Karestan Koenen

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Posttraumatic stress disorder and late-onset smoking in the Vietnam era twin registry
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, and The Miriam Hospital, Providence, RI, USA
    J Consult Clin Psychol 74:186-90. 2006
  2. pmc The posttraumatic stress disorder project in Brazil: neuropsychological, structural and molecular neuroimaging studies in victims of urban violence
    Rodrigo A Bressan
    Laboratório Interdisciplinar de Neurosciencias Clínicas LiNC, Sao Paulo, Brazil
    BMC Psychiatry 9:30. 2009
  3. pmc RGS2 and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults
    Karestan C Koenen
    Department of Society, Human Development and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Depress Anxiety 26:309-15. 2009
  4. pmc Genetic influences on the overlap between low IQ and antisocial behavior in young children
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    J Abnorm Psychol 115:787-97. 2006
  5. ncbi request reprint Women's status and child well-being: a state-level analysis
    Karestan C Koenen
    Harvard School of Public Health Boston, MA, USA
    Soc Sci Med 63:2999-3012. 2006
  6. pmc Early childhood factors associated with the development of post-traumatic stress disorder: results from a longitudinal birth cohort
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Psychol Med 37:181-92. 2007
  7. pmc Modification of the association between serotonin transporter genotype and risk of posttraumatic stress disorder in adults by county-level social environment
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 169:704-11. 2009
  8. pmc Common genetic liability to major depression and posttraumatic stress disorder in men
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, United States
    J Affect Disord 105:109-15. 2008
  9. pmc Pervasive trauma exposure among US sexual orientation minority adults and risk of posttraumatic stress disorder
    Andrea L Roberts
    Department of Society, Human Development, and Health, School of Public Health, Harvard University, Boston, MA 02115, USA
    Am J Public Health 100:2433-41. 2010
  10. pmc A prospective study of sex differences in the lifetime risk of posttraumatic stress disorder among abused and neglected children grown up
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    J Trauma Stress 22:566-74. 2009

Research Grants

  1. Genetic Determinants of PTSD in Women
    Karestan C Koenen; Fiscal Year: 2010
  2. Development Epidemiology of PTSD
    Karestan Koenen; Fiscal Year: 2007
  3. Genetic Determinants of PTSD in Women
    Karestan Koenen; Fiscal Year: 2007
  4. Genetic Determinants of PTSD in Women
    Karestan Koenen; Fiscal Year: 2009

Detail Information

Publications72

  1. ncbi request reprint Posttraumatic stress disorder and late-onset smoking in the Vietnam era twin registry
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, and The Miriam Hospital, Providence, RI, USA
    J Consult Clin Psychol 74:186-90. 2006
    ..If replicated, these results identify PTSD as a risk factor for smoking that should lead to early tobacco control treatment in this population...
  2. pmc The posttraumatic stress disorder project in Brazil: neuropsychological, structural and molecular neuroimaging studies in victims of urban violence
    Rodrigo A Bressan
    Laboratório Interdisciplinar de Neurosciencias Clínicas LiNC, Sao Paulo, Brazil
    BMC Psychiatry 9:30. 2009
    ..This paper shows the research rationale and design for these three case-control studies...
  3. pmc RGS2 and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults
    Karestan C Koenen
    Department of Society, Human Development and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Depress Anxiety 26:309-15. 2009
    ..We examined whether rs4606, a single nucleotide polymorphism (SNP) in the 3' UTR of RGS2, was associated with GAD in an epidemiologic sample of adults exposed to the 2004 Florida Hurricanes...
  4. pmc Genetic influences on the overlap between low IQ and antisocial behavior in young children
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    J Abnorm Psychol 115:787-97. 2006
    ..Genetic influences common to both phenotypes explained 100% of the low IQ-antisocial behavior relation in boys. Findings suggest that specific candidate genes and neurobiological processes should be tested in relation to both phenotypes...
  5. ncbi request reprint Women's status and child well-being: a state-level analysis
    Karestan C Koenen
    Harvard School of Public Health Boston, MA, USA
    Soc Sci Med 63:2999-3012. 2006
    ..Women's status is an important aspect of children's social context which may impact their well-being. Multi-level analyses of the association between state-level women's status and child well-being are needed...
