M B Landrum

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Reasons for underuse of recommended therapies for colorectal and lung cancer in the Veterans Health Administration
    Mary Beth Landrum
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 118:3345-55. 2012
  2. ncbi Survival of older patients with cancer in the Veterans Health Administration versus fee-for-service Medicare
    Mary Beth Landrum
    Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 30:1072-9. 2012
  3. ncbi The effect on survival of continuing chemotherapy to near death
    Akiko M Saito
    Health Services Research Program, Cancer Care Ontario and the Ontario Institute for Cancer Research, Toronto, ON, Canada
    BMC Palliat Care 10:14. 2011
  4. ncbi Is spending more always wasteful? The appropriateness of care and outcomes among colorectal cancer patients
    Mary Beth Landrum
    Harvard Medical School, Boston, Massachusetts, USA
    Health Aff (Millwood) 27:159-68. 2008
  5. ncbi Applying Bayesian ideas to the development of medical guidelines
    M B Landrum
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Stat Med 18:117-37. 1999
  6. ncbi A multiple imputation strategy for incomplete longitudinal data
    M B Landrum
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, U S A
    Stat Med 20:2741-60. 2001
  7. ncbi Impact of underuse, overuse, and discretionary use on geographic variation in the use of coronary angiography after acute myocardial infarction
    E Guadagnoli
    Department of Health Care Policy, Harvard Medical School, Boston MA 02115 5899, USA
    Med Care 39:446-58. 2001
  8. ncbi Validating recommendations for coronary angiography following acute myocardial infarction in the elderly: a matched analysis using propensity scores
    S T Normand
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115 5899, USA
    J Clin Epidemiol 54:387-98. 2001
  9. ncbi Appropriateness of coronary angiography after myocardial infarction among Medicare beneficiaries. Managed care versus fee for service
    E Guadagnoli
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115 5899, USA
    N Engl J Med 343:1460-6. 2000
  10. ncbi Managed care market share and primary treatment for cancer
    Nancy L Keating
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Health Serv Res 41:9-22. 2006

Research Grants

  1. Use of Geographic Variations to Estimate Effectiveness with Non-Randomized Data
    Mary Beth Landrum; Fiscal Year: 2010

Detail Information

Publications55

  1. ncbi Reasons for underuse of recommended therapies for colorectal and lung cancer in the Veterans Health Administration
    Mary Beth Landrum
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 118:3345-55. 2012
    ..Many studies have documented low rates of effective cancer therapies, particularly in older or minority populations. However, little is known about why effective therapies are underused in these populations...
  2. ncbi Survival of older patients with cancer in the Veterans Health Administration versus fee-for-service Medicare
    Mary Beth Landrum
    Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 30:1072-9. 2012
    ....
  3. ncbi The effect on survival of continuing chemotherapy to near death
    Akiko M Saito
    Health Services Research Program, Cancer Care Ontario and the Ontario Institute for Cancer Research, Toronto, ON, Canada
    BMC Palliat Care 10:14. 2011
    ..abstract:..
  4. ncbi Is spending more always wasteful? The appropriateness of care and outcomes among colorectal cancer patients
    Mary Beth Landrum
    Harvard Medical School, Boston, Massachusetts, USA
    Health Aff (Millwood) 27:159-68. 2008
    ..Our results show that instead of cutting spending, policies designed to target services to patients most likely to benefit could increase the value of medical spending...
  5. ncbi Applying Bayesian ideas to the development of medical guidelines
    M B Landrum
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Stat Med 18:117-37. 1999
    ....
  6. ncbi A multiple imputation strategy for incomplete longitudinal data
    M B Landrum
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, U S A
    Stat Med 20:2741-60. 2001
    ..Extensions to other missing data problems in longitudinal studies are straightforward so long as the missing data mechanism can be assumed to be ignorable...
  7. ncbi Impact of underuse, overuse, and discretionary use on geographic variation in the use of coronary angiography after acute myocardial infarction
    E Guadagnoli
    Department of Health Care Policy, Harvard Medical School, Boston MA 02115 5899, USA
    Med Care 39:446-58. 2001
    ..Geographic variation in the use of medical procedures has been well documented. However, it is not known whether this variation is due to differences in use when procedures are indicated, discretionary, or contraindicated...
