R P Johnson

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Macaque models for AIDS vaccine development
    R P Johnson
    New England Regional Primate Research Center, Harvard Medical School, PO Box 9102, One Pine Hill Drive, Southborough, MA 01772, USA
    Curr Opin Immunol 8:554-60. 1996
  2. ncbi request reprint Protective immunity induced by live attenuated simian immunodeficiency virus
    R P Johnson
    Division of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
    Curr Opin Immunol 10:436-43. 1998
  3. pmc Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus
    R P Johnson
    Division of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, Massachusetts 01772, USA
    J Virol 71:7711-8. 1997
  4. ncbi request reprint Identification of multiple simian immunodeficiency virus (SIV)-specific CTL epitopes in sooty mangabeys with natural and experimentally acquired SIV infection
    A Kaur
    Division of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
    J Immunol 164:934-43. 2000
  5. ncbi request reprint An animal model for acute and persistent Epstein-Barr virus infection
    A Moghaddam
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Science 276:2030-3. 1997
  6. ncbi request reprint Mechanisms associated with thymocyte apoptosis induced by simian immunodeficiency virus
    M Rosenzweig
    Divisions ofImmunology and Pathology, New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
    J Immunol 165:3461-8. 2000
  7. ncbi request reprint Immune modulation of human B lymphocytes by gene transfer with recombinant Epstein-Barr virus amplicons
    F Wang
    Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Virol Methods 72:81-93. 1998
  8. pmc Efficient processing of the immunodominant, HLA-A*0201-restricted human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitope despite multiple variations in the epitope flanking sequences
    C Brander
    AIDS Research Center and Infectious Disease Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Virol 73:10191-8. 1999
  9. ncbi request reprint T-cell differentiation of human and non-human primate CD34+ hematopoietic progenitor cells using porcine thymic stroma
    M Rosenzweig
    Division of Immunology, Harvard Medical School, New England Regional Primate Research Center, Southborough, MA, USA
    Xenotransplantation 8:185-92. 2001
  10. ncbi request reprint Identification of primitive hematopoietic progenitor cells in the rhesus macaque
    M Rosenzweig
    Division of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
    J Med Primatol 30:36-45. 2001

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Macaque models for AIDS vaccine development
    R P Johnson
    New England Regional Primate Research Center, Harvard Medical School, PO Box 9102, One Pine Hill Drive, Southborough, MA 01772, USA
    Curr Opin Immunol 8:554-60. 1996
    ..Protection against disease or persistent infection may be achieved in the absence of sterilizing immunity, suggesting that new benchmarks for AIDS vaccines may be in order...
  2. ncbi request reprint Protective immunity induced by live attenuated simian immunodeficiency virus
    R P Johnson
    Division of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
    Curr Opin Immunol 10:436-43. 1998
    ....
  3. pmc Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus
    R P Johnson
    Division of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, Massachusetts 01772, USA
    J Virol 71:7711-8. 1997
    ....
  4. ncbi request reprint Identification of multiple simian immunodeficiency virus (SIV)-specific CTL epitopes in sooty mangabeys with natural and experimentally acquired SIV infection
    A Kaur
    Division of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
    J Immunol 164:934-43. 2000
    ..Longitudinal studies of viral load and sequence variation in CTL epitopes may provide useful information on the role of CTL in control or persistence of SIV infection in sooty mangabeys...
  5. ncbi request reprint An animal model for acute and persistent Epstein-Barr virus infection
    A Moghaddam
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Science 276:2030-3. 1997
    ..This system may be useful for studying the pathogenesis, prevention, and treatment of EBV infection and associated oncogenesis...
  6. ncbi request reprint Mechanisms associated with thymocyte apoptosis induced by simian immunodeficiency virus
    M Rosenzweig
    Divisions ofImmunology and Pathology, New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
    J Immunol 165:3461-8. 2000
    ..These changes peaked 14-21 days after infection at or just after peak viremia. This data further suggests disruption of the antiapoptotic pathway regulated by bcl-2 plays a critical role in SIV-induced apoptosis of thymocytes...
  7. ncbi request reprint Immune modulation of human B lymphocytes by gene transfer with recombinant Epstein-Barr virus amplicons
    F Wang
    Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Virol Methods 72:81-93. 1998
    ..Combining gene transfer with EBV infection may provide unique advantages for in vitro and in vivo gene transfer...
  8. pmc Efficient processing of the immunodominant, HLA-A*0201-restricted human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitope despite multiple variations in the epitope flanking sequences
    C Brander
    AIDS Research Center and Infectious Disease Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Virol 73:10191-8. 1999
    ..These data suggest that escape from this immunodominant CTL response is not frequently accomplished by changes in the epitope flanking sequences...
  9. ncbi request reprint T-cell differentiation of human and non-human primate CD34+ hematopoietic progenitor cells using porcine thymic stroma
    M Rosenzweig
    Division of Immunology, Harvard Medical School, New England Regional Primate Research Center, Southborough, MA, USA
    Xenotransplantation 8:185-92. 2001
    ....
  10. ncbi request reprint Identification of primitive hematopoietic progenitor cells in the rhesus macaque
    M Rosenzweig
    Division of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
    J Med Primatol 30:36-45. 2001
    ..Thus, as in humans, the CD34+38- population of rhesus macaque bone marrow is enriched for primitive, multipotent hematopoietic progenitor cells...
  11. pmc Differential dynamics of CD4(+) and CD8(+) T-lymphocyte proliferation and activation in acute simian immunodeficiency virus infection
    A Kaur
    Division of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, Massachusetts 01772, USA
    J Virol 74:8413-24. 2000
    ..Thus, divergent patterns of proliferation and activation are exhibited by CD4(+) and CD8(+) T lymphocytes in early SIV infection and may determine how these cells are differentially affected in AIDS...
  12. ncbi request reprint Emergence of cytotoxic T lymphocyte escape mutations in nonpathogenic simian immunodeficiency virus infection
    A Kaur
    Division of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
    Eur J Immunol 31:3207-17. 2001
    ..These results document the occurrence of CTL escape in a host that does not develop AIDS, and adds to the growing body of evidence that CTL exert significant selective pressure in SIV infection...
  13. pmc Vaccination with SIVmac239Deltanef activates CD4+ T cells in the absence of CD4 T-cell loss
    R K Reeves
    Division of Immunology, New England Primate Research Center, Harvard Medical School, Southborough, MA 01772 9102, USA
    J Med Primatol 38:8-16. 2009
    ....
  14. pmc Identification of highly attenuated mutants of simian immunodeficiency virus
    R C Desrosiers
    New England Regional Primate Research Center, Harvard Medical School, Southborough, Massachusetts 01772 9102, USA
    J Virol 72:1431-7. 1998
    ....
  15. pmc Emergence and kinetics of simian immunodeficiency virus-specific CD8(+) T cells in the intestines of macaques during primary infection
    R S Veazey
    New England Regional Primate Research Center, Harvard Medical School, Southborough, Massachusetts 01772, USA
    J Virol 75:10515-9. 2001
    ....
  16. pmc Efficient entry inhibition of human and nonhuman primate immunodeficiency virus by cell surface-expressed gp41-derived peptides
    R C Zahn
    Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Gene Ther 15:1210-22. 2008
    ....
  17. ncbi request reprint Induction of cytotoxic T lymphocyte and antibody responses to enhanced green fluorescent protein following transplantation of transduced CD34(+) hematopoietic cells
    M Rosenzweig
    New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
    Blood 97:1951-9. 2001
    ..Blood. 2001;97:1951-1959)..