Detail Information
Publications
Thin PDMS films using long spin times or tert-butyl alcohol as a solventJohn H Koschwanez
Department of Electrical Engineering, University of Washington, Seattle, Washington, United States of America
PLoS ONE 4:e4572. 2009..The use of tert-butyl alcohol to spin thin PDMS films does not swell the underlying PDMS substrate, and we have used these films to construct multilayer PDMS devices...
Sucrose utilization in budding yeast as a model for the origin of undifferentiated multicellularityJohn H Koschwanez
FAS Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America
PLoS Biol 9:e1001122. 2011..We propose that the prior use of public goods led to selection for the incomplete cell separation that first produced multicellularity...
Easily fabricated magnetic traps for single-cell applicationsJohn H Koschwanez
Department of Electrical Engineering, University of Washington, Seattle, WA 98195 2500, USA
Rev Sci Instrum 78:044301. 2007..We demonstrate individual yeast cell capture and estimate the capture force (1.9-4.4 pN) by measuring the flow speed required to remove the cell from its trap in a microfluidic channel...
Improved use of a public good selects for the evolution of undifferentiated multicellularityJohn H Koschwanez
FAS Center for Systems Biology and Department of Molecular and Cellular Biology, Harvard University, Cambridge, United States
elife 2:e00367. 2013..Our study shows that combining rational design with experimental evolution can help evaluate hypotheses about evolutionary strategies. DOI:http://dx.doi.org/10.7554/eLife.00367.001...
