Alvaro C Laga

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Expression of the embryonic stem cell transcription factor SOX2 in human skin: relevance to melanocyte and merkel cell biology
    Alvaro C Laga
    Department of Pathology, Program in Dermatopathology, Boston, MA 02115, USA
    Am J Pathol 176:903-13. 2010
  2. doi request reprint Cellular heterogeneity in vertical growth phase melanoma
    Alvaro C Laga
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Arch Pathol Lab Med 134:1750-7. 2010
  3. pmc SOX2 contributes to melanoma cell invasion
    Sasha D Girouard
    Program in Dermatopathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Lab Invest 92:362-70. 2012
  4. pmc 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies
    Jonathan J Lee
    Program in Dermatopathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Mod Pathol 28:218-29. 2015
  5. pmc SOX2 and nestin expression in human melanoma: an immunohistochemical and experimental study
    Alvaro C Laga
    Department of Pathology, Program in Dermatopathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Exp Dermatol 20:339-45. 2011
  6. doi request reprint Biomarker evaluation of face transplant rejection: association of donor T cells with target cell injury
    Christine Guo Lian
    Division of Dermatopathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Mod Pathol 27:788-99. 2014
  7. doi request reprint Histopathologic spectrum of psoriasiform skin reactions associated with tumor necrosis factor-α inhibitor therapy. A study of 16 biopsies
    Alvaro C Laga
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Dermatopathol 32:568-73. 2010
  8. doi request reprint Utility of acid-fast staining for detection of mycobacteria in cutaneous granulomatous tissue reactions
    Alvaro C Laga
    Dept of Pathology, 75 Francis St, Boston, MA 02115
    Am J Clin Pathol 141:584-6. 2014
  9. doi request reprint Cutaneous gnathostomiasis: report of 6 cases with emphasis on histopathological demonstration of the larva
    Alvaro C Laga
    Program in Dermatopathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Acad Dermatol 68:301-5. 2013

Collaborators

Detail Information

Publications9

  1. pmc Expression of the embryonic stem cell transcription factor SOX2 in human skin: relevance to melanocyte and merkel cell biology
    Alvaro C Laga
    Department of Pathology, Program in Dermatopathology, Boston, MA 02115, USA
    Am J Pathol 176:903-13. 2010
    ..In aggregate, these findings suggest that SOX2 is a novel biomarker for subpopulations of normal skin cells that reside in established stem cell niches and that might relate to Merkel cell and melanocyte ontogeny and tumorigenesis...
  2. doi request reprint Cellular heterogeneity in vertical growth phase melanoma
    Alvaro C Laga
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Arch Pathol Lab Med 134:1750-7. 2010
    ..At a considerably small tumor size, it incurs significant risk for widespread metastatic dissemination. There are no effective means of surgical intervention, chemical therapy, or immunologic therapy for advanced and metastatic melanoma...
  3. pmc SOX2 contributes to melanoma cell invasion
    Sasha D Girouard
    Program in Dermatopathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Lab Invest 92:362-70. 2012
    ..These data implicate SOX2 expression in melanoma invasion, and suggest a role for MMP-3 as one potential mediator of this process...
  4. pmc 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies
    Jonathan J Lee
    Program in Dermatopathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Mod Pathol 28:218-29. 2015
    ..Thus, 5-hydroxymethylcytosine may be a useful adjunctive marker to distinguish between benign nodal nevi and metastatic melanoma during the evaluation of sentinel lymph node biopsies for metastatic melanoma. ..
  5. pmc SOX2 and nestin expression in human melanoma: an immunohistochemical and experimental study
    Alvaro C Laga
    Department of Pathology, Program in Dermatopathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Exp Dermatol 20:339-45. 2011
    ..In aggregate, these data further support a biologically significant linkage between SOX2 and nestin expression in human melanoma...
  6. doi request reprint Biomarker evaluation of face transplant rejection: association of donor T cells with target cell injury
    Christine Guo Lian
    Division of Dermatopathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Mod Pathol 27:788-99. 2014
    ..A more histopathologically refined and immune-based biomarker approach to assessment of rejection of facial transplants is now indicated. ..
  7. doi request reprint Histopathologic spectrum of psoriasiform skin reactions associated with tumor necrosis factor-α inhibitor therapy. A study of 16 biopsies
    Alvaro C Laga
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Dermatopathol 32:568-73. 2010
    ..Because the different histopathologic findings may be subtle, clinical correlation is crucial to make the diagnosis...
  8. doi request reprint Utility of acid-fast staining for detection of mycobacteria in cutaneous granulomatous tissue reactions
    Alvaro C Laga
    Dept of Pathology, 75 Francis St, Boston, MA 02115
    Am J Clin Pathol 141:584-6. 2014
    ..We sought to investigate the utility of performing acid-fast stains (AFS) on skin biopsy specimens with granulomatous inflammation without an otherwise obvious histologic or clinical explanation...
  9. doi request reprint Cutaneous gnathostomiasis: report of 6 cases with emphasis on histopathological demonstration of the larva
    Alvaro C Laga
    Program in Dermatopathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Acad Dermatol 68:301-5. 2013
    ..Cutaneous gnathostomiasis is an emerging food-borne parasitic zoonosis. Histopathological demonstration of the larva on random biopsy specimen of erythematous plaques is infrequent because of its migrating nature...