Alan Leviton

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Clinical practice guidelines and practice parameters for the child neurologist
    Alan Leviton
    Department of Neurology, Boston Children s Hospital and Harvard Medical School, Boston, MA, USA
    J Child Neurol 28:917-25. 2013
  2. pmc Two-hit model of brain damage in the very preterm newborn: small for gestational age and postnatal systemic inflammation
    Alan Leviton
    Department of Neurology, Boston Children s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Pediatr Res 73:362-70. 2013
  3. pmc Systemic responses of preterm newborns with presumed or documented bacteraemia
    Alan Leviton
    Department of Neurology, Children s Hospital Boston, and Harvard Medical School, Boston, MA 02215 5349, USA
    Acta Paediatr 101:355-9. 2012
  4. doi request reprint What is quality improvement and why should child neurologists care?
    Alan Leviton
    Departments of Neurology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    J Child Neurol 27:251-7. 2012
  5. pmc Relationships among the concentrations of 25 inflammation-associated proteins during the first postnatal weeks in the blood of infants born before the 28th week of gestation
    Alan Leviton
    Department of Neurology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115 5724, USA
    Cytokine 57:182-90. 2012
  6. ncbi request reprint The adaptive immune response in neonatal cerebral white matter damage
    Alan Leviton
    Neuroepidemiology Unit, Children s Hospital Boston, 1 Autumn Street, Boston, MA 02215 5349, USA
    Ann Neurol 58:821-8. 2005
  7. pmc Early blood gas abnormalities and the preterm brain
    Alan Leviton
    Neuroepidemiology Unit, Neurology Department, Children s Hospital Boston, and Harvard Medical School, Boston, Massachusetts 02215 5724, USA
    Am J Epidemiol 172:907-16. 2010
  8. doi request reprint Blood protein concentrations in the first two postnatal weeks associated with early postnatal blood gas derangements among infants born before the 28th week of gestation. The ELGAN Study
    Alan Leviton
    Department of Neurology, Children s Hospital Boston, and Harvard Medical School, Boston, MA 02115, USA
    Cytokine 56:392-8. 2011
  9. doi request reprint Persistence after birth of systemic inflammation associated with umbilical cord inflammation
    Alan Leviton
    Department of Neurology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Reprod Immunol 90:235-43. 2011
  10. ncbi request reprint Intraventricular haemorrhage grading scheme: time to abandon?
    Alan Leviton
    Department of Neurology, Children s Hospital, Harvard Medical School, Boston, MA, USA
    Acta Paediatr 96:1254-6. 2007

Detail Information

Publications82

  1. doi request reprint Clinical practice guidelines and practice parameters for the child neurologist
    Alan Leviton
    Department of Neurology, Boston Children s Hospital and Harvard Medical School, Boston, MA, USA
    J Child Neurol 28:917-25. 2013
    ..and adhered to, what influences acceptance and adherence, do guidelines improve care, do they reduce costs, will they be viewed by courts as the standard of care, how can they be updated and improved, and are there better alternatives?..
  2. pmc Two-hit model of brain damage in the very preterm newborn: small for gestational age and postnatal systemic inflammation
    Alan Leviton
    Department of Neurology, Boston Children s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Pediatr Res 73:362-70. 2013
    ..We sought to disentangle the contributions of perinatal systemic inflammation and being small for gestational age (SGA) to the occurrence of low Bayley Mental Development Indices (MDIs) at the age of 2 y...
  3. pmc Systemic responses of preterm newborns with presumed or documented bacteraemia
    Alan Leviton
    Department of Neurology, Children s Hospital Boston, and Harvard Medical School, Boston, MA 02215 5349, USA
    Acta Paediatr 101:355-9. 2012
    ....
  4. doi request reprint What is quality improvement and why should child neurologists care?
    Alan Leviton
    Departments of Neurology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    J Child Neurol 27:251-7. 2012
    ....
