Research Topics
| L B KabanSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Biomedical technology revolution: opportunities and challenges for oral and maxillofacial surgeonsL B Kaban
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston 02114, USA
Int J Oral Maxillofac Surg 31:1-12. 2002....- Antiangiogenic therapy with interferon alpha for giant cell lesions of the jawsLeonard B Kaban
Walter C Guralnick Professor and Chairman, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine, Boston 02114, USA
J Oral Maxillofac Surg 60:1103-11; discussion 1111-3. 2002..The purpose of this report is to present a treatment protocol consisting of enucleation, with preservation of vital structures, followed by subcutaneous interferon alpha... - Correlation of biomechanical stiffness with plain radiographic and ultrasound data in an experimental mandibular distraction woundL B Kaban
The Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine, Boston, MA, USA
Int J Oral Maxillofac Surg 32:296-304. 2003..This may have implications for the management of patients who undergo large movements by distraction... - Assessment of bone formation in a porcine mandibular distraction wound by computed tomographyC E Zimmermann
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine and Harvard Medical School, Boston, MA 02114, USA
Int J Oral Maxillofac Surg 33:569-74. 2004..3%). The results of this study indicate that despite high bone fill scores on plain radiographs, the highest percent CT bone volume achieved in this model was 64%... - Histology of the porcine mandibular distraction woundC E Zimmermann
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston, MA 02114, USA
Int J Oral Maxillofac Surg 34:411-9. 2005..New bone formed by intramembranous ossification alone. The results of this experiment document the contribution of endosteal bone formation in this model of distraction osteogenesis... - Proliferation of masseter myocytes after distraction osteogenesis of the porcine mandibleF J Castaño
Skeletal Biology Research Center and Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston 02129, USA
J Oral Maxillofac Surg 59:302-7. 2001..The hypothesis tested in this study was that mandibular elongation by distraction induces myocyte proliferation... 
BMP4 localization and PCNA expression during distraction osteogenesis of the porcine mandibleG M Hansen
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston, MA, USA
Int J Oral Maxillofac Surg 41:867-73. 2012..Progenitor cell proliferation and BMP4 expression are greatest during mid-DO and decrease progressively thereafter. At the time of death of the acute lengthening group, only increased cell proliferation was demonstrated...
Osteomark: a surgical navigation system for oral and maxillofacial surgeryC Bouchard
The Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston, MA, USA
Int J Oral Maxillofac Surg 41:265-70. 2012..Osteomark was simple to use and permitted localisation of holes and osteotomies with acceptable accuracy. In the future, the device and algorithms will be revised to further decrease error and the system will be tested on live animals...- Nicotine impairs distraction osteogenesis in the rat mandibleJ Glowacki
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA, USA
Int J Oral Maxillofac Surg 37:156-61. 2008..0008). Histological analysis demonstrated less bone, vascularity and cellular activity in nicotine-treated rats. This study shows that nicotine reproducibly inhibits osteogenesis, vascularity and bone lengthening in mandibular DO... - Endoscopic approach to the ramus/condyle unit: Clinical applicationsM J Troulis
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Warren Building 1201, 55 Fruit St, Boston, MA 02114, USA
J Oral Maxillofac Surg 59:503-9. 2001..The purpose of this report is to describe use of an endoscopic technique for exposure of the mandibular ramus/condyle unit (RCU) to facilitate reconstructive jaw procedures... - Evaluation of a semiburied, fixed-trajectory, curvilinear, distraction device in an animal modelE B Seldin
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine, Boston 02114, USA
J Oral Maxillofac Surg 57:1442-6; discussion 1447-8. 1999..The geometrical basis for such devices and the 3-dimensional treatment planning system required to make buried distractors practical are discussed... - IGF-I, TGF-beta, and BMP-4 are expressed during distraction osteogenesis of the pig mandibleK E Yates
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, USA
Int J Oral Maxillofac Surg 31:173-8. 2002..As the pig mandible closely resembles that of the human in morphology and physiology, this is an important step toward characterization of the early molecular events in the DO wound... - A protocol for the management of failed alloplastic temporomandibular joint disc implantsG J Kearns
