Jonghwan Lee

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Early capillary flux homogenization in response to neural activation
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
    J Cereb Blood Flow Metab 36:375-80. 2016
  2. pmc Quantitative imaging of cerebral blood flow velocity and intracellular motility using dynamic light scattering-optical coherence tomography
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Cereb Blood Flow Metab 33:819-25. 2013
  3. pmc Frequency-domain measurement of neuronal activity using dynamic optical coherence tomography
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Conf Proc IEEE Eng Med Biol Soc 2012:2643-6. 2012
  4. pmc Multiphysics neuron model for cellular volume dynamics
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    IEEE Trans Biomed Eng 58:3000-3. 2011
  5. pmc Motion correction for phase-resolved dynamic optical coherence tomography imaging of rodent cerebral cortex
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, 149 Thirteenth Street, Charlestown, MA 02129, USA
    Opt Express 19:21258-70. 2011
  6. pmc Multiple-capillary measurement of RBC speed, flux, and density with optical coherence tomography
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA
    J Cereb Blood Flow Metab 33:1707-10. 2013
  7. pmc Dynamic light scattering optical coherence tomography
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Opt Express 20:22262-77. 2012
  8. doi request reprint High-resolution in vivo optical imaging of stroke injury and repair
    Sava Sakadzic
    Optics Division, MHG MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA Electronic address
    Brain Res 1623:174-92. 2015

Collaborators

Detail Information

Publications8

  1. doi request reprint Early capillary flux homogenization in response to neural activation
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
    J Cereb Blood Flow Metab 36:375-80. 2016
    ..This network-level data is consistent with the theoretical hypothesis that capillary flow homogenizes during activation to improve oxygen delivery. ..
  2. pmc Quantitative imaging of cerebral blood flow velocity and intracellular motility using dynamic light scattering-optical coherence tomography
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Cereb Blood Flow Metab 33:819-25. 2013
    ..This result supports that the IM measured in this study represent the cellular energy metabolism-related active motion of intracellular organelles rather than free diffusion of intracellular macromolecules...
  3. pmc Frequency-domain measurement of neuronal activity using dynamic optical coherence tomography
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Conf Proc IEEE Eng Med Biol Soc 2012:2643-6. 2012
    ..This spectrum change was only observed during contralateral stimulation and highly localized at the stimulation frequency in the frequency space. Therefore, the spectrum change we observed is likely associated with neuronal activation...
  4. pmc Multiphysics neuron model for cellular volume dynamics
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    IEEE Trans Biomed Eng 58:3000-3. 2011
    ....
  5. pmc Motion correction for phase-resolved dynamic optical coherence tomography imaging of rodent cerebral cortex
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, 149 Thirteenth Street, Charlestown, MA 02129, USA
    Opt Express 19:21258-70. 2011
    ..5 to 0.8 in terms of the cross-correlation over 4 s of dynamic imaging, and reduced phase noise by two orders of magnitude in ~8% voxels...
  6. pmc Multiple-capillary measurement of RBC speed, flux, and density with optical coherence tomography
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA
    J Cereb Blood Flow Metab 33:1707-10. 2013
    ..Further, we demonstrate the ability to quantify RBC speed, flux, and linear density. This technique will provide a means to monitor microvascular flow dynamics over many capillaries at different depths at the same time. ..
  7. pmc Dynamic light scattering optical coherence tomography
    Jonghwan Lee
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Opt Express 20:22262-77. 2012
    ..As an example application, we performed DLS-OCT imaging of the living animal brain, resulting in 3D maps of the absolute and axial velocities, the diffusion coefficient, and the coefficient of determination...
  8. doi request reprint High-resolution in vivo optical imaging of stroke injury and repair
    Sava Sakadzic
    Optics Division, MHG MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA Electronic address
    Brain Res 1623:174-92. 2015
    ..This article is part of a Special Issue entitled SI: Cell Interactions In Stroke. ..