  5. pmc Relationships among the concentrations of 25 inflammation-associated proteins during the first postnatal weeks in the blood of infants born before the 28th week of gestation
    Alan Leviton
    Department of Neurology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115 5724, USA
    Cytokine 57:182-90. 2012
    ..Inflammation appears to be involved in processes leading to organ damage in preterm newborns, yet little is known about the relationships among elevated concentrations of inflammation-associated proteins in the blood of preterm newborns...
  6. ncbi request reprint The adaptive immune response in neonatal cerebral white matter damage
    Alan Leviton
    Neuroepidemiology Unit, Children s Hospital Boston, 1 Autumn Street, Boston, MA 02215 5349, USA
    Ann Neurol 58:821-8. 2005
    ..These include specific recognition of bacterial antigens, specific recognition of autoantigens, polyclonal activation by Toll-like receptors, and bystander activation by cytokines...
  7. pmc Early blood gas abnormalities and the preterm brain
    Alan Leviton
    Neuroepidemiology Unit, Neurology Department, Children s Hospital Boston, and Harvard Medical School, Boston, Massachusetts 02215 5724, USA
    Am J Epidemiol 172:907-16. 2010
    ..Findings suggest that individual blood gas derangements do not increase brain damage risk. Rather, the multiple derangements associated with indicators of brain damage might be indicators of immaturity/vulnerability and illness severity...
  8. doi request reprint Blood protein concentrations in the first two postnatal weeks associated with early postnatal blood gas derangements among infants born before the 28th week of gestation. The ELGAN Study
    Alan Leviton
    Department of Neurology, Children s Hospital Boston, and Harvard Medical School, Boston, MA 02115, USA
    Cytokine 56:392-8. 2011
    ..To explore the relationships between blood gas derangements and blood concentrations of inflammation-related proteins shortly after preterm birth...
  9. doi request reprint Persistence after birth of systemic inflammation associated with umbilical cord inflammation
    Alan Leviton
    Department of Neurology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Reprod Immunol 90:235-43. 2011
    ....
  10. ncbi request reprint Intraventricular haemorrhage grading scheme: time to abandon?
    Alan Leviton
    Department of Neurology, Children s Hospital, Harvard Medical School, Boston, MA, USA
    Acta Paediatr 96:1254-6. 2007
  11. ncbi request reprint Neuronal damage accompanies perinatal white-matter damage
    Alan Leviton
    Department of Neurology, Children s Hospital Boston, Boston, MA, USA
    Trends Neurosci 30:473-8. 2007
    ..Together, these advances support the untested hypothesis that white-matter damage in the preterm newborn is accompanied by the death of neurons as they migrate through the dangerous minefield of white matter undergoing injury...
  12. doi request reprint Early postnatal blood concentrations of inflammation-related proteins and microcephaly two years later in infants born before the 28th post-menstrual week
    Alan Leviton
    Children s Hospital Boston, Boston MA 02115 5724, United States
    Early Hum Dev 87:325-30. 2011
    ..To evaluate if concentrations of inflammation-related proteins were elevated in early postnatal blood specimens of preterm newborns who two years later had a small head...
  13. pmc Antenatal antecedents of a small head circumference at age 24-months post-term equivalent in a sample of infants born before the 28th post-menstrual week
    Alan Leviton
    Department of Neurology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    Early Hum Dev 86:515-21. 2010
    ..Little is known about the antecedents of microcephaly in early childhood among children born at extremely low gestational age...
  14. pmc Inflammation-related proteins in the blood of extremely low gestational age newborns. The contribution of inflammation to the appearance of developmental regulation
    Alan Leviton
    Neurology Department, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    Cytokine 53:66-73. 2011
    ..We wanted to assess to what extent concentrations of circulating proteins appear to be developmentally regulated, and to what extent such regulation is influenced by intra-uterine inflammation...
