Research Topics
Species | Molly L KileSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Variability in biomarkers of arsenic exposure and metabolism in adults over timeMolly L Kile
Harvard School of Public Health, Boston, Massachusetts 02115, USA
Environ Health Perspect 117:455-60. 2009..Urinary arsenic metabolites (UAs) are used as biomarkers of exposure and metabolism...
Correlation of global and gene-specific DNA methylation in maternal-infant pairsMolly L Kile
Environmental Health Department, Harvard School of Public Health, Boston, Massachusetts, United States of America
PLoS ONE 5:e13730. 2010..Future studies should also use a multi-generational family-based design that would quantify both maternal and paternal contributions to DNA methylation in offspring across more than one generation...
A pathway-based analysis of urinary arsenic metabolites and skin lesionsMolly L Kile
Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
Am J Epidemiol 173:778-86. 2011..This novel analysis confirmed that persons who excrete a higher proportion of MMA have a greater risk of skin lesions after data are adequately controlled for urinary arsenic metabolites, current arsenic exposure, and other risk factors...
Association between total ingested arsenic and toenail arsenic concentrationsMolly L Kile
Harvard School of Public Health, Boston, Massachusetts 02115, USA
J Environ Sci Health A Tox Hazard Subst Environ Eng 42:1827-34. 2007..26-0.38) explained the most variability in toenail arsenic concentrations (R(2)(a)=0.71). The effect estimates for food and drinking water are similar suggesting that both sources have a similar contribution to internal dose...
Dietary arsenic exposure in bangladeshMolly L Kile
Harvard School of Public Health, Boston, Massachusetts 02115, USA
Environ Health Perspect 115:889-93. 2007..Millions of people in Bangladesh are at risk of chronic arsenic toxicity from drinking contaminated groundwater, but little is known about diet as an additional source of As exposure...
Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking waterMolly L Kile
Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 14:2419-26. 2005..11; 95% CI, 0.06-0.2). Therefore, it seems that GSTT1 modifies the relationship between As(in) exposure and toenail As(in) content...
GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures studyCarrie V Breton
Harvard School of Public Health, Dept of Environmental Health, 665 Huntington Avenue, Boston, MA 02115, USA
Environ Health 6:39. 2007..Chronic arsenic exposure is associated with an increased risk of skin, bladder and lung cancers. Generation of oxidative stress may contribute to arsenic carcinogenesis...
Gender-specific protective effect of hemoglobin on arsenic-induced skin lesionsCarrie V Breton
Department of Environmental Health, Harvard School of Public Health, Room 1420, Building I, 665 Huntington Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 15:902-7. 2006....
Susceptibility to arsenic-induced skin lesions from polymorphisms in base excision repair genesCarrie V Breton
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Carcinogenesis 28:1520-5. 2007..Future research on arsenic-induced skin lesions should consider the impact of genetic variation to individual susceptibility to arsenic toxicity...
Maternal arsenic exposure associated with low birth weight in BangladeshKaren L Huyck
Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
J Occup Environ Med 49:1097-104. 2007..To characterize the effects of maternal arsenic exposure on birth weight...
Antimony: an unlikely confounder in the relationship between well water arsenic and health outcomes in BangladeshKathleen M McCarty
Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
Environ Health Perspect 112:809-11. 2004....
Arsenic reduction in drinking water and improvement in skin lesions: a follow-up study in BangladeshWei Jie Seow
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Environ Health Perspect 120:1733-8. 2012..Chronic exposure to arsenic is associated with skin lesions. However, it is not known whether reducing arsenic exposure will improve skin lesions...
Can folate intake reduce arsenic toxicity?Molly L Kile
Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, Massachsetts, USA
Nutr Rev 66:349-53. 2008..Although no studies have directly shown that high folate intake reduces the risk of arsenic toxicity, these findings provide evidence to support an interaction between folate and arsenic metabolism...
Environmental arsenic exposure and diabetesMolly L Kile
JAMA 300:845-6. 2008
