Lingling Li

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc On weighting approaches for missing data
    Lingling Li
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Stat Methods Med Res 22:14-30. 2013
  2. ncbi request reprint A conditional maximized sequential probability ratio test for pharmacovigilance
    Lingling Li
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 133 Brookline Ave, 6th Floor, Boston, MA 02215, USA
    Stat Med 29:284-95. 2010
  3. pmc Propensity score-based sensitivity analysis method for uncontrolled confounding
    Lingling Li
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts 02215, USA
    Am J Epidemiol 174:345-53. 2011
  4. pmc Effect of vitamin D and inhaled corticosteroid treatment on lung function in children
    Ann Chen Wu
    Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA 02215 5301, USA
    Am J Respir Crit Care Med 186:508-13. 2012
  5. ncbi request reprint Multivariable confounding adjustment in distributed data networks without sharing of patient-level data
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 22:1171-7. 2013
  6. doi request reprint Risk of adverse events following oseltamivir treatment in influenza outpatients, Vaccine Safety Datalink Project, 2007-2010
    Sharon K Greene
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts 02215 3920, USA
    Pharmacoepidemiol Drug Saf 22:335-44. 2013
  7. ncbi request reprint Risk of confirmed Guillain-Barre syndrome following receipt of monovalent inactivated influenza A (H1N1) and seasonal influenza vaccines in the Vaccine Safety Datalink Project, 2009-2010
    Sharon K Greene
    Department of Population Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Am J Epidemiol 175:1100-9. 2012
  8. ncbi request reprint Absence of associations between influenza vaccines and increased risks of seizures, Guillain-Barré syndrome, encephalitis, or anaphylaxis in the 2012-2013 season
    Alison Tse Kawai
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 23:548-53. 2014
  9. pmc Near real-time adverse drug reaction surveillance within population-based health networks: methodology considerations for data accrual
    Taliser R Avery
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 22:488-95. 2013
  10. ncbi request reprint A conditional sequential sampling procedure for drug safety surveillance
    Lingling Li
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Ave, 6th Floor, Boston, MA 02215, U S A
    Stat Med 28:3124-38. 2009

