Affiliation: Harvard University
- Phosphorylated hMSH6: DNA mismatch versus DNA damage recognitionSaravanan Kaliyaperumal
Department of Biochemistry and Cancer Biology, University of Toledo College of Medicine, Toledo, OH 43614, USA
Mutat Res 706:36-45. 2011..We hypothesize that both phosphorylation of hMSH6 and total concentration of bound hMutSα are involved in cellular signaling of either DNA mismatch repair or MMR-dependent damage recognition activities...
- Prolonged cell cycle response of HeLa cells to low-level alkylation exposureAllen G Schroering
Department of Biochemistry and Cancer Biology, University of Toledo College of Medicine, Toledo, Ohio 43614, USA
Cancer Res 69:6307-14. 2009..This information should prove clinically relevant for the future design of enhanced cancer chemotherapeutics...
- The ATPase motif in RAD51D is required for resistance to DNA interstrand crosslinking agents and interaction with RAD51CAaron M Gruver
Department of Physiology and Cardiovascular Genomics, Medical University of Ohio, Toledo, OH 43614 5804, USA
Mutagenesis 20:433-40. 2005..These cell-based studies are the first evidence that ATP binding and hydrolysis by RAD51D are required for efficient HR repair of DNA interstrand crosslinks...