Adolf W Karchmer

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Methicillin-resistant Staphylococcus aureus: an evolving clinical challenge
    Adolf W Karchmer
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Clin Infect Dis 46:S342-3. 2008
  2. ncbi request reprint Increased antibiotic resistance in respiratory tract pathogens: PROTEKT US--an update
    Adolf W Karchmer
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215 5399, USA
    Clin Infect Dis 39:S142-50. 2004
  3. doi request reprint Bloodstream infections: the problem and the challenge
    Adolf W Karchmer
    Harvard Medical School, Division of Infectious Diseases, Beth Israel Deaconess Medical Center, 110 Francis Street, Suite GB, Boston, MA 02215, USA
    Int J Antimicrob Agents 34:S2-4. 2009
  4. doi request reprint Risk factors for albicans and non-albicans candidemia in the intensive care unit
    Jennifer K Chow
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
    Crit Care Med 36:1993-8. 2008
  5. doi request reprint Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children: executive summary
    Catherine Liu
    Department of Medicine, Division of Infectious Diseases, University of California San Francisco, San Francisco, California 94102, USA
    Clin Infect Dis 52:285-92. 2011
  6. pmc r-metHuLeptin improves highly active antiretroviral therapy-induced lipoatrophy and the metabolic syndrome, but not through altering circulating IGF and IGF-binding protein levels: observational and interventional studies in humans
    Aoife M Brennan
    Division of Endocrinology, Diabetes, and Metabolism, Harvard Medical School, Beth Israel Deaconess Medical Center, E St 816, 330 Brookline Avenue, Boston, Massachusetts 02215, USA
    Eur J Endocrinol 160:173-6. 2009
  7. doi request reprint Initial low-dose gentamicin for Staphylococcus aureus bacteremia and endocarditis is nephrotoxic
    Sara E Cosgrove
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Clin Infect Dis 48:713-21. 2009
  8. doi request reprint Factors associated with candidemia caused by non-albicans Candida species versus Candida albicans in the intensive care unit
    Jennifer K Chow
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Clin Infect Dis 46:1206-13. 2008
  9. pmc Adherence to Mediterranean diet is favorably associated with metabolic parameters in HIV-positive patients with the highly active antiretroviral therapy-induced metabolic syndrome and lipodystrophy
    Sotiris Tsiodras
    Division of Infectious Diseases, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Metabolism 58:854-9. 2009
  10. doi request reprint Development of reduced vancomycin susceptibility in methicillin-susceptible Staphylococcus aureus
    Satish K Pillai
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Infect Dis 49:1169-74. 2009

Detail Information

Publications32

  1. doi request reprint Methicillin-resistant Staphylococcus aureus: an evolving clinical challenge
    Adolf W Karchmer
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Clin Infect Dis 46:S342-3. 2008
  2. ncbi request reprint Increased antibiotic resistance in respiratory tract pathogens: PROTEKT US--an update
    Adolf W Karchmer
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215 5399, USA
    Clin Infect Dis 39:S142-50. 2004
    ..The patterns of resistance detected by these major surveillance programs are a warning signal regarding the continued emergence of resistance among community-acquired respiratory tract pathogens...
  3. doi request reprint Bloodstream infections: the problem and the challenge
    Adolf W Karchmer
    Harvard Medical School, Division of Infectious Diseases, Beth Israel Deaconess Medical Center, 110 Francis Street, Suite GB, Boston, MA 02215, USA
    Int J Antimicrob Agents 34:S2-4. 2009
    ..Application of simple principles of intravenous catheter placement and maintenance can markedly reduce nosocomial BSI. Although treatment of BSI can be difficult, the greatest challenge is preventing these infections...
  4. doi request reprint Risk factors for albicans and non-albicans candidemia in the intensive care unit
    Jennifer K Chow
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
    Crit Care Med 36:1993-8. 2008
    ..To determine risk factors for bloodstream infections (BSI) with Candida non-albicans (C-NA) species and Candida albicans (CA) among critically ill patients...
  5. doi request reprint Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children: executive summary
    Catherine Liu
    Department of Medicine, Division of Infectious Diseases, University of California San Francisco, San Francisco, California 94102, USA
    Clin Infect Dis 52:285-92. 2011
    ..Recommendations are provided regarding vancomycin dosing and monitoring, management of infections due to MRSA strains with reduced susceptibility to vancomycin, and vancomycin treatment failures...
