Evangelos Kiskinis

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Progress toward the clinical application of patient-specific pluripotent stem cells
    Evangelos Kiskinis
    The Stowers Medical Institute, Harvard Stem Cell Institute, Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA
    J Clin Invest 120:51-9. 2010
  2. pmc A functionally characterized test set of human induced pluripotent stem cells
    Gabriella L Boulting
    The Howard Hughes Medical Institute, Cambridge, Massachusetts, USA
    Nat Biotechnol 29:279-86. 2011
  3. pmc Erosion of dosage compensation impacts human iPSC disease modeling
    Shila Mekhoubad
    The Harvard Stem Cell Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA
    Cell Stem Cell 10:595-609. 2012
  4. ncbi request reprint Genetic validation of a therapeutic target in a mouse model of ALS
    A Sophie de Boer
    The Howard Hughes Medical Institute, Harvard Stem Cell Institute, Stanley Center for Psychiatric Research, Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands
    Sci Transl Med 6:248ra104. 2014
  5. ncbi request reprint Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1
    Evangelos Kiskinis
    The Howard Hughes Medical Institute, USA Harvard Stem Cell Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA 02138, USA
    Cell Stem Cell 14:781-95. 2014
  6. doi request reprint Shushing down the epigenetic landscape towards stem cell differentiation
    Justin K Ichida
    The Howard Hughes Medical Institute, Stowers Medical Institute, Harvard Stem Cell Institute and the Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA
    Development 137:2455-60. 2010
  7. pmc Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines
    Christoph Bock
    Broad Institute, Cambridge, MA 02142, USA
    Cell 144:439-52. 2011

Collaborators

Detail Information

Publications7

  1. pmc Progress toward the clinical application of patient-specific pluripotent stem cells
    Evangelos Kiskinis
    The Stowers Medical Institute, Harvard Stem Cell Institute, Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA
    J Clin Invest 120:51-9. 2010
    ....
  2. pmc A functionally characterized test set of human induced pluripotent stem cells
    Gabriella L Boulting
    The Howard Hughes Medical Institute, Cambridge, Massachusetts, USA
    Nat Biotechnol 29:279-86. 2011
    ..This iPSC and ESC test set is a robust resource for those interested in the basic biology of stem cells and their applications...
  3. pmc Erosion of dosage compensation impacts human iPSC disease modeling
    Shila Mekhoubad
    The Harvard Stem Cell Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA
    Cell Stem Cell 10:595-609. 2012
    ..However, our finding that most genes subject to XCI are derepressed by this erosion of XCI suggests that it should be a significant consideration when selecting hiPSC lines for modeling any disease...
  4. ncbi request reprint Genetic validation of a therapeutic target in a mouse model of ALS
    A Sophie de Boer
    The Howard Hughes Medical Institute, Harvard Stem Cell Institute, Stanley Center for Psychiatric Research, Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands
    Sci Transl Med 6:248ra104. 2014
    ..Our findings suggest that blocking DP1 may be a therapeutic strategy in ALS and demonstrate that discoveries from stem cell models of disease can be corroborated in vivo. ..
  5. ncbi request reprint Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1
    Evangelos Kiskinis
    The Howard Hughes Medical Institute, USA Harvard Stem Cell Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA 02138, USA
    Cell Stem Cell 14:781-95. 2014
    ..Finally, interrogation of stem-cell-derived motor neurons produced from ALS patients harboring a repeat expansion in C9orf72 indicates that at least a subset of these changes are more broadly conserved in ALS. ..
  6. doi request reprint Shushing down the epigenetic landscape towards stem cell differentiation
    Justin K Ichida
    The Howard Hughes Medical Institute, Stowers Medical Institute, Harvard Stem Cell Institute and the Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA
    Development 137:2455-60. 2010
    ....
  7. pmc Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines
    Christoph Bock
    Broad Institute, Cambridge, MA 02142, USA
    Cell 144:439-52. 2011
    ..The combination of assays yields a scorecard for quick and comprehensive characterization of pluripotent cell lines...