Research Topics
| Dan K KielySummaryAffiliation: Harvard University Country: USA Publications
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Publications
Association between psychomotor activity delirium subtypes and mortality among newly admitted post-acute facility patientsDan K Kiely
Hebrew SeniorLife, Institute for Aging Research, Boston, MA 02131, USA
J Gerontol A Biol Sci Med Sci 62:174-9. 2007..The purpose of this study is to examine the association between psychomotor activity delirium subtypes and 1-year mortality among 457 newly admitted delirious PAC patients...
Persistent delirium predicts greater mortalityDan K Kiely
Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131 1097, USA
J Am Geriatr Soc 57:55-61. 2009..To examine the association between persistent delirium and 1-year mortality in newly admitted postacute care (PAC) facility patients with delirium who were followed regardless of residence...- Health care proxy grief symptoms before the death of nursing home residents with advanced dementiaDan K Kiely
Hebrew Senior Life, Institute for Aging Research, Center for Psychosocial Oncology and Palliative Care Research, Dana Farber Cancer Institute, Boston, Massachusetts, USA
Am J Geriatr Psychiatry 16:664-73. 2008.... - Validation and comparison of two frailty indexes: The MOBILIZE Boston StudyDan K Kiely
Institute for Aging Research, Hebrew SeniorLife, 1200 Centre St, Boston, MA 02131, USA
J Am Geriatr Soc 57:1532-9. 2009..To validate two established frailty indexes and compare their ability to predict adverse outcomes in a diverse, elderly, community-dwelling sample of men and women... - Hospice use and outcomes in nursing home residents with advanced dementiaDan K Kiely
Hebrew SeniorLife Institute for Aging Research, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 58:2284-91. 2010.... - The clinical course of advanced dementiaSusan L Mitchell
Hebrew SeniorLife Institute for Aging Research, Boston, MA 02131, USA
N Engl J Med 361:1529-38. 2009..Dementia is a leading cause of death in the United States but is underrecognized as a terminal illness. The clinical course of nursing home residents with advanced dementia has not been well described... - Are changes in leg power responsible for clinically meaningful improvements in mobility in older adults?Jonathan F Bean
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts, USA
J Am Geriatr Soc 58:2363-8. 2010..From among physiological attributes commonly targeted in rehabilitation, to identify those in which changes led to clinically meaningful differences (CMDs) in mobility outcomes... - Chronic musculoskeletal pain and the occurrence of falls in an older populationSuzanne G Leveille
Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, MA, USA
JAMA 302:2214-21. 2009..Chronic pain is a major contributor to disability in older adults; however, the potential role of chronic pain as a risk factor for falls is poorly understood... - Phenomenological subtypes of delirium in older persons: patterns, prevalence, and prognosisFrances M Yang
Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA
Psychosomatics 50:248-54. 2009..Delirium is an acute confusional state that is common, preventable, and life-threatening... - Frailty and the degradation of complex balance dynamics during a dual-task protocolHyun Gu Kang
Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA
J Gerontol A Biol Sci Med Sci 64:1304-11. 2009.... - Increased Velocity Exercise Specific to Task (InVEST) training: a pilot study exploring effects on leg power, balance, and mobility in community-dwelling older womenJonathan F Bean
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA
J Am Geriatr Soc 52:799-804. 2004..To evaluate a dynamic form of weighted vest exercise suitable for home use and designed to enhance muscle power, balance, and mobility... - Telephone interview for cognitive status: Creating a crosswalk with the Mini-Mental State ExaminationTamara G Fong
Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA
Alzheimers Dement 5:492-7. 2009..Screening instruments such as the Telephone Interview for Cognitive Status (TICS) were developed to provide a valid alternative, with comparable cut-point scores to rate global cognitive function... - Participation in activity and risk for incident deliriumFrances M Yang
Department of Psychiatry, Brigham and Woman s Hospital, Boston, Massachusetts, USA
J Am Geriatr Soc 56:1479-84. 2008..To examine the mediating role between educational attainment and risk for incidence delirium of activity participation and to examine the contribution of participation in specific activities to the development of delirium... - Survival and comfort after treatment of pneumonia in advanced dementiaJane L Givens
Division of Gerontology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Arch Intern Med 170:1102-7. 2010..The objective of this study was to examine the effect of antimicrobial treatment for suspected pneumonia on survival and comfort in patients with advanced dementia... - Randomized trial of a delirium abatement program for postacute skilled nursing facilitiesEdward R Marcantonio
Divisions of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02446, USA
J Am Geriatr Soc 58:1019-26. 2010..To determine whether a delirium abatement program (DAP) can shorten duration of delirium in new admissions to postacute care (PAC)... 
