Frederick A Jakobiec

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi Intratarsal keratinous cysts of the Meibomian gland: distinctive clinicopathologic and immunohistochemical features in 6 cases
    Frederick A Jakobiec
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 149:82-94. 2010
  2. doi Unifocal and multifocal reactive lymphoid hyperplasia vs follicular lymphoma of the ocular adnexa
    Rebecca C Stacy
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Am J Ophthalmol 150:412-426.e1. 2010
  3. doi An analysis of conjunctival and periocular venous malformations: clinicopathologic and immunohistochemical features with a comparison of racemose and cirsoid lesions
    Frederick A Jakobiec
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts Electronic address
    Surv Ophthalmol 59:236-44. 2014
  4. doi Androgen receptor identification in the diagnosis of eyelid sebaceous carcinomas
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts Electronic address
    Am J Ophthalmol 157:687-96.e1-2. 2014
  5. doi Eyelid sebaceous carcinoma: clinicopathologic and multiparametric immunohistochemical analysis that includes adipophilin
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts Electronic address
    Am J Ophthalmol 157:186-208.e2. 2014
  6. doi Clinicopathologic and immunohistochemical studies of conjunctival large cell acanthoma, epidermoid dysplasia, and squamous papilloma
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts Harvard Medical School, Boston, Massachusetts Electronic address
    Am J Ophthalmol 156:830-46. 2013
  7. doi Biopsy of an anterior episcleral nodule as an aid in managing a ciliary body melanocytic tumor
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Cornea 32:1174-7. 2013
  8. doi Complex orbital angiomyoma with features of a lymphangiohemangioma
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology and The Oculoplastics Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 29:e61-5. 2013
  9. doi Angiomyofibroma of the orbit: a hybrid of vascular leiomyoma and cavernous hemangioma
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 28:438-45. 2012
  10. doi The cytologic composition of dacryops: an immunohistochemical investigation of 15 lesions compared to the normal lacrimal gland
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 155:380-396.e1. 2013

Collaborators

Detail Information

Publications82

  1. doi Intratarsal keratinous cysts of the Meibomian gland: distinctive clinicopathologic and immunohistochemical features in 6 cases
    Frederick A Jakobiec
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 149:82-94. 2010
    ..To describe 6 patients representing a new entity of Meibomian gland keratinous cysts...
  2. doi Unifocal and multifocal reactive lymphoid hyperplasia vs follicular lymphoma of the ocular adnexa
    Rebecca C Stacy
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Am J Ophthalmol 150:412-426.e1. 2010
    ..To characterize the differentiating histopathologic and immunophenotypic features of reactive lymphoid hyperplasia (RLH) and follicular lymphoma of the ocular adnexa...
  3. doi An analysis of conjunctival and periocular venous malformations: clinicopathologic and immunohistochemical features with a comparison of racemose and cirsoid lesions
    Frederick A Jakobiec
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts Electronic address
    Surv Ophthalmol 59:236-44. 2014
    ..Other conditions not to be confused with congenital venous malformations include hemorrhagic lymphangiectasia (of Leber), hemorrhagic lymphangiomas, and complex lymphaticovenous malformations. ..
  4. doi Androgen receptor identification in the diagnosis of eyelid sebaceous carcinomas
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts Electronic address
    Am J Ophthalmol 157:687-96.e1-2. 2014
    ..To assess the role of androgen receptor detection in diagnosing eyelid sebaceous carcinomas and to compare it with that of adipophilin...
  5. doi Eyelid sebaceous carcinoma: clinicopathologic and multiparametric immunohistochemical analysis that includes adipophilin
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts Electronic address
    Am J Ophthalmol 157:186-208.e2. 2014
    ..To evaluate the fine cytopathologic features and immunohistochemistry of eyelid sebaceous carcinoma...
  6. doi Clinicopathologic and immunohistochemical studies of conjunctival large cell acanthoma, epidermoid dysplasia, and squamous papilloma
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts Harvard Medical School, Boston, Massachusetts Electronic address
    Am J Ophthalmol 156:830-46. 2013
    ..To evaluate clinicopathologically and immunohistochemically a spectrum of conjunctival squamous proliferations...