  15. doi request reprint The relationship between early concentrations of 25 blood proteins and cerebral white matter injury in preterm newborns: the ELGAN study
    Alan Leviton
    Neuroepidemiology Unit, Department of Neurology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    J Pediatr 158:897-903.e1-5. 2011
    ..To evaluate whether concentrations of inflammation-related proteins are elevated in the blood of preterm newborns who develop cerebral white matter damage...
  16. doi request reprint The clustering of disorders in infants born before the 28th week of gestation
    Alan Leviton
    Neurology Department, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
    Acta Paediatr 99:1795-800. 2010
    ..To see whether disorders prevalent in infants born extremely preterm cluster...
  17. pmc SNAP-II and SNAPPE-II and the risk of structural and functional brain disorders in extremely low gestational age newborns: the ELGAN study
    Olaf Dammann
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Mass 02111, USA
    Neonatology 97:71-82. 2010
    ..Illness severity measures predict death and illnesses in the newborn. It is unknown how well they predict brain lesions evident on ultrasound scans or neurodevelopmental dysfunctions in preterm infants...
  18. pmc Developmental correlates of head circumference at birth and two years in a cohort of extremely low gestational age newborns
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, MA, USA
    J Pediatr 155:344-9.e1-3. 2009
    ..To evaluate the developmental correlates of microcephaly evident at birth and at 2 years in a cohort born at extremely low gestational age...
  19. pmc Factors associated with small head circumference at birth among infants born before the 28th week
    Thomas F McElrath
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 203:138.e1-8. 2010
    ..We sought to identify risk factors for congenital microcephaly in extremely low gestational age newborns...
  20. pmc Maternal antenatal complications and the risk of neonatal cerebral white matter damage and later cerebral palsy in children born at an extremely low gestational age
    Thomas F McElrath
    Division of Maternal Fetal Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Epidemiol 170:819-28. 2009
    ....
  21. doi request reprint The Modified Checklist for Autism in Toddlers in extremely low gestational age newborns: individual items associated with motor, cognitive, vision and hearing limitations
    RHIANNON J LUYSTER
    Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Harvard Medical School, Boston, MA 02215, USA
    Paediatr Perinat Epidemiol 25:366-76. 2011
    ..The strong association between impaired sensory or motor function and M-CHAT results among extremely low gestational age children suggests that such impairments might give rise to false positive M-CHAT screening...
  22. pmc Colonization of second-trimester placenta parenchyma
    Andrew B Onderdonk
    Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 199:52.e1-52.e10. 2008
    ..The overtly healthy, nonpregnant uterus harbors bacteria, Mycoplasma and Ureaplasma. The extent of colonization remains elusive, as are relationships between isolated microorganisms, preterm labor and fetal inflammation...
  23. ncbi request reprint Systemic inflammation, intraventricular hemorrhage, and white matter injury
    Alan Leviton
    1Department of Neurology, Children s Hospital, Boston, MA, USA
    J Child Neurol 28:1637-45. 2013
    ..Each entity is associated with inflammation, but the combination has a stronger inflammatory signal than hemorrhage alone. ..
  24. ncbi request reprint Is maternal obesity associated with sustained inflammation in extremely low gestational age newborns?
    Jelske W van der Burg
    Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, United States Department of Health Sciences and the EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands
    Early Hum Dev 89:949-55. 2013
    ..The offspring of obese women are at increased risk for systemic inflammation. Blood concentrations of inflammatory proteins in preterm newborns of obese women have not been reported...
  25. doi request reprint Characterization of chorioamnionitis in 2nd-trimester C-section placentas and correlation with microorganism recovery from subamniotic tissues
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Pediatr Dev Pathol 11:15-22. 2008
    ..Recovery of microorganisms from placental parenchyma is associated with histologic inflammation. The same microorganisms responsible for inciting high-grade chorionic plate inflammation are also most likely to promote fetal inflammation...