  8. ncbi Validating recommendations for coronary angiography following acute myocardial infarction in the elderly: a matched analysis using propensity scores
    S T Normand
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115 5899, USA
    J Clin Epidemiol 54:387-98. 2001
    ..Because of the magnitude of the benefit and of the number of patients involved, steps should be taken to replicate these findings...
  9. ncbi Appropriateness of coronary angiography after myocardial infarction among Medicare beneficiaries. Managed care versus fee for service
    E Guadagnoli
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115 5899, USA
    N Engl J Med 343:1460-6. 2000
    ..However, it is not known whether this difference is due to less frequent use of cardiac procedures when they are indicated or to less frequent use when they are not indicated...
  10. ncbi Managed care market share and primary treatment for cancer
    Nancy L Keating
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Health Serv Res 41:9-22. 2006
    ..30). CONCLUSIONS: Increases in the market share of managed care do not appear to influence the receipt of equally effective primary treatments for cancer in the fee-for-service sector...
  11. ncbi Aggressiveness of cancer care near the end of life: is it a quality-of-care issue?
    Craig C Earle
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    J Clin Oncol 26:3860-6. 2008
    ..Whether the concept of overly aggressive treatment represents a quality-of-care issue that is acceptable to all involved stakeholders is an open question...
  12. ncbi Variations in surgeon treatment recommendations for lobectomy in early-stage non-small-cell lung cancer by patient age and comorbidity
    Selwyn O Rogers
    Department of Surgery and Center for Surgery and Public Health, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg Oncol 17:1581-8. 2010
    ..We surveyed surgeons to understand how their recommendations for lobectomy were influenced by age, the presence and severity of smoking-related lung disease, or by characteristics of the surgeons and their practices...
  13. ncbi Multiple imputation in a large-scale complex survey: a practical guide
    Y He
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    Stat Methods Med Res 19:653-70. 2010
    ..We present the implementation process in detail as an example for practitioners and discuss some of the challenging issues which need further research...
  14. ncbi Discussion of treatment options for early-stage breast cancer: effect of provider specialty on type of surgery and satisfaction
    N L Keating
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Med Care 39:681-91. 2001
    ..To describe the physicians with whom breast cancer patients discuss treatment options and assess whether discussing surgical options with a medical oncologist is associated with type of surgery and satisfaction...
  15. ncbi Understanding individual and small area variation in the underuse of coronary angiography following acute myocardial infarction
    Pushkal P Garg
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115-5899, USA
    Med Care 40:614-26. 2002
    ..The causes of regional variation in underuse do not appear to be related to regional differences in patient or hospital characteristics, and therefore, require further study...
  16. ncbi Differences in clinical trial patient attributes and outcomes according to enrollment setting
    Elizabeth B Lamont
    Dept of Health Care Policy, Harvard Medical School, 180A Longwood Ave, Boston, MA 02115, USA
    J Clin Oncol 28:215-21. 2010
    ..We compared trial patients' attributes and outcomes by these enrollment settings...
  17. ncbi Physical and mental health status of older long-term cancer survivors
    Nancy L Keating
    Division of General Internal Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Am Geriatr Soc 53:2145-52. 2005
    ..To assess the physical and mental health status of older long-term cancer survivors...
  18. ncbi The influence of physicians' practice management strategies and financial arrangements on quality of care among patients with diabetes
    Nancy L Keating
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    Med Care 42:829-39. 2004
    ..Health care organizations use many strategies to influence physician behavior and the care delivered, but the effect of such strategies on quality is not known...
  19. ncbi Surveillance testing among survivors of early-stage breast cancer
    Nancy L Keating
    Division of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Oncol 25:1074-81. 2007
    ..We described follow-up care for breast cancer survivors, examined how surveillance testing varies by the types of physicians seen, and assessed changes in testing rates over time...
