Ken Kleinman

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint A generalized linear mixed models approach for detecting incident clusters of disease in small areas, with an application to biological terrorism
    Ken Kleinman
    Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, MA 02215 3920, USA
    Am J Epidemiol 159:217-24. 2004
  2. doi request reprint Impact of a 16-community trial to promote judicious antibiotic use in Massachusetts
    Jonathan A Finkelstein
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Ave, Sixth Floor Boston, MA 02215, USA
    Pediatrics 121:e15-23. 2008
  3. pmc Medication adherence and racial differences in A1C control
    Alyce S Adams
    Ambulatory Care and Prevention, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 31:916-21. 2008
  4. doi request reprint Crossing growth percentiles in infancy and risk of obesity in childhood
    Elsie M Taveras
    Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Arch Pediatr Adolesc Med 165:993-8. 2011
  5. pmc Pneumococcal carriage and antibiotic resistance in young children before 13-valent conjugate vaccine
    Peter C Wroe
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pediatr Infect Dis J 31:249-54. 2012
  6. doi request reprint Trends in otitis media treatment failure and relapse
    Colin M Sox
    Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, USA
    Pediatrics 121:674-9. 2008
  7. ncbi request reprint Economic analysis of a randomized trial of academic detailing interventions to improve use of antihypertensive medications
    Steven R Simon
    Department of Ambulatory Care and Prevention, Harvard Medical School, Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Clin Hypertens (Greenwich) 9:15-20. 2007
  8. ncbi request reprint Clinical and nonclinical correlates of adherence to prescribing guidelines for hypertension in a large managed care organization
    Philip C Skelding
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Clin Hypertens (Greenwich) 8:414-9. 2006
  9. doi request reprint Similarity of the CDC and WHO weight-for-length growth charts in predicting risk of obesity at age 5 years
    Sheryl L Rifas-Shiman
    Obesity Prevention Program, Department of Population Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 20:1261-5. 2012
  10. pmc Epidemiology and risk factors for Staphylococcus aureus colonization in children in the post-PCV7 era
    Grace M Lee
    Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA, USA
    BMC Infect Dis 9:110. 2009

Detail Information

Publications68

  1. ncbi request reprint A generalized linear mixed models approach for detecting incident clusters of disease in small areas, with an application to biological terrorism
    Ken Kleinman
    Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, MA 02215 3920, USA
    Am J Epidemiol 159:217-24. 2004
    ..The authors argue that there is great value in using the geographic data...
  2. doi request reprint Impact of a 16-community trial to promote judicious antibiotic use in Massachusetts
    Jonathan A Finkelstein
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Ave, Sixth Floor Boston, MA 02215, USA
    Pediatrics 121:e15-23. 2008
    ..In addition, we sought to compare the intervention's impact on commercially and Medicaid-insured children...
  3. pmc Medication adherence and racial differences in A1C control
    Alyce S Adams
    Ambulatory Care and Prevention, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 31:916-21. 2008
    ..The purpose of this study was to examine medication adherence and other self-management practices as potential determinants of higher glycemic risk among black relative to white patients...
  4. doi request reprint Crossing growth percentiles in infancy and risk of obesity in childhood
    Elsie M Taveras
    Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Arch Pediatr Adolesc Med 165:993-8. 2011
    ..To examine the associations of upward crossing of major percentiles in weight-for-length in the first 24 months of life with the prevalence of obesity at ages 5 and 10 years...
  5. pmc Pneumococcal carriage and antibiotic resistance in young children before 13-valent conjugate vaccine
    Peter C Wroe
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Pediatr Infect Dis J 31:249-54. 2012
    ....
  6. doi request reprint Trends in otitis media treatment failure and relapse
    Colin M Sox
    Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, USA
    Pediatrics 121:674-9. 2008
    ....
  7. ncbi request reprint Economic analysis of a randomized trial of academic detailing interventions to improve use of antihypertensive medications
    Steven R Simon
    Department of Ambulatory Care and Prevention, Harvard Medical School, Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Clin Hypertens (Greenwich) 9:15-20. 2007
    ..Information on costs of academic detailing could assist with health plan decision making in developing interventions to improve prescribing...