  26. pmc Relationship Between Neonatal Blood Protein Concentrations and Placenta Histologic Characteristics in Extremely Low GA Newborns
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Pediatr Res 69:68-73. 2011
    ..These results confirm the predictive value of placental histology for the presence or absence of elevated inflammatory response in newborns...
  27. pmc Cranial ultrasound lesions in the NICU predict cerebral palsy at age 2 years in children born at extremely low gestational age
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, Massachusetts, USA
    J Child Neurol 24:63-72. 2009
    ..Nearly half the cerebral palsy identified at 2 years is not preceded by a neonatal brain ultrasound abnormality...
  28. pmc Histological characteristics of singleton placentas delivered before the 28th week of gestation
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02118, USA
    Pathology 40:372-6. 2008
    ..We describe the histological characteristics of 947 singleton placentas from infants born between 23 and 27 weeks gestation...
  29. pmc Fetal-placental inflammation, but not adrenal activation, is associated with extreme preterm delivery
    Sunita Trivedi
    Division of Endocrinology, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Am J Obstet Gynecol 206:236.e1-8. 2012
    ..Our objective was to determine whether placental corticotropin-releasing hormone is activated in extreme preterm labor...
  30. doi request reprint Does bronchopulmonary dysplasia contribute to the occurrence of cerebral palsy among infants born before 28 weeks of gestation?
    Linda J Van Marter
    Newborn Medicine, Children s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
    Arch Dis Child Fetal Neonatal Ed 96:F20-9. 2011
    ..To evaluate the relationships among cerebral palsy (CP) phenotypes and bronchopulmonary dysplasia (BPD) severity and, in the process, to generate hypotheses regarding causal pathways linking BPD to CP...
  31. pmc Cluster analysis of placental inflammatory proteins can distinguish preeclampsia from preterm labor and premature membrane rupture in singleton deliveries less than 28 weeks of gestation
    Jessica M Faupel-Badger
    Cancer Prevention Fellowship Program, National Cancer Institute, Bethesda, MD 20892 7105, USA
    Am J Reprod Immunol 66:488-94. 2011
    ..The risks of complications are different between iatrogenic (e.g. PE) and spontaneous (e.g. PL and membrane rupture) causes of preterm delivery, suggesting different underlying biology contributes to these placental conditions...
  32. doi request reprint Neonatal bacteremia and retinopathy of prematurity: the ELGAN study
    Kristi Washburn Tolsma
    Division of Newborn Medicine, Floating Hospital for Children, Tufts Medical Center, 800 Washington St, PO Box 854, Boston, MA 02111 1526, USA
    Arch Ophthalmol 129:1555-63. 2011
    ..To explore whether early or late and presumed or definite neonatal bacteremia are associated with an increased risk of severe retinopathy of prematurity (ROP)...
  33. pmc Microbiologic and histologic characteristics of the extremely preterm infant's placenta predict white matter damage and later cerebral palsy. the ELGAN study
    Alan Leviton
    Department of Neurology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    Pediatr Res 67:95-101. 2010
    ..Organism recovery does not seem to be needed for placenta inflammation to predict diparetic CP...
  34. pmc Maternal microbe-specific modulation of inflammatory response in extremely low-gestational-age newborns
    Raina N Fichorova
    Laboratory of Genital Tract Biology, Department of Obstetrics and Gynecology, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
    MBio 2:e00280-10. 2011
    ..This study provides evidence that microorganisms colonizing the placenta provoke distinctive newborn inflammatory responses and that Lactobacillus may suppress these responses...
  35. doi request reprint Early cranial ultrasound lesions predict microcephaly at age 2 years in preterm infants
    Kalpathy S Krishnamoorthy
    Department of Neurology Pediatrics, Massachusetts General Hospital, Boston, Massachusetts, Harvard Medical School, Harvard University, Boston, Massachusetts, USA
    J Child Neurol 26:188-94. 2011
    ..Focal white-matter lesion (echolucent lesion) and diffuse white-matter damage (ventriculomegaly) predict an increased risk of microcephaly...