  7. doi Biopsy of an anterior episcleral nodule as an aid in managing a ciliary body melanocytic tumor
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Cornea 32:1174-7. 2013
    ..To demonstrate the value of a diagnostic biopsy of a fixed episcleral nodule overlying a uveal mass...
  8. doi Complex orbital angiomyoma with features of a lymphangiohemangioma
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology and The Oculoplastics Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 29:e61-5. 2013
    ..Such lesions can present significant surgical challenges due to incomplete pseudoencapsulation...
  9. doi Angiomyofibroma of the orbit: a hybrid of vascular leiomyoma and cavernous hemangioma
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 28:438-45. 2012
    ..The aim of this study was to describe a novel primary orbital vascular tumor combining elements of a vascular leiomyoma (angioleiomyoma) and a cavernous hemangioma...
  10. doi The cytologic composition of dacryops: an immunohistochemical investigation of 15 lesions compared to the normal lacrimal gland
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 155:380-396.e1. 2013
    ..To define the cytologic composition of the double-layered epithelial lining of dacryops (lacrimal duct cyst), improve histopathologic diagnosis, and better understand pathogenesis...
  11. doi Histopathologic proof for the origin of ectopic cilia of the eyelid skin
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street 3rd Floor, Boston, MA 02114, USA
    Graefes Arch Clin Exp Ophthalmol 251:985-8. 2013
    ..The origin of congenitally displaced cilia of the eyelid margin remains a controversial subject...
  12. doi Unilateral sporadic retinal dysplasia: results of histopathologic, immunohistochemical, chromosomal, genetic, and VEGF-A analyses
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA Email
    J AAPOS 15:579-86. 2011
    ..To describe new findings in a case of unilateral retinal dysplasia...
  13. doi Basaloid follicular hamartoma of the eyelid
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 28:e127-30. 2012
    ..Besides basal cell carcinomas, the differential diagnosis of basaloid follicular hamartoma includes fibrofolliculoma, tumor of the follicular infundibulum, poroma, and trabecular (Merkel cell) carcinoma...
  14. doi Palpebro-orbital apocrine cystadenoma: immunohistochemical verification of a unique variant with a critical differential diagnosis
    Frederick A Jakobiec
    David D Cogan Ophthalmic Pathology Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 26:245-9. 2010
    ..To describe a unique apocrine cystadenoma of the superonasal eyelid and anterior orbit...
  15. doi Recurrent blue nevus of the corneoscleral limbus
    Frederick A Jakobiec
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    Cornea 29:947-51. 2010
    ..To describe an unusual corneoscleral blue nevus...
  16. doi Bilateral conjunctival melanocytic nevi of simultaneous onset simulating conjunctivitis in a child
    Frederick A Jakobiec
    Harvard Medical School, Boston, MA, USA
    Cornea 29:937-40. 2010
    ..The differential diagnosis of much less likely disorders includes leukemia, lymphoid tumor (salmon patch), and conjunctival sarcoidosis, among other conditions. The patient has had no recurrence 3 years after surgery...
  17. doi Pigmented apocrine hidrocystoma of the caruncle
    Frederick A Jakobiec
    David G Cogan Laboratory of Eye Pathology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Cornea 29:1320-2. 2010
    ..To describe the clinical and immunopathologic features of the first convincing apocrine hidrocystoma of the caruncle that happened to be pigmented...
  18. doi A reappraisal of eyelid eccrine and apocrine hidrocystomas: microanatomic and immunohistochemical studies of 40 lesions
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 151:358-74.e2. 2011
    ..To establish reliable criteria for diagnosing eyelid eccrine and apocrine hidrocystomas...
  19. doi Retrocorneal membranes: a comparative immunohistochemical analysis of keratocytic, endothelial, and epithelial origins
    Frederick A Jakobiec
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Am J Ophthalmol 150:230-242.e2. 2010
    ..To determine through the use of immunohistochemistry the origins of retrocorneal cellular and fibrillar membranes...