Detail Information

Publications22

  1. pmc On weighting approaches for missing data
    Lingling Li
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Stat Methods Med Res 22:14-30. 2013
    ..We then generalise to more complex settings. Our goal is to provide a conceptual overview of existing IPW approaches and illustrate the connections and differences among these approaches...
  2. ncbi request reprint A conditional maximized sequential probability ratio test for pharmacovigilance
    Lingling Li
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 133 Brookline Ave, 6th Floor, Boston, MA 02215, USA
    Stat Med 29:284-95. 2010
    ..Our test incorporates the randomness and variability from both the historical data and the surveillance population. Evaluations of the statistical power for CMaxSPRT are presented under different scenarios...
  3. pmc Propensity score-based sensitivity analysis method for uncontrolled confounding
    Lingling Li
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts 02215, USA
    Am J Epidemiol 174:345-53. 2011
    ....
  4. pmc Effect of vitamin D and inhaled corticosteroid treatment on lung function in children
    Ann Chen Wu
    Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA 02215 5301, USA
    Am J Respir Crit Care Med 186:508-13. 2012
    ..Low vitamin D levels are associated with asthma and decreased airway responsiveness. Treatment with inhaled corticosteroids improves airway responsiveness and asthma control...
  5. ncbi request reprint Multivariable confounding adjustment in distributed data networks without sharing of patient-level data
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 22:1171-7. 2013
    ..We describe and compare two approaches that do not require sharing of patient-level information to adjust for confounding in multi-site studies...
  6. doi request reprint Risk of adverse events following oseltamivir treatment in influenza outpatients, Vaccine Safety Datalink Project, 2007-2010
    Sharon K Greene
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts 02215 3920, USA
    Pharmacoepidemiol Drug Saf 22:335-44. 2013
    ..We assessed oseltamivir safety before and during the pandemic using biologically plausible risk intervals, particularly focusing on psychiatric events...
  7. ncbi request reprint Risk of confirmed Guillain-Barre syndrome following receipt of monovalent inactivated influenza A (H1N1) and seasonal influenza vaccines in the Vaccine Safety Datalink Project, 2009-2010
    Sharon K Greene
    Department of Population Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Am J Epidemiol 175:1100-9. 2012
    ..1 cases per million doses, 95% confidence interval: -3.1, 5.4). Further evaluation to assess GBS risk following both vaccination and respiratory infection is warranted...
  8. ncbi request reprint Absence of associations between influenza vaccines and increased risks of seizures, Guillain-Barré syndrome, encephalitis, or anaphylaxis in the 2012-2013 season
    Alison Tse Kawai
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 23:548-53. 2014
    ..We conducted weekly surveillance for pre-specified adverse events following receipt of the 2012-2013 influenza vaccines in the Vaccine Safety Datalink (VSD)...
  9. pmc Near real-time adverse drug reaction surveillance within population-based health networks: methodology considerations for data accrual
    Taliser R Avery
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 22:488-95. 2013
    ..This study describes practical considerations for implementation of near real-time medical product safety surveillance in a distributed health data network...
  10. ncbi request reprint A conditional sequential sampling procedure for drug safety surveillance
    Lingling Li
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Ave, 6th Floor, Boston, MA 02215, U S A
    Stat Med 28:3124-38. 2009
    ..We end with discussions...
  11. ncbi request reprint A comparison of goodness of fit tests for the logistic GEE model
    Scott Evans
    Department of Biostatistics, Center for Biostatistics in AIDS Research, Harvard School of Public Health, 651 Huntington Avenue, Boston, MA 02115, USA
    Stat Med 24:1245-61. 2005
    ..We evaluate the performance of each of the statistics with respect to type I error rates and power in a simulation study. Guidance is provided regarding appropriate use of the statistics under various scenarios...
  12. pmc Outcomes after periodic use of inhaled corticosteroids in children
    Ann Chen Wu
    Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Medical School, 133 Brookline Avenue, 6th Floor, Boston, MA 02215, USA
    J Asthma 46:517-22. 2009
    ..However, scant information exists on the clinical outcomes of children with asthma who are using inhaled corticosteroids on a periodic basis in real-world settings...
  13. pmc Predictors of symptoms are different from predictors of severe exacerbations from asthma in children
    Ann Chen Wu
    Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA 02215 5301, USA
    Chest 140:100-7. 2011
    ..The goal of our study was (1) to assess the association of asthma symptoms with severe asthma exacerbations and (2) to compare predictors of persistent asthma symptoms and predictors of severe asthma exacerbations...
  14. ncbi request reprint Rapid increase in breast magnetic resonance imaging use: trends from 2000 to 2011
    Natasha K Stout
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts
    JAMA Intern Med 174:114-21. 2014
    ..Low specificity, cost, and little evidence regarding mortality benefits, however, limit recommendations for its use to high-risk women. How breast MRI is actually used in community settings is unknown...
  15. doi request reprint H1N1 and seasonal influenza vaccine safety in the vaccine safety datalink project
    Grace M Lee
    Center for Child Health Care Studies, Department of Population Medicine, Children s Hospital Boston, Boston, Massachusetts, USA
    Am J Prev Med 41:121-8. 2011
    ..A robust influenza immunization program in the U.S. requires ongoing monitoring of potential adverse events associated with vaccination...
  16. ncbi request reprint Risk factors for ventilator-associated events: a case-control multivariable analysis*
    Sarah C Lewis
    1Division of Infectious Disease, University of California San Francisco, San Francisco, CA 2Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 3Department of Medicine, Brigham and Women s Hospital, Boston, MA
    Crit Care Med 42:1839-48. 2014
    ..We sought to identify risk factors for ventilator-associated conditions and infection-related ventilator-associated complications...
  17. ncbi request reprint Orphan therapies: making best use of postmarket data
    Judith C Maro
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 133 Brookline Avenue, 6th Floor, Boston, MA, 02215, USA
    J Gen Intern Med 29:745-51. 2014
    ..Such a network could support sequential statistical analyses designed to detect early warnings of excess risks. We use a simulated example to explore the circumstances under which a distributed network may prove advantageous...
  18. ncbi request reprint The utility of claims data for infection surveillance following anterior cruciate ligament reconstruction
    Michael V Murphy
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts
    Infect Control Hosp Epidemiol 35:652-9. 2014
    ..To explore the feasibility of identifying anterior cruciate ligament (ACL) allograft implantations and infections using claims...
  19. doi request reprint Comparative risk for angioedema associated with the use of drugs that target the renin-angiotensin-aldosterone system
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School, Boston, MA 02215, USA
    Arch Intern Med 172:1582-9. 2012
    ..We assessed the risk for angioedema associated with the use of angiotensin converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), and the direct renin inhibitor aliskiren...
  20. pmc Comparative safety of infliximab and etanercept on the risk of serious infections: does the association vary by patient characteristics?
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Pharmacoepidemiol Drug Saf 21:524-34. 2012
    ..It is unclear whether the risk varies by patient characteristics. We conducted a study to address this question...
  21. pmc Development of a Pharmacogenetic Predictive Test in asthma: proof of concept
    Ann Chen Wu
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 133 Brookline Avenue, 6th Floor, Boston, MA 02215 5301, USA
    Pharmacogenet Genomics 20:86-93. 2010
    ..To assess the feasibility of developing a Combined Clinical and Pharmacogenetic Predictive Test, comprised of multiple single nucleotide polymorphisms (SNPs) that is associated with poor bronchodilator response (BDR)...
  22. pmc Repeatability of response to asthma medications
    Ann Chen Wu
    Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, Mass, USA
    J Allergy Clin Immunol 123:385-90. 2009
    ..Pharmacogenetic studies of drug response in asthma assume that patients respond consistently to a treatment but that treatment response varies across patients; however, no formal studies have demonstrated this...