Department of Oral and Maxillofacial Surgery, University of California, San Francisco 94143 0440, USA
J Oral Maxillofac Surg 53:1240-7; discussion 1248-9. 1995..This is a retrospective evaluation of a protocol for management of failed alloplastic temporomandibular joint (TMJ) disc implants... - Development of a three-dimensional treatment planning system based on computed tomographic dataM J Troulis
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston 02114, USA
Int J Oral Maxillofac Surg 31:349-57. 2002..Software demonstrated here will allow the surgeon to accurately plan treatment and evaluate craniomaxillofacial surgery outcomes. Future applications may include surgical navigation... - Replication of ancient Egyptian osteotomies of the facial skeleton: insights into the mummification processZ S Peacock
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Int J Oral Maxillofac Surg 40:1301-6. 2011..Results of this study demonstrate that the ancient skeletal mutilations could have been performed transorally during the mummification process and would have enhanced jaw opening... - Simultaneous maxillary and mandibular distraction osteogenesis with a semiburied deviceB L Padwa
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Children s Hospital and Harvard School of Dental Medicine, Boston 02115, USA
Int J Oral Maxillofac Surg 28:2-8. 1999..The indications for bimaxillary distraction are reviewed, including its advantages, disadvantages and limitations... - Pediatric facial fractures: recent advances in prevention, diagnosis and managementC E Zimmermann
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston 02114, USA
Int J Oral Maxillofac Surg 35:2-13. 2006..Children require long-term follow-up to monitor potential growth abnormalities. This article is a review of the epidemiology, diagnosis and management of facial fractures in children... - Isolated microtia as a marker for unsuspected hemifacial microsomiaIvan J Keogh
Department of Otolaryngology, Pediatric Otolaryngology Service, Massachusetts Eye and Ear Infirmary, and Department of Genetics, Harvard Medical School, Boston, MA, USA
Arch Otolaryngol Head Neck Surg 133:997-1001. 2007..To determine the proportion of hemifacial microsomia (HFM) in patients with unilateral or bilateral "isolated" microtia... - A financial analysis of maxillomandibular fixation versus rigid internal fixation for treatment of mandibular fracturesB L Schmidt
Department of Oral and Maxillofacial Surgery, University of California, San Francisco, USA
J Oral Maxillofac Surg 58:1206-10; discussion 1210-1. 2000..The aim of this study was to compare the cost-effectiveness of mandibular fracture treatment by closed reduction with maxillomandibular fixation (CRF) with open reduction and rigid internal fixation (ORIF)... - Fine-needle aspiration biopsy of intraosseous jaw lesionsM August
Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston 02114, USA
J Oral Maxillofac Surg 57:1282-6; discussion 1287. 1999..This study assessed diagnostic accuracy, determined reasons for error, and evaluated modifications to improve the reliability of fine-needle aspiration biopsy (FNAB) of primary jaw lesions... - Endoscopic approach for mandibular orthognathic surgeryMaria J Troulis
Massachusetts General Hospital, Warren Building, Suite 1201, Boston MA 02114, USA
Facial Plast Surg Clin North Am 14:45-50. 2006..This article describes the history of surgery and newer developments in endoscopic surgery for mandibular orthognathic surgery... - Adjuvant antiangiogenic therapy for giant cell tumors of the jawsLeonard B Kaban
Department of Oral and Maxillofacial Surgery, Harvard School of Dental Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
J Oral Maxillofac Surg 65:2018-24; discussion 2024. 2007..To further evaluate a novel treatment protocol for the management of aggressive giant cell lesions (GCLs) consisting of enucleation followed by adjuvant subcutaneous interferon alpha therapy... - Range of curvilinear distraction devices required for treatment of mandibular deformitiesLutz Ritter
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA, USA
J Oral Maxillofac Surg 64:259-64. 2006..8 mm of error. CONCLUSIONS: The results of this study indicate that a family of 5 curvilinear distractors may suffice to treat a broad range of mandibular deformities... - Microscopic changes in the condyle and disc in response to distraction osteogenesis of the minipig mandiblePetra Thurmüller
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, and Harvard Medical School, Boston, MA 02114, USA