  36. pmc Presumed and definite bacteremia in extremely low gestational age newborns
    Sonal Patel
    Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111, USA
    Acta Paediatr 100:36-41. 2011
    ..To explore risk patterns for presumed and definite, early and late neonatal bacteremia...
  37. ncbi request reprint Prolonged latency after preterm premature rupture of membranes: an evaluation of histologic condition and intracranial ultrasonic abnormality in the neonate born at <28 weeks of gestation
    Thomas F McElrath
    Division of Maternal Fetal Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 189:794-8. 2003
    ....
  38. pmc Positive screening on the Modified Checklist for Autism in Toddlers (M-CHAT) in extremely low gestational age newborns
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, MA 02118, USA
    J Pediatr 154:535-540.e1. 2009
    ..To test the hypothesis that children born preterm are more likely to screen positive on the M-CHAT for an autism spectrum disorder...
  39. doi request reprint Systemic inflammation associated with severe intestinal injury in extremely low gestational age newborns
    Camilia R Martin
    Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Fetal Pediatr Pathol 32:222-34. 2013
    ..A better understanding of systemic inflammation might help prevent and treat these disorders...
  40. pmc Birth weight- and fetal weight-growth restriction: impact on neurodevelopment
    Iris G Streimish
    Newborn Medicine, Newton Wellesley Hospital, Newton, MA, USA
    Early Hum Dev 88:765-71. 2012
    ..The newborn classified as growth-restricted on fetal weight curves, but not on birth weight curves, is classified prenatally as small for gestational age (SGA), but postnatally as appropriate for gestational age (AGA)...
  41. pmc Neurodevelopment of extremely preterm infants who had necrotizing enterocolitis with or without late bacteremia
    Camilia R Martin
    Department of Neonatology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, USA
    J Pediatr 157:751-6.e1. 2010
    ..To evaluate neurodevelopment after necrotizing enterocolitis (NEC) and late bacteremia, alone and together...
  42. ncbi request reprint Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infants
    Linda J Van Marter
    Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Pediatr 140:171-6. 2002
    ..This case-control study of chronic lung disease (CLD) evaluated the hypothesis that chorioamnionitis promotes CLD and interacts with other risk factors for CLD, including mechanical ventilation and postnatal infection...
  43. pmc Interinstitutional variation in prediction of death by SNAP-II and SNAPPE-II among extremely preterm infants
    Olaf Dammann
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Massachusetts 02111, USA
    Pediatrics 124:e1001-6. 2009
    ..Illness severity scores predict death among infants admitted to NICUs. We know of no study limited to a population defined by an extremely low gestational age...
  44. ncbi request reprint Antenatal glucocorticoids increase early total thyroxine levels in premature infants
    Camilia R Martin
    Department of Neonatology, Beth Israel Deaconess Medical Center, Division of Newborn Medicine, Boston, MA 02215, USA
    Biol Neonate 87:273-80. 2005
    ..It is standard obstetrical practice to offer antenatal glucocorticoids to pregnant women with threatened preterm delivery. Few studies have investigated the effect of antenatal glucocorticoids on neonatal thyroid function...
  45. pmc Placenta microbiology and histology and the risk for severe retinopathy of prematurity
    Minghua L Chen
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Massachusetts 02111 1526, USA
    Invest Ophthalmol Vis Sci 52:7052-8. 2011
    ..To test the hypothesis that the presence of bacteria and/or histologic inflammation in the placenta of infants born preterm is associated with an increased risk for severe retinopathy of prematurity (ROP)...
  46. doi request reprint Pregnancy disorders appear to modify the risk for retinopathy of prematurity associated with neonatal hyperoxemia and bacteremia
    Jennifer W Lee
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111, USA
    J Matern Fetal Neonatal Med 26:811-8. 2013
    ....