  20. doi MDM2-positive atypical lipomatous neoplasm/well-differentiated liposarcoma versus spindle cell lipoma of the orbit
    Frederick A Jakobiec
    Cogan Ophthalmic Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 26:413-5. 2010
    ..To distinguish, in a 36-year-old man, an atypical lipomatous neoplasm/well-differentiated liposarcoma from a spindle cell lipoma in a recurrent orbital tumor...
  21. doi Eyelid basal cell carcinoma developing in an epidermoid cyst: a previously unreported event
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, 02114, USA
    Ophthal Plast Reconstr Surg 26:491-4. 2010
    ..This is the first example in the eyelid of an epidermoid cyst displaying malignant transformation. No matter how innocent they may appear, all small cystic or noncystic eyelid lesions should be submitted for pathologic evaluation...
  22. doi Blue nevus of the tarsus as the predominant component of a combined nevus of the eyelid
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 27:e94-6. 2011
    ..While the current lesion was proved to be an atypical nevus, all palpebral pigmented lesions should be routinely excised because many are melanomas...
  23. doi Non-syndromic supernumerary caruncles causing ocular irritation after cataract surgery: a critical review of caruncular dysgeneses
    Frederick A Jakobiec
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 149:398-404.e1-2. 2010
    ..To describe a patient with 2 ipsilateral supernumerary caruncles and to determine if they are predictive of associated abnormalities...
  24. doi Ocular adnexal lymphoid tumors: progress in need of clarification
    Frederick A Jakobiec
    Harvard Medical School, Massachusetts Eye and Ear Infirmary, David G Cogan Ophthalmic Pathology Lab, 243 Charles Street, Boston, MA 02114, USA
    Am J Ophthalmol 145:941-50. 2008
    ..To evaluate recent ophthalmic publications on ocular adnexal lymphomas (OALs) according to histopathologic and immunophenotypic criteria used in the diagnosis of systemic lymphomas (World Health Organization classification)...
  25. doi Complex palpebral odontogenic choristoma: A reappraisal of the origin of teeth-bearing periocular lesions
    Frederick A Jakobiec
    Department of Ophthalmology, the David G Cogan Ophthalmic Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 147:531-543.e1. 2009
    ..To describe the findings observed in a congenital ectopic tooth of the lower inner eyelid and explain its origin...
  26. doi Basal cell carcinoma of the eyelid with exceptional histomorphologic expressions
    Frederick A Jakobiec
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 25:232-4. 2009
    ....
  27. doi The white caruncle: sign of a keratinous cyst arising from a sebaceous gland duct
    Frederick A Jakobiec
    Department of Ophthalmology, David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Cornea 29:453-5. 2010
    ..To describe an acquired, smooth white lesion of the caruncle and to underscore the role of subsurface keratinizing squamous epithelium in its formation...
  28. doi Immunohistochemical studies of atypical conjunctival melanocytic nevi
    Frederick A Jakobiec
    David G Cogan Ophthalmic Pathology Laboratory, Massachusetts Eye and Ear Infirmary, 243 Charles St, Room 321, Boston, MA 02114, USA
    Arch Ophthalmol 127:970-80. 2009
    ..To evaluate with immunohistochemical methods 5 atypical melanocytic conjunctival lesions...
  29. doi Winer's dilated pore of the eyelid
    Frederick A Jakobiec
    David G Cogan Ophthalmic Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 25:411-3. 2009
    ..The wall displayed a proliferation of rete ridge-type structures that projected in the surrounding dermis. The lesion was diagnosed as a dilated pore of Winer and has not recurred after simple excision...
  30. doi Immunohistochemical studies of conjunctival nevi and melanomas
    Frederick A Jakobiec
    David D Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Arch Ophthalmol 128:174-83. 2010
    ..To evaluate the role of immunohistochemical methods in the diagnosis of benign and malignant conjunctival melanocytic proliferations...
  31. doi Canaliculops: clinicopathologic features and treatment with marsupialization
    Michael K Yoon
    Ophthalmic Plastic Surgery Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts Harvard Medical School, Boston, Massachusetts
    Am J Ophthalmol 156:1062-1068.e1. 2013
    ..To report the features of the rare and under-recognized condition of canaliculops (or canaliculocele) of the eyelid, which is a dilation of the canaliculus, and to evaluate treatment with marsupialization...
