Nicholas T Lange

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Atypical diffusion tensor hemispheric asymmetry in autism
    Nicholas Lange
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Autism Res 3:350-8. 2010
  2. pmc Associations between IQ, total and regional brain volumes, and demography in a large normative sample of healthy children and adolescents
    Nicholas Lange
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Dev Neuropsychol 35:296-317. 2010
  3. ncbi request reprint What can modern statistics offer imaging neuroscience?
    Nicholas Lange
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Stat Methods Med Res 12:447-69. 2003
  4. ncbi request reprint Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research
    Nicholas Lange
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Stat Med 23:327-50. 2004
  5. doi request reprint Age-related changes in brain energetics and phospholipid metabolism
    Brent P Forester
    Geriatric Psychiatry Research Program, McLean Hospital, Belmont, MA, USA
    NMR Biomed 23:242-50. 2010
  6. ncbi request reprint The amygdala modulates neuronal activation in the hippocampus in response to spatial novelty
    Archana Sheth
    Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    Hippocampus 18:169-81. 2008
  7. ncbi request reprint Neuron numbers and volume of the amygdala in subjects diagnosed with bipolar disorder or schizophrenia
    Sabina Berretta
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 62:884-93. 2007
  8. ncbi request reprint Individual and population penalized regression splines for accelerated longitudinal designs
    Jaroslaw Harezlak
    Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Biometrics 61:1037-48. 2005
  9. ncbi request reprint Cells in midline thalamus, central amygdala, and nucleus accumbens responding specifically to antipsychotic drugs
    Bruce M Cohen
    Molecular Pharmacology Laboratory, McLean Hospital, Department of Psychiatry, Harvard Medical School, 115 Mill Street, Belmont, MA 02478 9106, USA
    Psychopharmacology (Berl) 167:403-10. 2003
  10. pmc Functional MRI detection of pharmacologically induced memory impairment
    Reisa Sperling
    Massachusetts General Hospital, Boston, MA 02129, USA
    Proc Natl Acad Sci U S A 99:455-60. 2002

Research Grants

  1. BIOSTATISTICAL METHODS FOR HUMAN BRAIN MAPPING
    Nicholas Lange; Fiscal Year: 2006

Detail Information

Publications14

  1. pmc Atypical diffusion tensor hemispheric asymmetry in autism
    Nicholas Lange
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Autism Res 3:350-8. 2010
    ....
  2. pmc Associations between IQ, total and regional brain volumes, and demography in a large normative sample of healthy children and adolescents
    Nicholas Lange
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Dev Neuropsychol 35:296-317. 2010
    ..The relations between total and regional brain volumes and IQ can best be discerned when additional variables known to be associated with IQ, especially parental education and other demographic measures, are considered concurrently...
  3. ncbi request reprint What can modern statistics offer imaging neuroscience?
    Nicholas Lange
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Stat Methods Med Res 12:447-69. 2003
    ..Neuroscientific and fMRI background is provided for readers new to either area...
  4. ncbi request reprint Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research
    Nicholas Lange
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Stat Med 23:327-50. 2004
    ....
  5. doi request reprint Age-related changes in brain energetics and phospholipid metabolism
    Brent P Forester
    Geriatric Psychiatry Research Program, McLean Hospital, Belmont, MA, USA
    NMR Biomed 23:242-50. 2010
    ..Unlike some previous studies of aging and brain chemistry, this study examined healthy, non-demented and psychiatrically stable older adults and specifically analyzed gray-white matter differences in brain metabolism...
  6. ncbi request reprint The amygdala modulates neuronal activation in the hippocampus in response to spatial novelty
    Archana Sheth
    Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    Hippocampus 18:169-81. 2008
    ..These findings also raise the possibility that amygdala abnormalities may contribute to impairments in cognitive information processing in subjects with major psychoses...
  7. ncbi request reprint Neuron numbers and volume of the amygdala in subjects diagnosed with bipolar disorder or schizophrenia
    Sabina Berretta
    Translational Neuroscience Laboratory, McLean Hospital, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 62:884-93. 2007
    ..Growing evidence supports a pivotal role for the amygdala in the pathogenesis of bipolar disorder (BD) and schizophrenia (SZ). However, the occurrence of morphologic changes in the amygdala is currently controversial...
  8. ncbi request reprint Individual and population penalized regression splines for accelerated longitudinal designs
    Jaroslaw Harezlak
    Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Biometrics 61:1037-48. 2005
    ..Potential applications extend beyond growth studies to many other fields in which cost and feasibility constraints impose restrictions on sample size and on the numbers and timings of repeated measurements across subjects...
  9. ncbi request reprint Cells in midline thalamus, central amygdala, and nucleus accumbens responding specifically to antipsychotic drugs
    Bruce M Cohen
    Molecular Pharmacology Laboratory, McLean Hospital, Department of Psychiatry, Harvard Medical School, 115 Mill Street, Belmont, MA 02478 9106, USA
    Psychopharmacology (Berl) 167:403-10. 2003
    ....
  10. pmc Functional MRI detection of pharmacologically induced memory impairment
    Reisa Sperling
    Massachusetts General Hospital, Boston, MA 02129, USA
    Proc Natl Acad Sci U S A 99:455-60. 2002
    ....
  11. doi request reprint Extracellular matrix-glial abnormalities in the amygdala and entorhinal cortex of subjects diagnosed with schizophrenia
    Harry Pantazopoulos
    Translational Neuroscience Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA
    Arch Gen Psychiatry 67:155-66. 2010
    ....
  12. ncbi request reprint Abnormal asymmetry in language association cortex in autism
    Martha R Herbert
    Center for Morphometric Analysis, Massachusetts General Hospital, CNY 149, Room 6012, Boston, MA 02114, USA
    Ann Neurol 52:588-96. 2002
    ..In boys with autism, language and social/face processing-related regions displayed abnormal asymmetry. These structural abnormalities may relate to language and social disturbances observed in autism...
  13. ncbi request reprint Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia
    Guochuan Tsai
    Laboratory of Molecular and Psychiatric Neuroscience GT, McLean Hospital and Harvard Medical School, Boston, Massachusetts 02478, USA
    Biol Psychiatry 55:452-6. 2004
    ..N-methylglycine (sarcosine) is an endogenous antagonist of glycine transporter-1, which potentiates glycine's action on N-methyl-D-aspartate glycine site and can have beneficial effects on schizophrenia...
  14. pmc Abnormalities in mitochondrial structure in cells from patients with bipolar disorder
    Anne M Cataldo
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Am J Pathol 177:575-85. 2010
    ..The findings may have implications for diagnosis, if they are specific to BD, and for treatment, if they provide clues as to the underlying pathophysiology of BD...

Research Grants1

  1. BIOSTATISTICAL METHODS FOR HUMAN BRAIN MAPPING
    Nicholas Lange; Fiscal Year: 2006
    ..abstract_text> ..