Research Topics
| James J LevittSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
A volumetric MRI study of limbic, associative and sensorimotor striatal subregions in schizophreniaJames J Levitt
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Brockton Division, Brockton, MA 02301, USA
Schizophr Res 145:11-9. 2013..We thus rigorously parcellated it into subregions in order to assess whether neuroleptic effect on group differences is regionally specific...- Fractional anisotropy and radial diffusivity: diffusion measures of white matter abnormalities in the anterior limb of the internal capsule in schizophreniaJames J Levitt
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Brockton Division, Brockton, MA 02301, United States
Schizophr Res 136:55-62. 2012..We evaluated abnormalities in the ALIC fiber tract in schizophrenia using both structural MRI and diffusion tensor imaging (DTI)... 
Shape abnormalities of caudate nucleus in schizotypal personality disorderJames J Levitt
Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA, USA
Schizophr Res 110:127-39. 2009..Here, we use a new shape measure which importantly permits local in addition to global shape analysis, as well as local correlations with behavioral measures...- A diffusion tensor imaging study of the anterior limb of the internal capsule in schizophreniaJames J Levitt
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Brockton Division, Brockton, MA 02301 and Harvard Medical School, Boston, MA 02115, United States
Psychiatry Res 184:143-50. 2010..Despite not demonstrating a group difference in FA, we found that AL-IC FA was a good predictor of spatial and verbal declarative/episodic memory performance in schizophrenia... 
A selective review of volumetric and morphometric imaging in schizophreniaJames J Levitt
Department of Psychiatry, VA Boston Healthcare System, Harvard Medical School, Brockton Campus, 116A4, 940 Belmont Street, Brockton, MA 02301, USA
Curr Top Behav Neurosci 4:243-81. 2010..Additional studies assessing morphometry at different phases of the illness, including prodromal stages, together with longitudinal studies will elucidate further the role of progression in this disorder...- Shape of caudate nucleus and its cognitive correlates in neuroleptic-naive schizotypal personality disorderJames J Levitt
Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton, Massachusetts 02301, USA
Biol Psychiatry 55:177-84. 2004.... - Olfactory sulcal depth and olfactory bulb volume in patients with schizophrenia: an MRI studyAn D Nguyen
Department of Psychiatry at the VA Boston Healthcare System, Harvard Medical School, Brockton, MA, USA
Brain Imaging Behav 5:252-61. 2011..Overall, our findings support earlier research studies showing morphometric and functional changes in the olfactory system in patients with schizophrenia... - Thalamo-frontal white matter alterations in chronic schizophrenia: a quantitative diffusion tractography studyJungsu S Oh
Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Hum Brain Mapp 30:3812-25. 2009..These findings suggest that our method can enhance the regional and functional specificity of DTI group studies, thus improving our understanding of brain function... - An in vivo MRI study of prefrontal cortical complexity in first-episode psychosisLaura C Wiegand
Clinical Neuroscience Division, Laboratory of Neuroscience, VA Boston Healthcare System-Brockton Division, Harvard Medical School, Brockton, MA 02301, USA
Am J Psychiatry 162:65-70. 2005..CONCLUSIONS: An abnormal pattern of asymmetry in the prefrontal cortex of first-episode patients with schizophrenia provides evidence for a neurodevelopmental mechanism in the etiology of schizophrenia... - Smaller neocortical gray matter and larger sulcal cerebrospinal fluid volumes in neuroleptic-naive women with schizotypal personality disorderMin-Seong Koo
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA 02301, USA
Arch Gen Psychiatry 63:1090-100. 2006..CONCLUSIONS: The smaller neocortical gray matter volume and larger sulcal CSF volume provide evidence of the brain basis of this personality disorder and emphasize the communality of brain abnormalities in the schizophrenia spectrum... - Reduction of caudate nucleus volumes in neuroleptic-naïve female subjects with schizotypal personality disorderMin-Seong Koo
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, and Harvard Medical School, Boston, MA 02401, USA
Biol Psychiatry 60:40-8. 2006..CONCLUSIONS: These findings demonstrate that, for female SPD subjects, smaller caudate volume is associated with poorer cognitive performance and more schizotypal symptomatology... - MRI study of caudate nucleus volume and its cognitive correlates in neuroleptic-naive patients with schizotypal personality disorderJames J Levitt
Clinical Neuroscience Division, Laboratory of Neuroscience, Dept. of Psychiatry, VA Boston Healthcare System-Brockton Division, Harvard Medical School, 940 Belmont Street, Brockton, MA 02301, USA
Am J Psychiatry 159:1190-7. 2002.... - Prefrontal cortical thickness in first-episode psychosis: a magnetic resonance imaging studyLaura C Wiegand
Department of Psychiatry, Harvard Medical School, Brockton, Massachusetts 02301, USA