  32. doi Recurrent primary acquired melanosis with atypia involving a clear corneal phacoemulsification wound
    Kathryn Colby
    Cornea Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard School of Medicine, Boston, MA 02114, USA
    Cornea 30:114-6. 2011
    ..To report a case of corneal primary acquired melanosis (PAM) with atypia after cataract surgery...
  33. doi Diffuse large B-cell lymphoma of the orbit: clinicopathologic, immunohistochemical, and prognostic features of 20 cases
    Rebecca C Stacy
    David G Cogan Ophthalmic Pathology Laboratory, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Am J Ophthalmol 154:87-98.e1. 2012
    ..To evaluate a series of orbital diffuse large B-cell lymphomas (DLBCL) for prognostic features and therapeutic outcomes...
  34. doi Pleomorphic adenoma (formerly chondroid syringoma) of the eyelid margin with a pseudocystic appearance
    Sotiria Palioura
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Surv Ophthalmol 58:486-91. 2013
    ..These pathologic findings support an apocrine (gland of Moll) origin for this tumor, which is consistent with the fact that there are no eccrine glands at the eyelid margin. ..
  35. doi Newborn primary congenital glaucoma: histopathologic features of the anterior chamber filtration angle
    Lynn P Perry
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    J AAPOS 16:565-8. 2012
    ..These profound anatomic derangements explain why goniosurgery is frequently unsuccessful in cases of newborn glaucoma...
  36. doi Characterization of retrokeratoprosthetic membranes in the Boston type 1 keratoprosthesis
    Rebecca C Stacy
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, and Harvard Medical School, Boston, MA 02114, USA
    Arch Ophthalmol 129:310-6. 2011
    ..To evaluate retroprosthetic membranes that can occur in 25% to 65% of patients with the Boston type 1 keratoprosthesis (KPro)...
  37. doi Inadvertent filtering bleb due to corneal stromal wick syndrome
    Tarek Alasil
    Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    J Glaucoma 22:e14-5. 2013
    ....
  38. doi Intraorbital metastasis from solitary fibrous tumor
    Mrinali M Patel
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 29:e76-9. 2013
    ..Surgical excision cured his ocular symptoms, although he died 3 months later from brain and widespread metastases...
  39. doi Reactive retinal astrocytic tumors (so-called vasoproliferative tumors): histopathologic, immunohistochemical, and genetic studies of four cases
    Lynn J Poole Perry
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    Am J Ophthalmol 155:593-608.e1. 2013
    ..To evaluate the cellular nature of and diagnostic terminology used in connection with acquired retinal "vasoproliferative tumors."..
  40. doi Pythium insidiosum keratitis in Israel
    Tasha Y Tanhehco
    Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Eye Contact Lens 37:96-8. 2011
    ..To report with morphologic and phylogenetic speciation the first case from Israel of Pythium insidiosum keratitis associated with contact-lens wear...
  41. doi Intraocular pressure measurement by radio wave telemetry
    Amit Todani
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02445, USA
    Invest Ophthalmol Vis Sci 52:9573-80. 2011
    ..To determine the biocompatibility of a new wireless intraocular pressure (IOP) transducer (WIT) in rabbit eyes and to correlate its measurements with other pressure-measuring devices...
  42. doi Keratinous cyst of the palpebral conjunctiva
    Frederick A Jakobiec
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Ophthal Plast Reconstr Surg 25:337-9. 2009
    ..These histopathologic features are characteristic of trichilemmal keratinization, a heretofore undescribed metaplasia of the conjunctival epithelium...
  43. doi Immunohistochemical investigations of orbital infantile hemangiomas and adult encapsulated cavernous venous lesions (malformation versus hemangioma)
    Tammy H Osaki
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 29:183-95. 2013
    ....