  20. ncbi The influence of cost containment strategies and physicians' financial arrangements on patients' trust and satisfaction
    Nancy L Keating
    Division of General Internal Medicine, Brigham and Women s Hospital, MA, USA
    J Ambul Care Manage 30:92-104. 2007
    ..These results suggest that physicians may have managed potential conflicts to avoid compromising the patient-physician relationship...
  21. ncbi Quality of care in a Medicaid population with bipolar I disorder
    Alisa B Busch
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
    Psychiatr Serv 58:848-54. 2007
    ..This study examined whether presenting diagnosis and treatment in intensive settings (hospitalization, partial hospitalization, or residential programs) are correlated with the subsequent treatment of bipolar I disorder...
  22. ncbi Adjuvant chemotherapy for stage III colon cancer: do physicians agree about the importance of patient age and comorbidity?
    Nancy L Keating
    Division of General Internal Medicine and the Department of Surgery and Center for Surgery and Public Health, Brigham and Women s Hospital, USA
    J Clin Oncol 26:2532-7. 2008
    ..We surveyed cancer physicians to understand how patients' age and comorbidity influence adjuvant chemotherapy recommendations and whether physician or practice characteristics also affect these recommendations...
  23. ncbi Care in the months before death and hospice enrollment among older women with advanced breast cancer
    Nancy L Keating
    Division of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    J Gen Intern Med 23:11-8. 2008
    ..Variations in hospice use are not well understood...
  24. ncbi End-of-life care for older cancer patients in the Veterans Health Administration versus the private sector
    Nancy L Keating
    The Division of General Internal Medicine, Brigham and Women s Hospital, Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 116:3732-9. 2010
    ..We compared aggressiveness of end-of-life care of older metastatic cancer patients treated in the Veterans Health Administration (VHA) and those under fee-for-service Medicare arrangements...
  25. ncbi Outcomes following local therapy for early-stage breast cancer in non-trial populations
    Nancy L Keating
    Division of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Breast Cancer Res Treat 125:803-13. 2011
    ..These findings are reassuring in light of recent trends towards more aggressive primary breast cancer therapy...
  26. ncbi Physician factors associated with discussions about end-of-life care
    Nancy L Keating
    Division of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Cancer 116:998-1006. 2010
    ..Guidelines recommend advanced care planning for terminally ill patients with <1 year to live. Few data are available regarding when physicians and their terminally ill patients typically discuss end-of-life issues...
  27. ncbi Does oral antiandrogen use before leuteinizing hormone-releasing hormone therapy in patients with metastatic prostate cancer prevent clinical consequences of a testosterone flare?
    William K Oh
    Lank Center for Genitourinary Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Urology 75:642-7. 2010
    ..LHRH agonists are associated with initial testosterone rises that may cause clinical disease flares in men with metastatic prostate cancer...
  28. ncbi Factors related to underuse of surveillance mammography among breast cancer survivors
    Nancy L Keating
    Division of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    J Clin Oncol 24:85-94. 2006
    ..We identified factors associated with underuse of surveillance mammography and examined whether variation was explained by differences in follow-up care...
  29. ncbi Evaluating claims-based indicators of the intensity of end-of-life cancer care
    Craig C Earle
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Qual Health Care 17:505-9. 2005
    ..To evaluate measures that could use existing administrative data to assess the intensity of end-of-life cancer care...
  30. ncbi Physician specialization and the quality of care for human immunodeficiency virus infection
    Bruce E Landon
    Division of General Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Arch Intern Med 165:1133-9. 2005
    ..We sought to assess the relationship between specialty training and expertise and the quality of care delivered to patients with HIV infection...
  31. ncbi Use of cholesterol-lowering therapy and related beliefs among middle-aged adults after myocardial infarction
    John Z Ayanian
    Department of Medicine, Division of General Medicine and Primary Care, Brigham and Women s Hospital and Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, USA
    J Gen Intern Med 17:95-102. 2002
    ..To assess use of cholesterol-lowering therapy and related beliefs among middle-aged adults after myocardial infarction...
  32. ncbi Treatment decision making in early-stage breast cancer: should surgeons match patients' desired level of involvement?
    Nancy L Keating
    Division of General Internal Medicine, Section on Health Services and Policy Research, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    J Clin Oncol 20:1473-9. 2002
    ....
