Sara Lindstrom

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Genetic variation in the upstream region of ERG and prostate cancer
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden
    Cancer Causes Control 20:1173-80. 2009
  2. doi request reprint Y chromosome haplotypes and prostate cancer in Sweden
    Sara Lindstrom
    Department of Medical Epidemiology and Biostatistics and Oncologic Center, Karolinska Institutet, Stockholm, Sweden
    Clin Cancer Res 14:6712-6. 2008
  3. pmc The impact of gene-environment dependence and misclassification in genetic association studies incorporating gene-environment interactions
    Sara Lindstrom
    Department of Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    Hum Hered 68:171-81. 2009
  4. pmc Replication of five prostate cancer loci identified in an Asian population--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3)
    Sara Lindstrom
    Department of Epidemiology, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 21:212-6. 2012
  5. pmc Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies
    Sara Lindstrom
    Department of Epidemiology, Harvard School of Public Health, Building 2, Room 249B, 655 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:873-6. 2010
  6. ncbi request reprint Inherited variation in hormone-regulating genes and prostate cancer survival
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden
    Clin Cancer Res 13:5156-61. 2007
  7. ncbi request reprint Systematic replication study of reported genetic associations in prostate cancer: Strong support for genetic variation in the androgen pathway
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, University of Umea, Umea, Sweden
    Prostate 66:1729-43. 2006
  8. pmc Common genetic variants in prostate cancer risk prediction--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3)
    Sara Lindstrom
    Program in Molecular and Genetic Epidemiology, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 21:437-44. 2012
  9. pmc A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Sara Lindstrom
    Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    J Clin Endocrinol Metab 95:E121-7. 2010
  10. ncbi request reprint Comprehensive genetic evaluation of common E-cadherin sequence variants and prostate cancer risk: strong confirmation of functional promoter SNP
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, University of Umea, 901 87, Umea, Sweden
    Hum Genet 118:339-47. 2005

