Research Topics
Species | Marc LallemantSummaryAffiliation: Harvard School of Public Health Country: USA Publications
Research Grants
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Detail Information
Publications
Influence of body weight on achieving indinavir concentrations within its therapeutic window in HIV-infected Thai patients receiving indinavir boosted with ritonavirTim R Cressey
Program for HIV Prevention and Treatment IRD URI 174, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand
Ther Drug Monit 33:25-31. 2011..The risk of toxic drug concentrations increases rapidly with IDV/r dose of 600/100 mg for patients less than 50 kg and therapeutic drug monitoring of IDV concentrations would help to reduce the risk of IDV-induced nephrotoxicity...
Single-dose perinatal nevirapine plus standard zidovudine to prevent mother-to-child transmission of HIV-1 in ThailandMarc Lallemant
Epidemiologie Clinique, Sante Maternelle et Infantile et Sida, Institut de Recherche pour le Developpement, Paris
N Engl J Med 351:217-28. 2004..We hypothesized that the administration, in addition to zidovudine, of a single dose of oral nevirapine to mothers during labor and to neonates would further reduce transmission of HIV...- Efficacy and safety of 1-month postpartum zidovudine-didanosine to prevent HIV-resistance mutations after intrapartum single-dose nevirapineMarc Lallemant
Institut de Recherche pour le Développement U174, Universite Paris Descartes, Institut National d Etudes Demographiques, Institut de Recherche pour le Developpment, F 75006, Paris, France
Clin Infect Dis 50:898-908. 2010..We hypothesized that a 1-month zidovudine-didanosine course initiated at the same time as single-dose nevirapine (sdNVP) would prevent the selection of nevirapine-resistance mutations... - Risk factors for in utero or intrapartum mother-to-child transmission of human immunodeficiency virus type 1 in ThailandGonzague Jourdain
Institut de Recherche pour le Developpement, UMI 174 Epidemiologie Clinique, Sante Maternelle et Infantile et Sida, Paris, France
J Infect Dis 196:1629-36. 2007..The identification of risk factors for in utero and intrapartum transmission of human immunodeficiency virus type 1 (HIV-1) is crucial to the design and understanding of preventive interventions... - Perinatal zidovudine prophylaxis in HIV type-1-infected pregnant women with thalassaemia carriage in ThailandNelly Briand
Institut National d Etudes Demographiques, Paris, France
Antivir Ther 14:117-22. 2009.... - Hematological safety of perinatal exposure to zidovudine in uninfected infants born to HIV type 1-infected women in ThailandNelly Briand
Institut National d Etudes Démographiques INED, Paris, France
AIDS Res Hum Retroviruses 26:1163-6. 2010..Despite the differences in hemoglobin levels, grade 3 or 4 anemia did not significantly differ by maternal or infant zidovudine duration. The clinical impact appeared modest, but longer exposure may warrant close monitoring... - Long-term survival of HIV-infected children receiving antiretroviral therapy in Thailand: a 5-year observational cohort studyIntira J Collins
Institut de Recherche pour le Développement IRD U174, Paris, France
Clin Infect Dis 51:1449-57. 2010..There are scarce data on the long-term survival of human immunodeficiency virus (HIV)-infected children receiving antiretroviral therapy (ART) in lower-middle income countries beyond 2 years of follow-up... - Growth of human immunodeficiency virus-uninfected children exposed to perinatal zidovudine for the prevention of mother-to-child human immunodeficiency virus transmissionNelly Briand
, Paris, France
Pediatr Infect Dis J 25:325-32. 2006..Neither the total nor the postnatal duration of exposure was associated with changes in infant Z-scores from 6 weeks to 18 months of age... 