  33. ncbi Use of cholesterol-lowering therapy by elderly adults after myocardial infarction
    John Z Ayanian
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 162:1013-9. 2002
    ..Use of cholesterol-lowering drugs reduces mortality and adverse cardiac events among people aged 65 to 75 years with coronary heart disease, but previous studies have shown that most patients have not received this treatment...
  34. ncbi Specialty of ambulatory care physicians and mortality among elderly patients after myocardial infarction
    John Z Ayanian
    Department of Medicine, Division of General Medicine and Primary Care, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 347:1678-86. 2002
    ..The outcome after myocardial infarction may be influenced by the type of physician providing ambulatory care...
  35. ncbi Consultation with a medical oncologist before surgery and type of surgery among elderly women with early-stage breast cancer
    Nancy L Keating
    Department of Medicine, Brigham and Women s Hospital, and Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 21:4532-9. 2003
    ..We assessed whether consultation with a medical oncologist before surgery was associated with use of definitive surgery, axillary node dissection, and type of surgery...
  36. ncbi Trends in the aggressiveness of cancer care near the end of life
    Craig C Earle
    MSc, Center for Outcomes and Policy Research, Dana Farber Cancer Center, 44 Binney St, 454 STE 21 24, Boston, MA 02115, USA
    J Clin Oncol 22:315-21. 2004
    ..To characterize the aggressiveness of end-of-life cancer treatment for older adults on Medicare, and its relationship to the availability of healthcare resources...
  37. ncbi Effects of a quality improvement collaborative on the outcome of care of patients with HIV infection: the EQHIV study
    Bruce E Landon
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
    Ann Intern Med 140:887-96. 2004
    ..Multi-institution collaborative quality improvement programs are a well-established and broadly applicable quality improvement strategy, but there is little systematic assessment their effectiveness...
  38. ncbi The association of ambulatory care with breast cancer stage at diagnosis among Medicare beneficiaries
    Nancy L Keating
    Division of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    J Gen Intern Med 20:38-44. 2005
    ..We examined outpatient care in the 2 years before breast cancer diagnosis to identify women at high risk for limited care and assess the relationship of the physicians seen and number of visits with stage at diagnosis...
  39. ncbi Do increases in the market share of managed care influence quality of cancer care in the fee-for-service sector?
    Nancy L Keating
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    J Natl Cancer Inst 97:257-64. 2005
    ....
  40. ncbi The effect of managed care market share on appropriate use of coronary angiography among traditional Medicare beneficiaries
    Ellen Meara
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115 5899, USA
    Inquiry 41:144-58. 2004
    ..Within all ACC-AHA classes, coronary angiography fell slightly as managed care market share increased...
  41. ncbi Quality of ambulatory care after myocardial infarction among Medicare patients by type of insurance and region
    M E Seddon
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA
    Am J Med 111:24-32. 2001
    ..Future studies should assess the quality of ambulatory cardiac care in different types of HMOs and the reasons for geographic variations in cardiac drug use...
  42. ncbi Measuring the quality of diabetes care using administrative data: is there bias?
    Nancy L Keating
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Health Serv Res 38:1529-45. 2003
    ..We assessed whether measuring processes of diabetes care using administrative data without medical record data is likely to underdetect compliance with accepted standards for certain groups of patients...
  43. ncbi Using performance data to identify preferred hospitals
    Meredith B Rosenthal
    Department of Health Policy and Management, Harvard School of Public Health, 677 Huntington Avenue, Room 405, Boston, MA 02115, USA
    Health Serv Res 42:2109-19; discussion 2294-323. 2007
    ..To explore the implications of current approaches used by health plans and purchasers to identify preferred hospitals for tiered networks using cost and quality information...
  44. ncbi Care following acute myocardial infarction in the Veterans Administration Medical Centers: a comparison with Medicare
    Mary Beth Landrum
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02110, USA
    Health Serv Res 39:1773-92. 2004
    ..Further study of these differences both between and within the systems of care may help identify cost-effective strategies to improve care in both sectors...