  8. ncbi request reprint Clinical and nonclinical correlates of adherence to prescribing guidelines for hypertension in a large managed care organization
    Philip C Skelding
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Clin Hypertens (Greenwich) 8:414-9. 2006
    ..48-0.91). Patient age was not a significant correlate of adherence to guidelines (OR, 1.01; 95% CI, 0.94-1.09). Understanding these observations may lead to strategies to improve guideline adherence and reduce health care disparities...
  9. doi request reprint Similarity of the CDC and WHO weight-for-length growth charts in predicting risk of obesity at age 5 years
    Sheryl L Rifas-Shiman
    Obesity Prevention Program, Department of Population Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 20:1261-5. 2012
    ..7), respectively. Ever being overweight in the first 2 years of life is a strong predictor of obesity at 5 years. CDC WFL, WHO WFL, and WHO BMI cutpoints for overweight in early childhood provided similar estimates of later obesity risk...
  10. pmc Epidemiology and risk factors for Staphylococcus aureus colonization in children in the post-PCV7 era
    Grace M Lee
    Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA, USA
    BMC Infect Dis 9:110. 2009
    ..aureus and MRSA colonization in young children in the context of widespread use of PCV7; and (2) examine risk factors for S. aureus colonization in the post-PCV7 era, including the absence of vaccine-type S. pneumoniae colonization...
  11. doi request reprint Racial/ethnic differences in early-life risk factors for childhood obesity
    Elsie M Taveras
    Obesity Prevention Program, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, 133 Brookline Ave, 6th Floor, Boston, MA 02215, USA
    Pediatrics 125:686-95. 2010
    ..By the preschool years, racial/ethnic disparities in obesity prevalence are already present. The objective of this study was to examine racial/ethnic differences in early-life risk factors for childhood obesity...
  12. ncbi request reprint Relationship between patient medication adherence and subsequent clinical inertia in type 2 diabetes glycemic management
    Richard Grant
    General Medicine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 30:807-12. 2007
    ..We assessed the relationship between patients' initial medication adherence and subsequent regimen intensification among patients with persistently elevated A1C levels...
  13. ncbi request reprint Parental knowledge about antibiotic use: results of a cluster-randomized, multicommunity intervention
    Susan S Huang
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Ave, 6th Floor, Boston, MA 02215, USA
    Pediatrics 119:698-706. 2007
    ..The goal was to determine the impact of a community-wide educational intervention on parental misconceptions likely contributing to pediatric antibiotic overprescribing...
  14. pmc Early child care and adiposity at ages 1 and 3 years
    Sara E Benjamin
    Obesity Prevention Program, Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
    Pediatrics 124:555-62. 2009
    ..The majority of infants in the United States are in nonparental child care, yet little is known about the effect of child care on development of obesity...
  15. doi request reprint Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia
    Carlos A Camargo
    Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Pediatrics 130:e561-7. 2012
    ..We hypothesized that vitamin D supplementation of children with vitamin D deficiency would lower the risk of ARIs...
  16. pmc Childhood body mass index trajectories: modeling, characterizing, pairwise correlations and socio-demographic predictors of trajectory characteristics
    Xiaozhong Wen
    Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    BMC Med Res Methodol 12:38. 2012
    ..Prior studies of BMI trajectories are limited by restricted age periods and insufficient use of trajectory information...
  17. pmc Decreasing prevalence of obesity among young children in Massachusetts from 2004 to 2008
    Xiaozhong Wen
    Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Pediatrics 129:823-31. 2012
    ..To examine whether the obesity prevalence is increasing, level, or decreasing among young US children (aged <6 years) in the past decade; and to compare regional data to those of 2 national databases...
  18. pmc Developmental origins of childhood overweight: potential public health impact
    Matthew W Gillman
    Obesity Prevention Program, Department of Ambulatory Care and Prevention, Harvard Medical School Harvard Pilgrim Health Care, Boston, Massachusetts, USA
    Obesity (Silver Spring) 16:1651-6. 2008
    ..Interventions to modify several factors during pregnancy and infancy could have substantial impact on prevention of childhood overweight...
  19. doi request reprint Willingness to pay for a QALY based on community member and patient preferences for temporary health states associated with herpes zoster
    Tracy A Lieu
    Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, Massachusetts 02215, USA
    Pharmacoeconomics 27:1005-16. 2009
    ....
  20. doi request reprint Objective surveillance definitions for ventilator-associated pneumonia
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
    Crit Care Med 40:3154-61. 2012
    ..We explored the feasibility of creating objective surveillance definitions for ventilator-associated pneumonia...
