M J Kaufman

Summary

Affiliation: Harvard Medical School
Country: USA

Publications

  1. ncbi request reprint Cocaine-induced cerebral vasoconstriction detected in humans with magnetic resonance angiography
    M J Kaufman
    Brain Imaging Center, McLean Hospital, Consolidated Department of Psychiatry, Harvard Medical School, Belmont, Mass 02178, USA
    JAMA 279:376-80. 1998
  2. ncbi request reprint Cocaine decreases relative cerebral blood volume in humans: a dynamic susceptibility contrast magnetic resonance imaging study
    M J Kaufman
    Brain Imaging Center, McLean Hospital, Belmont, MA 02178, USA
    Psychopharmacology (Berl) 138:76-81. 1998
  3. ncbi request reprint Cocaine administration induces human splenic constriction and altered hematologic parameters
    M J Kaufman
    Brain Imaging Center, McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, USA
    J Appl Physiol 85:1877-83. 1998
  4. ncbi request reprint Cerebral phosphorus metabolite abnormalities in opiate-dependent polydrug abusers in methadone maintenance
    M J Kaufman
    Brain Imaging Center, McLean Hospital, MA 02478, USA
    Psychiatry Res 90:143-52. 1999
  5. ncbi request reprint Illicit cocaine use patterns in intravenous-naive cocaine users following investigational intravenous cocaine administration
    M J Kaufman
    Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA
    Drug Alcohol Depend 58:35-42. 2000
  6. ncbi request reprint Cocaine-induced cerebral vasoconstriction differs as a function of sex and menstrual cycle phase
    M J Kaufman
    Brain Imaging Center, Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 49:774-81. 2001
  7. ncbi request reprint Reduction in BOLD fMRI response to primary visual stimulation following alcohol ingestion
    J M Levin
    Laboratory for Cerebral Blood Flow, McLean Hospital, Belmont, MA 02178, USA
    Psychiatry Res 82:135-46. 1998
  8. ncbi request reprint Cocaine-induced erythrocytosis and increase in von Willebrand factor: evidence for drug-related blood doping and prothrombotic effects
    A J Siegel
    Department of Medicine, McLean Hospital, Belmont, Mass 02478, USA
    Arch Intern Med 159:1925-9. 1999
  9. ncbi request reprint Influence of baseline hematocrit and hemodilution on BOLD fMRI activation
    J M Levin
    Laboratory for Cerebral Blood Flow, Brain Imaging Center, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA
    Magn Reson Imaging 19:1055-62. 2001
  10. ncbi request reprint Brain kinetics of paroxetine and fluoxetine on the third day of placebo substitution: a fluorine MRS study
    M E Henry
    McLean Hospital, Belmont, MA 02478, USA
    Am J Psychiatry 157:1506-8. 2000

