Amy C Janes

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Brain fMRI reactivity to smoking-related images before and during extended smoking abstinence
    Amy C Janes
    Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA
    Exp Clin Psychopharmacol 17:365-73. 2009
  2. pmc Neural substrates of attentional bias for smoking-related cues: an FMRI study
    Amy C Janes
    Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA
    Neuropsychopharmacology 35:2339-45. 2010
  3. pmc GABA levels in the dorsal anterior cingulate cortex associated with difficulty ignoring smoking-related cues in tobacco-dependent volunteers
    Amy C Janes
    Brain Imaging Center, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA
    Neuropsychopharmacology 38:1113-20. 2013
  4. pmc Prefrontal and limbic resting state brain network functional connectivity differs between nicotine-dependent smokers and non-smoking controls
    Amy C Janes
    Brain Imaging Center, McLean Hospital, Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA
    Drug Alcohol Depend 125:252-9. 2012
  5. pmc Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women
    Amy C Janes
    Brain Imaging Center, McLean Hospital, Harvard Medical School, 115 Mill St, Belmont, MA 02478, USA
    Drug Alcohol Depend 120:7-13. 2012
  6. pmc Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence
    Amy C Janes
    Brain Imaging Center McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 67:722-9. 2010
  7. doi The involvement of type IV phosphodiesterases in cocaine-induced sensitization and subsequent pERK expression in the mouse nucleus accumbens
    Amy C Janes
    Department of Psychology, Boston University, Boston, MA 02215, USA
    Psychopharmacology (Berl) 206:177-85. 2009
  8. pmc Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome
    Yasmin Mashhoon
    McLean Hospital Harvard Medical School, 115 Mill St, Belmont, MA 02478, United States
    Prog Neuropsychopharmacol Biol Psychiatry 35:1709-13. 2011
  9. pmc A method for conducting functional MRI studies in alert nonhuman primates: initial results with opioid agonists in male cynomolgus monkeys
    Marc J Kaufman
    McLean Imaging Center, McLean Hospital, Belmont, MA 02478, USA
    Exp Clin Psychopharmacol 21:323-31. 2013
  10. pmc A double-blind, placebo-controlled trial of the NMDA glycine site antagonist, GW468816, for prevention of relapse to smoking in females
    A Eden Evins
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Psychopharmacol 31:597-602. 2011

