Jae Hee Kang

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Plasma IGF-I levels and cognitive performance in older women
    Olivia Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, 3rd Floor, 181 Longwood Avenue, Boston, MA 02115, USA
    Neurobiol Aging 28:135-42. 2007
  2. pmc A nested case control study of plasma ICAM-1, E-selectin and TNF receptor 2 levels, and incident primary open-angle glaucoma
    Jae H Kang
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Invest Ophthalmol Vis Sci 54:1797-804. 2013
  3. pmc Postmenopausal hormone therapy, timing of initiation, APOE and cognitive decline
    Jae H Kang
    Channing Lab, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Neurobiol Aging 33:1129-37. 2012
  4. ncbi request reprint Prospective study of plasma folate, vitamin B12, and cognitive function and decline
    Jae Hee Kang
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Boston, MA, USA
    Epidemiology 17:650-7. 2006
  5. ncbi request reprint A randomized trial of vitamin E supplementation and cognitive function in women
    Jae Hee Kang
    Channing Laboratory, Boston, MA 02115, USA
    Arch Intern Med 166:2462-8. 2006
  6. pmc Plasma carotenoids and tocopherols and cognitive function: a prospective study
    Jae Hee Kang
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Neurobiol Aging 29:1394-403. 2008
  7. pmc Low dose aspirin and cognitive function in the women's health study cognitive cohort
    Jae Hee Kang
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    BMJ 334:987. 2007
  8. ncbi request reprint Prospective study of alcohol consumption and the risk of primary open-angle glaucoma
    Jae H Kang
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Ophthalmic Epidemiol 14:141-7. 2007
  9. pmc Caffeine consumption and the risk of primary open-angle glaucoma: a prospective cohort study
    Jae Hee Kang
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Invest Ophthalmol Vis Sci 49:1924-31. 2008
  10. pmc A trial of B vitamins and cognitive function among women at high risk of cardiovascular disease
    Jae Hee Kang
    Channing Laboratory, Boston, MA 02115, USA
    Am J Clin Nutr 88:1602-10. 2008

