Ivana K Kim

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity
    Bao Jian Fan
    Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
    BMC Med Genet 9:5. 2008
  2. doi request reprint Natural history of radiation papillopathy after proton beam irradiation of parapapillary melanoma
    Ivana K Kim
    Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthalmology 117:1617-22. 2010
  3. doi request reprint Survival in patients with presymptomatic diagnosis of metastatic uveal melanoma
    Ivana K Kim
    Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Arch Ophthalmol 128:871-5. 2010
  4. ncbi request reprint Melanocytoma of the optic nerve associated with sound-induced phosphenes
    Ivana K Kim
    Retina Service, Massachusetts Eye and Ear Infirmary, Boston 02114, USA
    Arch Ophthalmol 124:273-7. 2006
  5. ncbi request reprint Effect of intravitreal injection of ranibizumab in combination with verteporfin PDT on normal primate retina and choroid
    Ivana K Kim
    Angiogenesis and Laser Laboratory, Retina Research Institute, Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 47:357-63. 2006
  6. pmc Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration
    Ivana K Kim
    Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Mol Vis 14:1487-95. 2008
  7. pmc Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration
    Michael T Andreoli
    Ocular Molecular Genetics Institute, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 148:869-74. 2009
  8. doi request reprint Anti-vascular endothelial growth factor monotherapy versus combination treatment with photodynamic therapy for subfoveal choroidal neovascularization secondary to causes other than age-related macular degeneration
    Ling Chen
    Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA
    Retina 31:2078-83. 2011
  9. pmc Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics
    Michael Feehan
    Ocular Molecular Genetics Institute and the Retina Service, Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    BMC Med Genet 12:83. 2011
  10. doi request reprint Proton irradiation for peripapillary and parapapillary melanomas
    Anne Marie Lane
    Retina Service, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Arch Ophthalmol 129:1127-30. 2011