Association of low CD4 cell count and intrauterine growth retardation in ThailandJohann Cailhol
Institut de Recherche pour le Developpement, Paris, France UMI 174
J Acquir Immune Defic Syndr 50:409-13. 2009..Some studies have suggested that HIV infection could increase the risk of IUGR. To confirm this hypothesis, we examined the association between HIV-related factors and the risk of IUGR in Thailand...- Laboratory and clinical predictors of disease progression following initiation of combination therapy in HIV-infected adults in ThailandTrinh Duong
Institut de Recherche pour le Developpement, IRD UMI 174, Paris, France
PLoS ONE 7:e43375. 2012..Data on determinants of long-term disease progression in HIV-infected patients on antiretroviral therapy (ART) are limited in low and middle-income settings... - Early HIV-1 diagnosis using in-house real-time PCR amplification on dried blood spots for infants in remote and resource-limited settingsNicole Ngo-Giang-Huong
département Sociétés et Santé, Institut de Recherche pour le Developpement, U174 Program for HIV Prevention and Treatment, Chiang Mai, Thailand
J Acquir Immune Defic Syndr 49:465-71. 2008..In resource-limited settings, most perinatally HIV-1-infected infants do not receive timely antiretroviral therapy because early HIV-1 diagnosis is not available or affordable... - Pharmacogenetics of antiretroviral drugs for the treatment of HIV-infected patients: an updateTim R Cressey
Harvard School of Public Health, Boston, MA, USA
Infect Genet Evol 7:333-42. 2007.... - Human immunodeficiency virus-hepatitis C virus co-infection in pregnant women and perinatal transmission to infants in ThailandNicole Ngo-Giang-Huong
Institut de recherche pour le developpement IRD, U174 Program for HIV Prevention and Treatment PHPT, Faculty of Associated Medical Sciences, Department of Medical Technology, 110 Inthawaroros Road, Muang, 50200 Chiang Mai, Thailand
Int J Infect Dis 14:e602-7. 2010.... - Low-doses of indinavir boosted with ritonavir in HIV-infected Thai patients: pharmacokinetics, efficacy and tolerabilityTim R Cressey
Harvard School of Public Health, Harvard University, Boston, MA, USA
J Antimicrob Chemother 55:1041-4. 2005..To assess the steady-state pharmacokinetics of two reduced doses of indinavir boosted with ritonavir (indinavir/ritonavir) in HIV-infected Thai patients... - Pharmacokinetics and virologic response of zidovudine/lopinavir/ritonavir initiated during the third trimester of pregnancyTim R Cressey
Department of Medical Technology, Chiang Mai University, Thailand
AIDS 24:2193-200. 2010.... - Intrapartum exposure to nevirapine and subsequent maternal responses to nevirapine-based antiretroviral therapyGonzague Jourdain
Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, USA
N Engl J Med 351:229-40. 2004..Whether there are clinically significant consequences in mothers who are subsequently treated with a nevirapine-containing regimen is unknown... - Early postpartum pharmacokinetics of lopinavir initiated intrapartum in Thai womenTim R Cressey
Harvard School of Public Health, Boston, Massachusetts, USA
Antimicrob Agents Chemother 53:2189-91. 2009..2 (8.0 to 17.5) microg/ml, and 4.6 (1.7 to 12.5) microg/ml, respectively, at 41 (12 to 74) h after delivery. All of the women attained adequate LPV levels through 30 days postpartum. No serious adverse events were reported... - Persistence of nevirapine exposure during the postpartum period after intrapartum single-dose nevirapine in addition to zidovudine prophylaxis for the prevention of mother-to-child transmission of HIV-1Tim R Cressey
Harvard School of Public Health, Boston, MA, USA
J Acquir Immune Defic Syndr 38:283-8. 2005..To determine nevirapine (NVP) plasma levels during the postpartum period after a single intrapartum NVP dose for the prevention of mother-to-child transmission...
Research Grants
- Monitoring HAART in HIV-infected parents in ThailandMarc Lallemant; Fiscal Year: 2007..A secondary endpoint is the number of drugs exhausted, taking into account cross-resistance mutations and shared toxicities. A pilot pharmacokinetic sub study will evaluate drug levels in the study population. ..
- Lopinavir/ritonavir + zidovudine to prevent perinatal HIV in ThailandMarc J Lallemant; Fiscal Year: 2010....
- Standard zidovudine plus infant nevirapine to prevent perinatal HIV in ThailandMarc Lallemant; Fiscal Year: 2009....
- Lopinavir/ritonavir + zidovudine to prevent perinatal HIV in ThailandMarc Lallemant; Fiscal Year: 2009....
- Lopinavir/ritonavir + zidovudine to prevent perinatal HIV in ThailandMarc Lallemant; Fiscal Year: 2007....
- Standard zidovudine plus infant nevirapine to prevent perinatal HIV in ThailandMarc Lallemant; Fiscal Year: 2007....
- Program for HIV Prevention and Treatment-Clinical Trial Unit, ThailandMarc Lallemant; Fiscal Year: 2007..It will also strengthen the expertise of the health care workers participating in the research in Thailand, and the knowledge produced will improve the care given in all affected areas. ADMINISTRATIVE COMPONENT: ..
- NEVIRAPINE+ZIDOVUDINE--PREVENT PERINATAL HIV IN THAILANDMarc Lallemant; Fiscal Year: 2002....
- Standard zidovudine plus infant nevirapine to prevent perinatal HIV in ThailandMarc J Lallemant; Fiscal Year: 2010....