Kenneth K Kwong

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Record of a single fMRI experiment in May of 1991
    Kenneth K Kwong
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA
    Neuroimage 62:610-2. 2012
  2. pmc Early time points perfusion imaging
    Kenneth K Kwong
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 54:1070-82. 2011
  3. pmc Early time points perfusion imaging: theoretical analysis of correction factors for relative cerebral blood flow estimation given local arterial input function
    Kenneth K Kwong
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 57:182-9. 2011
  4. pmc Early time points perfusion imaging: relative time of arrival, maximum derivatives and fractional derivatives
    Kenneth K Kwong
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 57:979-90. 2011
  5. pmc Acupuncture mobilizes the brain's default mode and its anti-correlated network in healthy subjects
    Kathleen K S Hui
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129, USA
    Brain Res 1287:84-103. 2009
  6. pmc Acupuncture, the limbic system, and the anticorrelated networks of the brain
    Kathleen K S Hui
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA
    Auton Neurosci 157:81-90. 2010
  7. pmc Time-variant fMRI activity in the brainstem and higher structures in response to acupuncture
    Vitaly Napadow
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 47:289-301. 2009
  8. ncbi request reprint Somatosensory cortical plasticity in carpal tunnel syndrome treated by acupuncture
    Vitaly Napadow
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Hum Brain Mapp 28:159-71. 2007
  9. pmc Electrical stimulation modulates the amphetamine-induced hemodynamic changes: an fMRI study to compare the effect of stimulating locations and frequencies on rats
    Y Iris Chen
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Neurosci Lett 444:117-21. 2008
  10. pmc Inhibition of stimulated dopamine release and hemodynamic response in the brain through electrical stimulation of rat forepaw
    Y Iris Chen
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Room 2301, Charlestown, MA 02129, USA
    Neurosci Lett 431:231-5. 2008