  44. doi IgG4-related systemic disease as a cause of "idiopathic" orbital inflammation, including orbital myositis, and trigeminal nerve involvement
    Zachary S Wallace
    Department of Medicine, Harvard Medical School, Cambridge, Massachusetts, USA
    Surv Ophthalmol 57:26-33. 2012
    ..We review the differential of idiopathic orbital inflammatory disease, including IgG4-RD, and emphasize the need for biopsy for accurate diagnosis and to guide appropriate treatment...
  45. doi Paraneoplastic conjunctival cicatrization: two different pathogenic types
    Audrey E Ahuero
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthalmology 117:659-64. 2010
    ..To describe the clinical and immunopathologic features of patients with 2 different types of paraneoplastic conjunctival cicatrization...
  46. doi Treatment of lisch corneal dystrophy with photorefractive keratectomy and mitomycin C
    Matthew M Wessel
    Department of Ophthalmology, New York Presbyterian Hospital, Weill Cornell Medical College of Cornell University, New York, NY, USA
    Cornea 30:481-5. 2011
    ..To describe a case of Lisch dystrophy; review the clinical, histopathologic, and electron microscopic features of this entity; and discuss a novel treatment approach using photorefractive keratectomy (PRK) and mitomycin C (MMC)...
  47. doi Incipient corneoscleral xanthogranuloma with S-100 positivity in a teenager
    Justin M Kanoff
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    Cornea 29:688-90. 2010
    ..To present a case of a corneoscleral juvenile xanthogranuloma (JXG) with diagnostically challenging features...
  48. doi Descemet's stripping endothelial keratoplasty: an effective treatment for toxic anterior segment syndrome with histopathologic findings
    Roberto Pineda
    Cornea and Refractive Surgery Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    Cornea 29:694-7. 2010
    ..To report Descemet's stripping endothelial keratoplasty (DSEK) as a treatment for corneal edema associated with toxic anterior segment syndrome...
  49. doi Subepidermal calcified nodule of the eyelid
    John Nguyen
    Ophthalmic Plastic Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 24:494-5. 2008
    ..We report a case of a 9-year-old boy with a nodule of the right upper eyelid simulating Molluscum contagiosum. The histopathologic examination of the excised nodule confirmed the diagnosis...
  50. doi A review of advanced genetic testing for clinical prognostication in uveal melanoma
    Xiang Q Werdich
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA and
    Semin Ophthalmol 28:361-71. 2013
    ..We further describe the variety of genetic tests available for prognostication of UM, and provide a critical assessment of the respective advantages and disadvantages of these tools...
  51. doi Keratinizing cyst of the lacrimal punctum
    Yoshihiro Yonekawa
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, MA 02114, USA
    Cornea 32:883-5. 2013
    ..To describe the clinical and histopathologic features of the first reported punctal keratinizing cyst...
  52. doi Isolated unilateral linear epidermal nevus of the upper eyelid
    Alison B Callahan
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 28:e135-8. 2012
    ..For focal lesions like the present one, local excision is appropriate. A select differential diagnosis of histopathologically related conditions is provided...
  53. doi Corneal anomalies in newborn primary congenital glaucoma
    Sureka Thiagalingam
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
    J Pediatr Ophthalmol Strabismus 46:241-4. 2009
    ..The corneal changes seen in this patient may be specific to primary congenital glaucoma and may contribute to the corneal clouding seen so frequently in these patients...
  54. doi Idiopathic subfoveal choroidal neovascular membrane in a 21-month-old child: ultrastructural features and implication for membranogenesis
    Anthony B Daniels
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114 3096, USA
    J AAPOS 14:244-50. 2010
    ....
  55. doi Congenital pupillary-iris-lens membrane with goniodysgenesis: histopathologic findings in an enucleated eye
    Alexander Demidenko
    Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    J Pediatr Ophthalmol Strabismus 47:178-82. 2010
    ..Incomplete development of the iris may be partly attributable to an abnormality of stromal development and inductions by the anterior neuroectodermal layer, together with anomalies of the pupillo-iridial vasculature...
  56. doi Clinicopathologic and immunohistochemical features of pigmented Basal cell carcinomas of the eyelids
    Maria Kirzhner
    David G Cogan Ophthalmic Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Room 321, 243 Charles St, Boston, MA 02114, USA
    Am J Ophthalmol 153:242-252.e2. 2012
    ..To describe the clinical and microscopic features of pigmented basal cell carcinomas (pBCC) of the eyelid...