J Oral Maxillofac Surg 64:249-58. 2006..The purpose of this study was to correlate histologic findings with these gross changes in a minipig distraction model... - Mandibular advancement by distraction osteogenesis for tracheostomy-dependent children with severe micrognathiaDerek M Steinbacher
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA 02112, USA
J Oral Maxillofac Surg 63:1072-9. 2005..CONCLUSIONS: The results of this preliminary study indicate that mandibular advancement by DO is a potentially viable treatment option for tracheostomy-dependent children with upper airway obstruction secondary to micrognathia... - A computer-assisted approach to planning multidimensional distraction osteogenesisKrishna C Yeshwant
Harvard Medical School, Boston, MA, USA
Atlas Oral Maxillofac Surg Clin North Am 13:1-12. 2005 - Changes in the condyle and disc in response to distraction osteogenesis of the minipig mandiblePetra Thurmüller
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine and Harvard Medical School, Boston, MA 02114, USA
J Oral Maxillofac Surg 60:1327-33. 2002..The purpose of this study was to evaluate the effect of DO, at varying rates, on the mandibular condyle and articular disc... - Formation of a mandibular condyle in vitro by tissue engineeringHarutsugi Abukawa
Department of Oral and Maxillofacial Surgery-Massachusetts General Hospital and Harvard School of Dental Medicine, Boston, MA 02114, USA
J Oral Maxillofac Surg 61:94-100. 2003..03 mm. Bone was not observed in the control scaffolds. CONCLUSION: In this pilot study, autologous tissue-engineered bone constructs were successfully made by combining biodegradable polymers and pMSCs... - Ultrasound: assessment of the distraction osteogenesis wound in patients undergoing mandibular lengtheningMaria J Troulis
Minimally Invasive Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine and Harvard Medical School, Boston, MA 02114, USA
J Oral Maxillofac Surg 61:1144-9. 2003..It has proved to be useful for the evaluation of long bone DO healing. The purpose of this study was to determine the efficacy of US for evaluation of bone formation in the mandibular distraction wound... - Distraction osteogenesis of the porcine mandible: histomorphometric evaluation of boneJulie Glowacki
Skeletal Biology Research Center, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston, USA
Plast Reconstr Surg 113:566-73. 2004..These results are consistent with the authors' previously reported clinical and radiographic observations that a latency period is not necessary for successful healing of the mandibular distraction osteogenesis wound... - Staged protocol for resection, skeletal reconstruction, and oral rehabilitation of children with jaw tumorsMaria J Troulis
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston, MA 02114, USA
J Oral Maxillofac Surg 62:335-43. 2004..The purpose of this study was to evaluate a staged protocol for resection of jaw tumors and reconstruction including implants in pediatric patients... - Reconstruction of mandibular defects with autologous tissue-engineered boneHaru Abukawa
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston 02114, USA
J Oral Maxillofac Surg 62:601-6. 2004.... - Use of ultrasound to assess healing of a mandibular distraction woundPetra Thurmüller
Massachusetts General Hospital, Harvard School of Dental Medicine and Harvard Medical School, Boston 02114, USA
J Oral Maxillofac Surg 60:1038-44. 2002..The purpose of this study was to test the feasibility of ultrasound to evaluate an experimental mandibular distraction osteogenesis wound... - Endoscopic vertical ramus osteotomy: early clinical resultsMaria J Troulis
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston, MA 02114, USA
J Oral Maxillofac Surg 62:824-8. 2004..CONCLUSIONS: The results of this case series indicate that endoscopic vertical ramus osteotomy with rigid fixation is feasible for correction of a variety of mandibular deformities... - Analysis of skeletal movements in mandibular distraction osteogenesisKrishna Yeshwant
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston 02114, USA
J Oral Maxillofac Surg 63:335-40. 2005.... - Vascularized fibular graft for pediatric mandibular reconstructionLifei Guo
Harvard Combined Plastic Surgery Program, Children s Hospital of Boston, Boston, Mass, USA
Plast Reconstr Surg 121:2095-105. 2008..Although vascularized bone grafts have become well accepted in adults, especially following ablative head and neck procedures, there are few long-term reports of their use in pediatric patients... - Immunohistochemical evaluation of giant cell tumors of the jaws using CD34 density analysisNathan C Dewsnup