  6. pmc Early childhood factors associated with the development of post-traumatic stress disorder: results from a longitudinal birth cohort
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Psychol Med 37:181-92. 2007
    ..We examined the association between childhood neurodevelopmental, temperamental, behavioral and family environmental characteristics assessed before age 11 years and the development of PTSD up to age 32 years in a birth cohort...
  7. pmc Modification of the association between serotonin transporter genotype and risk of posttraumatic stress disorder in adults by county-level social environment
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 169:704-11. 2009
    ..These results suggest that social environment modifies the effect of 5-HTTLPR genotype on PTSD risk...
  8. pmc Common genetic liability to major depression and posttraumatic stress disorder in men
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, United States
    J Affect Disord 105:109-15. 2008
    ..The degree to which a common genetic liability explains the etiology of the MD-PTSD association has not been quantified and has important implications for research and prevention...
  9. pmc Pervasive trauma exposure among US sexual orientation minority adults and risk of posttraumatic stress disorder
    Andrea L Roberts
    Department of Society, Human Development, and Health, School of Public Health, Harvard University, Boston, MA 02115, USA
    Am J Public Health 100:2433-41. 2010
    ..We assessed sexual orientation disparities in exposure to violence and other potentially traumatic events and onset of posttraumatic stress disorder (PTSD) in a representative US sample...
  10. pmc A prospective study of sex differences in the lifetime risk of posttraumatic stress disorder among abused and neglected children grown up
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    J Trauma Stress 22:566-74. 2009
    ..Future research should identify mechanisms that make female victims particularly vulnerable to revictimization and the development of PTSD...
  11. ncbi request reprint Genetics of posttraumatic stress disorder: Review and recommendations for future studies
    Karestan C Koenen
    Department of Society, Human Development, and Health and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Trauma Stress 20:737-50. 2007
    ..Recommendations for future studies are presented with emphasis on study design and assessment issues particular to the field of trauma and PTSD. Clinical implications of PTSD genetic studies are discussed...
  12. pmc Gene-environment interaction in posttraumatic stress disorder: an update
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    J Trauma Stress 22:416-26. 2009
    ..The authors posit that GxE research is vital to elucidating risk and resilience following exposure to a potentially traumatic event...
  13. pmc Gene-environment interaction in posttraumatic stress disorder: review, strategy and new directions for future research
    Karestan C Koenen
    Department of Society, Human Development, and Health and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Eur Arch Psychiatry Clin Neurosci 258:82-96. 2008
    ..Finally, we propose some promising new directions for PTSD G x E research. We suggest that G x E research in PTSD is essential to understanding vulnerability and resilience following exposure to a traumatic event...
  14. pmc Protocol for investigating genetic determinants of posttraumatic stress disorder in women from the Nurses' Health Study II
    Karestan C Koenen
    Department of Society, Human Development and Health, Harvard School of Public Health, Boston, MA 02115, USA
    BMC Psychiatry 9:29. 2009
    ..Although twin studies suggest genetic influences account for substantial variance in PTSD risk, little progress has been made in identifying variants in specific genes that influence liability to this common, debilitating disorder...
  15. pmc Childhood IQ and adult mental disorders: a test of the cognitive reserve hypothesis
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Kresge 613, 677 Huntington Ave, Boston, MA 02115, USA
    Am J Psychiatry 166:50-7. 2009
    ..The authors tested the hypothesis that low childhood IQ is associated with increased risk and severity of adult mental disorders...
  16. pmc The developmental mental-disorder histories of adults with posttraumatic stress disorder: a prospective longitudinal birth cohort study
    Karestan C Koenen
    Department of Society Human Development and Health, Harvard School of Public Health, Boston, MA 02115, USA
    J Abnorm Psychol 117:460-6. 2008
    ..Juvenile mental-disorder histories may help indicate which individuals are most likely to develop PTSD in populations at high risk of trauma exposure...
  17. pmc SLC6A4 methylation modifies the effect of the number of traumatic events on risk for posttraumatic stress disorder
    Karestan C Koenen
    Departments of Society, Human Development, and Health and Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Depress Anxiety 28:639-47. 2011
    ....
