Sandra J Lee

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Effectiveness of early detection on breast cancer mortality reduction in Catalonia (Spain)
    Montserrat Rue
    Biomedical Research Institut of Lleida IRBLLEIDA, Lleida, Catalonia, Spain
    BMC Cancer 9:326. 2009
  2. ncbi Modelling the early detection of breast cancer
    S J Lee
    Dana Farber Cancer Institute and the Harvard School of Public Health, Boston, MA 02115, USA
    Ann Oncol 14:1199-202. 2003
  3. ncbi Early detection of disease and scheduling of screening examinations
    Sandra Lee
    Dana Faber Cancer Institute, Department of Biostatistics and Computational Biology, 44 Binney Street, Boston, MA 02115, USA
    Stat Methods Med Res 13:443-56. 2004
  4. ncbi Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges
    Samir K Lakhashe
    Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA 02215, USA
    Vaccine 29:5611-22. 2011
  5. ncbi Pre-transplantation physical and mental functioning is strongly associated with self-reported recovery from stem cell transplantation
    D J Andorsky
    Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA
    Bone Marrow Transplant 37:889-95. 2006
  6. ncbi HLA-C mismatch is associated with inferior survival after unrelated donor non-myeloablative hematopoietic stem cell transplantation
    V T Ho
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Bone Marrow Transplant 37:845-50. 2006
  7. ncbi Lower costs associated with hematopoietic cell transplantation using reduced intensity vs high-dose regimens for hematological malignancy
    A M Saito
    Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Bone Marrow Transplant 40:209-17. 2007
  8. ncbi Routine screening for psychosocial distress following hematopoietic stem cell transplantation
    S J Lee
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Bone Marrow Transplant 35:77-83. 2005
  9. ncbi Partial CD8+ T-cell depletion of allogeneic peripheral blood stem cell transplantation is insufficient to prevent graft-versus-host disease
    V T Ho
    Department of Medical Oncology, Biostatistics, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Bone Marrow Transplant 34:987-94. 2004
  10. ncbi The effect of thrombin on ACL fibroblast interactions with collagen hydrogels
    M M Murray
    Department of Orthopaedic Surgery, Children s Hospital of Boston, 300 Longwood Avenue, Boston, Massachusetts 02115, USA
    J Orthop Res 24:508-15. 2006