  47. pmc Perturbation of gene expression of the chromatin remodeling pathway in premature newborns at risk for bronchopulmonary dysplasia
    Jennifer Cohen
    Children s Hospital, Boston, Division of Newborn Medicine, Boston, Longwood Avenue, Boston, MA 02115, USA
    Genome Biol 8:R210. 2007
    ..Sections of umbilical cord were obtained at birth from 20 infants who later developed BPD and from 34 of their peers who did not develop BPD...
  48. ncbi request reprint Risk of cranial ultrasound abnormalities in very-low-birth-weight infants conceived with assisted reproductive techniques
    Jane E Stewart
    Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    J Perinatol 22:37-45. 2002
    ....
  49. pmc Reader variability in the use of diagnostic terms to describe white matter lesions seen on cranial scans of severely premature infants: the ELGAN study
    Sjirk Westra
    Massachusetts General Hospital, Department of Radiology, Boston, Massachusetts, USA
    J Clin Ultrasound 38:409-19. 2010
    ..To evaluate reader variability of white matter lesions seen on cranial sonographic scans of extreme low gestational age neonates (ELGANs)...
  50. doi request reprint Blood protein profiles of infants born before 28 weeks differ by pregnancy complication
    Thomas F McElrath
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 204:418.e1-418.e12. 2011
    ..Disorders that lead to preterm delivery influence the fetal inflammatory response...
  51. pmc Early nutrition and weight gain in preterm newborns and the risk of retinopathy of prematurity
    Deborah K Vanderveen
    Department of Ophthalmology, Boston Children s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    PLoS ONE 8:e64325. 2013
    ..To identify nutritional and weight gain limitations associated with retinopathy of prematurity (ROP) severity among very preterm newborns...
  52. ncbi request reprint Systemic hypotension and white-matter damage in preterm infants
    Olaf Dammann
    Children s Hospital, Boston, MA 02115, USA
    Dev Med Child Neurol 44:82-90. 2002
    ..In sum, these results do not support the hypothesis that systemic hypotension contributes to echolucency among preterm infants...
  53. doi request reprint Detection of bacteria in placental tissues obtained from extremely low gestational age neonates
    Andrew B Onderdonk
    Harvard Medical School and the Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 198:110.e1-7. 2008
    ..The objective of the study was to quantify and identify aerobic and anaerobic bacteria as well as Mycoplasma and Ureaplasma in the chorionic parenchyma...
  54. pmc An algorithm for identifying and classifying cerebral palsy in young children
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, MA, USA
    J Pediatr 153:466-72. 2008
    ....
  55. ncbi request reprint Retinopathy of prematurity and brain damage in the very preterm newborn
    Elizabeth N Allred
    Boston Children s Hospital and Harvard Medical School, Boston, Massachusetts
    J AAPOS 18:241-7. 2014
    ..To explain why very preterm newborns who develop retinopathy of prematurity (ROP) appear to be at increased risk of abnormalities of both brain structure and function...
  56. doi request reprint Should readmission within 30 days after discharge of children hospitalized for a neurologic disorder be considered a quality assurance failure?
    Elizabeth Allred
    Quality Improvement Team, Department of Neurology, Boston Children s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
    J Child Neurol 28:758-61. 2013
    ..We encourage more study to identify the correlates of readmission of children who have a neurologic disorder...
  57. doi request reprint Risk factors and correlates of neonatal growth velocity in extremely low gestational age newborns. the ELGAN Study
    Julie Bartholomew
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Mass, USA
    Neonatology 104:298-304. 2013
    ..To identify maternal and infant characteristics associated with reduced growth velocity (GV) in extremely premature newborns...
  58. ncbi request reprint Methodologic issues in epidemiologic studies of congenital microcephaly
    Alan Leviton
    Department of Neurology, Harvard Medical School and Children s Hospital, Neuroepidemiology Unit, Boston, MA 02115 5724, USA
    Early Hum Dev 69:91-105. 2002
    ..We pay particular attention to three concerns: Who is a case? How should cases be classified? To whom should cases be compared?..
