has been recommended to prevent cardiovascular disease (CVD), prospective data examining the relation of whole grain intake to risk of ischemic stroke are sparse, especially among women...
  86. pmc A prospective study of whole-grain intake and risk of type 2 diabetes mellitus in US women
    S Liu
    Brigham and Women s Hospital, Harvard Medical School, Boston, USA
    Am J Public Health 90:1409-15. 2000
    ..This study examined the association between intake of whole vs refined grain and the risk of type 2 diabetes mellitus...
  87. ncbi request reprint Alcohol consumption and risk of coronary heart disease by diabetes status
    U A Ajani
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215 1204, USA
    Circulation 102:500-5. 2000
    ..To assess whether a similar association exists among diabetics, we examined the relation between light to moderate alcohol consumption and CHD in men with and without diabetes mellitus in a prospective cohort study...
  88. ncbi request reprint A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women
    S Liu
    Departments of Epidemiology and Nutrition, The Harvard School of Public Health, Boston, MA 02215, USA
    Am J Clin Nutr 71:1455-61. 2000
    ..Little is known about the effects of the amount and type of carbohydrates on risk of coronary heart disease (CHD)...
  89. ncbi request reprint Long-term beta-carotene supplementation and risk of type 2 diabetes mellitus: a randomized controlled trial
    S Liu
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    JAMA 282:1073-5. 1999
    ..Recent data suggest a protective role of carotenoids in the development of type 2 diabetes mellitus (DM), possibly via an antioxidant effect, but no randomized trial has directly assessed the efficacy of beta-carotene to prevent DM...
  90. ncbi request reprint Whole-grain consumption and risk of coronary heart disease: results from the Nurses' Health Study
    S Liu
    Division of Preventive Medicine and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 70:412-9. 1999
    ..Although current dietary guidelines for Americans recommend increased intake of grain products to prevent coronary heart disease (CHD), epidemiologic data relating whole-grain intake to the risk of CHD are sparse...
  91. ncbi request reprint Dietary glycemic load assessed by food-frequency questionnaire in relation to plasma high-density-lipoprotein cholesterol and fasting plasma triacylglycerols in postmenopausal women
    S Liu
    Division of Preventive Medicine and the Channing Laboratory, The Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Am J Clin Nutr 73:560-6. 2001
    ..In epidemiologic studies, dietary glycemic load (GL) is positively associated with risk of coronary artery disease and type 2 diabetes...
  92. pmc HbA1c measured in stored erythrocytes and mortality rate among middle-aged and older women
    E B Levitan
    Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, 375 Longwood Avenue, MS 443, Boston, MA 02215, USA
    Diabetologia 51:267-75. 2008
    ..We examined the association between HbA1c measured in stored erythrocytes and mortality rate in women with and without diabetes...
  93. ncbi request reprint Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials
    Y Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Diabet Med 23:1050-6. 2006
    ..The aim of this study was to assess the evidence on the effect of oral magnesium supplementation on glycaemic control in patients with Type 2 diabetes...
  94. ncbi request reprint Prospective study of adult onset diabetes mellitus (type 2) and risk of colorectal cancer in women
    F B Hu
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Natl Cancer Inst 91:542-7. 1999
    ..We prospectively examined the relationship between diabetes and risk of colorectal cancer in a cohort of 118403 women aged 30 through 55 years who were without previously diagnosed cancer at baseline in 1976...
  95. ncbi request reprint Diet, lifestyle, and the risk of type 2 diabetes mellitus in women
    F B Hu
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 345:790-7. 2001
    ..Previous studies have examined individual dietary and lifestyle factors in relation to type 2 diabetes, but the combined effects of these factors are largely unknown...
  96. ncbi request reprint Diet and risk of Type II diabetes: the role of types of fat and carbohydrate
    F B Hu
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetologia 44:805-17. 2001
    ..Dietary recommendations to prevent Type II diabetes should focus more on the quality of fat and carbohydrate in the diet than quantity alone, in addition to balancing total energy intake with expenditure to avoid overweight and obesity...
  97. ncbi request reprint The impact of diabetes mellitus on mortality from all causes and coronary heart disease in women: 20 years of follow-up
    F B Hu
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Arch Intern Med 161:1717-23. 2001
    ..Few data are available on the long-term impact of type 2 diabetes mellitus on total mortality and fatal coronary heart disease (CHD) in women...
  98. ncbi request reprint Plasma sex steroid hormones and risk of developing type 2 diabetes in women: a prospective study
    E L Ding
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Diabetologia 50:2076-84. 2007
    ..We aimed to examine comprehensively plasma sex hormones in connection with risk of developing type 2 diabetes in postmenopausal women...
  99. ncbi request reprint Time urgency and risk of non-fatal myocardial infarction
    S R Cole
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA02215, USA
    Int J Epidemiol 30:363-9. 2001
    ....
  100. pmc Evaluation of a novel food composition database that includes glutamine and other amino acids derived from gene sequencing data
    C M Lenders
    Harvard School of Public Health, Boston, MA, USA
    Eur J Clin Nutr 63:1433-9. 2009
    ..To determine the content of glutamine in major food proteins...
  101. ncbi request reprint Intragastric acid control in non-steroidal anti-inflammatory drug users: comparison of esomeprazole, lansoprazole and pantoprazole
    J L Goldstein
    Department of Medicine, Section of Digestive Diseases and Nutrition, University of Illinois at Chicago, IL 60612, USA
    Aliment Pharmacol Ther 23:1189-96. 2006
    ..Studies to date have not directly compared the pharmacodynamic efficacies of different proton pump inhibitors in controlling intragastric acidity in patients treated with non-steroidal anti-inflammatory drugs...