Research Grants

  1. Breast Cancer: Role of Early Detection, Treatment and Prevention
    Sandra Lee; Fiscal Year: 2007

Collaborators

Detail Information

Publications30

  1. ncbi Effectiveness of early detection on breast cancer mortality reduction in Catalonia (Spain)
    Montserrat Rue
    Biomedical Research Institut of Lleida IRBLLEIDA, Lleida, Catalonia, Spain
    BMC Cancer 9:326. 2009
    ....
  2. ncbi Modelling the early detection of breast cancer
    S J Lee
    Dana Farber Cancer Institute and the Harvard School of Public Health, Boston, MA 02115, USA
    Ann Oncol 14:1199-202. 2003
    ..The theoretical model is general and may be applied to other chronic diseases, which satisfy the basic assumptions...
  3. ncbi Early detection of disease and scheduling of screening examinations
    Sandra Lee
    Dana Faber Cancer Institute, Department of Biostatistics and Computational Biology, 44 Binney Street, Boston, MA 02115, USA
    Stat Methods Med Res 13:443-56. 2004
    ..Examinations are carried out when an individual's risk status reaches a preassigned threshold value.)...
  4. ncbi Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges
    Samir K Lakhashe
    Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA 02215, USA
    Vaccine 29:5611-22. 2011
    ..Thus, vaccine-induced immune responses and relatively lower numbers of potential target cells were associated with protection...
  5. ncbi Pre-transplantation physical and mental functioning is strongly associated with self-reported recovery from stem cell transplantation
    D J Andorsky
    Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA
    Bone Marrow Transplant 37:889-95. 2006
    ..Measurement of baseline QOL can help place the effects of the transplantation procedure in context...
  6. ncbi HLA-C mismatch is associated with inferior survival after unrelated donor non-myeloablative hematopoietic stem cell transplantation
    V T Ho
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Bone Marrow Transplant 37:845-50. 2006
    ..0001). Cumulative relapse incidence was 35% in the HLA-C-mismatched and 55% in the 10/10-matched cohort, P=0.09. HLA-C mismatch is associated with inferior survival after URD NST...
  7. ncbi Lower costs associated with hematopoietic cell transplantation using reduced intensity vs high-dose regimens for hematological malignancy
    A M Saito
    Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Bone Marrow Transplant 40:209-17. 2007
    ..Our data suggest that substantially lower costs and fewer days of hospitalization within the first year after RICT procedures can be obtained with no compromise of long-term clinical outcomes compared to HDCT procedures...
  8. ncbi Routine screening for psychosocial distress following hematopoietic stem cell transplantation
    S J Lee
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Bone Marrow Transplant 35:77-83. 2005
    ..Pre-transplant distress appears to be highly predictive of distress post transplant and is a feasible marker to target screening and intervention programs...
  9. ncbi Partial CD8+ T-cell depletion of allogeneic peripheral blood stem cell transplantation is insufficient to prevent graft-versus-host disease
    V T Ho
    Department of Medical Oncology, Biostatistics, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Bone Marrow Transplant 34:987-94. 2004
    ..There was no correlation between CD8+ number and GVHD or survival. A 2-log depletion of CD8+ cells from PBSC is insufficient to prevent GVHD...
  10. ncbi The effect of thrombin on ACL fibroblast interactions with collagen hydrogels
    M M Murray
    Department of Orthopaedic Surgery, Children s Hospital of Boston, 300 Longwood Avenue, Boston, Massachusetts 02115, USA
    J Orthop Res 24:508-15. 2006
    ..Use of low concentrations of thrombin (10.5 IU/mL) may be beneficial in applications where a faster set time and enhanced cell migration are desirable and the gel mechanical strength is of secondary importance...
  11. ncbi The impact of risk information on patients' willingness to pay for autologous blood donation
    S J Lee
    Division of Hematology Oncology, Brigham and Women s Hospital, Boston, MA, USA
    Med Care 36:1162-73. 1998
    ....
  12. ncbi Early cervical adenocarcinoma: selection criteria for radical surgery
    J O Schorge
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Boston, Massachusetts, 02115, USA
    Obstet Gynecol 94:386-90. 1999
    ..To identify selection criteria for radical surgery in early cervical adenocarcinoma based on pretreatment clinical stage and correlation with high-risk surgical-pathologic factors...
  13. ncbi Predicting costs of stem-cell transplantation
    S J Lee
    Department of Adult Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Clin Oncol 18:64-71. 2000
    ..We sought (1) to determine whether obtaining baseline information enabled identification of patients whose treatments would be the most costly and (2) to estimate inpatient costs for managing specific transplantation complications...
  14. ncbi Outcomes research in oncology: history, conceptual framework, and trends in the literature
    S J Lee
    Center for Outcomes and Policy Research, Department of Adult Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Natl Cancer Inst 92:195-204. 2000
    ..We suggest that as different branches of investigation develop their own literature and methodology-in effect, outgrowing the generic label of outcomes research-they become identified by separate, more precise terms...
  15. ncbi Recovery after stem-cell transplantation for hematologic diseases
    S J Lee
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 19:242-52. 2001
    ....
