C R Landry

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Genome clashes in hybrids: insights from gene expression
    C R Landry
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA
    Heredity (Edinb) 99:483-93. 2007
  2. doi request reprint Systems biology spins off a new model for the study of canalization
    Christian R Landry
    Departement de Biochimie, Universite de Montreal, C P 6128, Succursale Centre Ville, Montreal, Quebec H3C 3J7, Canada
    Trends Ecol Evol 24:63-6. 2009
  3. ncbi request reprint Genetic properties influencing the evolvability of gene expression
    Christian R Landry
    Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Science 317:118-21. 2007
  4. ncbi request reprint Genome-wide scan reveals that genetic variation for transcriptional plasticity in yeast is biased towards multi-copy and dispensable genes
    Christian R Landry
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge MA, USA
    Gene 366:343-51. 2006
  5. doi request reprint Cascading transcriptional effects of a naturally occurring frameshift mutation in Saccharomyces cerevisiae
    Kyle M Brown
    Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Mol Ecol 17:2985-97. 2008
  6. pmc Alternative life histories shape brain gene expression profiles in males of the same population
    Nadia Aubin-Horth
    Bauer Center for Genomics Research, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA
    Proc Biol Sci 272:1655-62. 2005
  7. pmc Systems-level analysis and evolution of the phototransduction network in Drosophila
    Christian R Landry
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 104:3283-8. 2007
  8. ncbi request reprint Ecological and evolutionary genomics of Saccharomyces cerevisiae
    Christian R Landry
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Mol Ecol 15:575-91. 2006
  9. doi request reprint How perfect can protein interactomes be?
    Emmanuel D Levy
    Universite de Montreal, Montreal, Quebec, Canada
    Sci Signal 2:pe11. 2009
  10. pmc Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila
    Christian R Landry
    Department of Organismic and Evolutionary Biology, The Biological Laboratories, 16 Divinity Avenue, Harvard University, Cambridge, MA 02138, USA
    Genetics 171:1813-22. 2005

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Genome clashes in hybrids: insights from gene expression
    C R Landry
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA
    Heredity (Edinb) 99:483-93. 2007
    ..Finally, we consider and preview novel technologies that could help decipher how divergent transcriptional networks interact in hybrids between species...
  2. doi request reprint Systems biology spins off a new model for the study of canalization
    Christian R Landry
    Departement de Biochimie, Universite de Montreal, C P 6128, Succursale Centre Ville, Montreal, Quebec H3C 3J7, Canada
    Trends Ecol Evol 24:63-6. 2009
    ..These findings show that there is raw material for robust gene expression to evolve by natural selection, enabling the study of canalization of gene networks as it evolves in nature...
  3. ncbi request reprint Genetic properties influencing the evolvability of gene expression
    Christian R Landry
    Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Science 317:118-21. 2007
    ..These results provide a mechanistic basis for gene expression evolvability that can serve as a foundation for realistic models of regulatory evolution...
  4. ncbi request reprint Genome-wide scan reveals that genetic variation for transcriptional plasticity in yeast is biased towards multi-copy and dispensable genes
    Christian R Landry
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge MA, USA
    Gene 366:343-51. 2006
    ..We also found that genes with genetic variation for plasticity were less likely to be essential and were significantly biased towards genes that have paralogs...
  5. doi request reprint Cascading transcriptional effects of a naturally occurring frameshift mutation in Saccharomyces cerevisiae
    Kyle M Brown
    Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Mol Ecol 17:2985-97. 2008
    ....
  6. pmc Alternative life histories shape brain gene expression profiles in males of the same population
    Nadia Aubin-Horth
    Bauer Center for Genomics Research, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA
    Proc Biol Sci 272:1655-62. 2005
    ....
  7. pmc Systems-level analysis and evolution of the phototransduction network in Drosophila
    Christian R Landry
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 104:3283-8. 2007
    ..These results provide a preliminary quantification of variation and divergence of gene expression between species in a known gene network and provide a foundation for a system-level understanding of functional and evolutionary change...
  8. ncbi request reprint Ecological and evolutionary genomics of Saccharomyces cerevisiae
    Christian R Landry
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Mol Ecol 15:575-91. 2006
    ....
  9. doi request reprint How perfect can protein interactomes be?
    Emmanuel D Levy
    Universite de Montreal, Montreal, Quebec, Canada
    Sci Signal 2:pe11. 2009
    ..Finally, we propose experimental strategies to estimate the fraction of evolutionary noise in PPI networks...
  10. pmc Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila
    Christian R Landry
    Department of Organismic and Evolutionary Biology, The Biological Laboratories, 16 Divinity Avenue, Harvard University, Cambridge, MA 02138, USA
    Genetics 171:1813-22. 2005
    ..Using a mathematical model for the regulation of gene expression, we explored the conditions under which cis-trans compensatory evolution can lead to misexpression in interspecific hybrids...
  11. doi request reprint An in vivo map of the yeast protein interactome
    Kirill Tarassov
    Departement de Biochimie, Université de Montréal Casier postal 6128, Succursale Centre Ville, Montreal, Quebec H3C 3J7, Canada
    Science 320:1465-70. 2008
    ....
  12. ncbi request reprint Indel arrays: an affordable alternative for genotyping
    Neeraj Salathia
    FAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA
    Plant J 51:727-37. 2007
    ..Given the ease of use of shotgun sequencing to generate partial genomic sequences of unsequenced species, this approach is readily transferable to non-model organisms...
  13. doi request reprint Weak functional constraints on phosphoproteomes
    Christian R Landry
    Centre Robert Cedergren, Bio Informatique et Génomique, Departement de Biochimie, C P 6128, Succ Centre Ville, Montreal, Quebec H3C 3J7, Canada
    Trends Genet 25:193-7. 2009
    ..Our findings highlight the need to use evolutionary information to identify functional regulatory features such as post-translational modifications of eukaryotic proteomes...
  14. pmc Large-scale genetic variation of the symbiosis-required megaplasmid pSymA revealed by comparative genomic analysis of Sinorhizobium meliloti natural strains
    Elisa Giuntini
    Dipartimento di Biologia Animale e Genetica, Universita di Firenze, Via Romana 17, I 50125 Firenze, Italy
    BMC Genomics 6:158. 2005
    ....
  15. pmc A genome-wide view of the spectrum of spontaneous mutations in yeast
    Michael Lynch
    Department of Biology, Indiana University, Bloomington, IN 47405, USA
    Proc Natl Acad Sci U S A 105:9272-7. 2008
    ....
  16. ncbi request reprint Ecological annotation of genes and genomes through ecological genomics
    Christian R Landry
    Mol Ecol 16:4419-21. 2007
    ..Through their research on a diverse array of organisms, the various speakers illustrated how ecology and evolution benefit from genomics, and indirectly how genomics can benefit from evolutionary ecology...