Collaborators

Detail Information

Publications29

  1. pmc DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity
    Bao Jian Fan
    Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
    BMC Med Genet 9:5. 2008
    ....
  2. doi request reprint Natural history of radiation papillopathy after proton beam irradiation of parapapillary melanoma
    Ivana K Kim
    Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthalmology 117:1617-22. 2010
    ..To evaluate the natural history of radiation papillopathy after proton beam irradiation of parapapillary choroidal melanoma...
  3. doi request reprint Survival in patients with presymptomatic diagnosis of metastatic uveal melanoma
    Ivana K Kim
    Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Arch Ophthalmol 128:871-5. 2010
    ..To determine if patients diagnosed as having metastatic uveal melanoma before the onset of symptoms experience more favorable survival outcomes than patients diagnosed after the onset of symptoms...
  4. ncbi request reprint Melanocytoma of the optic nerve associated with sound-induced phosphenes
    Ivana K Kim
    Retina Service, Massachusetts Eye and Ear Infirmary, Boston 02114, USA
    Arch Ophthalmol 124:273-7. 2006
  5. ncbi request reprint Effect of intravitreal injection of ranibizumab in combination with verteporfin PDT on normal primate retina and choroid
    Ivana K Kim
    Angiogenesis and Laser Laboratory, Retina Research Institute, Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 47:357-63. 2006
    ..San Francisco, CA) directed against vascular endothelial growth factor (VEGF) in combination with verteporfin photodynamic therapy (PDT) on normal primate retina and choroid...
  6. pmc Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration
    Ivana K Kim
    Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Mol Vis 14:1487-95. 2008
    ..Additionally we examined the degree to which CRP common variation was in linkage disequilibrium (LD) within our cohort...
  7. pmc Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration
    Michael T Andreoli
    Ocular Molecular Genetics Institute, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 148:869-74. 2009
    ..To examine the interaction of genotypic variation of 16 single-nucleotide polymorphisms (SNP) in the complement factor H (CFH) and LOC387715/ARMS2/HTRA1 loci with clinical characteristics of age-related macular degeneration (AMD)...
  8. doi request reprint Anti-vascular endothelial growth factor monotherapy versus combination treatment with photodynamic therapy for subfoveal choroidal neovascularization secondary to causes other than age-related macular degeneration
    Ling Chen
    Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA
    Retina 31:2078-83. 2011
    ..To compare the visual outcomes and retreatment rates of monotherapy with intravitreal bevacizumab versus combination with photodynamic therapy for choroidal neovascularization secondary to causes other than age-related macular degeneration...
  9. pmc Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics
    Michael Feehan
    Ocular Molecular Genetics Institute and the Retina Service, Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    BMC Med Genet 12:83. 2011
    ..In the present study, we identify patient subtypes or clusters which could represent several different targets for treatment development, based on genetic pathways in AMD and cardiovascular pathology...
  10. doi request reprint Proton irradiation for peripapillary and parapapillary melanomas
    Anne Marie Lane
    Retina Service, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Arch Ophthalmol 129:1127-30. 2011
    ..To examine ocular outcomes and survival after proton irradiation in patients with peripapillary and parapapillary melanomas ineligible for the Collaborative Ocular Melanoma Study...
  11. doi request reprint Genetics of age-related macular degeneration: current concepts, future directions
    Margaret M DeAngelis
    Ocular Molecular Genetics Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA
    Semin Ophthalmol 26:77-93. 2011
    ..Moreover, these studies provide the foundation for further investigation into the pathophysiology of AMD by utilizing a systems-biology-based approach to elucidate underlying mechanistic pathways...
  12. pmc Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration
    Margaux A Morrison
    Ocular Molecular Genetics Institute, Harvard Medical School, Massachusetts Eye and Ear, Boston, MA, USA
    Hum Genomics 5:538-68. 2011
    ..These data not only extend previous biological studies in the AMD field, but further emphasise common antecedents between several disorders with an inflammatory/immunogenic component such as cardiovascular disease, cancer and AMD...
  13. doi request reprint Mortality after diagnosis of small melanocytic lesions of the choroid
    Anne Marie Lane
    Massachusetts Eye and Ear Infirmary, Boston, USA
    Arch Ophthalmol 128:996-1000. 2010
    ..To evaluate the risk of dying of metastatic choroidal melanoma in patients with small, indeterminate, pigmented lesions of the uveal tract...
  14. pmc Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach
    Alexandra C Silveira
    Ocular Molecular Genetics Institute and Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    Vision Res 50:698-715. 2010
    ..Moreover, we found a significant interaction between RORA and the ARMS2/HTRA1 locus suggesting a novel pathway underlying AMD pathophysiology...
  15. pmc Age-related macular degeneration-associated silent polymorphisms in HtrA1 impair its ability to antagonize insulin-like growth factor 1
    Sarah Melissa P Jacobo