  16. ncbi Chronic myelogenous leukaemia
    S J Lee
    Center for Outcomes and Policy Research, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Br J Haematol 111:993-1009. 2000
    ..Clinical and laboratory science seems poised to add novel therapies to the armamentarium against CML. It is exciting to contemplate what reviews of CML written 10 years from now will discuss...
  17. ncbi Discrepancies between patient and physician estimates for the success of stem cell transplantation
    S J Lee
    Center for Outcomes and Policy Research, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    JAMA 285:1034-8. 2001
    ..Stem cell transplantation is associated with considerable morbidity and mortality. The extent to which patients and their physicians correctly estimate these risks is unknown...
  18. ncbi Prognostic factors for early severe pulmonary complications after hematopoietic stem cell transplantation
    V T Ho
    Department of Adult Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Biol Blood Marrow Transplant 7:223-9. 2001
    ..Patients with pretransplantation FEV1 of < or = 80% appear to have a higher risk for SPCs...
  19. ncbi A phase I/II double-blind, placebo-controlled study of recombinant human interleukin-11 for mucositis and acute GVHD prevention in allogeneic stem cell transplantation
    J H Antin
    Department of Adult Oncology and Biostatistical Science, Dana-Farber Cancer Institute, Boston, MA 02115, USA
    Bone Marrow Transplant 29:373-7. 2002
    ..The use of IL-11 as GVHD prophylaxis in allogeneic transplantation cannot be recommended as administered in this trial...
  20. ncbi Mortality modeling of early detection programs
    Sandra J Lee
    Harvard School of Public Health and the Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Biometrics 64:386-95. 2008
    ....
  21. ncbi Quality of life associated with acute and chronic graft-versus-host disease
    S J Lee
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    Bone Marrow Transplant 38:305-10. 2006
    ..The adverse effects of acute GVHD are detectable with the TOI at 6 months post transplantation after which development of chronic GVHD is the most strongly correlated with worse QOL...
  22. ncbi Relative transmissibility of an R5 clade C simian-human immunodeficiency virus across different mucosae in macaques parallels the relative risks of sexual HIV-1 transmission in humans via different routes
    Agnes L Chenine
    Dana Farber Cancer Institute, Massachusetts General Hospital, Boston, Massachusetts 02115 6084, USA
    J Infect Dis 201:1155-63. 2010
    ..Worldwide, approximately 90% of all human immunodeficiency virus (HIV) transmissions occur mucosally; almost all involve R5 strains. Risks of sexual HIV acquisition are highest for rectal, then vaginal, and finally oral exposures...
  23. ncbi Durable protection from Herpes Simplex Virus-2 transmission following intravaginal application of siRNAs targeting both a viral and host gene
    Yichao Wu
    The Immune Disease Institute and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
    Cell Host Microbe 5:84-94. 2009
    ..Combining siRNAs targeting a viral and host gene protects mice from HSV-2 for a week, irrespective of the time of challenge. Therefore, intravaginal siRNAs could provide sustained protection against viral transmission...
  24. ncbi Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic
    Dong Zhang
    Center for Blood Research, Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
    Blood 101:226-35. 2003
    ..Impaired antiviral cytotoxicity during chronic infection is not specific to HIV but likely represents the immune response to chronic antigenic exposure...
  25. ncbi Statistical models for screening: planning public health programs
    Sandra J Lee
    Department of Biostatistics, Harvard School of Public Health, Dana-Farber Cancer Institute, USA
    Cancer Treat Res 113:19-36. 2002
  26. ncbi Mitoxantrone, etoposide, and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome: a phase III trial (E2995)
    Peter L Greenberg
    Hematology Division, Stanford University Medical Center, 703 Welch Rd, Suite G 1, Stanford, CA 94305, USA
    J Clin Oncol 22:1078-86. 2004
    ....
  27. ncbi Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials
    Edward L Korn
    Biometric Research Branch, EPN 8129, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA
    J Clin Oncol 26:527-34. 2008
    ....
  28. ncbi Proliferation responses to HIVp24 during antiretroviral therapy do not reflect improved immune phenotype or function
    Christoph G Lange
    Center for AIDS Research, Department of Medicine, Division of Infectious Diseases, Case Western Reserve University, University Hospitals of Cleveland, 2061 Cornell Road, Cleveland, OH 44106, USA
    AIDS 18:605-13. 2004
    ....
  29. ncbi Intensified induction chemotherapy in adult acute myeloid leukemia followed by high-dose chemotherapy and autologous peripheral blood stem cell transplantation: an Eastern Cooperative Oncology Group trial (E4995)
    Peter A Cassileth
    University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA
    Leuk Lymphoma 46:55-61. 2005
    ..Nevertheless, intensive post-remission therapy was well tolerated, no treatment-related mortality occurred with autologous PBSCT, and disease-free survival and overall survival were lengthy...
  30. ncbi Models and the early detection of disease: methodological considerations
    Marvin Zelen
    Department of Biostatistics, Harvard School of Public Health, Dana-Farber Cancer Institute, USA
    Cancer Treat Res 113:1-18. 2002

Research Grants2

  1. Breast Cancer: Role of Early Detection, Treatment and Prevention
    Sandra Lee; Fiscal Year: 2007
    ....