James J Levitt

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint A volumetric MRI study of limbic, associative and sensorimotor striatal subregions in schizophrenia
    James J Levitt
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Brockton Division, Brockton, MA 02301, USA
    Schizophr Res 145:11-9. 2013
  2. doi request reprint Fractional anisotropy and radial diffusivity: diffusion measures of white matter abnormalities in the anterior limb of the internal capsule in schizophrenia
    James J Levitt
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Brockton Division, Brockton, MA 02301, United States
    Schizophr Res 136:55-62. 2012
  3. pmc Shape abnormalities of caudate nucleus in schizotypal personality disorder
    James J Levitt
    Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA, USA
    Schizophr Res 110:127-39. 2009
  4. doi request reprint A diffusion tensor imaging study of the anterior limb of the internal capsule in schizophrenia
    James J Levitt
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Brockton Division, Brockton, MA 02301 and Harvard Medical School, Boston, MA 02115, United States
    Psychiatry Res 184:143-50. 2010
  5. ncbi request reprint A selective review of volumetric and morphometric imaging in schizophrenia
    James J Levitt
    Department of Psychiatry, VA Boston Healthcare System, Harvard Medical School, Brockton Campus, 116A4, 940 Belmont Street, Brockton, MA 02301, USA
    Curr Top Behav Neurosci 4:243-81. 2010
  6. pmc Shape of caudate nucleus and its cognitive correlates in neuroleptic-naive schizotypal personality disorder
    James J Levitt
    Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton, Massachusetts 02301, USA
    Biol Psychiatry 55:177-84. 2004
  7. doi request reprint Olfactory sulcal depth and olfactory bulb volume in patients with schizophrenia: an MRI study
    An D Nguyen
    Department of Psychiatry at the VA Boston Healthcare System, Harvard Medical School, Brockton, MA, USA
    Brain Imaging Behav 5:252-61. 2011
  8. pmc Thalamo-frontal white matter alterations in chronic schizophrenia: a quantitative diffusion tractography study
    Jungsu S Oh
    Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Hum Brain Mapp 30:3812-25. 2009
  9. doi request reprint Neuropsychological variability, symptoms, and brain imaging in chronic schizophrenia
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    Brain Imaging Behav 7:68-76. 2013
  10. pmc An in vivo MRI study of prefrontal cortical complexity in first-episode psychosis
    Laura C Wiegand
    Clinical Neuroscience Division, Laboratory of Neuroscience, VA Boston Healthcare System Brockton Division, Harvard Medical School, Brockton, MA 02301, USA
    Am J Psychiatry 162:65-70. 2005