  57. doi Conjunctival melanoma arising from primary acquired melanosis in a patient with neurofibromatosis type I
    Rebecca C Stacy
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard School of Medicine, Boston, MA 02114, USA
    Cornea 29:232-4. 2010
    ..To describe a case of conjunctival malignant melanoma (MM) arising from primary acquired melanosis in a patient with neurofibromatosis type 1 (NF-1)...
  58. doi Recurrent conjunctival dermoid cyst with reactive lymphoid hyperplasia
    Rebecca C Stacy
    Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02116, USA
    Ophthal Plast Reconstr Surg 27:e28-30. 2011
    ..The lesion did not recur after 14 months of follow-up...
  59. doi Eyelid varix with phlebolith formation, thrombus recanalization, and early intravascular papillary endothelial hyperplasia
    Fouad R Zakka
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA
    Ophthal Plast Reconstr Surg 27:e8-11. 2011
    ..The clinical differential diagnosis is reviewed...
  60. doi Collagenous fibroma (desmoplastic fibroblastoma) of the orbital rim
    Rebecca C Stacy
    David G Cogan Ophthalmic Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 29:e101-4. 2013
    ..The current collagenous fibroma arose from the periosteum to grow exophytically, causing minimal bone changes. A literature review shows that this condition predominantly affects middle-aged and older adults rather than children. ..
  61. doi Comparison of tumor-associated vasculatures in uveal and cutaneous melanomas
    Pooja Bhat
    David G Cogan Ophthalmic Pathology Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    Semin Ophthalmol 24:166-71. 2009
    ....
  62. doi Keratinous cyst of the palpebral conjunctiva: new observations
    Pia R Mendoza
    David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, MA 02114, USA
    Cornea 32:513-6. 2013
    ..To describe an acquired keratinizing cyst of the palpebral conjunctiva...
  63. pmc Surgical management and ultrastructural study of choroidal neovascularization in punctate inner choroidopathy after bevacizumab
    Sophia I Pachydaki
    Department of Ophthalmology, Weill Cornell Medical College, New York, NY, USA
    J Ophthalmic Inflamm Infect 2:29-37. 2012
    ..This study aims to describe surgical management results and the pathologic features of choroidal neovascularization (CNV) secondary to punctate inner choroidopathy (PIC) following anti-vascular endothelial growth factor treatment...
  64. doi Monocular nasal hemianopia from atypical sphenoid wing meningioma
    Rebecca C Stacy
    Department of Neuro Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
    J Neuroophthalmol 30:160-3. 2010
    ..The tumor was debulked surgically, and the patient's visual field defect improved...
  65. doi Giant dacryocystomucopyocele in an adult: a review of lacrimal sac enlargements with clinical and histopathologic differential diagnoses
    Lynn J P Perry
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Surv Ophthalmol 57:474-85. 2012
    ....
  66. doi An improved approach to diagnosing and treating conjunctival mucoepidermoid carcinoma
    Jessica K Rankin
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Surv Ophthalmol 57:337-46. 2012
    ..Results with radiotherapy and cryotherapy for deep scleral invasion have been unpredictable or unacceptable compared with surgery...
  67. doi Epicorneal polypoidal lipodermoid: lack of association of central corneal lesions with goldenhar syndrome verified with a review of the literature
    Frederick A Jakobiec
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA
    Surv Ophthalmol 55:78-84. 2010
    ..Other epibulbar choristomas that can be confused with lipodermoids are described...
  68. ncbi Choroidal neovascular membranes treated with photodynamic therapy
    Jorge G Arroyo
    Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Mass 02114, USA
    Arch Ophthalmol 121:898-903. 2003
  69. doi Primary T-cell lymphoma of the retina and cerebellum: immunophenotypic and gene rearrangement confirmation
    Pooja V Bhat
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Am J Ophthalmol 148:350-60. 2009
    ..To document fully the first credible primary T-cell lymphoma of the retina and central nervous system in a 71-year-old man...