Detail Information

Publications14

  1. ncbi request reprint Cocaine-induced cerebral vasoconstriction detected in humans with magnetic resonance angiography
    M J Kaufman
    Brain Imaging Center, McLean Hospital, Consolidated Department of Psychiatry, Harvard Medical School, Belmont, Mass 02178, USA
    JAMA 279:376-80. 1998
    ..Clinical observations and case reports suggest that there are important cerebrovascular complications of cocaine use, but no studies have documented a direct link...
  2. ncbi request reprint Cocaine decreases relative cerebral blood volume in humans: a dynamic susceptibility contrast magnetic resonance imaging study
    M J Kaufman
    Brain Imaging Center, McLean Hospital, Belmont, MA 02178, USA
    Psychopharmacology (Berl) 138:76-81. 1998
    ..These data suggest that DSC-MRI can detect cocaine-induced CBV reductions indicative of vasoconstriction, and that it may be useful for evaluating treatments designed to reduce the cerebrovascular effects of cocaine...
  3. ncbi request reprint Cocaine administration induces human splenic constriction and altered hematologic parameters
    M J Kaufman
    Brain Imaging Center, McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, USA
    J Appl Physiol 85:1877-83. 1998
    ..These events may help to preserve or increase tissue oxygenation in periods of high oxygen demand and/or increased vascular resistance...
  4. ncbi request reprint Cerebral phosphorus metabolite abnormalities in opiate-dependent polydrug abusers in methadone maintenance
    M J Kaufman
    Brain Imaging Center, McLean Hospital, MA 02478, USA
    Psychiatry Res 90:143-52. 1999
    ..The nearly normal metabolite profile in long-term MMT subjects suggests that prolonged MMT may be associated with improved neurochemistry...
  5. ncbi request reprint Illicit cocaine use patterns in intravenous-naive cocaine users following investigational intravenous cocaine administration
    M J Kaufman
    Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA
    Drug Alcohol Depend 58:35-42. 2000
    ..These data suggest that illicit cocaine use frequencies and routes of administration are not altered following investigational intravenous cocaine administration to healthy, occasional cocaine users...
  6. ncbi request reprint Cocaine-induced cerebral vasoconstriction differs as a function of sex and menstrual cycle phase
    M J Kaufman
    Brain Imaging Center, Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 49:774-81. 2001
    ..These findings imply that gonadal steroids or the factors they modulate merit study as possible therapeutic agents for reducing cocaine-induced cerebrovascular disorders...
  7. ncbi request reprint Reduction in BOLD fMRI response to primary visual stimulation following alcohol ingestion
    J M Levin
    Laboratory for Cerebral Blood Flow, McLean Hospital, Belmont, MA 02178, USA
    Psychiatry Res 82:135-46. 1998
    ....
  8. ncbi request reprint Cocaine-induced erythrocytosis and increase in von Willebrand factor: evidence for drug-related blood doping and prothrombotic effects
    A J Siegel
    Department of Medicine, McLean Hospital, Belmont, Mass 02478, USA
    Arch Intern Med 159:1925-9. 1999
    ..Mechanisms that mediate cocaine-induced cardiovascular events following vasoconstriction are incompletely understood...
  9. ncbi request reprint Influence of baseline hematocrit and hemodilution on BOLD fMRI activation
    J M Levin
    Laboratory for Cerebral Blood Flow, Brain Imaging Center, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA
    Magn Reson Imaging 19:1055-62. 2001
    ..Finally, the robust agreement between predicted and empiric data serves to validate a semiquantitative approach to the analysis of BOLD fMRI data...
  10. ncbi request reprint Brain kinetics of paroxetine and fluoxetine on the third day of placebo substitution: a fluorine MRS study
    M E Henry
    McLean Hospital, Belmont, MA 02478, USA
    Am J Psychiatry 157:1506-8. 2000
    ..This study tested whether a relationship exists between concentration and response following discontinuation of selective serotonin reuptake inhibitors...
  11. ncbi request reprint Functional magnetic resonance imaging of human brain activation during cue-induced cocaine craving
    L C Maas
    Brain Imaging Center, McLean Hospital, Belmont, MA 02178, USA
    Am J Psychiatry 155:124-6. 1998
    ..Functional magnetic resonance imaging (MRI) was used to test whether brain activation was detectable in regions previously associated with cocaine cue-induced craving...
  12. ncbi request reprint Test-retest reliability of DSC MRI CBV mapping in healthy volunteers
    M E Henry
    Brain Imaging Center, McLean Hospital and The Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA
    Neuroreport 12:1567-9. 2001
    ..08, with a coefficient of variation of 12%. The correlation between scans was 0.84 (p < 0.0001). The data presented here support the hypothesis that DSC MRI CBV mapping has acceptable test-retest reliability...
  13. ncbi request reprint Altropane, a SPECT or PET imaging probe for dopamine neurons: II. Distribution to dopamine-rich regions of primate brain
    B K Madras
    Dept of Psychiatry, Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts 01772 9102, USA
    Synapse 29:105-15. 1998
    ..The selective binding of altropane to the dopamine-rich striatum within 30 min of i.v. administration indicates that it is uniquely suited for SPECT or PET imaging of the dopamine transporter and associated dopamine neurons...
  14. ncbi request reprint Brain T2 relaxation times correlate with regional cerebral blood volume
    C M Anderson
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    MAGMA 18:3-6. 2005
    ..007;r = 0.782,p = 0.004, respectively). These correlations predict 9 +/- 3% and 10 +/- 3% rCBV changes, respectively, for each 1-msec change in T2. Consequently, brain T2 measurements may be useful for estimating steady-state rCBV...