  18. ncbi request reprint Juvenile conduct disorder as a risk factor for trauma exposure and posttraumatic stress disorder
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Trauma Stress 18:23-32. 2005
    ..The findings suggest CD increases risk for trauma exposure and PTSD among male veterans through direct and indirect mechanisms. Veterans who have a history of CD are at high risk for trauma exposure and development of PTSD...
  19. ncbi request reprint Developmental epidemiology of PTSD: self-regulation as a central mechanism
    Karestan C Koenen
    Harvard School of Public Health, Department of Society, Human Development and Health, 677 Huntington Avenue, Kresge 613, Boston, MA 02115, USA
    Ann N Y Acad Sci 1071:255-66. 2006
    ..The implications of a developmentally informed epidemiologic approach to PTSD for theory, research, and practice are discussed...
  20. ncbi request reprint A twin registry study of the relationship between posttraumatic stress disorder and nicotine dependence in men
    Karestan C Koenen
    Department of Society, Human Development, and Health, Harvard School of Public Health, 677 Huntington Avenue, Kresge 613, Boston, MA 02115, USA
    Arch Gen Psychiatry 62:1258-65. 2005
    ..Recent studies indicate a strong association between posttraumatic stress disorder (PTSD) and nicotine dependence (ND). However, the explanation for the association remains unclear...
  21. pmc Nature-nurture interplay: genetically informative designs contribute to understanding the effects of trauma and interpersonal violence
    Karestan C Koenen
    Harvard School of Public Health, Department of Society, Human Development, and Health, Boston, MA 02115, USA
    J Interpers Violence 20:507-12. 2005
    ..This report briefly discusses the gains made from this research approach and the promising future for genetically informative trauma and violence research...
  22. pmc Relation between clinical depression risk and physical activity and time spent watching television in older women: a 10-year prospective follow-up study
    Michel Lucas
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 174:1017-27. 2011
    ..13 (95% confidence interval: 1.00, 1.27; P(trend) = 0.01). Analyses simultaneously considering PA and television watching suggested that both contributed independently to depression risk...
  23. pmc Coffee, caffeine, and risk of depression among women
    Michel Lucas
    Department of Nutrition, Harvard School of Public Health, and Department of Medicine, Brigham and Women s Hospital, 655 Huntington Ave, Boston, MA 02115, USA
    Arch Intern Med 171:1571-8. 2011
    ..However, studies that analyze prospectively the relationship between coffee or caffeine consumption and depression risk are scarce...
  24. pmc Posttraumatic stress disorder and the genetic structure of comorbidity
    Erika J Wolf
    National Center for PTSD, VA Boston Healthcare System and Department of Psychology, Boston University, Boston, MA, USA
    J Abnorm Psychol 119:320-30. 2010
    ..Shared genetic variance across the 2 dimensions explained 67% of their phenotypic correlation (r = .52). These findings have implications for conceptualizations of the etiology of PTSD and its location in an empirically based nosology...
  25. pmc Racial discrimination, psychological distress, and self-rated health among US-born and foreign-born Black Americans
    Nancy Krieger
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Public Health 101:1704-13. 2011
    ..We investigated associations among racial discrimination, psychological distress, and self-rated health among US-born and immigrant Black Americans...
  26. ncbi request reprint Spiritual well-being and health
    Ming T Tsuang
    Department of Psychiatry, Center for Behavioral Genomics, University of California, San Diego 92037, and Massachusetts General Hospital, Boston, Massachusetts, USA
    J Nerv Ment Dis 195:673-80. 2007
    ..We concluded that studies of SWB and health should continue to distinguish between explicitly religious variables and others that more closely approximate the psychological construct of personal well-being...
  27. doi request reprint Occupational, social, and relationship hazards and psychological distress among low-income workers: implications of the 'inverse hazard law'
    Nancy Krieger
    Department of Society, Human Development, and Health, Harvard School of Public Health, 677 Huntington Avenue, Kresge 717, Boston, MA 02115, USA
    J Epidemiol Community Health 65:260-72. 2011
    ....
  28. ncbi request reprint Risk factors for partner violence among a national sample of combat veterans
    Casey T Taft
    National Center for Posttraumatic Stress Disorder, Veterans Affairs Boston Healthcare System, Boston, MA 02130, USA
    J Consult Clin Psychol 73:151-9. 2005
    ....