Collaborators

Detail Information

Publications29

  1. doi request reprint A volumetric MRI study of limbic, associative and sensorimotor striatal subregions in schizophrenia
    James J Levitt
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Brockton Division, Brockton, MA 02301, USA
    Schizophr Res 145:11-9. 2013
    ..We thus rigorously parcellated it into subregions in order to assess whether neuroleptic effect on group differences is regionally specific...
  2. doi request reprint Fractional anisotropy and radial diffusivity: diffusion measures of white matter abnormalities in the anterior limb of the internal capsule in schizophrenia
    James J Levitt
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Brockton Division, Brockton, MA 02301, United States
    Schizophr Res 136:55-62. 2012
    ..We evaluated abnormalities in the ALIC fiber tract in schizophrenia using both structural MRI and diffusion tensor imaging (DTI)...
  3. pmc Shape abnormalities of caudate nucleus in schizotypal personality disorder
    James J Levitt
    Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA, USA
    Schizophr Res 110:127-39. 2009
    ..Here, we use a new shape measure which importantly permits local in addition to global shape analysis, as well as local correlations with behavioral measures...
  4. doi request reprint A diffusion tensor imaging study of the anterior limb of the internal capsule in schizophrenia
    James J Levitt
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, Brockton Division, Brockton, MA 02301 and Harvard Medical School, Boston, MA 02115, United States
    Psychiatry Res 184:143-50. 2010
    ..Despite not demonstrating a group difference in FA, we found that AL-IC FA was a good predictor of spatial and verbal declarative/episodic memory performance in schizophrenia...
  5. ncbi request reprint A selective review of volumetric and morphometric imaging in schizophrenia
    James J Levitt
    Department of Psychiatry, VA Boston Healthcare System, Harvard Medical School, Brockton Campus, 116A4, 940 Belmont Street, Brockton, MA 02301, USA
    Curr Top Behav Neurosci 4:243-81. 2010
    ..Additional studies assessing morphometry at different phases of the illness, including prodromal stages, together with longitudinal studies will elucidate further the role of progression in this disorder...
  6. pmc Shape of caudate nucleus and its cognitive correlates in neuroleptic-naive schizotypal personality disorder
    James J Levitt
    Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton, Massachusetts 02301, USA
    Biol Psychiatry 55:177-84. 2004
    ..We believe MRI shape analysis complements traditional MRI volume measurements...
  7. doi request reprint Olfactory sulcal depth and olfactory bulb volume in patients with schizophrenia: an MRI study
    An D Nguyen
    Department of Psychiatry at the VA Boston Healthcare System, Harvard Medical School, Brockton, MA, USA
    Brain Imaging Behav 5:252-61. 2011
    ..Overall, our findings support earlier research studies showing morphometric and functional changes in the olfactory system in patients with schizophrenia...
  8. pmc Thalamo-frontal white matter alterations in chronic schizophrenia: a quantitative diffusion tractography study
    Jungsu S Oh
    Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Hum Brain Mapp 30:3812-25. 2009
    ..These findings suggest that our method can enhance the regional and functional specificity of DTI group studies, thus improving our understanding of brain function...
  9. doi request reprint Neuropsychological variability, symptoms, and brain imaging in chronic schizophrenia
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA 02125 3393, USA
    Brain Imaging Behav 7:68-76. 2013
    ....
  10. pmc An in vivo MRI study of prefrontal cortical complexity in first-episode psychosis
    Laura C Wiegand
    Clinical Neuroscience Division, Laboratory of Neuroscience, VA Boston Healthcare System Brockton Division, Harvard Medical School, Brockton, MA 02301, USA
    Am J Psychiatry 162:65-70. 2005
    ..The purpose of this study was to investigate abnormalities in the surface complexity of the prefrontal cortex and in the hemispheric asymmetry of cortical complexity in first-episode patients with schizophrenia...
  11. pmc Reduction of caudate nucleus volumes in neuroleptic-naïve female subjects with schizotypal personality disorder
    Min Seong Koo
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, and Harvard Medical School, Boston, MA 02401, USA
    Biol Psychiatry 60:40-8. 2006
    ....
  12. ncbi request reprint Smaller neocortical gray matter and larger sulcal cerebrospinal fluid volumes in neuroleptic-naive women with schizotypal personality disorder
    Min Seong Koo
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA 02301, USA
    Arch Gen Psychiatry 63:1090-100. 2006
    ..Structural brain abnormalities, including larger cerebrospinal fluid (CSF) volumes, have been observed in men diagnosed as having schizotypal personality disorder (SPD)...
  13. doi request reprint White matter tract abnormalities between rostral middle frontal gyrus, inferior frontal gyrus and striatum in first-episode schizophrenia
    Meina Quan
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02301, USA
    Schizophr Res 145:1-10. 2013
    ..This study examines white matter integrity of the tracts connecting DLPFC/VLPFC and striatum in patients with first-episode schizophrenia (FESZ), and their associations with cognitive and clinical correlates...
  14. pmc MRI study of caudate nucleus volume and its cognitive correlates in neuroleptic-naive patients with schizotypal personality disorder
    James J Levitt
    Clinical Neuroscience Division, Laboratory of Neuroscience, Dept of Psychiatry, VA Boston Healthcare System Brockton Division, Harvard Medical School, 940 Belmont Street, Brockton, MA 02301, USA
    Am J Psychiatry 159:1190-7. 2002
    ....
  15. pmc Prefrontal cortical thickness in first-episode psychosis: a magnetic resonance imaging study
    Laura C Wiegand
    Department of Psychiatry, Harvard Medical School, Brockton, Massachusetts 02301, USA
