Dora Kovacs

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit
    Manuel T Gersbacher
    Neurobiology of Disease Laboratory, Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Mol Neurodegener 5:61. 2010

Research Grants

  1. PS1 and BACE1 regulate processing and activity of voltage-gated sodium channels
    Dora M Kovacs; Fiscal Year: 2010
  2. ACAT inhibition regulates ERAD of APP and Abeta production
    Dora Kovacs; Fiscal Year: 2007
  3. Role of the g-secretase/PS1 complex in APP processing
    Dora Kovacs; Fiscal Year: 2007
  4. Cholesterol distribution & regulation of AB generation
    Dora Kovacs; Fiscal Year: 2006
  5. Role of the g-secretase/PS1 complex in APP processing
    Dora Kovacs; Fiscal Year: 2006
  6. ACAT inhibition regulates ERAD of APP and Abeta production
    Dora M Kovacs; Fiscal Year: 2010

Collaborators

  • Manuel T Gersbacher
  • Raja Bhattacharyya
  • Doo Yeon Kim

Detail Information

Publications1

  1. ncbi Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit
    Manuel T Gersbacher
    Neurobiology of Disease Laboratory, Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Mol Neurodegener 5:61. 2010
    ..abstract:..

Research Grants15

  1. PS1 and BACE1 regulate processing and activity of voltage-gated sodium channels
    Dora M Kovacs; Fiscal Year: 2010
    ..Moreover, our preliminary data suggest that BACE1 and/or y-secretase inhibitors could affect VGSC function, and be beneficial in normalizing membrane excitability in AD patients with elevated BACE1 activity. ..
  2. ACAT inhibition regulates ERAD of APP and Abeta production
    Dora Kovacs; Fiscal Year: 2007
    ..These studies should further elucidate the prospects for employing ACAT inhibition as a novel therapeutic for AD. ..
  3. Role of the g-secretase/PS1 complex in APP processing
    Dora Kovacs; Fiscal Year: 2007
    ..RESEARCH GRANT TABLE OF CONTENTS Page Numbe_ Face Page ....................................................................................................... Description, ..
  4. Cholesterol distribution & regulation of AB generation
    Dora Kovacs; Fiscal Year: 2006
    ..These studies should provide a clearer understanding of the molecular and biochemicalevents involved in cholesterol-dependent regulation of Ab generation. ..
  5. Role of the g-secretase/PS1 complex in APP processing
    Dora Kovacs; Fiscal Year: 2006
    ..abstract_text> ..
  6. ACAT inhibition regulates ERAD of APP and Abeta production
    Dora M Kovacs; Fiscal Year: 2010
    ..These studies should further elucidate the prospects for employing ACAT inhibition as a novel therapeutic for AD. ..