  29. ncbi request reprint A twin study of sexual behavior in men
    Michael J Lyons
    Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    Arch Sex Behav 33:129-36. 2004
    ..The data suggest that the observed association between age of initiation of sexual relations and having multiple partners is due to genetic influences common to both behaviors...
  30. pmc Cumulative stress and maternal prenatal corticotropin-releasing hormone in an urban U.S. cohort
    Alison C Tse
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Psychoneuroendocrinology 37:970-9. 2012
    ..To date, there have been conflicting reports of the association of psychosocial stressors with prenatal corticotropin-releasing hormone (CRH) levels...
  31. pmc A prospective study of posttraumatic stress disorder symptoms and coronary heart disease in women
    Laura D Kubzansky
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Health Psychol 28:125-30. 2009
    ..No study has tested this hypothesis in women even though PTSD is more prevalent among women than men. This study aims to examine whether higher levels of PTSD symptoms are associated with increased risk of incident CHD among women...
  32. pmc Maternal depressive symptoms not associated with reduced height in young children in a US prospective cohort study
    Karen A Ertel
    Department of Society, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 5:e13656. 2010
    ..We examined the relationships between antenatal and postpartum depressive symptoms and child height and linear growth from birth to age 3 years in a U.S. sample...
  33. pmc Is posttraumatic stress disorder related to development of heart disease? An update
    Laura D Kubzansky
    Department of Soci ety, Human Development and Health, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cleve Clin J Med 76:S60-5. 2009
    ..A better understanding of the relationship will increase prevention and intervention efforts. Cardiologists may be most effective when they can recognize and manage emotional distress in practice...
  34. ncbi request reprint Co-twin control study of relationships among combat exposure, combat-related PTSD, and other mental disorders
    Karestan C Koenen
    Women s Health Sciences Division, National Center for PTSD, VA Boston Healthcare System, Boston, Massachusetts 02114, USA
    J Trauma Stress 16:433-8. 2003
    ..We conclude C-PTSD comorbidity persists after controlling for shared vulnerability. Combat exposure is directly and indirectly, through C-PTSD, associated with increased risk for other mental disorders...
  35. doi request reprint A longitudinal study of maternal depression and child maltreatment in a national sample of families investigated by child protective services
    Kerith J Conron
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 163:922-30. 2009
    ..To assess whether a change in depression predicts a mother's change in maltreatment...
  36. pmc Witness of intimate partner violence in childhood and perpetration of intimate partner violence in adulthood
    Andrea L Roberts
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 21:809-18. 2010
    ..Witnessing such violence in childhood has been proposed as a principal cause of adulthood perpetration, yet it remains unknown whether the association between witnessing intimate partner violence and adulthood perpetration is causal...
  37. ncbi request reprint Prospective study of posttraumatic stress disorder symptoms and coronary heart disease in the Normative Aging Study
    Laura D Kubzansky
    Harvard School of Public Health, Veterans Affairs Normative Aging Study, Veterans Affairs Boston Health Care System, Boston University School of Medicine, 677 Huntington Avenue, Boston, MA 02115, USA
    Arch Gen Psychiatry 64:109-16. 2007
    ..To our knowledge, no prospective studies to date have evaluated whether PTSD is associated with increased risk of CHD...
  38. doi request reprint Antenatal and postpartum depressive symptoms are differentially associated with early childhood weight and adiposity
    Karen A Ertel
    Departments of Society, Human Development, and Health, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Paediatr Perinat Epidemiol 24:179-89. 2010
    ..14 [0.11, 2.18]). In conclusion, whereas antenatal depression was associated with smaller size and central adiposity at age 3 years, postpartum depression was associated with higher overall adiposity...
  39. pmc Social factors, psychopathology, and maternal smoking during pregnancy
    Stephen E Gilman
    Department of Society, Human Development, and Health, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    Am J Public Health 98:448-53. 2008
    ..5%), compared with women with a college degree and without nicotine dependence (3.9%). More effective and accessible interventions for nicotine dependence among pregnant smokers are needed...