Detail Information

Publications26

  1. pmc Record of a single fMRI experiment in May of 1991
    Kenneth K Kwong
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA
    Neuroimage 62:610-2. 2012
    ..Thomas Brady and Dr. Bruce Rosen at the MGH-NMR Center provided the indispensable support for highly risky ideas to roam and succeed. The paper offers a first person account of the steps that led to the May experiment and its aftermath...
  2. pmc Early time points perfusion imaging
    Kenneth K Kwong
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 54:1070-82. 2011
    ..A recipe to run ET was presented, with attention paid to the noise problem around the time of arrival (TOA) of the contrast agent...
  3. pmc Early time points perfusion imaging: theoretical analysis of correction factors for relative cerebral blood flow estimation given local arterial input function
    Kenneth K Kwong
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 57:182-9. 2011
    ..In the specific case of using normalized gamma-variate function as a model for AIF, the correction factor for C(t) (but not for MD1) at the time to reach the maximum derivative is relatively insensitive to the shape of the local AIF...
  4. pmc Early time points perfusion imaging: relative time of arrival, maximum derivatives and fractional derivatives
    Kenneth K Kwong
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 57:979-90. 2011
    ..5 to 2, estimated rCBF results were found to demonstrate a gray-white matter ratio of approximately 3, a number consistent with flow ratio reported in the literature...
  5. pmc Acupuncture mobilizes the brain's default mode and its anti-correlated network in healthy subjects
    Kathleen K S Hui
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129, USA
    Brain Res 1287:84-103. 2009
    ..Our results suggest that acupuncture mobilizes the anti-correlated functional networks of the brain to mediate its actions, and that the effect is dependent on the psychophysical response...
  6. pmc Acupuncture, the limbic system, and the anticorrelated networks of the brain
    Kathleen K S Hui
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA
    Auton Neurosci 157:81-90. 2010
    ....
  7. pmc Time-variant fMRI activity in the brainstem and higher structures in response to acupuncture
    Vitaly Napadow
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 47:289-301. 2009
    ..Our protocol also demonstrates a fMRI approach to study habituation and other time-variant phenomena over longer time durations...
  8. ncbi request reprint Somatosensory cortical plasticity in carpal tunnel syndrome treated by acupuncture
    Vitaly Napadow
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Hum Brain Mapp 28:159-71. 2007
    ..Acupuncture, a somatosensory conditioning stimulus, shows promise in inducing beneficial cortical plasticity manifested by more focused digital representations...
  9. pmc Electrical stimulation modulates the amphetamine-induced hemodynamic changes: an fMRI study to compare the effect of stimulating locations and frequencies on rats
    Y Iris Chen
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Neurosci Lett 444:117-21. 2008
    ..This therefore provided insight into the neurophysiological basis of electroacupuncture effects in cortical and subcortical circuits...
  10. pmc Inhibition of stimulated dopamine release and hemodynamic response in the brain through electrical stimulation of rat forepaw
    Y Iris Chen
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Room 2301, Charlestown, MA 02129, USA
    Neurosci Lett 431:231-5. 2008
    ..These data provide evidence for physiologic modulation caused by electroacupuncture at points near the median nerve...
  11. pmc Commonality and specificity of acupuncture action at three acupoints as evidenced by FMRI
    Joshua D Claunch
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, USA
    Am J Chin Med 40:695-712. 2012
    ..Our findings showing preferential response of certain limbic-paralimbic structures suggests acupoints may also exhibit relative specificity...
  12. doi request reprint Does guasha offer hepatoprotective effect to chronic inactive hepatitis B carriers? A built-in design to control subject expectation
    Suk Tak Chan
    1 Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA
    J Altern Complement Med 19:772-6. 2013
    ..The purpose of this case study was to investigate whether hepatoprotective biochemical markers previously measured in active-CHB in response to Guasha were also present in controls...
  13. ncbi request reprint Somatosensory cortical plasticity in carpal tunnel syndrome--a cross-sectional fMRI evaluation
    Vitaly Napadow
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA
    Neuroimage 31:520-30. 2006
    ..Our results are consistent with Hebbian plasticity mechanisms, as our cohort of CTS patients had predominant paresthesias, which produce more temporally coherent afferent signaling from affected digits...
  14. pmc Restoring cerebral dopamine homeostasis by electrical forepaw stimulation: an FMRI study
    Y Iris Chen
    Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Synapse 66:331-9. 2012
    ..This study shows not only the capacity of peripheral stimulation to perturb neurotransmitter function, but also the potential of peripheral stimulation to restore neurotransmitter homeostasis...
  15. ncbi request reprint The role of the basal ganglia in bimanual coordination
    Eduard Kraft
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
    Brain Res 1151:62-73. 2007
    ..Our results suggest a critical role of the basal ganglia in the neural control of bimanual coordination...
  16. ncbi request reprint Effects of electroacupuncture versus manual acupuncture on the human brain as measured by fMRI
    Vitaly Napadow
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Hum Brain Mapp 24:193-205. 2005
    ....
  17. ncbi request reprint Functional imaging of working memory in obstructive sleep-disordered breathing
    Robert J Thomas
    Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, CC 866, Sleep Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Appl Physiol (1985) 98:2226-34. 2005
    ..There may be dissociations between respiratory vs. cortical recovery and objective vs. subjective recovery. Hypofrontality may provide a plausible biological mechanism for a clinical overlap with disorders of mood and attention...
  18. pmc Functional MRI using regularized parallel imaging acquisition
    Fa Hsuan Lin
    Massachusetts General Hospital, Department of Radiology, MGH HMS MIT, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA
    Magn Reson Med 54:343-53. 2005
    ..Human motor and visual fMRI data acquired at different field strengths and array coils also demonstrate that regularized SENSE improves the detection of functionally active brain regions...
  19. ncbi request reprint Strategies for improving the detection of fMRI activation in trigeminal pathways with cardiac gating
    Wei Ting Zhang
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, and Harvard Medical School, Bldg 149 2301, 13th Street, Charlestown, MA 02129, USA
    Neuroimage 31:1506-12. 2006
    ..Activation in the brainstem and the thalamus was best detected by cardiac-gated dual-echo EPI...
  20. pmc Dynamic functional cerebral blood volume responses to normobaric hyperoxia in acute ischemic stroke
    Ona Wu
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Cereb Blood Flow Metab 32:1800-9. 2012
    ..In addition, CBV responses to NBO challenge may have potential as an imaging marker to distinguish ischemic core from salvageable tissues...
  21. doi request reprint Measurement of human brown adipose tissue volume and activity using anatomic MR imaging and functional MR imaging
    YIN CHING IRIS CHEN
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Nucl Med 54:1584-7. 2013
    ..The aim of this study was to assess the volume and function of human brown adipose tissue (BAT) in vivo using MR imaging...
  22. doi request reprint Anatomical and functional assessment of brown adipose tissue by magnetic resonance imaging
    Y Iris Chen
    A Martino s Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA
    Obesity (Silver Spring) 20:1519-26. 2012
    ..In conclusion, we demonstrate the feasibility of measuring BAT volume and function in vivo using routine MRI sequences. The MRI measurement of BAT volume is consistent with quantitative measurement of the tissue ex vivo...
  23. ncbi request reprint Dynamic magnetic resonance inverse imaging of human brain function
    Fa Hsuan Lin
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Magn Reson Med 56:787-802. 2006
    ..InI is expected to improve the time resolution of MRI and provide increased flexibility in the trade-off between spatial and temporal resolution for studies of dynamic activation patterns in the human brain...
  24. ncbi request reprint Using fMRI to dissociate sensory encoding from cognitive evaluation of heat pain intensity
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Hum Brain Mapp 27:715-21. 2006
    ..We hypothesize that these two regions play a crucial role in bridging the encoding of pain sensation and the cognitive processing of sensory input...
  25. ncbi request reprint The integrated response of the human cerebro-cerebellar and limbic systems to acupuncture stimulation at ST 36 as evidenced by fMRI
    Kathleen K S Hui
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Room 2301, Charlestown, MA 02129, USA
    Neuroimage 27:479-96. 2005
    ..The study provides preliminary evidence for an integrated response of the human cerebro-cerebellar and limbic systems to acupuncture stimulation at ST 36 that correlates with the psychophysical response...
  26. doi request reprint Guasha-induced hepatoprotection in chronic active hepatitis B: a case study
    Suk Tak Chan
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, MA 02129, United States
    Clin Chim Acta 412:1686-8. 2011
    ..HO-1 was also reported to be upregulated with Guasha, an ancient therapeutic technique which applies instrument assisted press-stroking to treat many disorders...