  45. ncbi Quality of care provided to individual patients in US hospitals: results from an analysis of national Hospital Quality Alliance data
    Christine Vogeli
    Department of Medicine, MGH Institute for Health Policy, 50 Staniford Street, Boston, MA 02114, USA
    Med Care 47:591-9. 2009
    ..3 million individuals receiving care in non-federal US hospitals in 2005. MEASURES: The proportion of patients who received all applicable care processes, and the mean proportion of applicable processes received by hospitalized patients...
  46. ncbi The treating physician as active gatekeeper in the recruitment of research subjects
    J H Gurwitz
    Meyers Primary Care Institute, Worcester, Massachusetts, USA
    Med Care 39:1339-44. 2001
    ..Institutional Review Boards vary in regard to the conditions imposed on investigators concerning contacting potential subjects to participate in health-services research studies...
  47. ncbi The effect of three-tier formulary adoption on medication continuation and spending among elderly retirees
    Haiden A Huskamp
    Harvard Medical School, Department of Health Care Policy, 180 Longwood Avenue, Boston, MA 02115, USA
    Health Serv Res 42:1926-42. 2007
    ..To assess the effect of three-tier formulary adoption on medication continuation and spending among elderly members of retiree health plans...
  48. ncbi Adjuvant tamoxifen prescription in women 65 years and older with primary breast cancer
    Rebecca A Silliman
    Department of Medicine, Boston University School of Medicine, MA, USA
    J Clin Oncol 20:2680-8. 2002
    ..We examined patterns of adjuvant tamoxifen discussion and prescription among breast cancer patients age 65 years and older...
  49. ncbi Relationship of diabetes-specific knowledge to self-management activities, ambulatory preventive care, and metabolic outcomes
    Stephen D Persell
    Division of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Prev Med 39:746-52. 2004
    ..Providing patient education about diabetes care processes should be tested as a means of increasing ambulatory care to prevent diabetes complications...
  50. ncbi Longitudinal profiles of health care providers
    Susan E Bronskill
    Department of Health Policy, Management and Evaluation, University of Toronto, Ontario, Canada
    Stat Med 21:1067-88. 2002
    ..Furthermore, the longitudinal profiles developed are easily interpreted and flexible, making them of practical use to policy-makers...
  51. ncbi The economic impacts of the tobacco settlement
    David M Cutler
    Department of Economics, Harvard University, USA
    J Policy Anal Manage 21:1-19. 2002
    ..To the extent that the value of the health benefits is not offset by the value of the pleasure foregone, the economic impacts of the MSA will include a share of these health benefits...
  52. ncbi ACC/AHA clinical performance measures for adults with ST-elevation and non-ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures (Writing Committee to Develop Perfo
    Harlan M Krumholz
    J Am Coll Cardiol 47:236-65. 2006
  53. ncbi Breast cancer in older women: quality of life and psychosocial adjustment in the 15 months after diagnosis
    Patricia A Ganz
    University of California, School of Medicine and Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, Los Angeles, 90095 6900, USA
    J Clin Oncol 21:4027-33. 2003
    ..We examined the health-related quality of life (QOL) of a cohort of older women with breast cancer after their diagnosis...
  54. ncbi ACC/AHA clinical performance measures for adults with ST-elevation and non-ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures (Writing Committee to Develop Perfo
    Harlan M Krumholz
    Circulation 113:732-61. 2006
  55. ncbi Disparities in health care are driven by where minority patients seek care: examination of the hospital quality alliance measures
    Romana Hasnain-Wynia
    Health Research and Educational Trust, American Hospital Association, and Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60606, USA
    Arch Intern Med 167:1233-9. 2007
    ..We assessed racial/ethnic disparities using the Hospital Quality Alliance Inpatient Quality of Care Indicators...

Research Grants1

  1. Use of Geographic Variations to Estimate Effectiveness with Non-Randomized Data
    Mary Beth Landrum; Fiscal Year: 2010
    ..In addition, the methods developed will be applicable to a broad range of interventions for cancer and other diseases, providing a framework for future comparative effectiveness studies and ultimately changes in treatment guidelines. ..