Detail Information

Publications40

  1. ncbi request reprint Plasma IGF-I levels and cognitive performance in older women
    Olivia Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, 3rd Floor, 181 Longwood Avenue, Boston, MA 02115, USA
    Neurobiol Aging 28:135-42. 2007
    ..Emerging biologic and epidemiologic evidence suggests benefits of insulin-like growth factor-I (IGF-I) in cognitive aging...
  2. pmc A nested case control study of plasma ICAM-1, E-selectin and TNF receptor 2 levels, and incident primary open-angle glaucoma
    Jae H Kang
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Invest Ophthalmol Vis Sci 54:1797-804. 2013
    ..To evaluate prediagnostic markers of endothelial dysfunction and inflammatory processes in primary open-angle glaucoma (POAG)...
  3. pmc Postmenopausal hormone therapy, timing of initiation, APOE and cognitive decline
    Jae H Kang
    Channing Lab, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Neurobiol Aging 33:1129-37. 2012
    ..Regardless of timing of initiation, HT may be associated with worse rates of decline in general cognition, especially among those with an APOE e4 allele...
  4. ncbi request reprint Prospective study of plasma folate, vitamin B12, and cognitive function and decline
    Jae Hee Kang
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Boston, MA, USA
    Epidemiology 17:650-7. 2006
    ..The relation between B vitamins and cognitive decline is controversial. In this study, we explored the association of plasma folate and vitamin B12 with cognitive function measured approximately 10 years later...
  5. ncbi request reprint A randomized trial of vitamin E supplementation and cognitive function in women
    Jae Hee Kang
    Channing Laboratory, Boston, MA 02115, USA
    Arch Intern Med 166:2462-8. 2006
    ..Oxidative stress may play a key role in the development of cognitive impairment. Long-term supplementation with vitamin E, a strong antioxidant, may provide cognitive benefits...
  6. pmc Plasma carotenoids and tocopherols and cognitive function: a prospective study
    Jae Hee Kang
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Neurobiol Aging 29:1394-403. 2008
    ..19, 0.09), and 0.04 units for total tocopherols (95% CI -0.10, 0.18). Individual antioxidants were not associated with cognition. Overall, total plasma carotenoids or tocopherols were not related to cognition in women...
  7. pmc Low dose aspirin and cognitive function in the women's health study cognitive cohort
    Jae Hee Kang
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    BMJ 334:987. 2007
    ..To determine whether low dose aspirin protects women aged 65 or more against cognitive decline...
  8. ncbi request reprint Prospective study of alcohol consumption and the risk of primary open-angle glaucoma
    Jae H Kang
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Ophthalmic Epidemiol 14:141-7. 2007
    ..Alcohol intake reduces intraocular pressure, a risk factor for primary open-angle glaucoma (POAG). We investigated whether alcohol consumption is associated with a reduced risk of POAG...
  9. pmc Caffeine consumption and the risk of primary open-angle glaucoma: a prospective cohort study
    Jae Hee Kang
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Invest Ophthalmol Vis Sci 49:1924-31. 2008
    ..To investigate whether caffeine, which transiently increases intraocular pressure (IOP) is associated with the risk of primary open-angle glaucoma (POAG)...
  10. pmc A trial of B vitamins and cognitive function among women at high risk of cardiovascular disease
    Jae Hee Kang
    Channing Laboratory, Boston, MA 02115, USA
    Am J Clin Nutr 88:1602-10. 2008
    ..High homocysteine concentrations may be neurotoxic and contribute to cognitive decline in older persons...
  11. pmc Vitamin E, vitamin C, beta carotene, and cognitive function among women with or at risk of cardiovascular disease: The Women's Antioxidant and Cardiovascular Study
    Jae Hee Kang
    Harvard School of Public Health, Boston, Mass, USA
    Circulation 119:2772-80. 2009
    ..Cardiovascular factors are associated with cognitive decline. Antioxidants may be beneficial...
  12. ncbi request reprint Fruit and vegetable consumption and cognitive decline in aging women
    Jae H Kang
    Channing Lab, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Ann Neurol 57:713-20. 2005
    ..05 unit; 95% confidence interval, 0.02, 0.09; p trend < 0.001). These mean differences were equivalent to those observed for women about 1 to 2 years apart in age...
  13. ncbi request reprint Regular use of nonsteroidal anti-inflammatory drugs and cognitive function in aging women
    Jae Hee Kang
    Channing Lab, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, MA 02115, USA
    Neurology 60:1591-7. 2003
    ..To examine the relationship of nonsteroidal anti-inflammatory drug (NSAID) use and cognitive decline in young-old women...
  14. ncbi request reprint Prospective study of cigarette smoking and the risk of primary open-angle glaucoma
    Jae H Kang
    Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
    Arch Ophthalmol 121:1762-8. 2003
    ..To examine the association between cigarette smoking and incident primary open-angle glaucoma (POAG)...
  15. ncbi request reprint Dietary fat consumption and primary open-angle glaucoma
    Jae H Kang
    Department of Epidemiology, Harvard School of Public Health, Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Clin Nutr 79:755-64. 2004
    ..Prostaglandin F(2alpha) analogues are effective intraocular-pressure-lowering drugs. Dietary fatty acids affect endogenous prostaglandin F(2alpha) concentrations and may thus influence intraocular pressure...
  16. ncbi request reprint Apolipoprotein E, cardiovascular disease and cognitive function in aging women
    Jae Hee Kang
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Neurobiol Aging 26:475-84. 2005
    ..Thus, APOE genotypes strongly influenced cognitive function and decline; prevention of cardiovascular disease may limit these effects...
  17. ncbi request reprint Antioxidant intake and primary open-angle glaucoma: a prospective study
    Jae H Kang
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Epidemiol 158:337-46. 2003
    ..97 (95% CI: 0.62, 1.52) for vitamin E, and 1.11 (95% CI: 0.82, 1.51) for vitamin A. In conclusion, the authors did not observe any strong associations between antioxidant consumption and the risk of primary open-angle glaucoma...
  18. ncbi request reprint Postmenopausal hormone therapy and risk of cognitive decline in community-dwelling aging women
    Jae H Kang
    Channing Lab, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Neurology 63:101-7. 2004
    ..However, questions remain, including the effect of longer duration or of hormone therapy initiated at younger ages...
  19. pmc Dietary fat intake and cognitive decline in women with type 2 diabetes
    ELIZABETH E DEVORE
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Diabetes Care 32:635-40. 2009
    ..We investigated whether dietary fat, which modulates glucose and lipid metabolism, might influence cognitive decline in older adults with diabetes...
  20. ncbi request reprint Prospective study of type 2 diabetes mellitus and risk of primary open-angle glaucoma in women
    Louis R Pasquale
    Glaucoma Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthalmology 113:1081-6. 2006
    ..To study the relation between type 2 diabetes mellitus (T2DM) and incident primary open-angle glaucoma (POAG) in women...