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    Mol Cell Biol 33:1976-90. 2013
    ..These observations highlight the relevance of synonymous codon usage to protein function and implicate homeostatic protein quality control mechanisms that may go awry in NvAMD...
  16. pmc High throughput mass spectrometry-based mutation profiling of primary uveal melanoma
    Anthony B Daniels
    Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114 3096, USA
    Invest Ophthalmol Vis Sci 53:6991-6. 2012
    ..We assessed for mutations in a large number of oncogenes and tumor suppressor genes in primary uveal melanomas using a high-throughput profiling system...
  17. pmc The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration
    Hong Zhang
    Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    BMC Med Genet 9:51. 2008
    ..Conditional logistic regression was used to determine significant gene-gene interactions. LRT was used to determine the best fit for each genotypic model tested (additive, dominant or recessive)...
  18. doi request reprint Conversion to aflibercept for chronic refractory or recurrent neovascular age-related macular degeneration
    Yoshihiro Yonekawa
    Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Am J Ophthalmol 156:29-35.e2. 2013
    ..To explore the visual and anatomic outcomes of patients with refractory or recurrent neovascular age-related macular degeneration (AMD) who were converted from bevacizumab and/or ranibizumab to aflibercept...
  19. doi request reprint Intravitreal injections at the Massachusetts Eye and Ear Infirmary: analysis of treatment indications and postinjection endophthalmitis rates
    Miriam Englander
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Br J Ophthalmol 97:460-5. 2013
    ..To report the incidence rate of acute postoperative endophthalmitis secondary to therapeutic intravitreal injections...
  20. doi request reprint Proton beam irradiation using a light-field technique for the treatment of choroidal hemangiomas
    R V Paul Chan
    Retina Service, New York Presbyterian Hospital, Weill Cornell Medical College, New York, NY, USA
    Ophthalmologica 224:209-16. 2010
    ..To describe the clinical outcomes of patients with circumscribed and diffuse choroidal hemangiomas treated by proton beam irradiation using a nonsurgical light-field technique...
  21. doi request reprint Ranibizumab for choroidal neovascularization secondary to causes other than age-related macular degeneration: a phase I clinical trial
    Jeffrey S Heier
    Ophthalmic Consultants of Boston, Boston, Massachusetts, USA
    Ophthalmology 118:111-8. 2011
    ..To investigate the safety and efficacy of ranibizumab for the treatment of choroidal neovascularization (CNV) secondary to causes other than age-related macular degeneration (AMD)...
  22. pmc Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1
    Hyeong Gon Yu
    Angiogenesis Laboratory and Laser Laboratory, Retina Research Institute, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 49:2599-605. 2008
    ..This study investigated the influence of defective elastic fiber maintenance in the development of laser-induced CNV...
  23. ncbi request reprint Cigarette smoking, CFH, APOE, ELOVL4, and risk of neovascular age-related macular degeneration
    Margaret M DeAngelis
    Department of Ophthalmology, Harvard Medical School, and Massachusetts Eye and Ear Infirmary, Boston, USA
    Arch Ophthalmol 125:49-54. 2007
    ....
  24. doi request reprint Epidemiology and management of uveal melanoma
    Yoshihiro Yonekawa
    Department of Ophthalmology, Harvard Medical School, Retina Service, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Hematol Oncol Clin North Am 26:1169-84. 2012
    ..Continued advances in understanding of the molecular mechanisms of uveal melanoma will facilitate the identification of prognostic markers and therapeutic targets...
  25. pmc Utilizing targeted gene therapy with nanoparticles binding alpha v beta 3 for imaging and treating choroidal neovascularization
    Hani Salehi-Had
    Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 6:e18864. 2011
    ..We investigated whether a novel intravenously injectable αvβ3 integrin-ligand coupled nanoparticle (NP) can target choroidal neovascular membranes (CNV) for imaging and targeted gene therapy...
  26. doi request reprint Pseudophakic cystoid macular edema
    Yoshihiro Yonekawa
    Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Curr Opin Ophthalmol 23:26-32. 2012
    ..This article systematically reviews and discusses the epidemiology, risk factors, diagnosis, and treatment of PCME, with a focus on advances in the past 1-2 years...
  27. doi request reprint Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration
    Margaret M DeAngelis
    Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthalmology 115:1209-1215.e7. 2008
    ....
  28. ncbi request reprint Successful treatment of Fusarium endophthalmitis with voriconazole and Aspergillus endophthalmitis with voriconazole plus caspofungin
    Marlene L Durand
    Infectious Disease Service, Massachusetts Eye and Ear Infirmary MEEI, 243 Charles Street, Boston, MA 02114, USA
    Am J Ophthalmol 140:552-4. 2005
    ..To report successful treatment of exogenous Fusarium and Aspergillus endophthalmitis with new antifungal agents...
  29. ncbi request reprint Management of dislocated lens material
    Ivana K Kim
    Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    Semin Ophthalmol 17:162-6. 2002
    ..Therefore, if both the anterior segment and vitreoretinal surgeons rigorously avoid vitreous traction in these cases, a good visual prognosis is expected...