  59. ncbi request reprint Coagulation, inflammation, and the risk of neonatal white matter damage
    Alan Leviton
    Neuroepidemiology Unit, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Pediatr Res 55:541-5. 2004
    ....
  60. pmc Nutritional practices and growth velocity in the first month of life in extremely premature infants
    Camilia R Martin
    Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Pediatrics 124:649-57. 2009
    ....
  61. pmc Neuregulin-1: a potential endogenous protector in perinatal brain white matter damage
    Olaf Dammann
    Division of Newborn Medicine, Department of Pediatrics, Tufts New England Medical Center, Boston, Mass, USA
    Neonatology 93:182-7. 2008
    ..We outline how NRG-1 might be involved in perinatal brain damage pathomechanisms and suggest that NRG-1 might be one target for intervention...
  62. ncbi request reprint Thymus involution and cerebral white matter damage in extremely low gestational age neonates
    Joshua David Kuban
    Boston University School of Public Health, Boston, Mass, USA
    Biol Neonate 90:252-7. 2006
    ..Among newborns who die, those who have cerebral white matter damage are more likely than others to have thymus involution and low thymus weights...
  63. pmc Observer variability assessing US scans of the preterm brain: the ELGAN study
    Karl Kuban
    Division of Pediatric Neurology, Boston University Medical Center, Boston University School of Medicine, Boston, MA, USA
    Pediatr Radiol 37:1201-8. 2007
    ..Neurosonography can assist clinicians and can provide researchers with documentation of brain lesions. Unfortunately, we know little about the reliability of sonographically derived diagnoses...
  64. ncbi request reprint The wealth of information conveyed by gestational age
    Alan Leviton
    Children s Hospital and Department of Neurology, Harvard Medical School, Boston, MA 02115, USA
    J Pediatr 146:123-7. 2005
  65. ncbi request reprint Perinatal infection, fetal inflammatory response, white matter damage, and cognitive limitations in children born preterm
    Olaf Dammann
    Neuroepidemiology Unit, Department of Neurology, Children s Hospital, Boston, Massachusetts 02115, USA
    Ment Retard Dev Disabil Res Rev 8:46-50. 2002
    ..We conclude that the relationship between antenatal infection and cognitive limitations deserves much further attention by researchers interested in the prevention of this undesirable outcome of prematurity...
  66. pmc Pregnancy disorders that lead to delivery before the 28th week of gestation: an epidemiologic approach to classification
    T F McElrath
    Division of Maternal Fetal Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Am J Epidemiol 168:980-9. 2008
    ..Disorders leading to preterm delivery may be separated into two groups: those associated with intrauterine inflammation and those associated with aberrations of placentation...
  67. ncbi request reprint Why the term neonatal encephalopathy should be preferred over neonatal hypoxic-ischemic encephalopathy
    Alan Leviton
    Department of Neurology, Boston Children s Hospital and Harvard Medical School, Boston, MA, USA
    Am J Obstet Gynecol 208:176-80. 2013
    ..In this clinic opinion piece, I discuss the importance to obstetricians of this decision and explain why "newborn encephalopathy" should be the default term...
  68. ncbi request reprint Lung and brain damage in preterm newborns, and their association with gestational age, prematurity subgroup, infection/inflammation and long term outcome
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Department of Obstetrics and Pediatrics, OE 6415 Hannover Medical School, 30623 Hannover, Germany
    BJOG 112:4-9. 2005
    ..In this paper we discuss the complexities that paediatricians, perinatologists and perinatal epidemiologists face as they try to understand the contributions of factors associated with preterm birth to neonatal and childhood disorders...
  69. ncbi request reprint Antenatal mycoplasma infection, the fetal inflammatory response and cerebral white matter damage in very-low-birthweight infants
    Olaf Dammann
    Hannover Medical School, Germany
    Paediatr Perinat Epidemiol 17:49-57. 2003
    ..Our finding that M. hominis in the placenta was associated with a not quite significant threefold risk increase for echolucency deserves further investigation...