  21. pmc Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with hypertension, alcohol intake, and cigarette smoking
    Jae Hee Kang
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Arch Ophthalmol 129:773-80. 2011
    ..To evaluate whether an association between risk of any of the factors of hypertension, alcohol intake, and cigarette smoking and the risk of primary open-angle glaucoma (POAG) depended on nitric oxide synthase 3 (NOS3) gene variants...
  22. ncbi request reprint Effects of moderate alcohol consumption on cognitive function in women
    Meir J Stampfer
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
    N Engl J Med 352:245-53. 2005
    ..The adverse effects of excess alcohol intake on cognitive function are well established, but the effect of moderate consumption is uncertain...
  23. pmc Dietary intakes of berries and flavonoids in relation to cognitive decline
    ELIZABETH E DEVORE
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA, USA
    Ann Neurol 72:135-43. 2012
    ..We prospectively evaluated whether greater long-term intakes of berries and flavonoids are associated with slower rates of cognitive decline in older women...
  24. pmc Total antioxidant capacity of diet in relation to cognitive function and decline
    ELIZABETH E DEVORE
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 92:1157-64. 2010
    ..Epidemiologic evidence on the association of individual antioxidant vitamins and cognition is inconsistent...
  25. pmc Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with sex and postmenopausal hormone use
    Jae Hee Kang
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 51:971-9. 2010
    ..To evaluate the association between the nitric oxide synthase gene (NOS3) variants and primary open-angle glaucoma (POAG)...
  26. pmc Physical activity levels and cognition in women with type 2 diabetes
    ELIZABETH E DEVORE
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Am J Epidemiol 170:1040-7. 2009
    ..Results were similar for cognitive decline. These findings indicate little overall association between physical activity and cognition after adjustment for disability factors in older women with type 2 diabetes...
  27. pmc Lifestyle, nutrition, and glaucoma
    Louis R Pasquale
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    J Glaucoma 18:423-8. 2009
    ..This review also outlines future directions for research into the primary prevention of POAG...
  28. ncbi request reprint Attributes of female reproductive aging and their relation to primary open-angle glaucoma: a prospective study
    Louis R Pasquale
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    J Glaucoma 16:598-605. 2007
    ..We investigated the relation between age at menopause, postmenopausal hormone (PMH) use, and incident primary open-angle glaucoma (POAG)...
  29. pmc Reproductive factors and NOS3 variant interactions in primary open-angle glaucoma
    Jae Hee Kang
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
    Mol Vis 17:2544-51. 2011
    ..To investigate whether associations with the nitric oxide synthase gene (NOS3) variants and risk of primary open-angle glaucoma (POAG) depend on female reproductive factors...
  30. ncbi request reprint A prospective study of aspirin use and the risk of pancreatic cancer in women
    Eva S Schernhammer
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Natl Cancer Inst 96:22-8. 2004
    ....
  31. pmc Anthropometric measures and their relation to incident primary open-angle glaucoma
    Louis R Pasquale
    Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthalmology 117:1521-9. 2010
    ..To assess the relation between anthropometric measures and incident primary open-angle glaucoma (POAG)...
  32. pmc Demographic and geographic features of exfoliation glaucoma in 2 United States-based prospective cohorts
    Jae Hee Kang
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts, USA
    Ophthalmology 119:27-35. 2012
    ..To examine prospectively the association between demographic and geographic factors in relation to exfoliation glaucoma (EG) or exfoliation glaucoma suspect (EGS)...
  33. pmc The relation between moderate alcohol consumption and cognitive function in older women with type 2 diabetes
    Mary K Townsend
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Diabetes Res Clin Pract 85:322-7. 2009
    ..To examine the association between moderate drinking, cognitive function, and cognitive decline in women with type 2 diabetes...
  34. pmc Antioxidant intake and risks of rheumatoid arthritis and systemic lupus erythematosus in women
    Karen H Costenbader
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Epidemiol 172:205-16. 2010
    ..In these large, prospective cohorts of women, antioxidant intake was not associated with the risk of developing either rheumatoid arthritis or systemic lupus erythematosus...
  35. ncbi request reprint Physical activity, including walking, and cognitive function in older women
    Jennifer Weuve
    Department of Epidemiology, Harvard School of Public Health, Boston, Mass 02215, USA
    JAMA 292:1454-61. 2004
    ..Physical activity may help maintain cognitive function in older adults...
  36. pmc Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA
    Janey L Wiggs
    Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Hum Mol Genet 20:4707-13. 2011
    ..We also present data suggesting that associations with several CAV1/CAV2 SNPs are significant mostly in women...
  37. pmc Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years
    Giancarlo Logroscino
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    BMJ 328:548. 2004
    ..To examine the association of type 2 diabetes with baseline cognitive function and cognitive decline over two years of follow up, focusing on women living in the community and on the effects of treatments for diabetes...
  38. pmc Physical activity and cognition in women with vascular conditions
    Marie Noël Vercambre
    Foundation of Public Health, Mutuelle Generale de l Education Nationale, Paris, France
    Arch Intern Med 171:1244-50. 2011
    ..Individuals with vascular disease or risk factors have substantially higher rates of cognitive decline, yet little is known about means of maintaining cognition in this group...
  39. pmc Fasting insulin levels and cognitive decline in older women without diabetes
    Marieke van Oijen
    Department of Epidemiology Biostatistics and Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Neuroepidemiology 30:174-9. 2008
    ..Type 2 diabetes has been associated with an increased risk of dementia. To assess possible independent effects of insulin, we investigated the relation of insulin levels to cognitive decline in nondiabetic women...
  40. ncbi request reprint Sentinel lymph node biopsy after neoadjuvant chemotherapy
    Seok Hyung Kang
    National Cancer Center, Madu 1 dong 809, san gu, Goyang si, Gyeonggi Do, 411 769, Korea
    Breast Cancer 11:233-41; discussion 264-6. 2004
    ....

Research Grants2

  1. Plasma Markers of Dietry Intervention to Delay Cognitiv*
    JAE KANG; Fiscal Year: 2005
    ..Importantly, results from the proposed grant will lay the groundwork for a future, large-scale comprehensive study to examine dietary interventions to delay cognitive function. ..
  2. A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive Decline
    Jae H Kang; Fiscal Year: 2010
    ....