  40. pmc Persisting posttraumatic stress disorder symptoms and their relationship to functioning in Vietnam veterans: a 14-year follow-up
    Karestan C Koenen
    Departments of Society, Human Development, and Health and Epidemiology, Harvard School of Public Health, Boston, MA, USA
    J Trauma Stress 21:49-57. 2008
    ..Further investigation is needed to determine whether the PTSD-functioning relationship is causal and if successful treatment of PTSD is associated with improvement in functioning...
  41. pmc Childhood social environment, emotional reactivity to stress, and mood and anxiety disorders across the life course
    Katie A McLaughlin
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Depress Anxiety 27:1087-94. 2010
    ..We investigate whether emotional reactivity to stress is a mechanism in the association between childhood environment characteristics and adult mood and anxiety disorders...
  42. pmc Emotional functioning at age 7 years is associated with C-reactive protein in middle adulthood
    Allison A Appleton
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    Psychosom Med 73:295-303. 2011
    ..Therefore, we evaluated whether child emotional functioning at age 7 years is associated with C-reactive protein (CRP), an indicator of systemic inflammation, in middle adulthood...
  43. pmc Incorporating home demands into models of job strain: findings from the work, family, and health network
    Karen A Ertel
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston MA 02115, USA
    J Occup Environ Med 50:1244-52. 2008
    ..The purpose of this article was to integrate home demands with the demand-control-support model to test if home demands interact with job strain to increase depressive symptoms...
  44. pmc Stability of autistic traits in the general population: further evidence for a continuum of impairment
    Elise B Robinson
    Harvard School of Public Health, Boston, MA, USA
    J Am Acad Child Adolesc Psychiatry 50:376-84. 2011
    ..This study investigated the developmental course of autistic traits in a nationally representative sample of subjects 7 to 13 years of age...
  45. pmc Adulthood stressors, history of childhood adversity, and risk of perpetration of intimate partner violence
    Andrea L Roberts
    Department of Society, Human Development and Health, Harvard School of Public Health, Boston, MA, USA
    Am J Prev Med 40:128-38. 2011
    ..women and more than 100,000 men are treated for injuries from intimate partner violence (IPV) annually, making IPV perpetration a major public health problem. However, little is known about causes of perpetration across the life course...
  46. pmc Childhood sexual abuse is highly associated with HIV risk-taking behavior and infection among MSM in the EXPLORE Study
    Matthew J Mimiaga
    Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
    J Acquir Immune Defic Syndr 51:340-8. 2009
    ....
  47. pmc Performance of polygenic scores for predicting phobic anxiety
    Stefan Walter
    Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston, Massachusetts, United States of America Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 8:e80326. 2013
    ..S., and are responsible for substantial burdens of disability, missed work days and health care utilization. To date, no causal genetic variants have been identified for anxiety, anxiety disorders, or related traits...
  48. doi request reprint Experiences and sexual behaviors of HIV-infected MSM who acquired HIV in the context of crystal methamphetamine use
    Matthew J Mimiaga
    Fenway Institute, Fenway Community Health, Boston, MA 02119, USA
    AIDS Educ Prev 20:30-41. 2008
    ..The study also draws attention to the need for associated mental health, functional and quality-of life impairments that seem to accompany continued use in individuals with HIV...
  49. ncbi request reprint Environmental mediation and the twin design
    Shaun Purcell
    Psychiatry and Neurodevelopmental Genetics Unit, Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, USA
    Behav Genet 35:491-8. 2005
    ..Based on a simple simulation study, recommendations are given as to which methods should be applied and which should be avoided...
  50. pmc Dietary intake of n-3 and n-6 fatty acids and the risk of clinical depression in women: a 10-y prospective follow-up study
    Michel Lucas
    Departments of Nutrition and Society, Human Development, and Health, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 93:1337-43. 2011
    ..The associations between different sources of dietary n-3 (omega-3) and n-6 (omega-6) fatty acids and the risk of depression have not been prospectively studied...
  51. ncbi request reprint Separation anxiety as a mediator between acute morphine administration and PTSD symptoms in injured children
    Glenn Saxe
    Department of Child and Adolescent Psychiatry, Dowling 1 North One Boston Medical Center Place, Boston, MA 02118 2393, USA
    Ann N Y Acad Sci 1071:41-5. 2006
    ..These findings have implications for our understanding of morphine's effects on psychological functioning following an acute injury and for direct clinical care...