Detail Information

Publications21

  1. pmc Brain fMRI reactivity to smoking-related images before and during extended smoking abstinence
    Amy C Janes
    Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA
    Exp Clin Psychopharmacol 17:365-73. 2009
    ..In some brain regions, fMRI smoking cue reactivity is increased during extended smoking abstinence in comparison to the prequit state, which may contribute to persisting relapse vulnerability...
  2. pmc Neural substrates of attentional bias for smoking-related cues: an FMRI study
    Amy C Janes
    Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA
    Neuropsychopharmacology 35:2339-45. 2010
    ..Treatments capable of inhibiting shifts to drug cue-induced memories and internal states may lead to personalized tobacco dependence treatment for smokers with high attentional bias to smoking-related stimuli...
  3. pmc GABA levels in the dorsal anterior cingulate cortex associated with difficulty ignoring smoking-related cues in tobacco-dependent volunteers
    Amy C Janes
    Brain Imaging Center, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA
    Neuropsychopharmacology 38:1113-20. 2013
    ..This newly discovered relationship between dACC GABA and attentional bias provides evidence for a neurochemical target, which may aid smoking cessation in highly cue-reactive individuals...
  4. pmc Prefrontal and limbic resting state brain network functional connectivity differs between nicotine-dependent smokers and non-smoking controls
    Amy C Janes
    Brain Imaging Center, McLean Hospital, Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA
    Drug Alcohol Depend 125:252-9. 2012
    ..To investigate whether networks containing these regions differ between nicotine dependent female smokers and age-matched female non-smokers, we employed functional MRI (fMRI) at rest...
  5. pmc Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women
    Amy C Janes
    Brain Imaging Center, McLean Hospital, Harvard Medical School, 115 Mill St, Belmont, MA 02478, USA
    Drug Alcohol Depend 120:7-13. 2012
    ..The relationship between this SNP and other factors contributing to smoking behavior such as smoking cue reactivity is unclear...
  6. pmc Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence
    Amy C Janes
    Brain Imaging Center McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 67:722-9. 2010
    ..We hypothesized that functional magnetic resonance imaging (fMRI) reactivity to smoking-related cues, measured before a quit attempt, could identify smokers with heightened relapse vulnerability...
  7. doi The involvement of type IV phosphodiesterases in cocaine-induced sensitization and subsequent pERK expression in the mouse nucleus accumbens
    Amy C Janes
    Department of Psychology, Boston University, Boston, MA 02215, USA
    Psychopharmacology (Berl) 206:177-85. 2009
    ....
  8. pmc Anterior cingulate proton spectroscopy glutamate levels differ as a function of smoking cessation outcome
    Yasmin Mashhoon
    McLean Hospital Harvard Medical School, 115 Mill St, Belmont, MA 02478, United States
    Prog Neuropsychopharmacol Biol Psychiatry 35:1709-13. 2011
    ..Growing evidence suggests that glutamate neurotransmission is involved in mediating nicotine dependence. We hypothesized that prior to a cessation attempt, dACC glutamate levels would be lower in relapse vulnerable smokers...
  9. pmc A method for conducting functional MRI studies in alert nonhuman primates: initial results with opioid agonists in male cynomolgus monkeys
    Marc J Kaufman
    McLean Imaging Center, McLean Hospital, Belmont, MA 02478, USA
    Exp Clin Psychopharmacol 21:323-31. 2013
    ..Our results suggest that our fMRI approach could be informative for comparing effects of opioid agonists...
  10. pmc A double-blind, placebo-controlled trial of the NMDA glycine site antagonist, GW468816, for prevention of relapse to smoking in females
    A Eden Evins
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Psychopharmacol 31:597-602. 2011
    ....
  11. doi Cigarette craving is associated with blunted reward processing in nicotine-dependent smokers
    Alyssa L Peechatka
    McLean Imaging Center, McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA Suffolk University, Department of Psychology, 41 Temple Street, Boston, MA 02114, USA Electronic address
    Drug Alcohol Depend 155:202-7. 2015
    ..Such an association would suggest that individuals with reduced reward responsivity may be at increased risk to experience nicotine craving...
  12. doi Insula-Dorsal Anterior Cingulate Cortex Coupling is Associated with Enhanced Brain Reactivity to Smoking Cues
    Amy C Janes
    1 McLean Imaging Center, Brain Imaging Center, McLean Hospital, Belmont, MA, USA 2 Department of Psychiatry, Harvard Medical School, Belmont, MA, USA
    Neuropsychopharmacology 40:1561-8. 2015
    ..Collectively, these data provide a more network-level understanding of the insula's role in nicotine dependence and shows a relationship between inherent brain organization and smoking cue-reactivity. ..
  13. doi Reward Responsiveness Varies by Smoking Status in Women with a History of Major Depressive Disorder
    Amy C Janes
    1 McLean Imaging Center, McLean Hospital, Harvard Medical School, Belmont, MA, USA 2 Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Neuropsychopharmacology 40:1940-6. 2015
    ..Therapies aimed at enhancing this reward-based deficit may be beneficial in the treatment of both nicotine dependence and MDD. ..
  14. pmc Memory retrieval of smoking-related images induce greater insula activation as revealed by an fMRI-based delayed matching to sample task
    Amy C Janes
    McLean Imaging Center, McLean Hospital, Harvard Medical School, Belmont, MA, USA
    Addict Biol 20:349-56. 2015
    ..Importantly, the results implicate the insula in the retrieval of smoking-related stimuli, which is relevant given the insula's emerging role in addiction. ..
  15. pmc An increase in tobacco craving is associated with enhanced medial prefrontal cortex network coupling
    Amy C Janes
    McLean Imaging Center, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, United States of America
    PLoS ONE 9:e88228. 2014
    ..This is the first demonstration confirming that an increase in craving is associated with enhanced brain region interactions, which may play a role in the experience of craving. ..
  16. pmc Role of the orbitofrontal cortex and dorsal striatum in regulating the dose-related effects of self-administered cocaine
    Kathleen M Kantak
    Department of Psychology, Boston University, Boston, MA 02215, USA
    Behav Brain Res 201:128-36. 2009
    ....
  17. doi Brain and cognition abnormalities in long-term anabolic-androgenic steroid users
    Marc J Kaufman
    McLean Imaging Center, McLean Hospital, The Department of Psychiatry, Harvard Medical School, 115 Mill St, Belmont, MA 02478, USA Electronic address
    Drug Alcohol Depend 152:47-56. 2015
    ..Anabolic-androgenic steroid (AAS) use is associated with psychiatric symptoms including increased aggression as well as with cognitive dysfunction. The brain effects of long-term AAS use have not been assessed in humans...
  18. pmc Altered intrinsic functional coupling between core neurocognitive networks in Parkinson's disease
    Deepti Putcha
    Department of Psychological and Brain Sciences, Boston University, Boston, MA 02115, USA Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA 02114, USA
    Neuroimage Clin 7:449-55. 2015
    ....
  19. pmc Positive reinforcement training in squirrel monkeys using clicker training
    Timothy E Gillis
    McLean Imaging Center, McLean Hospital, Harvard Medical School, Belmont, Massachusetts
    Am J Primatol 74:712-20. 2012
    ..These findings warrant future studies to determine whether PRT may be useful in reducing stress-induced experimental confounds in studies involving squirrel monkeys...
  20. pmc Medial temporal lobe functioning and structure in the spontaneously hypertensive rat: comparison with Wistar-Kyoto normotensive and Wistar-Kyoto hypertensive strains
    Audrey M Wells
    Department of Psychology, Program in Neuroscience and CELEST Science of Learning Center, Boston University, Boston, Massachusetts 02215, USA
    Hippocampus 20:787-97. 2010
    ..The latter characteristics might be used to develop a new animal model of age- or disease-related decline in hippocampal functioning...
  21. pmc Striatal morphology is associated with tobacco cigarette craving
    Amy C Janes
    McLean Imaging Center, McLean Hospital, Harvard Medical School, Belmont, MA, USA
    Neuropsychopharmacology 40:406-11. 2015
    ..The current findings confirm a relationship between striatal function and morphology and suggest that variation in striatal morphology may be a biomarker for craving severity. ..