    Biol Psychiatry 55:131-40. 2004
    ..Findings from postmortem studies suggest reduced prefrontal cortical thickness in schizophrenia; however, cortical thickness in first-episode schizophrenia has not been evaluated using magnetic resonance imaging (MRI)...
  16. pmc Orbitofrontal volume deficit in schizophrenia and thought disorder
    Motoaki Nakamura
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, MA 02301, USA
    Brain 131:180-95. 2008
    ..In HC the finding of a quantitative association between OFC volume and IGT performance constitutes, to our knowledge, the first report of this association...
  17. pmc Characterizing the shape of anatomical structures with Poisson's equation
    Haissam Haidar
    Department of Neurology, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    IEEE Trans Med Imaging 25:1249-57. 2006
    ..In the second study, we present a data set of caudate nuclei of premature infants with asymmetric white matter injury. Our method shows structural shape differences that volumetric measurements were unable to detect...
  18. pmc In search of the functional neuroanatomy of sociality: MRI subdivisions of orbital frontal cortex and social cognition
    Paul G Nestor
    Department of Psychology, University of Massachusetts, Boston, MA, USA
    Soc Cogn Affect Neurosci 8:460-7. 2013
    ..To our knowledge, these findings are the first to show evidence linking normal variation in OFC subregions and different aspects of social cognition...
  19. doi request reprint An MRI study of septi pellucidi in relation to hippocampus volume and fornix integrity in schizophrenia
    Charlie A Davidson
    Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston St, Boston, MA 02215, United States
    Schizophr Res 134:165-70. 2012
    ..SP were larger in chronic SZ, but not in FESZ. In chronic SZ only, SP-Length was correlated negatively with fornix-FA and hippocampal volume, and positively with chlorpromazine-equivalent dosage...
  20. pmc Altered orbitofrontal sulcogyral pattern in schizophrenia
    Motoaki Nakamura
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Brockton, MA, USA
    Brain 130:693-707. 2007
    ....
  21. pmc Fornix integrity and hippocampal volume in male schizophrenic patients
    Noriomi Kuroki
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Boston VA Healthcare System, Brockton Division, and Harvard Medical School, Brockton, Massachusetts, USA
    Biol Psychiatry 60:22-31. 2006
    ..Few studies have evaluated the fornix in schizophrenia, however. A focus on fornix abnormalities and their association with hippocampal abnormalities might figure importantly in our understanding of the pathophysiology of schizophrenia...
  22. doi request reprint Anterior limb of the internal capsule in schizophrenia: a diffusion tensor tractography study
    Gudrun Rosenberger
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry and Radiology, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street, Boston, MA 02215, USA
    Brain Imaging Behav 6:417-25. 2012
    ....
  23. ncbi request reprint MCMC curve sampling for image segmentation
    Ayres C Fan
    Laboratory for Information and Decision Systems, MIT, Cambridge, MA, USA
    Med Image Comput Comput Assist Interv 10:477-85. 2007
    ....
  24. pmc A cross-sectional and longitudinal magnetic resonance imaging study of cingulate gyrus gray matter volume abnormalities in first-episode schizophrenia and first-episode affective psychosis
    Min Seong Koo
    Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA 02301, USA
    Arch Gen Psychiatry 65:746-60. 2008
    ..However, it is unclear whether these gray matter abnormalities show a subregional specificity to either disorder and whether they show postonset progression...
  25. pmc The relationship between reward-based learning and nicotine dependence in smokers with schizophrenia
    Christopher G AhnAllen
    VA Boston Healthcare System, Brockton, MA 02301 5596, USA
    Psychiatry Res 196:9-14. 2012
    ..These findings emphasize the importance of targeting reward system functioning in smoking cessation treatment for individuals with schizophrenia...
  26. doi request reprint Prefrontal cortex volume deficit in schizophrenia: A new look using 3T MRI with manual parcellation
    Toshiyuki Ohtani
    Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, VA, Boston Healthcare System, Brockton Division, and Harvard Medical School, Boston, MA 02301, USA Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA Safety and Health Organization, Chiba University, Chiba City 263 8522, Japan Electronic address
    Schizophr Res 152:184-90. 2014
    ..440, p=0.025). In summary, 3-T imaging revealed widespread gyral volume deficits in PFC gyri, and specific associations with selective negative symptoms, such as affective flattening, and with deficits in cognitive switching. ..
  27. doi request reprint Olfactory dysfunction in schizophrenia: a review of neuroanatomy and psychophysiological measurements
    An D Nguyen
    Harvard Medical School, MA, USA
    Harv Rev Psychiatry 18:279-92. 2010
    ..The possible role of these changes as biological markers of the disorder will be discussed, as will potentially productive directions for future research...
  28. pmc A unifying approach to registration, segmentation, and intensity correction
    Kilian M Pohl
    Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, Cambridge, MA, USA
    Med Image Comput Comput Assist Interv 8:310-8. 2005
    ..We demonstrate the approach on a set of 22 magnetic resonance images. In addition, we show that the approach performs better than similar methods which separate the registration and segmentation problems...
  29. pmc Volume of cerebellar vermis in monozygotic twins discordant for combat exposure: lack of relationship to post-traumatic stress disorder
    James J Levitt
    VA Boston Healthcare System, Clinical Neuroscience Division, Laboratory of Neuroscience, Brockton, MA 02301, USA
    Psychiatry Res 148:143-9. 2006
    ..Thus, the results do not support the structural abnormality of cerebellar vermis in combat-related PTSD...