  52. ncbi request reprint Intimate partner psychological aggression and child behavior problems
    Stephanie B Clarke
    Women s Health Sciences Division, National Center for PTSD, VA Boston Healthcare System, Boston, MA, USA
    J Trauma Stress 20:97-101. 2007
    ..The association between psychological aggression and child behavior problems was partially mediated by maternal distress. Exposure to psychological aggression appears to have unique direct and indirect adverse effects on children...
  53. pmc Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies
    Marilyn C Cornelis
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Curr Psychiatry Rep 12:313-26. 2010
    ..Genome-wide association studies offer the best opportunity to identify novel "true" risk variants for the disorder that in turn has the potential to inform our understanding of PTSD etiology...
  54. ncbi request reprint Domestic violence is associated with environmental suppression of IQ in young children
    Karestan C Koenen
    National Child Traumatic Stress Network, Department of Child and Adolescent Psychiatry, Boston University Medical Center, MA 02118, USA
    Dev Psychopathol 15:297-311. 2003
    ....
  55. ncbi request reprint A high risk twin study of combat-related PTSD comorbidity
    Karestan C Koenen
    Women s Health Sciences Division 116B 3, National Center for PTSD, VA Boston Healthcare System, MA 02130, USA
    Twin Res 6:218-26. 2003
    ....
  56. ncbi request reprint Posttraumatic stress disorder and treatment seeking in a national screening sample
    Karestan C Koenen
    Division of Epidemiology, The Joseph L Mailman School of Public Health, Columbia University, New York, USA
    J Trauma Stress 16:5-16. 2003
    ....
  57. ncbi request reprint Skills training in affective and interpersonal regulation followed by exposure: a phase-based treatment for PTSD related to childhood abuse
    Marylene Cloitre
    New York Presbyterian Hospital Weill Medical College of Cornell University, New York, USA
    J Consult Clin Psychol 70:1067-74. 2002
    ....
  58. ncbi request reprint Positive tertiary appraisals and posttraumatic stress disorder in U.S. male veterans of the war in Vietnam: the roles of positive affirmation, positive reformulation, and defensive denial
    Bruce P Dohrenwend
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    J Consult Clin Psychol 72:417-33. 2004
    ..The possibility that mainly positive tertiary appraisals also contribute to successful postwar adaptation is discussed...
  59. ncbi request reprint Incidence of and risk factors for acute stress disorder in children with injuries
    Glenn N Saxe
    Department of Child and Adolescent Psychiatry, Boston Medical Center, MA 02118, USA
    J Trauma 59:946-53. 2005
    ..Numerous studies have documented the increased incidence of PTSD in those initially diagnosed with ASD. PTSD symptoms cause tremendous morbidity and may persist for many years in some children...
  60. ncbi request reprint Risk factors for course of posttraumatic stress disorder among Vietnam veterans: a 14-year follow-up of American Legionnaires
    Karestan C Koenen
    Women s Health Sciences Division, National Center for Posttraumatic Stress Disorder, VA Boston Healthcare System, USA
    J Consult Clin Psychol 71:980-6. 2003
    ..Combat exposure predicted PTSD course more strongly than any other risk factor. Findings suggest recovery from PTSD is significantly influenced by perceived social support...
  61. ncbi request reprint A twin registry study of familial and individual risk factors for trauma exposure and posttraumatic stress disorder
    Karestan C Koenen
    Division of Epidemiology, Mailman School of Public Health, Columbia University, PH 18 EPI, 600 West 168th Street, New York, New York 10032, USA
    J Nerv Ment Dis 190:209-18. 2002
    ..Results suggest the association of familial psychopathology and PTSD may be mediated by increased risk of traumatic exposure and by preexisting psychopathology...
  62. pmc Posttraumatic stress disorder; combat exposure; and nicotine dependence, alcohol dependence, and major depression in male twins
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, Research Service, St Louis, MO 63106, USA
    Compr Psychiatry 49:297-304. 2008
    ..These findings suggest comorbid PTSD may represent a genetically mediated vulnerability to psychopathology after trauma...
  63. pmc Research review: DSM-V conduct disorder: research needs for an evidence base
    Terrie E Moffitt
    Duke University, USA
    J Child Psychol Psychiatry 49:3-33. 2008
    ..We outline specific research questions and study designs needed to build the lacking evidence base for or against proposed changes to DSM-V conduct disorder...