  21. doi request reprint Use of Medicare claims to rank hospitals by surgical site infection risk following coronary artery bypass graft surgery
    Susan S Huang
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA
    Infect Control Hosp Epidemiol 32:775-83. 2011
    ..To evaluate whether longitudinal insurer claims data allow reliable identification of elevated hospital surgical site infection (SSI) rates...
  22. pmc Variation in hepatitis B immunization coverage rates associated with provider practices after the temporary suspension of the birth dose
    Nancy D Lin
    Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, MA, USA
    BMC Pediatr 6:31. 2006
    ....
  23. pmc Serotype specific invasive capacity and persistent reduction in invasive pneumococcal disease
    Inci Yildirim
    Department of Pediatrics, Boston University, School of Medicine, Boston, MA, USA
    Vaccine 29:283-8. 2010
    ..g. 33F, 22F) as successful colonizers resulting in increased IPD incidence due to replacement serotypes...
  24. ncbi request reprint Effects of race, insurance status, and hospital volume on perforated appendicitis in children
    Douglas S Smink
    Department of Surgery, Children s Hospital Boston, Boston, Massachusetts, USA
    Pediatrics 115:920-5. 2005
    ..We sought to investigate the association of perforated appendicitis in children with minority race, insurance status, and hospital volume...
  25. ncbi request reprint Community-level predictors of pneumococcal carriage and resistance in young children
    Susan S Huang
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA, USA
    Am J Epidemiol 159:645-54. 2004
    ..5, 95% confidence interval: 1.0, 11.7). The two- to threefold odds of pneumococcal carriage conferred by certain community characteristics suggest that these measures may target communities for interventions to decrease transmission...
  26. pmc Consumers' estimation of calorie content at fast food restaurants: cross sectional observational study
    Jason P Block
    Obesity Prevention Program, Department of Population Medicine, Harvard Medical School Harvard Pilgrim Health Care Institute, 133 Brookline Avenue, Boston, MA 02215, USA
    BMJ 346:f2907. 2013
    ..To investigate estimation of calorie (energy) content of meals from fast food restaurants in adults, adolescents, and school age children...
  27. doi request reprint Use of Medicare claims to identify US hospitals with a high rate of surgical site infection after hip arthroplasty
    Michael S Calderwood
    Departmentof Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts 02115, USA
    Infect Control Hosp Epidemiol 34:31-9. 2013
    ..To assess the ability of Medicare claims to identify US hospitals with high rates of surgical site infection (SSI) after hip arthroplasty...
  28. doi request reprint Effect of nonpayment for preventable infections in U.S. hospitals
    Grace M Lee
    Center for Child Health Care Studies, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA, USA
    N Engl J Med 367:1428-37. 2012
    ..The effect of this policy on rates of health care-associated infections is unknown...
  29. doi request reprint Uncontrolled asthma in a commercially insured population from 2002 to 2007: trends, predictors, and costs
    Gregory S Sawicki
    Division of Respiratory Diseases, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Asthma 47:574-80. 2010
    ..Uncontrolled asthma leads to preventable morbidity and increased health care utilization. The authors examined trends, predictors, and costs of uncontrolled asthma over 5 years in a large health plan population...
  30. ncbi request reprint Multivariate scan statistics for disease surveillance
    Martin Kulldorff
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Avenue, 6th Floor, Boston, MA 02215, USA
    Stat Med 26:1824-33. 2007
    ..The strongest signal was generated by a single data set and due to a familial outbreak of pinworm disease. The second and third strongest signals were generated by the combined strength of two of the three data sets...
  31. pmc Impact of the introduction of pneumococcal conjugate vaccine on immunization coverage among infants
    Nancy D Lin
    Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care, Harvard Medical School, Boston, MA, USA
    BMC Pediatr 5:43. 2005
    ..The purpose of this study was to evaluate whether introduction of PCV affected immunization coverage for recommended childhood vaccinations among 13-month olds in four large provider groups...
  32. pmc Vitamin D deficiency in pregnancy and gestational diabetes mellitus
    Heather H Burris
    Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Am J Obstet Gynecol 207:182.e1-8. 2012
    ..We examined the association of second-trimester maternal plasma 25-hydroxyvitamin D (25[OH]D) during pregnancy with gestational diabetes mellitus (GDM)...
