Molly L Kile

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking water
    Molly L Kile
    Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:2419-26. 2005
  2. pmc A pathway-based analysis of urinary arsenic metabolites and skin lesions
    Molly L Kile
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 173:778-86. 2011
  3. pmc Dietary arsenic exposure in bangladesh
    Molly L Kile
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 115:889-93. 2007
  4. ncbi request reprint Association between total ingested arsenic and toenail arsenic concentrations
    Molly L Kile
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Environ Sci Health A Tox Hazard Subst Environ Eng 42:1827-34. 2007
  5. pmc Correlation of global and gene-specific DNA methylation in maternal-infant pairs
    Molly L Kile
    Environmental Health Department, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 5:e13730. 2010
  6. pmc Variability in biomarkers of arsenic exposure and metabolism in adults over time
    Molly L Kile
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 117:455-60. 2009
  7. pmc GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study
    Carrie V Breton
    Harvard School of Public Health, Dept of Environmental Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Environ Health 6:39. 2007
  8. ncbi request reprint Gender-specific protective effect of hemoglobin on arsenic-induced skin lesions
    Carrie V Breton
    Department of Environmental Health, Harvard School of Public Health, Room 1420, Building I, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:902-7. 2006
  9. pmc Genetic susceptible locus in NOTCH2 interacts with arsenic in drinking water on risk of type 2 diabetes
    Wen Chi Pan
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 8:e70792. 2013
  10. pmc Arsenic reduction in drinking water and improvement in skin lesions: a follow-up study in Bangladesh
    Wei Jie Seow
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 120:1733-8. 2012

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking water
    Molly L Kile
    Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:2419-26. 2005
    ..11; 95% CI, 0.06-0.2). Therefore, it seems that GSTT1 modifies the relationship between As(in) exposure and toenail As(in) content...
  2. pmc A pathway-based analysis of urinary arsenic metabolites and skin lesions
    Molly L Kile
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 173:778-86. 2011
    ..This novel analysis confirmed that persons who excrete a higher proportion of MMA have a greater risk of skin lesions after data are adequately controlled for urinary arsenic metabolites, current arsenic exposure, and other risk factors...
  3. pmc Dietary arsenic exposure in bangladesh
    Molly L Kile
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 115:889-93. 2007
    ..Millions of people in Bangladesh are at risk of chronic arsenic toxicity from drinking contaminated groundwater, but little is known about diet as an additional source of As exposure...
  4. ncbi request reprint Association between total ingested arsenic and toenail arsenic concentrations
    Molly L Kile
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Environ Sci Health A Tox Hazard Subst Environ Eng 42:1827-34. 2007
    ..26-0.38) explained the most variability in toenail arsenic concentrations (R(2)(a)=0.71). The effect estimates for food and drinking water are similar suggesting that both sources have a similar contribution to internal dose...
  5. pmc Correlation of global and gene-specific DNA methylation in maternal-infant pairs
    Molly L Kile
    Environmental Health Department, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 5:e13730. 2010
    ..Future studies should also use a multi-generational family-based design that would quantify both maternal and paternal contributions to DNA methylation in offspring across more than one generation...
  6. pmc Variability in biomarkers of arsenic exposure and metabolism in adults over time
    Molly L Kile
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 117:455-60. 2009
    ..Urinary arsenic metabolites (UAs) are used as biomarkers of exposure and metabolism...
  7. pmc GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study
    Carrie V Breton
    Harvard School of Public Health, Dept of Environmental Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Environ Health 6:39. 2007
    ..Chronic arsenic exposure is associated with an increased risk of skin, bladder and lung cancers. Generation of oxidative stress may contribute to arsenic carcinogenesis...
  8. ncbi request reprint Gender-specific protective effect of hemoglobin on arsenic-induced skin lesions
    Carrie V Breton
    Department of Environmental Health, Harvard School of Public Health, Room 1420, Building I, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:902-7. 2006
    ....
  9. pmc Genetic susceptible locus in NOTCH2 interacts with arsenic in drinking water on risk of type 2 diabetes
    Wen Chi Pan
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 8:e70792. 2013
    ..Chronic exposure to arsenic in drinking water is associated with increased risk of type 2 diabetes mellitus (T2DM) but the underlying molecular mechanism remains unclear...
  10. pmc Arsenic reduction in drinking water and improvement in skin lesions: a follow-up study in Bangladesh
    Wei Jie Seow
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 120:1733-8. 2012
    ..Chronic exposure to arsenic is associated with skin lesions. However, it is not known whether reducing arsenic exposure will improve skin lesions...
  11. ncbi request reprint Maternal arsenic exposure associated with low birth weight in Bangladesh
    Karen L Huyck
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    J Occup Environ Med 49:1097-104. 2007
    ..To characterize the effects of maternal arsenic exposure on birth weight...
  12. ncbi request reprint Susceptibility to arsenic-induced skin lesions from polymorphisms in base excision repair genes
    Carrie V Breton
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Carcinogenesis 28:1520-5. 2007
    ..Future research on arsenic-induced skin lesions should consider the impact of genetic variation to individual susceptibility to arsenic toxicity...
  13. pmc Epigenome-wide DNA methylation changes with development of arsenic-induced skin lesions in Bangladesh: A case-control follow-up study
    Wei Jie Seow
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts
    Environ Mol Mutagen 55:449-56. 2014
    ..Environ. Mol. Mutagen. 55:449-456, 2014. © 2014 Wiley Periodicals, Inc. ..
  14. pmc Antimony: an unlikely confounder in the relationship between well water arsenic and health outcomes in Bangladesh
    Kathleen M McCarty
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Environ Health Perspect 112:809-11. 2004
    ....
  15. pmc Inverse association between toenail arsenic and body mass index in a population of welders
    Rachel Grashow
    Department of Environmental Health, Harvard School of Public Health, Landmark Center, 401 Park Drive, 3rd Floor, Boston, MA 02215, USA Electronic address
    Environ Res 131:131-3. 2014
    ..It is unclear whether low arsenic biomarker concentrations in high BMI subjects truly reflect lower exposures, or instead reflect internal or metabolic changes that alter arsenic metabolism and tissue deposition. ..
  16. pmc Can folate intake reduce arsenic toxicity?
    Molly L Kile
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, Massachsetts, USA
    Nutr Rev 66:349-53. 2008
    ..Although no studies have directly shown that high folate intake reduces the risk of arsenic toxicity, these findings provide evidence to support an interaction between folate and arsenic metabolism...
  17. pmc Environmental arsenic exposure and diabetes
    Molly L Kile
    JAMA 300:845-6. 2008