  64. pmc Smoking predicts posttraumatic stress symptoms among rescue workers: a prospective study of ambulance personnel involved in the Enschede Fireworks Disaster
    Peter G van der Velden
    Institute for Psychotrauma IvP, Zaltbommel, The Netherlands
    Drug Alcohol Depend 94:267-71. 2008
    ..Examining whether smoking is a risk factor for posttraumatic stress disorder (PTSD) symptoms among rescue workers affected by a disaster...
  65. ncbi request reprint The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults
    Dean G Kilpatrick
    National Crime Victims Research and Treatment Center, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, P O Box 250852, Charleston, SC 29425, USA
    Am J Psychiatry 164:1693-9. 2007
    ....
  66. ncbi request reprint Continuing controversy over the psychological risks of Vietnam for U.S. veterans
    Bruce P Dohrenwend
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    J Trauma Stress 20:449-65. 2007
    ..1% current rates of war-related PTSD. The fact that these rates are lower than the original NVVRS rates has stimulated continuing controversy that has tended to obscure the more important implications of the study's results...
  67. pmc Differential etiology of posttraumatic stress disorder with conduct disorder and major depression in male veterans
    Qiang Fu
    Department of Community Health, Saint Louis University School of Public Health, St Louis, Missouri 63104, USA
    Biol Psychiatry 62:1088-94. 2007
    ..Epidemiologic studies reveal that posttraumatic stress disorder (PTSD) is highly comorbid with both conduct disorder and major depression in men. The genetic and environmental etiology of this comorbidity has not been examined...
  68. ncbi request reprint Pretrauma cognitive ability and risk for posttraumatic stress disorder: a twin study
    William S Kremen
    Department of Psychiatry and Center for Behavioral Genomics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Arch Gen Psychiatry 64:361-8. 2007
    ..Cognitive deficits are associated with posttraumatic stress disorder (PTSD), but whether such deficits reflect sequelae or risk factors is not fully resolved...
  69. pmc The psychological risks of Vietnam for U.S. veterans: a revisit with new data and methods
    Bruce P Dohrenwend
    New York State Psychiatric Institute, New York, NY 10032, USA
    Science 313:979-82. 2006
    ..7% of the veterans had developed war-related PTSD during their lifetimes and 9.1% were currently suffering from PTSD 11 to 12 years after the war; current PTSD was typically associated with moderate impairment...
  70. pmc Genetics of post-traumatic stress disorder: informing clinical conceptualizations and promoting future research
    Nicole R Nugent
    Brown Medical School and Bradley Hasbro Children s Research Center, USA
    Am J Med Genet C Semin Med Genet 148:127-32. 2008
    ..Finally, we summarize findings from molecular genetic studies, which have the potential to inform our understanding of underlying biological mechanisms for the development of PTSD...
  71. pmc Dissociation predicts later attention problems in sexually abused children
    Julie B Kaplow
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA
    Child Abuse Negl 32:261-75. 2008
    ..The goals of this research are to develop and test a prospective model of attention problems in sexually abused children that includes fixed variables (e.g., gender), trauma, and disclosure-related pathways...
  72. ncbi request reprint Helpseeking and access to mental health treatment for obsessive-compulsive disorder
    Renee Goodwin
    Department of Epidemiology, Maliman School of Public Health, Columbia University, New York, NY, USA
    Acta Psychiatr Scand 106:143-9. 2002
    ..To identify predictors of helpseeking and use of mental health treatment for obsessive-compulsive disorder (OCD) using the behavioral model of health service use...

Research Grants6

  1. Genetic Determinants of PTSD in Women
    Karestan C Koenen; Fiscal Year: 2010
    ....
  2. Development Epidemiology of PTSD
    Karestan Koenen; Fiscal Year: 2007
    ..This work will help the development of prevention and treatment interventions for traumatized individuals and will contribute to our understanding of the etiology of PTSD. ..
  3. Genetic Determinants of PTSD in Women
    Karestan Koenen; Fiscal Year: 2007
    ....
  4. Genetic Determinants of PTSD in Women
    Karestan Koenen; Fiscal Year: 2009
    ....