Research Topics
Genomes and GenesSpecies | Jae Hee KangSummaryAffiliation: Harvard University Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Plasma IGF-I levels and cognitive performance in older womenOlivia Okereke
Division of Aging, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, 3rd Floor, 181 Longwood Avenue, Boston, MA 02115, USA
Neurobiol Aging 28:135-42. 2007..Emerging biologic and epidemiologic evidence suggests benefits of insulin-like growth factor-I (IGF-I) in cognitive aging...- Postmenopausal hormone therapy, timing of initiation, APOE and cognitive declineJae H Kang
Channing Lab, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Neurobiol Aging 33:1129-37. 2012..Regardless of timing of initiation, HT may be associated with worse rates of decline in general cognition, especially among those with an APOE e4 allele... - Regular use of nonsteroidal anti-inflammatory drugs and cognitive function in aging womenJae Hee Kang
Channing Lab, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, MA 02115, USA
Neurology 60:1591-7. 2003..To examine the relationship of nonsteroidal anti-inflammatory drug (NSAID) use and cognitive decline in young-old women... - Fruit and vegetable consumption and cognitive decline in aging womenJae H Kang
Channing Lab, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Ann Neurol 57:713-20. 2005..05 unit; 95% confidence interval, 0.02, 0.09; p trend < 0.001). These mean differences were equivalent to those observed for women about 1 to 2 years apart in age... - A trial of B vitamins and cognitive function among women at high risk of cardiovascular diseaseJae Hee Kang
Channing Laboratory, Boston, MA 02115, USA
Am J Clin Nutr 88:1602-10. 2008..High homocysteine concentrations may be neurotoxic and contribute to cognitive decline in older persons... - Prospective study of plasma folate, vitamin B12, and cognitive function and declineJae Hee Kang
Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Boston, MA, USA
Epidemiology 17:650-7. 2006..The relation between B vitamins and cognitive decline is controversial. In this study, we explored the association of plasma folate and vitamin B12 with cognitive function measured approximately 10 years later... - A randomized trial of vitamin E supplementation and cognitive function in womenJae Hee Kang
Channing Laboratory, Boston, MA 02115, USA
Arch Intern Med 166:2462-8. 2006..Oxidative stress may play a key role in the development of cognitive impairment. Long-term supplementation with vitamin E, a strong antioxidant, may provide cognitive benefits... - Plasma carotenoids and tocopherols and cognitive function: a prospective studyJae Hee Kang
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Neurobiol Aging 29:1394-403. 2008..19, 0.09), and 0.04 units for total tocopherols (95% CI -0.10, 0.18). Individual antioxidants were not associated with cognition. Overall, total plasma carotenoids or tocopherols were not related to cognition in women... - Low dose aspirin and cognitive function in the women's health study cognitive cohortJae Hee Kang
Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
BMJ 334:987. 2007..To determine whether low dose aspirin protects women aged 65 or more against cognitive decline... - Prospective study of alcohol consumption and the risk of primary open-angle glaucomaJae H Kang
Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Ophthalmic Epidemiol 14:141-7. 2007..Alcohol intake reduces intraocular pressure, a risk factor for primary open-angle glaucoma (POAG). We investigated whether alcohol consumption is associated with a reduced risk of POAG... - Caffeine consumption and the risk of primary open-angle glaucoma: a prospective cohort studyJae Hee Kang
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
Invest Ophthalmol Vis Sci 49:1924-31. 2008..To investigate whether caffeine, which transiently increases intraocular pressure (IOP) is associated with the risk of primary open-angle glaucoma (POAG)... - Apolipoprotein E, cardiovascular disease and cognitive function in aging womenJae Hee Kang
Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
Neurobiol Aging 26:475-84. 2005..Thus, APOE genotypes strongly influenced cognitive function and decline; prevention of cardiovascular disease may limit these effects... - Antioxidant intake and primary open-angle glaucoma: a prospective studyJae H Kang
Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