  33. pmc Syndromic surveillance using minimum transfer of identifiable data: the example of the National Bioterrorism Syndromic Surveillance Demonstration Program
    Richard Platt
    Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Urban Health 80:i25-31. 2003
    ..If successful, this system will allow any organization with appropriate data to contribute vital information to public health syndromic surveillance systems while preserving individuals' privacy to the greatest extent possible...
  34. pmc Lifetime maternal experiences of abuse and risk of pre-natal depression in two demographically distinct populations in Boston
    Janet W Rich-Edwards
    Connors Center for Women s Health and Gender Biology, Brigham and Women s Hospital, Boston, MA, USA
    Int J Epidemiol 40:375-84. 2011
    ..To investigate lifetime history of interpersonal abuse and risk of pre-natal depression in socio-economically distinct populations in the same city...
  35. ncbi request reprint Community and patient values for preventing herpes zoster
    Tracy A Lieu
    Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, MA 02215, USA
    Pharmacoeconomics 26:235-49. 2008
    ....
  36. ncbi request reprint Preferences and willingness to pay for health states prevented by pneumococcal conjugate vaccine
    Lisa A Prosser
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
    Pediatrics 113:283-90. 2004
    ..To measure parents' and other adults' values for preventing disease associated with pneumococcal infection and to evaluate how including these values changes the economic appraisal of pneumococcal conjugate vaccine...
  37. doi request reprint Randomized trial of fortified milk and supplements to raise 25-hydroxyvitamin D concentrations in schoolchildren in Mongolia
    Janet W Rich-Edwards
    Connors Center for Women s Health and Gender Biology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 94:578-84. 2011
    ..The optimal public health strategy for maintaining 25-hydroxyvitamin D [25(OH)D] concentrations in schoolchildren in Mongolia is unknown...
  38. pmc Telephone triage service data for detection of influenza-like illness
    W Katherine Yih
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA, USA
    PLoS ONE 4:e5260. 2009
    ..Nontraditional sources of data for influenza and ILI surveillance are of interest to public health authorities if their validity can be established...
  39. doi request reprint Rapid and reproducible surveillance for ventilator-associated pneumonia
    Michael Klompas
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts 02215, USA
    Clin Infect Dis 54:370-7. 2012
    ..The complexity and subjectivity of ventilator-associated pneumonia (VAP) surveillance limit its value in assessing and comparing quality of care for ventilated patients. A simpler, more quantitative VAP definition may increase utility...
  40. ncbi request reprint Antibiotic-resistant Streptococcus pneumoniae in the heptavalent pneumococcal conjugate vaccine era: predictors of carriage in a multicommunity sample
    Jonathan A Finkelstein
    Department of Ambulatory Care and Prevention, Harvard Medical School HPHC, Boston, Massachusetts 02215, USA
    Pediatrics 112:862-9. 2003
    ..Data on carriage of resistant organisms by healthy children in communities in which immunization with PCV7 has been implemented will help to define and decrease these risks further...
  41. ncbi request reprint Race differences in long-term diabetes management in an HMO
    Alyce S Adams
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Ave, 6th Floor, Boston, MA 02215, USA
    Diabetes Care 28:2844-9. 2005
    ..We examined race differences in diabetes outcomes over 4-8 years in a single HMO...
  42. pmc Antecedents of obesity - analysis, interpretation, and use of longitudinal data
    Matthew W Gillman
    Obesity Prevention Program, Department of Ambulatory Care and Prevention, Harvard Medical School Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Am J Epidemiol 166:14-6; author reply 17-8. 2007
    ..Ultimately, interventions in these factors may help prevent obesity-related adverse health outcomes for future generations...
  43. ncbi request reprint Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age
    Carlos A Camargo
    Center for D receptor Activation Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Clin Nutr 85:788-95. 2007
    ..Vitamin D deficiency and asthma are common at higher latitudes. Although vitamin D has important immunologic effects, its relation with asthma is unknown...
  44. pmc Duration of lactation and maternal metabolism at 3 years postpartum
    Alison M Stuebe
    Division of Maternal Fetal Medicine, Department of Obstetrics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Womens Health (Larchmt) 19:941-50. 2010
    ..Lactation has been associated with reduced risk of type 2 diabetes and the metabolic syndrome in mothers. We examined the relation between breastfeeding duration and metabolic markers at 3 years postpartum...