Which impairments are most associated with high mobility performance in older adults? Implications for a rehabilitation prescriptionJonathan F Bean
Department of Physical Medicine, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, MA, USA
Arch Phys Med Rehabil 89:2278-84. 2008..To test which rehabilitative impairments are associated with higher mobility performance among community-dwelling, mobility-limited older adults...- Outcomes of older people admitted to postacute facilities with deliriumEdward R Marcantonio
Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
J Am Geriatr Soc 53:963-9. 2005..To compare outcomes of patients admitted to postacute skilled nursing facilities with delirium, subsyndromal delirium, and no delirium... - Grief among family members of nursing home residents with advanced dementiaJane L Givens
Hebrew SeniorLife Institute for Aging Research, Beth Israel Deaconess Medical Center, Division of Gerontology, Boston, MA, USA
Am J Geriatr Psychiatry 19:543-50. 2011..To describe preloss and postloss grief symptoms among family members of nursing home (NH) residents with advanced dementia, and to identify predictors of greater postloss grief symptoms... - Advanced dementia research in the nursing home: the CASCADE studySusan L Mitchell
Hebrew Senior Life Institute for Aging Research, Department of Medicine of Beth Israel Deaconess Medical Center, Boston, MA, USA
Alzheimer Dis Assoc Disord 20:166-75. 2006..The CASCADE experience establishes the feasibility of conducting rigorous, multisite dementia NH research, and the described methodology serves as a detailed reference for subsequent CASCADE publications as results from the study emerge... - Prediction of 6-month survival of nursing home residents with advanced dementia using ADEPT vs hospice eligibility guidelinesSusan L Mitchell
The Hebrew Senior Life, Institute for Aging Research, Boston, Massachusetts, USA
JAMA 304:1929-35. 2010..Estimating life expectancy is challenging in advanced dementia, potentially limiting the use of hospice care in these patients... - Characteristics associated with delirium persistence among newly admitted post-acute facility patientsDan K Kiely
Research and Training Institute, Hebrew Rehabilitation Center for Aged, Boston, Massachusetts 02131, USA
J Gerontol A Biol Sci Med Sci 59:344-9. 2004.... - Trunk muscle attributes are associated with balance and mobility in older adults: a pilot studyPradeep Suri
Department of PM and R, Harvard Medical School, Boston, MA, USA
PM R 1:916-24. 2009..To determine whether trunk muscle attributes are associated with balance and mobility performance among mobility-limited older adults... - Occurrence and treatment of suspected pneumonia in long-term care residents dying with advanced dementiaJen Hau Chen
Hebrew SeniorLife, Research and Training Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 54:290-5. 2006..To describe the occurrence and management of suspected pneumonia in end-stage dementia and to identify factors associated with aggressiveness of antibiotic treatment... - Associating the onset of motor impairments with disability progression in nursing home residentsJonathan Bean
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital and the Hebrew Rehabilitation Center for Aged, Research and Training Institute, Boston, Massachusetts 02131, USA
Am J Phys Med Rehabil 81:696-704; quiz 705-7, 720. 2002..CONCLUSION: This study directly links the onset of movement impairments with disability progression. These findings have important implications for physiatrists and other practitioners of geriatric rehabilitation... - Increased trunk extension endurance is associated with meaningful improvement in balance among older adults with mobility problemsPradeep Suri
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA, USA
Arch Phys Med Rehabil 92:1038-43. 2011..To determine whether trunk extension endurance changes with training are associated with clinically meaningful improvements in balance among mobility-limited older adults... - Risk factors for delirium at discharge: development and validation of a predictive modelSharon K Inouye
Aging Brain Center, Hebrew SeniorLife, 1200 Centre St, Boston, MA 02131, USA
Arch Intern Med 167:1406-13. 2007..Persistent delirium at the time of hospital discharge is associated with poor outcomes. The objectives of this study were to develop and validate a predictive model for persistent delirium at hospital discharge... - Terminal trajectories of functional decline in the long-term care settingJen Hau Chen
Hebrew SeniorLife, Institute for Aging Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
J Gerontol A Biol Sci Med Sci 62:531-6. 2007..Little is known about the terminal trajectories of functional decline among long-term care (LTC) residents dying with different diseases... - Prevalence of delirium on admission to postacute care is associated with a higher number of nursing home deficienciesRichard N Jones
Institute for Aging Research, Hebrew SeniorLife, Boston, MA 02131, USA