Harvard School of Dental Medicine, Boston, MA, USA
J Oral Maxillofac Surg 66:928-33. 2008..To compare CD34 expression in both aggressive and nonaggressive giant cell lesions of the jaws and identify any associations between tumor vascular density and biologic behavior... - Changing patterns of hospital length of stay after orthognathic surgeryEvelyn T Huamán
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital Boston, MA 02114, USA
J Oral Maxillofac Surg 66:492-7. 2008..The purpose of this study was to estimate the hospital length of stay (LOS) and identify factors associated with LOS in orthognathic surgery patients... - Condylectomy and costochondral graft reconstruction for treatment of active idiopathic condylar resorptionMaria J Troulis
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston, MA 02114, USA
J Oral Maxillofac Surg 66:65-72. 2008..The purpose of this study was to evaluate the outcomes in patients with active bilateral idiopathic condylar resorption treated by condylectomy and costochondral graft (CCG) reconstruction... - Anthropometric analysis of mandibular asymmetry in infants with deformational posterior plagiocephalyDane St John
Harvard School of Dental Medicine, Boston, MA, USA
J Oral Maxillofac Surg 60:873-7. 2002..We tested the hypothesis that mandibular asymmetry, associated with this condition, is secondary to anterior displacement of the ipsilateral temporomandibular joint. The response to molding helmet therapy was also evaluated... - Synovial chondromatosis of the temporomandibular joint: report and analysis of eleven casesLeon Ardekian
Rambam Medical Center, Haifa, Israel
J Oral Maxillofac Surg 63:941-7. 2005..In a subset of cases, fine needle aspiration is useful for confirming the clinicoradiographic impression. Complete removal of involved tissue is associated with an excellent prognosis... - Using ultrasound to visualize the lingual nerveJames Olsen
Oral and Maxillofacial Surgery, University of California Los Angeles, Los Angeles, CA, USA
J Oral Maxillofac Surg 65:2295-300. 2007..The purpose of this study was to assess the effectiveness of ultrasonography in visualizing the lingual nerve, calculating its distance from the lingual cortex at the area of the third molar, and in detecting injuries... - Toothache, paresthesia, and Horner syndrome: an unusual presentation of disseminated Burkitt's lymphomaMark Nissenbaum
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
J Oral Maxillofac Surg 65:1395-401. 2007 - Massachusetts General Hospital/Harvard Medical School MD oral and maxillofacial surgery program: a 30-year reviewThomas B Dodson
Department of Oral and Maxillofacial Surgery, Harvard School of Dental Medicine, and Director of Resident Training, Massachusetts General Hospital, Boston, MA 02114, USA
J Oral Maxillofac Surg 62:62-5. 2004..The purpose of this report is to provide a summary of the first 30 years of the program and to outline plans for its future... - The engineering of craniofacial tissues in the laboratory: a review of biomaterials for scaffolds and implant coatingsHaru Abukawa
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Dent Clin North Am 50:205-16, viii. 2006..The purpose of this article is to review advances in biomaterials, scaffolds, and implant coatings for craniomaxillofacial (bone) tissue engineering... - Endoscopic mandibular condylectomy and reconstruction: early clinical resultsMaria J Troulis
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston, MA, USA
J Oral Maxillofac Surg 62:460-5. 2004..CONCLUSION: The results of this study indicate that endoscopic condylectomy and CCG reconstruction produce satisfactory clinical outcomes without significant morbidity. Long-term follow-up studies are in progress... - Tissue-engineered hybrid tooth and boneConan S Young
Department of Cytokine Biology, Forsyth Institute, Boston, Massachusetts 02115, USA
Tissue Eng 11:1599-610. 2005..These results demonstrate the utility of a hybrid tooth-bone tissue-engineering approach for the eventual clinical treatment of tooth loss accompanied by alveolar bone resorption... - Massachusetts General Hospital/Harvard MD Oral and Maxillofacial Surgery ProgramLeonard B Kaban
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA 02112, USA
J Oral Maxillofac Surg 63:1069-72. 2005 - Effect of interferon-alpha-2b on porcine mesenchymal stem cellsHaru Abukawa
Skeletal Biology Research Center, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine, Boston, MA 02114, USA
J Oral Maxillofac Surg 64:1214-20. 2006..CONCLUSION: The data indicate that interferon may act to differentiate MSCs into osteoblasts and to stimulate metabolic activity while not increasing the proliferation rate...