Research Topics
| K J JoshipuraSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Periodontal disease and biomarkers related to cardiovascular diseaseK J Joshipura
Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, MA 02115, USA
J Dent Res 83:151-5. 2004..Based on our data, periodontal disease showed significant associations with biomarkers of endothelial dysfunction and dyslipidemia, which may potentially mediate the association between periodontal and cardiovascular disease...
Pulpal inflammation and incidence of coronary heart diseaseKaumudi J Joshipura
Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, Massachusetts, USA
J Endod 32:99-103. 2006..38; 95% CI 1.14-1.67). There was no association among nondentists (RR = 1.03). Dental caries was not associated with CHD. The results suggest a possible modest association between pulpal inflammation and CHD...
Fruit and vegetable intake in relation to risk of ischemic strokeK J Joshipura
Department of Epidemiology, Harvard School of Public Health, Boston, Mass, USA
JAMA 282:1233-9. 1999..Few studies have evaluated the relationship between fruit and vegetable intake and cardiovascular disease...
Validity of a self-reported periodontal disease measureK J Joshipura
Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, MA 02115, USA
J Public Health Dent 56:205-12. 1996..The purpose of this study was to determine the validity of a self-reported periodontal disease measure for use in the Health Professionals Follow-up Study...
Possible explanations for the tooth loss and cardiovascular disease relationshipK J Joshipura
Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, MA USA
Ann Periodontol 3:175-83. 1998..rule out that confounding is a possible explanation for the tooth loss and CVD relationship, that prior periodontal disease may not completely explain the tooth loss-CVD relationship, and that the role of diet needs to be further explored..
Prospective study of fruit and vegetable consumption and incidence of colon and rectal cancersK B Michels
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
J Natl Cancer Inst 92:1740-52. 2000..Frequent consumption of fruit and vegetables has been associated with a reduced risk of colorectal cancer in many observational studies...
Tobacco use and incidence of tooth loss among US male health professionalsT Dietrich
Department of Health Policy and Health Services Research, Boston University Goldman School of Dental Medicine, 715 Albany St, 560, 3rd Floor, Boston, MA 02118, USA
J Dent Res 86:373-7. 2007..Current pipe/cigar smokers had a 20% (95% CI, 1.11, 1.30) increased risk of tooth loss compared with never- and former smokers of pipes/cigars...
The effect of fruit and vegetable intake on risk for coronary heart diseaseK J Joshipura
Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Ann Intern Med 134:1106-14. 2001..CONCLUSIONS: Consumption of fruits and vegetables, particularly green leafy vegetables and vitamin C-rich fruits and vegetables, appears to have a protective effect against coronary heart disease...
Alcohol consumption increases periodontitis riskW Pitiphat
Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA 02115, USA
J Dent Res 82:509-13. 2003..24 (1.09, 1.42); 5.0 to 14.9 g/day, 1.18 (1.04, 1.35); 15 to 29.9 g/day, 1.18 (1.01, 1.38); and > 30 g/day, 1.27 (1.08, 1.49). The results suggest that alcohol consumption is an independent modifiable risk factor for periodontitis...
Fruit and vegetable consumption and colorectal cancer incidenceK B Michels
Harvard University, Boston, MA, USA
IARC Sci Publ 156:139-40. 2002
An assessment of bone fluoride and osteosarcomaF M Kim
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
J Dent Res 90:1171-6. 2011..33 (95% CI: 0.56-3.15). No significant association between bone fluoride levels and osteosarcoma risk was detected in our case-control study, based on controls with other tumor diagnoses...
Fruit and vegetable intake and risk of major chronic diseaseHsin-Chia Hung
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
J Natl Cancer Inst 96:1577-84. 2004..The benefits appeared to be primarily for cardiovascular disease and not for cancer...
Maternal periodontitis and adverse pregnancy outcomesWaranuch Pitiphat
Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, MA, USA
Community Dent Oral Epidemiol 36:3-11. 2008..We evaluated periodontitis in relation to preterm birth (<37 weeks' gestation) and small-for-gestational-age (SGA, birth weight below the 10th percentile of birth weight for gestational age) among a group of medically insured women...
Validation of self-reported periodontal measures among health professionalsKaumudi J Joshipura
Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA 02115, USA
J Public Health Dent 62:115-21. 2002..Valid self-reported measures could provide a time- and cost-efficient alternative for large epidemiologic studies...
Whole-grain and fiber intakes and periodontitis risk in menAnwar T Merchant
Population Health Research Institute and the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
Am J Clin Nutr 83:1395-400. 2006..Diabetes and hyperglycemia increase periodontitis risk, severity, and extent. Increased whole-grain and fiber intakes are associated with improved insulin sensitivity and may therefore affect periodontitis risk...
Periodontitis and plasma C-reactive protein during pregnancyWaranuch Pitiphat
Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, MA, USA
J Periodontol 77:821-5. 2006..We examined the relationship between periodontitis and CRP among women who provided dental radiographs and had blood collected during early pregnancy, excluding smokers and diabetic patients...