Detail Information

Publications27

  1. pmc Genetic variation in the upstream region of ERG and prostate cancer
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden
    Cancer Causes Control 20:1173-80. 2009
    ..Here, we investigated if inherited genetic variation upstream of ERG alters prostate cancer risk and survival...
  2. doi request reprint Y chromosome haplotypes and prostate cancer in Sweden
    Sara Lindstrom
    Department of Medical Epidemiology and Biostatistics and Oncologic Center, Karolinska Institutet, Stockholm, Sweden
    Clin Cancer Res 14:6712-6. 2008
    ..Certain Y-chromosomal lineages have been suggested to predispose individuals to prostate cancer in the Japanese population; in other ethnic groups, however, the importance of the Y chromosome is poorly understood...
  3. pmc The impact of gene-environment dependence and misclassification in genetic association studies incorporating gene-environment interactions
    Sara Lindstrom
    Department of Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    Hum Hered 68:171-81. 2009
    ....
  4. pmc Replication of five prostate cancer loci identified in an Asian population--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3)
    Sara Lindstrom
    Department of Epidemiology, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 21:212-6. 2012
    ..In this study, we attempt to replicate these five loci in a series of nested prostate cancer case-control studies of European ancestry...
  5. pmc Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies
    Sara Lindstrom
    Department of Epidemiology, Harvard School of Public Health, Building 2, Room 249B, 655 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:873-6. 2010
    ..Genetic variation in two members of the Toll-like receptor family, TLR4 and the gene cluster TLR6-1-10, has been implicated in prostate cancer in several studies but the associated alleles have not been consistent across reports...
  6. ncbi request reprint Inherited variation in hormone-regulating genes and prostate cancer survival
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden
    Clin Cancer Res 13:5156-61. 2007
    ..However, little is known about genetic determinants of disease progression and prostate cancer-specific death...
  7. ncbi request reprint Systematic replication study of reported genetic associations in prostate cancer: Strong support for genetic variation in the androgen pathway
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, University of Umea, Umea, Sweden
    Prostate 66:1729-43. 2006
    ..Despite considerable efforts and initial promising findings, the field of prostate cancer genetics is characterized by inconclusive reports and no prostate cancer gene has yet been established...
  8. pmc Common genetic variants in prostate cancer risk prediction--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3)
    Sara Lindstrom
    Program in Molecular and Genetic Epidemiology, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 21:437-44. 2012
    ..In this study, we evaluated the discriminative and predictive ability for prostate cancer risk models incorporating 25 common prostate cancer genetic markers, family history of prostate cancer, and age...
  9. pmc A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Sara Lindstrom
    Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    J Clin Endocrinol Metab 95:E121-7. 2010
    ..A long-standing hypothesis has been that inherited variation in the androgen receptor (AR) gene plays a role in prostate cancer initiation. However, studies to date have been inconclusive and often suffered from small sample sizes...
  10. ncbi request reprint Comprehensive genetic evaluation of common E-cadherin sequence variants and prostate cancer risk: strong confirmation of functional promoter SNP
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, University of Umea, 901 87, Umea, Sweden
    Hum Genet 118:339-47. 2005
    ..Due to the difficulties in replication of genetic association studies, this finding is unusual and novel...
  11. pmc Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3
    Sara Lindstrom
    Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 6:e17142. 2011
    ..While these SNPs represent new independent risk factors for prostate cancer, we saw little evidence for effect modification by other SNPs or by the environmental factors examined...
  12. pmc Vitamin D-related genetic variation, plasma vitamin D, and risk of lethal prostate cancer: a prospective nested case-control study
    Irene M Shui
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02215, USA
    J Natl Cancer Inst 104:690-9. 2012
    ..The association of vitamin D status with prostate cancer is controversial; no association has been observed for overall incidence, but there is a potential link with lethal disease...
  13. doi request reprint The UGT2B17 gene deletion is not associated with prostate cancer risk
    Mats Olsson
    Department of Urology, Karolinska University Hospital, Stockholm, Sweden
    Prostate 68:571-5. 2008
    ..Here we determine the risk in a large-scale population-based case-control study...
  14. ncbi request reprint Estrogen receptor beta polymorphism is associated with prostate cancer risk
    Camilla Thellenberg-Karlsson
    Department of Radiation Sciences Oncology, University of Umea, Umea, Sweden
    Clin Cancer Res 12:1936-41. 2006
    ..ERbeta is thought to exert an antiproliferative and proapoptotic effect. We examined whether sequence variants in the ERbeta gene are associated with prostate cancer risk...
  15. ncbi request reprint Germ-line genetic variation in the key androgen-regulating genes androgen receptor, cytochrome P450, and steroid-5-alpha-reductase type 2 is important for prostate cancer development
    Sara Lindstrom
    Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden
    Cancer Res 66:11077-83. 2006
    ..Carriers of five high-risk alleles in the AR, CYP17, and SRD5A2 genes are at approximately 2-fold excess risk to develop prostate cancer...
  16. doi request reprint Influence of MUC1 genetic variation on prostate cancer risk and survival
    Rona J Strawbridge
    Department of Oncology Pathology, Karolinska Institutet Karolinska University Hospital, Stockholm, Sweden
    Eur J Hum Genet 16:1521-5. 2008
    ..Moreover, we observed no association with MUC1 variation and prostate cancer-specific survival. Common variants in MUC1 and the surrounding region are not associated with risk or prognosis of prostate cancer in Swedish men...
  17. pmc Prostate cancer (PCa) risk variants and risk of fatal PCa in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Irene M Shui
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA Electronic address
    Eur Urol 65:1069-75. 2014
    ..Studies have identified multiple genetic risk loci for PCa incidence, but it is unknown whether they could be used as biomarkers for PCa-specific mortality (PCSM)...
  18. pmc A nonparametric test to detect quantitative trait loci where the phenotypic distribution differs by genotypes
    Hugues Aschard
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Genet Epidemiol 37:323-33. 2013
    ..We demonstrate the potential utility of our method on real data by analyzing mammographic density genome-wide data from the Nurses' Health Study...
  19. pmc Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium
    Mitchell J Machiela
    Program in Molecular and Genetic Epidemiology, Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 176:1121-9. 2012
    ..These data suggest a shared genetic component between T2D and PCa and add to the evidence for an interrelation between these diseases...
  20. pmc Genetic variation in the toll-like receptor 4 and prostate cancer incidence and mortality
    Irene M Shui
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Prostate 72:209-16. 2012
    ..Common genetic variants in the Toll-like receptor 4 (TLR4), which is involved in inflammation and immune response pathways, may be important for prostate cancer...
  21. pmc Common variants in ZNF365 are associated with both mammographic density and breast cancer risk
    Sara Lindstrom
    Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Nat Genet 43:185-7. 2011
    ..6 × 10(-10)). Common variants in ZNF365 have also recently been associated with susceptibility to breast cancer...
  22. ncbi request reprint Genetic variation in p53 and ATM haplotypes and risk of glioma and meningioma
    Beatrice Susanne Malmer
    Department of Radiation Sciences, Oncology, Umea University Hospital, 901 85, Umea, Sweden
    J Neurooncol 82:229-37. 2007
    ..Therefore, we tested the hypothesis that polymorphisms and haplotypes in p53 and ATM could be associated with glioma and meningioma risk...
  23. pmc Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study
    Anja Rudolph
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Im Neuenheimer Feld 581, D 69120 Heidelberg, Germany PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA Foundation for Quality and Efficiency in Health Care IQWIG, Cologne, Germany Human Genetics, Genome Institute of Singapore, Singapore, Singapore Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK INSERM National Institute of Health and Medical Research, CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France Unité Mixte de Recherche Scientifique UMRS 1018, University Paris Sud, Villejuif, France Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr Universität Bochum IPA, Bochum, Germany Institute for Occupational Medicine and Maritime Medicine, University Medical Center, Hamburg Eppendorf, Hamburg, Germany Department of Internal Medicine, Telos Pharmaceuticals LLC
    Endocr Relat Cancer 20:875-87. 2013
    ..These findings warrant replication in independent studies...
  24. pmc Plasma carotenoid- and retinol-weighted multi-SNP scores and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Sara J Hendrickson
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 22:927-36. 2013
    ..We determined associations between variants in BCMO1 and breast cancer risk in a large cohort consortium...
  25. pmc Informed conditioning on clinical covariates increases power in case-control association studies
    Noah Zaitlen
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Genet 8:e1003032. 2012
    ..This suggests that applying our method to existing and future association studies of these diseases may identify novel disease loci...
  26. pmc Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer
    Jingmei Li
    Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden
    Breast Cancer Res 12:R19. 2010
    ..In this study, we evaluate the association between mammographic density and genetic variants of the estrogen metabolic pathway...
  27. doi request reprint Cognitive function and other risk factors for mild traumatic brain injury in young men: nationwide cohort study
    Anna Nordström
    Department of Community Medicine and Rehabilitation, Rehabilitation Medicine, Umea University, SE 901 87 Umea, Sweden
    BMJ 346:f723. 2013
    ..To investigate cognitive function and other risk factors for mild traumatic brain injury in young men...