J Am Med Dir Assoc 11:253-6. 2010..To examine the association between the prevalence of delirium among patients admitted to postacute care and the quality of nursing home care as reflected in deficiency counts... - Association between delirium resolution and functional recovery among newly admitted postacute facility patientsDan K Kiely
Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts, USA
J Gerontol A Biol Sci Med Sci 61:204-8. 2006..The purpose of this study is to examine the association between delirium resolution and functional recovery in skilled nursing facilities specializing in PAC... - The 6-minute walk test in mobility-limited elders: what is being measured?Jonathan F Bean
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA
J Gerontol A Biol Sci Med Sci 57:M751-6. 2002..Though commonly utilized as an outcome measure among otherwise healthy mobility-limited elders, it is not clear whether the 6mw best represents a measure of functional limitation, aerobic capacity, or both... - Dying with advanced dementia in the nursing homeSusan L Mitchell
Research and Training Institute, Hebrew Rehabilitation Center for Aged, Boston, MA 02131, USA
Arch Intern Med 164:321-6. 2004..Nursing homes are important providers of end-of-life care to persons with advanced dementia... - The validity and reliability of scales for the evaluation of end-of-life care in advanced dementiaDan K Kiely
Hebrew SeniorLife Institute for Aging Research, Boston, MA, USA
Alzheimer Dis Assoc Disord 20:176-81. 2006..81). The results of this study demonstrate that the 3 EOLD scales demonstrate "internal consistency" reliability and demonstrate convergent validity, and further establish their utility in palliative care dementia research... - Nursing home patients in the intensive care unit: Risk factors for mortalityMelissa L P Mattison
Department of Medicine, Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, USA
Crit Care Med 34:2583-7. 2006..Among hospital survivors, impaired functional status is independently associated with increased mortality rate within 90 days... - Enhanced vasoreactivity and its response to antihypertensive therapy in hypertensive elderly womenLewis A Lipsitz
Hebrew SeniorLife, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Hypertension 47:377-83. 2006..These results highlight the beneficial effects of antihypertensive therapy on the systemic vasculature, particularly for elderly women in whom enhanced vasoreactivity may contribute to excessive cardiovascular morbidity and mortality... - Upper and lower limb muscle power relationships in mobility-limited older adultsSeth Herman
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, MA, USA
J Gerontol A Biol Sci Med Sci 60:476-80. 2005..Additionally, upper limb muscle power measures may serve as a useful surrogate measure of limb power having implications for clinicians and researchers... - A model for management of delirious postacute care patientsMargaret A Bergmann
Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
J Am Geriatr Soc 53:1817-25. 2005..Program adoption challenges and corresponding model refinements to enhance adherence and overall care quality are highlighted. Last, clinical adaptation of this research-derived program is discussed... - The association of educational attainment and SBP among older community-living adults: the Maintenance of Balance, Independent Living, Intellect and Zest in the Elderly (MOBILIZE) Boston StudyDan K Kiely
Institute for Aging Research, Hebrew Senior Life, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02131, USA
J Hypertens 30:1518-25. 2012..Educational attainment is inversely associated with SBP level in young adulthood. This association has not been studied in an older cohort, and confounding and mediating factors are not well known... - Geriatric syndromes in older homeless adultsRebecca T Brown
Division of Gerontology of Beth Israel Deaconess Medical Center, Boston, MA 02131, USA
J Gen Intern Med 27:16-22. 2012..The average age of the US homeless population is increasing. Little is known about the prevalence of geriatric syndromes in older homeless adults... - Hypertension, orthostatic hypotension, and the risk of falls in a community-dwelling elderly population: the maintenance of balance, independent living, intellect, and zest in the elderly of Boston studyAnupama Gangavati
Division of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
J Am Geriatr Soc 59:383-9. 2011..1)... - Estimating prognosis for nursing home residents with advanced dementiaSusan L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, The Harvard Medical School, Boston, Mass 02131, USA
JAMA 291:2734-40. 2004..Survival varies for patients with advanced dementia, and accurate prognostic tools have not been developed. A small proportion of patients admitted to hospice have dementia, in part because of the difficulty in predicting survival... - Healthcare proxies of nursing home residents with advanced dementia: decisions they confront and their satisfaction with decision-makingJane L Givens