Am J Epidemiol 158:337-46. 2003..97 (95% CI: 0.62, 1.52) for vitamin E, and 1.11 (95% CI: 0.82, 1.51) for vitamin A. In conclusion, the authors did not observe any strong associations between antioxidant consumption and the risk of primary open-angle glaucoma... - Prospective study of cigarette smoking and the risk of primary open-angle glaucomaJae H Kang
Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
Arch Ophthalmol 121:1762-8. 2003..To examine the association between cigarette smoking and incident primary open-angle glaucoma (POAG)... - Dietary fat consumption and primary open-angle glaucomaJae H Kang
Department of Epidemiology, Harvard School of Public Health, Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
Am J Clin Nutr 79:755-64. 2004..Prostaglandin F(2alpha) analogues are effective intraocular-pressure-lowering drugs. Dietary fatty acids affect endogenous prostaglandin F(2alpha) concentrations and may thus influence intraocular pressure... - Postmenopausal hormone therapy and risk of cognitive decline in community-dwelling aging womenJae H Kang
Channing Lab, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Neurology 63:101-7. 2004..However, questions remain, including the effect of longer duration or of hormone therapy initiated at younger ages... - Vitamin E, vitamin C, beta carotene, and cognitive function among women with or at risk of cardiovascular disease: The Women's Antioxidant and Cardiovascular StudyJae Hee Kang
Harvard School of Public Health, Boston, Mass, USA
Circulation 119:2772-80. 2009..Cardiovascular factors are associated with cognitive decline. Antioxidants may be beneficial... - Dietary fat intake and cognitive decline in women with type 2 diabetesELIZABETH E DEVORE
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Diabetes Care 32:635-40. 2009..We investigated whether dietary fat, which modulates glucose and lipid metabolism, might influence cognitive decline in older adults with diabetes... - Prospective study of type 2 diabetes mellitus and risk of primary open-angle glaucoma in womenLouis R Pasquale
Glaucoma Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
Ophthalmology 113:1081-6. 2006..To study the relation between type 2 diabetes mellitus (T2DM) and incident primary open-angle glaucoma (POAG) in women... - Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with hypertension, alcohol intake, and cigarette smokingJae Hee Kang
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Arch Ophthalmol 129:773-80. 2011..To evaluate whether an association between risk of any of the factors of hypertension, alcohol intake, and cigarette smoking and the risk of primary open-angle glaucoma (POAG) depended on nitric oxide synthase 3 (NOS3) gene variants... - Effects of moderate alcohol consumption on cognitive function in womenMeir J Stampfer
Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA
N Engl J Med 352:245-53. 2005..g., wine or beer) and no interaction with the apolipoprotein E genotype. CONCLUSIONS: Our data suggest that in women, up to one drink per day does not impair cognitive function and may actually decrease the risk of cognitive decline... - Dietary intakes of berries and flavonoids in relation to cognitive declineELIZABETH E DEVORE
Channing Laboratory, Brigham and Women s Hospital, Boston, MA, USA
Ann Neurol 72:135-43. 2012..We prospectively evaluated whether greater long-term intakes of berries and flavonoids are associated with slower rates of cognitive decline in older women... - Total antioxidant capacity of diet in relation to cognitive function and declineELIZABETH E DEVORE
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Am J Clin Nutr 92:1157-64. 2010..Epidemiologic evidence on the association of individual antioxidant vitamins and cognition is inconsistent... - Physical activity levels and cognition in women with type 2 diabetesELIZABETH E DEVORE
Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Am J Epidemiol 170:1040-7. 2009..Results were similar for cognitive decline. These findings indicate little overall association between physical activity and cognition after adjustment for disability factors in older women with type 2 diabetes... - Attributes of female reproductive aging and their relation to primary open-angle glaucoma: a prospective studyLouis R Pasquale
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
J Glaucoma 16:598-605. 2007..We investigated the relation between age at menopause, postmenopausal hormone (PMH) use, and incident primary open-angle glaucoma (POAG)... - Lifestyle, nutrition, and glaucomaLouis R Pasquale
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
J Glaucoma 18:423-8. 2009..This review also outlines future directions for research into the primary prevention of POAG... - Reproductive factors and NOS3 variant interactions in primary open-angle glaucomaJae Hee Kang
Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
Mol Vis 17:2544-51. 2011..To investigate whether associations with the nitric oxide synthase gene (NOS3) variants and risk of primary open-angle glaucoma (POAG) depend on female reproductive factors... - Anthropometric measures and their relation to incident primary open-angle glaucomaLouis R Pasquale
Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
Ophthalmology 117:1521-9. 2010..To assess the relation between anthropometric measures and incident primary open-angle glaucoma (POAG)... - Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with sex and postmenopausal hormone useJae Hee Kang
Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
Invest Ophthalmol Vis Sci 51:971-9. 2010..To evaluate the association between the nitric oxide synthase gene (NOS3) variants and primary open-angle glaucoma (POAG)... - A prospective study of aspirin use and the risk of pancreatic cancer in womenEva S Schernhammer
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
J Natl Cancer Inst 96:22-8. 2004.... - Demographic and geographic features of exfoliation glaucoma in 2 United States-based prospective cohortsJae Hee Kang
Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
Ophthalmology 119:27-35. 2012..To examine prospectively the association between demographic and geographic factors in relation to exfoliation glaucoma (EG) or exfoliation glaucoma suspect (EGS)... - The relation between moderate alcohol consumption and cognitive function in older women with type 2 diabetesMary K Townsend
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
Diabetes Res Clin Pract 85:322-7. 2009..To examine the association between moderate drinking, cognitive function, and cognitive decline in women with type 2 diabetes... - Antioxidant intake and risks of rheumatoid arthritis and systemic lupus erythematosus in womenKaren H Costenbader
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Epidemiol 172:205-16. 2010..In these large, prospective cohorts of women, antioxidant intake was not associated with the risk of developing either rheumatoid arthritis or systemic lupus erythematosus... - Physical activity, including walking, and cognitive function in older womenJennifer Weuve
Department of Epidemiology, Harvard School of Public Health, Boston, Mass 02215, USA
JAMA 292:1454-61. 2004..Physical activity may help maintain cognitive function in older adults... - Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USAJaney L Wiggs
Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
Hum Mol Genet 20:4707-13. 2011..We also present data suggesting that associations with several CAV1/CAV2 SNPs are significant mostly in women... - Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 yearsGiancarlo Logroscino
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
BMJ 328:548. 2004..To examine the association of type 2 diabetes with baseline cognitive function and cognitive decline over two years of follow up, focusing on women living in the community and on the effects of treatments for diabetes... - Physical activity and cognition in women with vascular conditionsMarie Noël Vercambre
Foundation of Public Health, Mutuelle Generale de l Education Nationale, Paris, France
Arch Intern Med 171:1244-50. 2011..Individuals with vascular disease or risk factors have substantially higher rates of cognitive decline, yet little is known about means of maintaining cognition in this group... - Fasting insulin levels and cognitive decline in older women without diabetesMarieke van Oijen
Department of Epidemiology Biostatistics and Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
Neuroepidemiology 30:174-9. 2008..Type 2 diabetes has been associated with an increased risk of dementia. To assess possible independent effects of insulin, we investigated the relation of insulin levels to cognitive decline in nondiabetic women... - Sentinel lymph node biopsy after neoadjuvant chemotherapySeok Hyung Kang
National Cancer Center, Madu 1 dong 809, san gu, Goyang si, Gyeonggi Do, 411 769, Korea
Breast Cancer 11:233-41; discussion 264-6. 2004....
Research Grants
- Plasma Markers of Dietry Intervention to Delay Cognitiv*JAE KANG; Fiscal Year: 2005..Importantly, results from the proposed grant will lay the groundwork for a future, large-scale comprehensive study to examine dietary interventions to delay cognitive function. ..
- A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive DeclineJae H Kang; Fiscal Year: 2010....