D M Langenau

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish
    D M Langenau
    Stem Cell Program and Division of Hematology Oncology, Children s Hospital Boston and Dana Farber Cancer Institute, Boston, MA 2115, USA
    Oncogene 27:4242-8. 2008
  2. ncbi request reprint Molecular cloning and developmental expression of Tlx (Hox11) genes in zebrafish (Danio rerio)
    D M Langenau
    Department of Pediatric Oncology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Mech Dev 117:243-8. 2002
  3. pmc BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals
    C A Jette
    Department of Pediatric Oncology, Harvard Medical School, Boston, MA 02115, USA
    Cell Death Differ 15:1063-72. 2008
  4. ncbi request reprint Myelopoiesis in the zebrafish, Danio rerio
    C M Bennett
    Department of Pediatric Oncology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Blood 98:643-51. 2001
  5. pmc Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency
    J S Blackburn
    Department of Pathology, Molecular Pathology Unit, Massachusetts General Hospital, Boston, MA, USA
    Leukemia 26:2069-78. 2012
  6. ncbi request reprint Conservation of steroidogenic acute regulatory (StAR) protein structure and expression in vertebrates
    M P Bauer
    Department of Biological Sciences, University of Notre Dame, PO Box 369, Notre Dame IN 46556, USA
    Mol Cell Endocrinol 168:119-25. 2000

Collaborators

  • A T Look
  • N S Trede
  • B H Paw
  • S Liu
  • J S Blackburn
  • C A Jette
  • H Feng
  • A Bernards
  • C M Bennett
  • D M Raiser
  • S Ramaswamy
  • S A Martinez
  • N D Meeker
  • J Gentry
  • D Neuberg
  • M P Bauer
  • A Letai
  • J Ryan
  • R A Stewart
  • A M Flanagan
  • S Carbonneau
  • U J Pyati
  • A Delahaye-Brown
  • M D Fleming
  • J P Kanki
  • J Rhodes
  • L I Zon
  • T X Liu
  • M W Kieran
  • F W Goetz
  • A L Johnson
  • J T Bridgham

Detail Information

Publications6

  1. pmc Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish
    D M Langenau
    Stem Cell Program and Division of Hematology Oncology, Children s Hospital Boston and Dana Farber Cancer Institute, Boston, MA 2115, USA
    Oncogene 27:4242-8. 2008
    ..Using this mosaic transgenic approach, gene pathways involved in tumor initiation and radiation sensitivity have been identified...
  2. ncbi request reprint Molecular cloning and developmental expression of Tlx (Hox11) genes in zebrafish (Danio rerio)
    D M Langenau
    Department of Pediatric Oncology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Mech Dev 117:243-8. 2002
    ..However, only Tlx-3a is expressed in the statoacoustic cranial ganglia, enteric neurons and non-neural tissues such as the fin bud and pharyngeal arches and Tlx-3b is only expressed in the dorsal root ganglia...
  3. pmc BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals
    C A Jette
    Department of Pediatric Oncology, Harvard Medical School, Boston, MA 02115, USA
    Cell Death Differ 15:1063-72. 2008
    ....
  4. ncbi request reprint Myelopoiesis in the zebrafish, Danio rerio
    C M Bennett
    Department of Pediatric Oncology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Blood 98:643-51. 2001
    ..The morphologic and molecular genetic evidence presented here supports the zebrafish as an informative model system for the study of normal and aberrant human myelopoiesis. (Blood. 2001;98:643-651)..
  5. pmc Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency
    J S Blackburn
    Department of Pathology, Molecular Pathology Unit, Massachusetts General Hospital, Boston, MA, USA
    Leukemia 26:2069-78. 2012
    ..Taken together, these data indicate that a primary role of Notch signaling in T-ALL is to expand a population of pre-malignant thymocytes, of which a subset acquire the necessary mutations to become fully transformed LPCs...
  6. ncbi request reprint Conservation of steroidogenic acute regulatory (StAR) protein structure and expression in vertebrates
    M P Bauer
    Department of Biological Sciences, University of Notre Dame, PO Box 369, Notre Dame IN 46556, USA
    Mol Cell Endocrinol 168:119-25. 2000
    ..The conserved deduced protein sequence and expression pattern of StAR transcripts in chicken and zebrafish tissues, strongly suggest that StAR is also involved in the regulation of steroidogenesis in nonmammalian vertebrates...