Prospective study of alcohol consumption and risk of oral premalignant lesions in menNancy Nairi Maserejian
Department of Epidemiology, Harvard School of Dental Medicine, Boston, USA
Cancer Epidemiol Biomarkers Prev 15:774-81. 2006..Alcohol is an independent risk factor for OPL, regardless of beverage type or drinking pattern. Recommendations to reduce alcohol intake have the potential to reduce incidence of OPL in nonsmokers and smokers alike...
Validation of self-reported oral health measuresWaranuch Pitiphat
Harvard School of Dental Medicine, Harvard School of Public Health, 188 Longwood Avenue, Boston, MA 02115, USA
J Public Health Dent 62:122-8. 2002..There remains a need and potential to further develop self-report oral health measures that are valid for use in large population studies. Such self-report measures would yield great cost and time savings...
Plasma C-reactive protein in early pregnancy and preterm deliveryWaranuch Pitiphat
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
Am J Epidemiol 162:1108-13. 2005..64, 95% confidence interval: 0.94, 22.96) versus indicated delivery (odds ratio = 1.42, 95% confidence interval: 0.44, 4.61). These findings suggest that very high CRP levels in early pregnancy are associated with preterm delivery...
Can the relation between tooth loss and chronic disease be explained by socio-economic status?Kaumudi J Joshipura
Department of Oral Health Policy and Epidemiology Harvard School of Dental Medicine, Boston, MA 02115, USA
Eur J Epidemiol 20:203-4. 2005
The association between tooth loss and the self-reported intake of selected CVD-related nutrients and foods among US womenHsin-Chia Hung
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Community Dent Oral Epidemiol 33:167-73. 2005..CONCLUSIONS: Women with fewer teeth have unhealthier diets such as decreased intake of fruits and vegetables, which could increase CVD risk. Diet may partially explain associations between oral health and cardiovascular disease...
Use of preexisting radiographs for assessing periodontal disease in epidemiologic studiesWaranuch Pitiphat
Harvard School of Dental Medicine, Boston MA 02115, USA
J Public Health Dent 64:223-30. 2004..70 comparing radiographs taken within 5 years and 0.29 when the period extended beyond 5 years. CONCLUSION: Preexisting radiographs are feasible for use in epidemiologic studies and provide valid assessments of periodontal disease...
The association between tooth loss and coronary heart disease in men and womenHsin-Chia Hung
Harvard School of Public Health, Boston, MA 02115, USA
J Public Health Dent 64:209-15. 2004..CONCLUSIONS: This study showed a significant association between number of teeth at baseline and risk of coronary heart disease and the mechanisms to explain this association should be further clarified...
Periodontal disease, tooth loss, and incidence of ischemic strokeKaumudi J Joshipura
Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, Mass 02115, USA
Stroke 34:47-52. 2003..Periodontal and other infections have been suggested as potential risk factors for stroke. This study evaluates periodontal disease and tooth loss as risk factors for ischemic stroke...
Tooth loss and dietary intakeHsin-Chia Hung
Department of Epidemiology, Harvard School of Public Health, Boston, USA
J Am Dent Assoc 134:1185-92. 2003..PRACTICE IMPLICATIONS: Dietary evaluation and recommendations can be incorporated into dental visits to provide a greater benefit to patients...
Association between serum concentrations of 25-hydroxyvitamin D3 and periodontal disease in the US populationThomas Dietrich
Department of Periodontology and the Department of Oral Surgery and Oral Radiology, Charite, Humboldt University of Berlin, Germany
Am J Clin Nutr 80:108-13. 2004..Periodontal disease (PD) is a common chronic inflammatory disease and an important risk factor for tooth loss. Vitamin D might affect periodontal disease risk via an effect on bone mineral density (BMD) or via immunomodulatory effects...
The relationship between amalgam restorations and mercury levels in male dentists and nondental health professionalsAnil Joshi
Harvard School of Dental Medicine, Boston, MA 02115, USA
J Public Health Dent 63:52-60. 2003..The lack of association between nail mercury levels and number of amalgam restorations suggests that avoidance of mercury amalgam restorative materials cannot be justified by the presence of mercury released from dental amalgams...
The association between fruit and vegetable consumption and peripheral arterial diseaseHsin-Chia Hung
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Epidemiology 14:659-65. 2003..64-1.48) for fruit intake, and 0.76 (0.50-1.17) for vegetable intake. CONCLUSIONS: We did not find evidence that fruit and vegetable consumption protects against peripheral arterial disease, although a modest benefit cannot be excluded...
Oral health and peripheral arterial diseaseHsin-Chia Hung
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Circulation 107:1152-7. 2003..CONCLUSIONS: We found that incident tooth loss was significantly associated with PAD, especially among men with periodontal diseases. The results support a potential oral infection-inflammation pathway...
