Ula V Jurkunas

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Evidence of oxidative stress in the pathogenesis of fuchs endothelial corneal dystrophy
    Ula V Jurkunas
    Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    Am J Pathol 177:2278-89. 2010
  2. pmc Decreased expression of peroxiredoxins in Fuchs' endothelial dystrophy
    Ula V Jurkunas
    Schepens Eye Research Institute, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 49:2956-63. 2008
  3. pmc Increased clusterin expression in Fuchs' endothelial dystrophy
    Ula V Jurkunas
    Schepens Eye Research Institute, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 49:2946-55. 2008
  4. pmc Colocalization of increased transforming growth factor-beta-induced protein (TGFBIp) and Clusterin in Fuchs endothelial corneal dystrophy
    Ula V Jurkunas
    Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 50:1129-36. 2009
  5. pmc Decline in DJ-1 and decreased nuclear translocation of Nrf2 in Fuchs endothelial corneal dystrophy
    Maya S Bitar
    Schepens Eye Research Institute, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 53:5806-13. 2012
  6. pmc Telomerase immortalization of human corneal endothelial cells yields functional hexagonal monolayers
    Thore Schmedt
    Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 7:e51427. 2012
  7. pmc p53-regulated increase in oxidative-stress--induced apoptosis in Fuchs endothelial corneal dystrophy: a native tissue model
    Behrooz Azizi
    Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 52:9291-7. 2011
  8. doi request reprint Comparative analysis of human-derived feeder layers with 3T3 fibroblasts for the ex vivo expansion of human limbal and oral epithelium
    Sandhya M Sharma
    Schepens Eye Research Institute, 20 Staniford Street, Boston, MA 02114, USA
    Stem Cell Rev 8:696-705. 2012
  9. pmc Inflammation and the nervous system: the connection in the cornea in patients with infectious keratitis
    Andrea Cruzat
    Ocular Surface Imaging Center, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 52:5136-43. 2011
  10. pmc Unusual presentation of presumed posterior polymorphous dystrophy associated with iris heterochromia, band keratopathy, and keratoconus
    Helene Y Lam
    Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    Cornea 29:1180-5. 2010

Collaborators

Detail Information

Publications14

  1. pmc Evidence of oxidative stress in the pathogenesis of fuchs endothelial corneal dystrophy
    Ula V Jurkunas
    Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    Am J Pathol 177:2278-89. 2010
    ..This study provides evidence that oxidative stress plays a key role in FECD pathogenesis...
  2. pmc Decreased expression of peroxiredoxins in Fuchs' endothelial dystrophy
    Ula V Jurkunas
    Schepens Eye Research Institute, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 49:2956-63. 2008
    ....
  3. pmc Increased clusterin expression in Fuchs' endothelial dystrophy
    Ula V Jurkunas
    Schepens Eye Research Institute, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 49:2946-55. 2008
    ..To investigate the differential expression of the glycoprotein clusterin/apoJ (CLU) in normal and Fuchs' endothelial dystrophy (FED) corneal endothelium and to compare the expression of various forms of CLU in normal and FED tissue...
  4. pmc Colocalization of increased transforming growth factor-beta-induced protein (TGFBIp) and Clusterin in Fuchs endothelial corneal dystrophy
    Ula V Jurkunas
    Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 50:1129-36. 2009
    ....
  5. pmc Decline in DJ-1 and decreased nuclear translocation of Nrf2 in Fuchs endothelial corneal dystrophy
    Maya S Bitar
    Schepens Eye Research Institute, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 53:5806-13. 2012
    ....
  6. pmc Telomerase immortalization of human corneal endothelial cells yields functional hexagonal monolayers
    Thore Schmedt
    Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 7:e51427. 2012
    ..This study will significantly impact the fields of corneal cell biology and regenerative medicine...
  7. pmc p53-regulated increase in oxidative-stress--induced apoptosis in Fuchs endothelial corneal dystrophy: a native tissue model
    Behrooz Azizi
    Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 52:9291-7. 2011
    ..This study compared susceptibility of Fuchs endothelial corneal dystrophy (FECD) and normal corneal endothelial cells (CECs) to oxidative stress, and studied the mechanism of oxidative-stress-induced apoptosis in FECD-affected endothelium...
  8. doi request reprint Comparative analysis of human-derived feeder layers with 3T3 fibroblasts for the ex vivo expansion of human limbal and oral epithelium
    Sandhya M Sharma
    Schepens Eye Research Institute, 20 Staniford Street, Boston, MA 02114, USA
    Stem Cell Rev 8:696-705. 2012
    ..In conclusion, DF provides a promising substitute for 3T3 feeder cells during cultivation of xenobiotic-free corneal equivalents...
  9. pmc Inflammation and the nervous system: the connection in the cornea in patients with infectious keratitis
    Andrea Cruzat
    Ocular Surface Imaging Center, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 52:5136-43. 2011
    ..To study the density and morphologic characteristics of epithelial dendritic cells, as correlated to subbasal corneal nerve alterations in acute infectious keratitis (IK) by in vivo confocal microscopy (IVCM)...
  10. pmc Unusual presentation of presumed posterior polymorphous dystrophy associated with iris heterochromia, band keratopathy, and keratoconus
    Helene Y Lam
    Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    Cornea 29:1180-5. 2010
    ....
  11. pmc Topical bevacizumab in the treatment of corneal neovascularization: results of a prospective, open-label, noncomparative study
    Mohammad H Dastjerdi
    Cornea and Refractive Surgery Service, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Arch Ophthalmol 127:381-9. 2009
    ..To study the safety and efficacy of topical bevacizumab in the treatment of corneal neovascularization (NV)...
  12. doi request reprint Limbal stem cell deficiency and corneal neovascularization
    Pauline Lim
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles St, Boston, MA 02114, USA
    Semin Ophthalmol 24:139-48. 2009
    ..Further studies are needed to investigate the combination of limbal and stem cell transplantation and concurrent anti-angiogenic therapy...
  13. pmc Fuchs endothelial corneal dystrophy
    Hussain Elhalis
    Schepens Eye Research Institute, Boston, MA 02114, USA
    Ocul Surf 8:173-84. 2010
    ..This review expands upon the recent findings from proteomic and genetic studies and builds upon recent advances in understanding the causes of this common corneal disorder...
  14. ncbi request reprint Keratoglobus in association with posterior polymorphous dystrophy
    Mona Harissi-Dagher
    Department of Ophthalmology, Cornea and External Disease Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Cornea 26:1288-91. 2007
    ..To report a case of a 34-year-old woman presenting with keratoglobus and posterior polymorphous corneal dystrophy (PPMD)...