Division of Gerontology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
J Am Geriatr Soc 57:1149-55. 2009..To describe the medical decisions confronting healthcare proxies (HCPs) of nursing home (NH) residents with advanced dementia and to identify factors associated with greater decision-making satisfaction... - Increased velocity exercise specific to task training versus the National Institute on Aging's strength training program: changes in limb power and mobilityJonathan F Bean
Department of Physical Medicine and Rehabilitation, Harvard Medical School, and Spaulding Rehabilitation Hospital, Boston, MA, USA
J Gerontol A Biol Sci Med Sci 64:983-91. 2009..This study was designed to evaluate the benefits of InVEST (Increased Velocity Specific to Task) training on limb power and mobility among mobility-limited older adults... - Decisions to hospitalize nursing home residents dying with advanced dementiaJennifer L Lamberg
Hebrew SeniorLife, Research and Training Institute, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 53:1396-401. 2005..Thus, hospital transfers are common near the end of life. The finding that DNH orders are associated with patient and surrogate factors can help clinicians identify cases in which decisions to forgo hospitalizations may be facilitated... - Do attitudes toward exercise vary with differences in mobility and disability status? - a study among low-income seniorsJonathan F Bean
Department PM and R, Harvard Medical School, Boston, MA, USA
Disabil Rehabil 29:1215-20. 2007..To examine attitudes toward exercise among a vulnerable aged population characterized by low socioeconomic status, poor functional status and lack of available therapeutic exercise resources... - Is stair climb power a clinically relevant measure of leg power impairments in at-risk older adults?Jonathan F Bean
Department of PM and R, Harvard Medical School, Boston, MA, USA
Arch Phys Med Rehabil 88:604-9. 2007..To test the clinical relevance of the stair climb power test (SCPT) as a measure of leg power impairments in mobility-limited older adults... - Hospice care for patients with dementiaSusan L Mitchell
Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131, USA
J Pain Symptom Manage 34:7-16. 2007..These data suggest that the evaluation of hospice care for older patients is generally high, and does not vary with respect to terminal diagnoses... - Influence of poststroke urinary incontinence on disability: the nursing home settingJonathan F Bean
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA
Am J Phys Med Rehabil 82:175-81. 2003..These findings have clinical implications for physiatrists and nursing home clinicians and provide a context in which future disability research can be conducted... - Weighted stair climbing in mobility-limited older people: a pilot studyJonathan Bean
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA
J Am Geriatr Soc 50:663-70. 2002..To evaluate weighted stair climbing exercise (SCE) as a means of increasing lower extremity muscle power in mobility-limited older people... - Neurovascular coupling is impaired in slow walkers: the MOBILIZE Boston StudyFarzaneh A Sorond
Department of Neurology, Stroke Division, Brigham and Women s Hospital, Women s Hospital, Boston, MA 02115, USA
Ann Neurol 70:213-20. 2011..Our study examines the association between neurovascular coupling in the middle cerebral artery and gait speed in elderly individuals with impaired cerebral vasoreactivity... - Delirium among newly admitted postacute facility patients: prevalence, symptoms, and severityDan K Kiely
Hebrew Rehabilitation Center for Aged, Research and Training Institute, 1200 Centre Street, Boston, MA 02131, USA
J Gerontol A Biol Sci Med Sci 58:M441-5. 2003..The purpose of this study is to describe the prevalence of delirium, delirium symptoms, and severity assessed at admission to postacute facilities... - A comparison of leg power and leg strength within the InCHIANTI study: which influences mobility more?Jonathan F Bean
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, and Hebrew Rehabilitation Center for the Aged, Boston, Massachusetts 02131, USA
J Gerontol A Biol Sci Med Sci 58:728-33. 2003..There was also evidence that the power-function relationship may be described as curvilinear. However, these findings have never been confirmed in a representative population... - Does educational attainment contribute to risk for delirium? A potential role for cognitive reserveRichard N Jones
Institute for Aging Research, Hebrew SeniorLife, Boston, MA 02131, USA
J Gerontol A Biol Sci Med Sci 61:1307-11. 2006..The objective of this study was to determine if level of educational attainment, a marker of cognitive reserve, was associated with the cumulative risk of delirium among hospitalized elders... - The protective effect of social engagement on 1-year mortality in a long-stay nursing home populationDan K Kiely