  6. pmc r-metHuLeptin improves highly active antiretroviral therapy-induced lipoatrophy and the metabolic syndrome, but not through altering circulating IGF and IGF-binding protein levels: observational and interventional studies in humans
    Aoife M Brennan
    Division of Endocrinology, Diabetes, and Metabolism, Harvard Medical School, Beth Israel Deaconess Medical Center, E St 816, 330 Brookline Avenue, Boston, Massachusetts 02215, USA
    Eur J Endocrinol 160:173-6. 2009
    ....
  7. doi request reprint Initial low-dose gentamicin for Staphylococcus aureus bacteremia and endocarditis is nephrotoxic
    Sara E Cosgrove
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Clin Infect Dis 48:713-21. 2009
    ..This study evaluated the association between this practice and nephrotoxicity...
  8. doi request reprint Factors associated with candidemia caused by non-albicans Candida species versus Candida albicans in the intensive care unit
    Jennifer K Chow
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Clin Infect Dis 46:1206-13. 2008
    ..We examined factors associated with BSIs due to non-albicans Candida species, compared with C. albicans BSIs, in an ICU patient population...
  9. pmc Adherence to Mediterranean diet is favorably associated with metabolic parameters in HIV-positive patients with the highly active antiretroviral therapy-induced metabolic syndrome and lipodystrophy
    Sotiris Tsiodras
    Division of Infectious Diseases, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Metabolism 58:854-9. 2009
    ..Further clinical studies are needed to confirm our data in different populations and to explore the underlying mechanisms...
  10. doi request reprint Development of reduced vancomycin susceptibility in methicillin-susceptible Staphylococcus aureus
    Satish K Pillai
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Infect Dis 49:1169-74. 2009
    ..aureus (MSSA) clinical isolates. This isogenic series permitted us to determine whether the evolution of reduced vancomycin susceptibility in MSSA is similar to that seen in MRSA...
  11. pmc Leptin replacement improves postprandial glycemia and insulin sensitivity in human immunodeficiency virus-infected lipoatrophic men treated with pioglitazone: a pilot study
    Faidon Magkos
    Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Metabolism 60:1045-9. 2011
    ..Results from this pilot study should be confirmed in larger clinical trials...
  12. ncbi request reprint The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges
    Sara E Cosgrove
    Division of Infectious Diseases, Johns Hopkins Medical Institutions, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Infect Control Hosp Epidemiol 26:166-74. 2005
    ..To evaluate the impact of methicillin resistance in Staphylococcus aureus on mortality, length of hospitalization, and hospital charges...
  13. doi request reprint Knowledge, attitudes, and practices of US practitioners who provide pre-travel advice
    Laura Kogelman
    Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, MA, USA
    J Travel Med 21:104-14. 2014
    ....
  14. ncbi request reprint Epidemiological comparison of true methicillin-resistant and methicillin-susceptible coagulase-negative staphylococcal bacteremia at hospital admission
    Evelina Tacconelli
    Beth Israel Deaconess Medical Center and Division of Infectious Diseases, Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Infect Dis 37:644-9. 2003
    ....
  15. doi request reprint Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children
    Catherine Liu
    Department of Medicine, Division of Infectious Diseases, University of California San Francisco, San Francisco, California94102, USA
    Clin Infect Dis 52:e18-55. 2011
    ..Recommendations are provided regarding vancomycin dosing and monitoring, management of infections due to MRSA strains with reduced susceptibility to vancomycin, and vancomycin treatment failures...
  16. ncbi request reprint Circulating resistin levels are not associated with fat redistribution, insulin resistance, or metabolic profile in patients with the highly active antiretroviral therapy-induced metabolic syndrome
    Diana Barb
    Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Stoneman 816, Boston, Massachusetts 02215, USA
    J Clin Endocrinol Metab 90:5324-8. 2005
    ..The mechanisms underlying the development of the highly active antiretroviral therapy (HAART)-induced metabolic syndrome remain to be fully elucidated...
  17. ncbi request reprint Infections of intracardiac devices
    Adolf W Karchmer
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Kennedy 6, Boston, MA 02215, USA
    Infect Dis Clin North Am 16:477-505, xii. 2002
    ..This article reviews the epidemiology, microbiology, clinical presentation, and medical as well as surgical therapy of intracardiac device infections...
  18. ncbi request reprint Infections of intracardiac devices
    Adolf W Karchmer
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston
    Cardiol Clin 21:253-71, vii. 2003
    ..This article reviews the epidemiology, microbiology, clinical presentation, and medical as well as surgical therapy of intracardiac device infections...