  70. ncbi request reprint Bronchopulmonary dysplasia is not associated with ultrasound-defined cerebral white matter damage in preterm newborns
    Olaf Dammann
    Department of Obstetrics, Prenatal Medicine and Gynecology, Hannover Medical School, 30623 Hannover, Germany
    Pediatr Res 55:319-25. 2004
    ..Confounding does not seem to account for this lack of association between WMD and BPD. In conclusion, our findings do not support the hypothesis that BPD contributes to the occurrence of sonographically defined WMD...
  71. ncbi request reprint Lung and brain damage in preterm newborns. Are they related? How? Why?
    Olaf Dammann
    Departments of Obstetrics and Pediatrics, Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Hannover, Germany
    Biol Neonate 85:305-13. 2004
    ..g. postnatal steroid exposure) that increase the risk for developmental disability in childhood...
  72. ncbi request reprint Periventricular leukomalacia might not specifically affect cortical magnetoencephalographic response to biological motion
    Olaf Dammann
    Ann Neurol 60:269; author reply 269-70. 2006
  73. ncbi request reprint Inflammatory brain damage in preterm newborns--dry numbers, wet lab, and causal inferences
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Germany
    Early Hum Dev 79:1-15. 2004
    ..We also need more (and more detailed) observational studies clarifying the presumed infection --> inflammation --> WMD sequence before we can initiate intervention trials to reduce the risk of WMD...
  74. ncbi request reprint Inflammation, brain damage and visual dysfunction in preterm infants
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Department of Gynecology, Hannover Medical School, OE 6415, 30623 Hannover, Germany
    Semin Fetal Neonatal Med 11:363-8. 2006
    ....
  75. pmc Neonatal cranial ultrasound lesions and developmental delays at 2 years of age among extremely low gestational age children
    T MICHAEL O'SHEA
    Wake Forest University Health Sciences, Department of Pediatrics, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Pediatrics 122:e662-9. 2008
    ..Studies of the relationship between ultrasound images from preterm newborns and developmental delay most often are based on small samples defined by birth weight and exclude infants not testable with standardized assessments...
  76. ncbi request reprint A report: the definition and classification of cerebral palsy April 2006
    Peter Rosenbaum
    CanChild Centre for Childhood Disability Research, Hamilton, Ontario, Canada
    Dev Med Child Neurol Suppl 109:8-14. 2007
    ..The Executive Committee presents this report with the intent of providing a common conceptualization of CP for use by a broad international audience...
  77. ncbi request reprint Neurological sequelae in in-vitro fertilisation babies
    Alan Leviton
    Lancet 360:718; author reply 719. 2002
  78. pmc Factors associated with treatment for hypotension in extremely low gestational age newborns during the first postnatal week
    Matthew Laughon
    School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Pediatrics 119:273-80. 2007
    ....
  79. ncbi request reprint Neuroimaging and the prediction of outcomes in preterm infants
    Olaf Dammann
    N Engl J Med 355:727-9. 2006
  80. ncbi request reprint Video and CD-ROM as a training tool for performing neurologic examinations of 1-year-old children in a multicenter epidemiologic study
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, MA 02118, USA
    J Child Neurol 20:829-31. 2005
    ..It provides an effective means to evaluate interobserver variability, offers a route for feedback, and creates an opportunity to reevaluate variability, both immediately and at periodic intervals...
  81. ncbi request reprint Biomarker epidemiology of cerebral palsy
    Olaf Dammann
    Ann Neurol 55:158-61. 2004
  82. ncbi request reprint Proposed definition and classification of cerebral palsy, April 2005
    Martin Bax
    Division of Paediatrics, Obstetrics and Gynaecology, Imperial College, London, UK
    Dev Med Child Neurol 47:571-6. 2005
    ..The Executive Committee presents this revision and welcomes substantive comments about it...