The Hebrew Rehabilitation Center for Aged Research and Training Institute, 1200 Centre Street, Boston, MA 02131 1097, USA
J Clin Epidemiol 56:472-8. 2003..Future studies are needed to understand psychological and other factors related to residents' capacity and motivation for social engagement that could increase quality and quantity of life in nursing home residents... - Is pulse pressure a predictor of cardiovascular complications in a frail elderly nursing home population?Morad Askari
Hebrew Rehabilitation Center for Aged Research and Training Institute, Boston, MA 02131, USA
Aging Clin Exp Res 16:206-11. 2004..The aims of this project are to determine the value of PP in predicting CV complications in a nursing home population, and to compare its predictive value with SBP, DBP, and mean arterial pressure (MAP)... - Prevalence and characteristics of traumatic intracranial hemorrhage in elderly fallers presenting to the emergency department without focal findingsAnupama S Gangavati
Department of Medicine, Division of Gerontology, Beth Israel Deaconess Medical Center, Massachusetts 02215, USA
J Am Geriatr Soc 57:1470-4. 2009..To determine the prevalence and associated characteristics of traumatic intracranial hemorrhage (ICH) in elderly fallers presenting to the emergency department (ED) without focal findings... - The study of pathogen resistance and antimicrobial use in dementia: study design and methodologySusan L Mitchell
Hebrew SeniorLife Institute for Aging Research, Boston, MA 02131, United States
Arch Gerontol Geriatr 56:16-22. 2013.... - Antihypertensive therapy increases cerebral blood flow and carotid distensibility in hypertensive elderly subjectsLewis A Lipsitz
Hebrew Rehabilitation Center for Aged, Boston, MA 02131, USA
Hypertension 45:216-21. 2005..Treatment reduced cerebrovascular resistance and did not impair cerebral autoregulation. Therefore, judicious long-term treatment of systolic hypertension in otherwise healthy elderly subjects does not cause cerebral hypoperfusion... - Nursing home characteristics associated with tube feeding in advanced cognitive impairmentSusan L Mitchell
Hebrew Rehabilitation Center for Aged Research and Training Institute, Harvard Medical School, Boston, Massachusetts 02131, USA
J Am Geriatr Soc 51:75-9. 2003..To identify nursing homes factors associated with the use of tube feeding in advanced cognitive impairment... - Selective impairment of frontal-executive cognitive function in african americans with cardiovascular risk factorsKenneth G Pugh
Beth Israel Deaconess Medical Center, Department of Medicine, Gerontology Division, Boston, Massachusetts, USA
J Am Geriatr Soc 51:1439-44. 2003..To determine whether a summary cardiovascular risk score is associated with an increased risk of frontal-executive cognitive impairment... - Factors associated with physician and nurse practitioner pressure ulcer staging practices in rehabilitative and long term careE Foy White-Chu
Department of Medicine, Hebrew SeniorLife, Boston, MA 02131, USA
J Am Med Dir Assoc 13:748-51. 2012..Future research that is adequately powered is needed to replicate these results and detect other potential factors associated with documentation... - The relationship between leg power and physical performance in mobility-limited older peopleJonathan F Bean
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA
J Am Geriatr Soc 50:461-7. 2002..The purpose of this study was to assess the influence of leg power and leg strength on the physical performance of community-dwelling mobility-limited older people... - Mortality-related factors and 1-year survival in nursing home residentsJonathan M Flacker
Division of Geriatric Medicine and Gerontology, Emory University School of Medicine, Atlanta, Georgia 30303, USA
J Am Geriatr Soc 51:213-21. 2003.... - Hospice care for patients with dementia: does volume make a difference?Susan C Miller
Center for Gerontology and Health Care Research, Department of Community Health, The Warren Alpert Medical School of Brown University, Providence, RI 02912, USA
J Pain Symptom Manage 35:283-91. 2008..Further study is needed to understand the nonintuitive negative association between higher volume and lower satisfaction. This study emphasizes the need for examination of quality outcomes by profit status... - Satisfaction with end-of-life care for nursing home residents with advanced dementiaSharon E Engel
School of Medicine, Emory University, Atlanta, Georgia 30306, USA
J Am Geriatr Soc 54:1567-72. 2006..To identify factors associated with satisfaction with care for healthcare proxies (HCPs) of nursing home (NH) residents with advanced dementia... - Does gynecologic surgery contribute to low back problems in later life? An analysis of the women's health and aging studyJeffery J Ericksen
Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, 23298, USA
Arch Phys Med Rehabil 87:172-6. 2006..To examine whether women with potential injuries to the abdominal and pelvic musculature from past gynecologic surgery are at higher risk for low back pain (LBP)...