  19. ncbi request reprint Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis
    Sara E Cosgrove
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts, USA
    Clin Infect Dis 36:53-9. 2003
    ..54-2.42; P<.001); significant heterogeneity was present. We explored the reasons for heterogeneity by means of subgroup analyses. MRSA bacteremia is associated with significantly higher mortality rate than is MSSA bacteremia...
  20. ncbi request reprint Preventing the influx of vancomycin-resistant enterococci into health care institutions, by use of a simple validated prediction rule
    Evelina Tacconelli
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Clin Infect Dis 39:964-70. 2004
    ..The goal of this study was to develop a validated prediction rule for identification of patients harboring vancomycin-resistant enterococci (VRE) at hospital admission...
  21. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 29-2004. A 75-year-old woman with acute onset of chest pain followed by fever
    Adolf W Karchmer
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center Boston, USA
    N Engl J Med 351:1240-8. 2004
  22. ncbi request reprint Detection of Staphylococcus aureus in peripheral blood stem cell cultures after sterilization of standard blood cultures
    Mitchell J Schwaber
    Department of Medicine, Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Clin Apher 18:37-9. 2003
    ..Cultures of apheresis product may be more sensitive to the presence of bacteremia than standard blood cultures, and they should guide clinical decisions when the bacteria isolated are potential pathogens or suggest clinical infection...
  23. doi request reprint International travel by persons with medical comorbidities: understanding risks and providing advice
    Natasha S Hochberg
    Department of Medicine, Boston University School of Medicine, Boston, MA Department of Epidemiology, Boston University School of Public Health, Boston, MA Electronic address
    Mayo Clin Proc 88:1231-40. 2013
    ..To describe the medical conditions, travel plans, counseling, and medications prescribed for high-risk international travelers...
  24. ncbi request reprint Improvement in highly active antiretroviral therapy-induced metabolic syndrome by treatment with pioglitazone but not with fenofibrate: a 2 x 2 factorial, randomized, double-blinded, placebo-controlled trial
    Alina Gavrila
    Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Clin Infect Dis 40:745-9. 2005
    ..We found that the administration of pioglitazone, but not fenofibrate, improved insulin resistance, blood pressure, and lipid profile over a 12-month period...
  25. ncbi request reprint Prosthetic joint infections
    Irene G Sia
    Division of Infectious Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Infect Dis Clin North Am 19:885-914. 2005
    ..If surgery is not possible, an alternative is long-term oral antimicrobial suppression to maintain a functioning prosthesis. Treatment must be individualized for a specific infection in a specific patient...
  26. ncbi request reprint A randomized and blinded multicenter trial of high-dose fluconazole plus placebo versus fluconazole plus amphotericin B as therapy for candidemia and its consequences in nonneutropenic subjects
    John H Rex
    Division of Infectious Diseases, University of Texas Medical School, Houston, TX 77030, USA
    Clin Infect Dis 36:1221-8. 2003
    ..02). In nonneutropenic subjects, the combination of fluconazole plus AmB was not antagonistic compared with fluconazole alone, and the combination trended toward improved success and more-rapid clearance from the bloodstream...
  27. ncbi request reprint Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy
    Carol L Addy
    Department of Internal Medicine, Endocrinology Hypertension Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Clin Endocrinol Metab 88:627-36. 2003
    ..Thus, adiponectin replacement may be a potential treatment option to ameliorate the metabolic changes observed in this patient population...
  28. ncbi request reprint Non-HACEK gram-negative bacillus endocarditis
    Susan Morpeth
    Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina 27710, USA
    Ann Intern Med 147:829-35. 2007
    ....
  29. ncbi request reprint Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus
    Vance G Fowler
    Duke University Medical Center, Durham, NC 27710, USA
    N Engl J Med 355:653-65. 2006
    ..Alternative therapies for Staphylococcus aureus bacteremia and endocarditis are needed...
  30. ncbi request reprint Cardiology patient page. Bacterial endocarditis: the disease, treatment, and prevention
    Christopher H Cabell
    Duke University School of Medicine and Duke Clinical Research Institute, Durham, NC, USA
    Circulation 107:e185-7. 2003
  31. ncbi request reprint Diagnosis and treatment of diabetic foot infections
    Benjamin A Lipsky
    Medical Service, Veterans Affairs Puget Sound Health Care System, and Division of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98108 9804, USA
    Clin Infect Dis 39:885-910. 2004
  32. ncbi request reprint Empirical fluconazole versus placebo for intensive care unit patients: a randomized trial
    Mindy G Schuster
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Ann Intern Med 149:83-90. 2008
    ..Invasive infection with Candida species is an important cause of morbidity and mortality in intensive care unit (ICU) patients. Optimal preventive strategies have not been clearly defined...