  45. ncbi request reprint Incidence of outpatient visits and hospitalizations related to influenza in infants and young children
    Megan A O'Brien
    Center for Child Health Care Studies, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
    Pediatrics 113:585-93. 2004
    ....
  46. pmc Using automated health plan data to assess infection risk from coronary artery bypass surgery
    Richard Platt
    Centers for Disease Control and Prevention Eastern Massachusetts Prevention Epicenter, Boston, USA
    Emerg Infect Dis 8:1433-41. 2002
    ....
  47. pmc Milk consumption and the prepubertal somatotropic axis
    Janet W Rich-Edwards
    Connors Center for Women s Health and Gender Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Nutr J 6:28. 2007
    ..We conducted pilot studies in Mongolia and Massachusetts to test the extent to which milk intake raised somatotropic hormone concentrations in prepubertal children...
  48. ncbi request reprint Group versus individual academic detailing to improve the use of antihypertensive medications in primary care: a cluster-randomized controlled trial
    Steven R Simon
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Avenue 6th Floor, Boston, MA 02215, USA
    Am J Med 118:521-8. 2005
    ..To compare group versus individual academic detailing to increase diuretic or beta-blocker use in hypertension...
  49. pmc Sociodemographic predictors of antenatal and postpartum depressive symptoms among women in a medical group practice
    Janet W Rich-Edwards
    Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Epidemiol Community Health 60:221-7. 2006
    ..This study investigated whether race/ethnicity, age, finances, and partnership status were associated with antenatal and postpartum depressive symptoms...
  50. pmc Use of automated ambulatory-care encounter records for detection of acute illness clusters, including potential bioterrorism events
    Ross Lazarus
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Emerg Infect Dis 8:753-60. 2002
    ..This system complements emergency room- and hospital-based surveillance by adding the capacity to rapidly identify clusters of illness, including potential bioterrorism events...
  51. ncbi request reprint Intercenter variation in initial management of children with Crohn's disease
    Michael D Kappelman
    Center for Inflammatory Bowel Disease, Division of Gastroenterology and Nutrition, Children s Hospital Boston, Massachusetts 02115, USA
    Inflamm Bowel Dis 13:890-5. 2007
    ..We undertook this study to determine the extent of intercenter variation in the initial management of children newly diagnosed with Crohn's disease...
  52. pmc Gumbel based p-value approximations for spatial scan statistics
    Allyson M Abrams
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, USA
    Int J Health Geogr 9:61. 2010
    ..A drawback to this powerful technique is that each additional digit of p-value precision requires ten times as many replicated datasets, and the additional processing can lead to excessive run times...
  53. pmc Differential association of modifiable health behaviors with hot flashes in perimenopausal and postmenopausal women
    Erika Hyde Riley
    Department of Ambulatory Care and Prevention, Harvard Medical School, Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Gen Intern Med 19:740-6. 2004
    ..To determine the association of modifiable factors, such as smoking, body mass index, and alcohol use, with hot flashes, and to ascertain whether the association with hot flashes varies by menopausal stage...
  54. ncbi request reprint The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States
    Michael D Kappelman
    Center for Inflammatory Bowel Disease, Division of Gastroenterology and Nutrition, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA
    Clin Gastroenterol Hepatol 5:1424-9. 2007
    ..This study sought to determine the prevalence of Crohn's disease (CD) and ulcerative colitis (UC) in a large national sample and to compare the prevalence across geographic regions and other sociodemographic characteristics...
  55. ncbi request reprint Correlates of parental antibiotic knowledge, demand, and reported use
    Marianne Kuzujanakis
    Harvard Pediatric Health Sevices Research Fellowship, The Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Mass 02215, USA
    Ambul Pediatr 3:203-10. 2003
    ..Clinicians cite parental misconceptions and requests for antibiotics as reasons for inappropriate prescribing...
  56. doi request reprint Development of an algorithm for surveillance of ventilator-associated pneumonia with electronic data and comparison of algorithm results with clinician diagnoses
    Michael Klompas
    Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, Massachusetts, USA
    Infect Control Hosp Epidemiol 29:31-7. 2008
    ..We sought to improve the efficiency and objectivity of VAP surveillance by adapting the CDC criteria to make them amenable to evaluation with electronic data...
