Research Topics
| Nicholas T LangeSummaryAffiliation: Harvard University Country: USA Publications
Research Grants
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Detail Information
Publications
Atypical diffusion tensor hemispheric asymmetry in autismNicholas Lange
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Autism Res 3:350-8. 2010....
Associations between IQ, total and regional brain volumes, and demography in a large normative sample of healthy children and adolescentsNicholas Lange
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Dev Neuropsychol 35:296-317. 2010..The relations between total and regional brain volumes and IQ can best be discerned when additional variables known to be associated with IQ, especially parental education and other demographic measures, are considered concurrently...
What can modern statistics offer imaging neuroscience?Nicholas Lange
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Stat Methods Med Res 12:447-69. 2003..Neuroscientific and fMRI background is provided for readers new to either area...
Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia researchNicholas Lange
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Stat Med 23:327-50. 2004....
Age-related changes in brain energetics and phospholipid metabolismBrent P Forester
Geriatric Psychiatry Research Program, McLean Hospital, Belmont, MA, USA
NMR Biomed 23:242-50. 2010..Unlike some previous studies of aging and brain chemistry, this study examined healthy, non-demented and psychiatrically stable older adults and specifically analyzed gray-white matter differences in brain metabolism...
The amygdala modulates neuronal activation in the hippocampus in response to spatial noveltyArchana Sheth
Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
Hippocampus 18:169-81. 2008..These findings also raise the possibility that amygdala abnormalities may contribute to impairments in cognitive information processing in subjects with major psychoses...
Neuron numbers and volume of the amygdala in subjects diagnosed with bipolar disorder or schizophreniaSabina Berretta
Translational Neuroscience Laboratory, McLean Hospital, Belmont, Massachusetts 02478, USA
Biol Psychiatry 62:884-93. 2007..Growing evidence supports a pivotal role for the amygdala in the pathogenesis of bipolar disorder (BD) and schizophrenia (SZ). However, the occurrence of morphologic changes in the amygdala is currently controversial...
Individual and population penalized regression splines for accelerated longitudinal designsJaroslaw Harezlak
Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Biometrics 61:1037-48. 2005..Potential applications extend beyond growth studies to many other fields in which cost and feasibility constraints impose restrictions on sample size and on the numbers and timings of repeated measurements across subjects...
Cells in midline thalamus, central amygdala, and nucleus accumbens responding specifically to antipsychotic drugsBruce M Cohen
Molecular Pharmacology Laboratory, McLean Hospital, Department of Psychiatry, Harvard Medical School, 115 Mill Street, Belmont, MA 02478 9106, USA
Psychopharmacology (Berl) 167:403-10. 2003....
Functional MRI detection of pharmacologically induced memory impairmentReisa Sperling
Massachusetts General Hospital, Boston, MA 02129, USA
Proc Natl Acad Sci U S A 99:455-60. 2002....
Extracellular matrix-glial abnormalities in the amygdala and entorhinal cortex of subjects diagnosed with schizophreniaHarry Pantazopoulos
Translational Neuroscience Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA
Arch Gen Psychiatry 67:155-66. 2010....
Abnormal asymmetry in language association cortex in autismMartha R Herbert
Center for Morphometric Analysis, Massachusetts General Hospital, CNY 149, Room 6012, Boston, MA 02114, USA
Ann Neurol 52:588-96. 2002..In boys with autism, language and social/face processing-related regions displayed abnormal asymmetry. These structural abnormalities may relate to language and social disturbances observed in autism...
Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophreniaGuochuan Tsai
Laboratory of Molecular and Psychiatric Neuroscience (GT, McLean Hospital and Harvard Medical School, Boston, Massachusetts 02478, USA
Biol Psychiatry 55:452-6. 2004..Glycine transporter-1 is a novel target for the pharmacotherapy to enhance N-methyl-D-aspartate function...
Abnormalities in mitochondrial structure in cells from patients with bipolar disorderAnne M Cataldo
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Am J Pathol 177:575-85. 2010..The findings may have implications for diagnosis, if they are specific to BD, and for treatment, if they provide clues as to the underlying pathophysiology of BD...
Research Grants
- BIOSTATISTICAL METHODS FOR HUMAN BRAIN MAPPINGNicholas Lange; Fiscal Year: 2006..abstract_text> ..