Biol Psychiatry 55:131-40. 2004.... - Orbitofrontal volume deficit in schizophrenia and thought disorderMotoaki Nakamura
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, MA 02301, USA
Brain 131:180-95. 2008..In HC the finding of a quantitative association between OFC volume and IGT performance constitutes, to our knowledge, the first report of this association... - Characterizing the shape of anatomical structures with Poisson's equationHaissam Haidar
Department of Neurology, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA
IEEE Trans Med Imaging 25:1249-57. 2006..In the second study, we present a data set of caudate nuclei of premature infants with asymmetric white matter injury. Our method shows structural shape differences that volumetric measurements were unable to detect... - Fornix integrity and hippocampal volume in male schizophrenic patientsNoriomi Kuroki
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Boston VA Healthcare System, Brockton Division, and Harvard Medical School, Brockton, Massachusetts, USA
Biol Psychiatry 60:22-31. 2006..CONCLUSIONS: These findings demonstrate a disruption in fornix integrity in patients with schizophrenia... - Anterior limb of the internal capsule in schizophrenia: a diffusion tensor tractography studyGudrun Rosenberger
Psychiatry Neuroimaging Laboratory, Department of Psychiatry and Radiology, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street, Boston, MA 02215, USA
Brain Imaging Behav 6:417-25. 2012.... - An MRI study of septi pellucidi in relation to hippocampus volume and fornix integrity in schizophreniaCharlie A Davidson
Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston St, Boston, MA 02215, United States
Schizophr Res 134:165-70. 2012..SP were larger in chronic SZ, but not in FESZ. In chronic SZ only, SP-Length was correlated negatively with fornix-FA and hippocampal volume, and positively with chlorpromazine-equivalent dosage... - A cross-sectional and longitudinal magnetic resonance imaging study of cingulate gyrus gray matter volume abnormalities in first-episode schizophrenia and first-episode affective psychosisMin Seong Koo
Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA 02301, USA
Arch Gen Psychiatry 65:746-60. 2008..However, it is unclear whether these gray matter abnormalities show a subregional specificity to either disorder and whether they show postonset progression... - Altered orbitofrontal sulcogyral pattern in schizophreniaMotoaki Nakamura
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, MA, USA
Brain 130:693-707. 2007.... - MCMC curve sampling for image segmentationAyres C Fan
Laboratory for Information and Decision Systems, MIT, Cambridge, MA, USA
Med Image Comput Comput Assist Interv 10:477-85. 2007.... - Neuropsychological variability, symptoms, and brain imaging in chronic schizophreniaPaul G Nestor
Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
Brain Imaging Behav 7:68-76. 2013.... - The relationship between reward-based learning and nicotine dependence in smokers with schizophreniaChristopher G AhnAllen
VA Boston Healthcare System, Brockton, MA 02301 5596, USA
Psychiatry Res 196:9-14. 2012..These findings emphasize the importance of targeting reward system functioning in smoking cessation treatment for individuals with schizophrenia... - In search of the functional neuroanatomy of sociality: MRI subdivisions of orbital frontal cortex and social cognitionPaul G Nestor
Department of Psychology, University of Massachusetts, Boston, USA
Soc Cogn Affect Neurosci 8:460-7. 2013..To our knowledge, these findings are the first to show evidence linking normal variation in OFC subregions and different aspects of social cognition... - Olfactory dysfunction in schizophrenia: a review of neuroanatomy and psychophysiological measurementsAn D Nguyen
Harvard Medical School, MA, USA
Harv Rev Psychiatry 18:279-92. 2010..The possible role of these changes as biological markers of the disorder will be discussed, as will potentially productive directions for future research... - White matter tract abnormalities between rostral middle frontal gyrus, inferior frontal gyrus and striatum in first-episode schizophreniaMeina Quan
Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02301, USA
Schizophr Res 145:1-10. 2013..This study examines white matter integrity of the tracts connecting DLPFC/VLPFC and striatum in patients with first-episode schizophrenia (FESZ), and their associations with cognitive and clinical correlates... - A unifying approach to registration, segmentation, and intensity correctionKilian M Pohl
Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, Cambridge, MA, USA
Med Image Comput Comput Assist Interv 8:310-8. 2005..We demonstrate the approach on a set of 22 magnetic resonance images. In addition, we show that the approach performs better than similar methods which separate the registration and segmentation problems... - Volume of cerebellar vermis in monozygotic twins discordant for combat exposure: lack of relationship to post-traumatic stress disorderJames J Levitt
VA Boston Healthcare System, Clinical Neuroscience Division, Laboratory of Neuroscience, Brockton, MA 02301, USA
Psychiatry Res 148:143-9. 2006..Thus, the results do not support the structural abnormality of cerebellar vermis in combat-related PTSD...