  57. ncbi request reprint Evaluating spatial surveillance: detection of known outbreaks in real data
    Ken Kleinman
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, USA
    Stat Med 25:755-69. 2006
    ..They can be used to assess whether the new system works in that it detects the outbreaks better than chance would suggest and can also determine if the new systems' signals are generated earlier than an extant system...
  58. doi request reprint Cluster randomized trials in comparative effectiveness research: randomizing hospitals to test methods for prevention of healthcare-associated infections
    Richard Platt
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Med Care 48:S52-7. 2010
    ..The need for evidence about the effectiveness of therapeutics and other medical practices has triggered new interest in methods for comparative effectiveness research...
  59. pmc Health care transition in patients with type 1 diabetes: young adult experiences and relationship to glycemic control
    Katharine C Garvey
    Division of Endocrinology, Children s Hospital Boston, Boston, Massachusetts, USA
    Diabetes Care 35:1716-22. 2012
    ..To examine characteristics of the transition from pediatric to adult care in emerging adults with type 1 diabetes and evaluate associations between transition characteristics and glycemic control...
  60. pmc Longitudinal study of birth weight and adult body mass index in predicting risk of coronary heart disease and stroke in women
    Janet W Rich-Edwards
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Avenue, Boston, MA 02215, USA
    BMJ 330:1115. 2005
    ..To determine whether birth weight and adult body size interact to predict coronary heart disease in women, as has been observed for men. To determine whether birth weight and adult body size interact to predict risk of stroke...
  61. ncbi request reprint The effect of hospital volume of pediatric appendectomies on the misdiagnosis of appendicitis in children
    Douglas S Smink
    Harvard Pediatric Health Services Research Fellowship, Department of Surgery, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatrics 113:18-23. 2004
    ....
  62. doi request reprint Electronic health records and malpractice claims in office practice
    Anunta Virapongse
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Ave, Sixth Floor, Boston, MA 02215, USA
    Arch Intern Med 168:2362-7. 2008
    ..Electronic health records (EHRs) may improve patient safety and health care quality, but the relationship between EHR adoption and settled malpractice claims is unknown...
  63. ncbi request reprint Pediatricians' views on financial barriers and values for pneumococcal vaccine for children
    Tracy A Lieu
    Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, 133 Brookline Avenue, 6th Floor, Boston, MA 02215, USA
    Ambul Pediatr 2:358-66. 2002
    ..To 1) describe barriers to pneumococcal conjugate vaccine adoption and 2) estimate the value of the vaccine based on pediatricians' responses to willingness-to-pay questions...
  64. ncbi request reprint A trial of disclosing physicians' financial incentives to patients
    Steven D Pearson
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Arch Intern Med 166:623-8. 2006
    ..Concern regarding financial conflict of interest for physicians has led to calls for disclosure of financial incentives to patients. However, limited data on the outcomes of disclosure exist to guide policy...
  65. pmc Physician responses to a community-level trial promoting judicious antibiotic use
    Christopher J Stille
    Meyers Primary Care Institute, Worcester, Massachusetts 01655, USA
    Ann Fam Med 6:206-12. 2008
    ..We assessed physician responses to a community-level intervention with respect to antibiotic prescribing, related practices, and perceived effectiveness...
  66. pmc Simulated anthrax attacks and syndromic surveillance
    James D Nordin
    HealthPartners Research Foundation, Minneapolis, Minnesota 55440 1524, USA
    Emerg Infect Dis 11:1394-8. 2005
    ..Timeliness and completeness of detection of events varied by rate of infection. First detection of events ranged from days 3 to 6. Similar modeling may be possible with other surveillance systems and should be a part of their evaluation...
  67. ncbi request reprint Multi-syndrome analysis of time series using PCA: a new concept for outbreak investigation
    Mojdeh Mohtashemi
    MITRE Corporation, Bedford, MA 01730, USA
    Stat Med 26:5203-24. 2007
    ....
  68. ncbi request reprint Four different study designs to evaluate vaccine safety were equally validated with contrasting limitations
    Jason M Glanz
    Clinical Research Unit, Kaiser Permanente, P O Box 378006, Colorado, Denver, CO 80237 8066, USA
    J Clin Epidemiol 59:808-18. 2006
    ..We conducted a simulation study to empirically compare four study designs [cohort, case-control, risk-interval, self-controlled case series (SCCS)] used to assess vaccine safety...