M A Kelliher
Affiliation: Harvard University
- The death domain kinase RIP mediates the TNF-induced NF-kappaB signalM A Kelliher
Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
Immunity 8:297-303. 1998..Sensitivity to TNFalpha-mediated cell death in rip-/- cells is accompanied by a failure to activate the transcription factor NF-kappaB...
- Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalphaM A Kelliher
Department of Genetics, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA 02115, USA
EMBO J 15:5160-6. 1996..These studies prove that dysregulated tal-1 is oncogenic, providing a direct molecular explanation for the malignancies associated with TAL-1 activation in human T-ALL...
- RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFRD B Ramnarain
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390 8813, USA
Cell Death Differ 15:344-53. 2008..Thus, our study identifies a new link between inflammatory and growth factor signaling pathways mediated by RIP1 and provides insight into the mechanism used by RIP1 to regulate EGFR levels...