Research Topics
Genomes and GenesSpecies | Joanne KotsopoulosSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancerJoanne Kotsopoulos
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
Cancer Causes Control 20:335-44. 2009..Furthermore, we did not observe any clear gene-environment interactions between caffeine metabolizing genes and ovarian cancer. Future studies evaluating mechanisms by which coffee mediates this relationship are warranted...
Reproducibility of plasma and urine biomarkers among premenopausal and postmenopausal women from the Nurses' Health StudiesJoanne Kotsopoulos
Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 19:938-46. 2010..Temporal variability of biomarkers should be evaluated before their use in epidemiologic studies...
Anthropometric measures and risk of epithelial ovarian cancer: results from the nurses' health studyJoanne Kotsopoulos
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Obesity (Silver Spring) 18:1625-31. 2010..The differential effect of hip circumference based on menopausal status requires further confirmation...
Dietary betaine and choline intake are not associated with risk of epithelial ovarian cancerJ Kotsopoulos
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Eur J Clin Nutr 64:111-4. 2010..These data provide little evidence for a role of these nutrients in ovarian cancer etiology...
Relationship between dietary and supplemental intake of folate, methionine, vitamin B6 and folate receptor alpha expression in ovarian tumorsJoanne Kotsopoulos
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Int J Cancer 126:2191-8. 2010..Our data do not support the hypothesis that the relationship between factors involved in one-carbon metabolism and ovarian cancer risk differs by FRalpha status of the tumor...
+331G/A variant in the progesterone receptor gene, postmenopausal hormone use and risk of breast cancerJoanne Kotsopoulos
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Int J Cancer 125:1685-91. 2009..This finding adds to the evidence that the PR has an important etiologic role in breast cancer and should be evaluated in future studies...
Relationship between caffeine intake and plasma sex hormone concentrations in premenopausal and postmenopausal womenJoanne Kotsopoulos
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Cancer 115:2765-74. 2009..Caffeine intake may decrease risk of breast and ovarian cancer, although the data are not entirely consistent. Whether or not caffeine affects cancer risk by altering sex hormone levels is currently unknown...
Risk factors for ductal and lobular breast cancer: results from the nurses' health studyJoanne Kotsopoulos
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Breast Cancer Res 12:R106. 2010....
Duarte galactose-1-phosphate uridyl transferase genotypes are not associated with ovarian cancer riskMelissa A Merritt
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Fertil Steril 98:687-91. 2012..To investigate whether galactose-1-phosphate uridyl transferase (GALT) variant genotypes were associated with epithelial ovarian cancer risk, and to determine if this association was modified by lactose intake...
Validation of tissue microarray technology in ovarian cancer: results from the Nurses' Health StudyJonathan L Hecht
Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
Cancer Epidemiol Biomarkers Prev 17:3043-50. 2008..Tissue microarrays (TMAs) allow high-throughput evaluation of protein expression from archived tissue samples. We identified characteristics specific to ovarian cancer that may influence TMA interpretation...
Relationship between epidemiologic risk factors and hormone receptor expression in ovarian cancer: results from the Nurses' Health StudyJonathan L Hecht
Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA
Cancer Epidemiol Biomarkers Prev 18:1624-30. 2009..Reproductive and hormonal risk factors are associated with subgroups of ovarian cancer defined by histologic subtype or ERalpha and PR status. These finding support specific models of hormone mediated triggers of ovarian cancer...