  70. doi Desmoplastic trichoepithelioma: report of a unique periocular case
    Maria Kirzhner
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 28:e121-3. 2012
    ..Surgical therapy should aim at complete excision but does not have to be as extensive or aggressive as that used for morpheic or sclerosing BCC because of its lack of diffusely infiltrating margins...
  71. doi Focal blue nevus of the eyelid margin (mucocutaneous junction): a report of a unique case with a review of the literature
    Maria Kirzhner
    Department of Ophthalmology, Harvard Medical School, Boston, MA, USA
    Ophthal Plast Reconstr Surg 27:338-42. 2011
    ..To describe the first isolated and focal benign blue nevus of the eyelid margin...
  72. pmc Biocompatibility and biofilm inhibition of N,N-hexyl,methyl-polyethylenimine bonded to Boston Keratoprosthesis materials
    Irmgard Behlau
    Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, United States
    Biomaterials 32:8783-96. 2011
    ..Likewise, no toxicity or adverse reactivity was detected with HMPEI-derivatized PMMA or titanium compared to those of the control materials after intrastromal or anterior chamber implantation in rabbits in vivo...
  73. doi Exaggerated postsurgical inflammation in a patient with insufficiently treated Addison disease
    Mark P Hatton
    Ophthalmic Consultants of Boston, Boston, Massachusetts 02114, USA
    Ophthal Plast Reconstr Surg 25:67-9. 2009
    ..He was treated for presumed orbital cellulitis without improvement. Increasing the corticosteroid dose for his Addison disease resulted in complete resolution of the inflammation...
  74. pmc Influence of aromatase absence on the gene expression and histology of the mouse meibomian gland
    Raheleh Rahimi Darabad
    Schepens Eye Research Institute, Department of Ophthalmology, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 54:987-98. 2013
    ..To begin to test this hypothesis, we examined the influence of aromatase absence, which completely eliminates estrogen production, on glandular gene expression and histology in male and female mice...
  75. doi Bacterial and mucopeptide concretions of the lacrimal drainage system: an analysis of 30 cases
    Lynn J Poole Perry
    Department of Ophthalmology and the Cogan Eye Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA
    Ophthal Plast Reconstr Surg 28:126-33. 2012
    ..To demonstrate the histopathologic characteristics of different types of lacrimal drainage system concretions with clinical correlations...
  76. doi Orbital perineurioma in the setting of dacryocystitis
    Royce W S Chen
    Division of Ophthalmic Plastic and Reconstructive Surgery, Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia College of Physicians and Surgeons, New York, New York, USA
    Ophthal Plast Reconstr Surg 28:e51-5. 2012
    ..Malignant transformation is virtually unknown, even with incomplete excision. The differential diagnosis includes neurofibroma, schwannoma, leiomyoma, solitary fibrous tumor (CD34 positive), and low-grade fibromyxoid sarcoma...
  77. doi Optic nerve involvement with panuveitis in Sweet syndrome
    Ann Marie Lobo
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ocul Immunol Inflamm 19:167-70. 2011
    ..To report a case of a patient with optic nerve involvement in neuro-Sweet syndrome and review the literature on this systemic disease...
  78. doi Ocular cicatricial pemphigoid: a review of clinical features, immunopathology, differential diagnosis, and current management
    Maria Kirzhner
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, MA 02114, USA
    Semin Ophthalmol 26:270-7. 2011
    ..This article is an update of the pathogenesis, ocular findings, differential diagnosis, and approaches to treatment...
  79. ncbi Lymphoma-associated retinopathy
    King W To
    Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthalmology 109:2149-53. 2002
    ..To describe the clinical, electrophysiologic, and serologic findings in a patient with retinal degeneration associated with Hodgkin's lymphoma...
  80. ncbi Clinicopathologic reports, case reports, and small case series: surgical removal and histopathologic findings of a subfoveal neovascular membrane associated with choroidal osteoma
    Bradley S Foster
    Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Arch Ophthalmol 121:273-6. 2003
  81. doi Orbital involvement in Bing-Neel syndrome
    Rebecca C Stacy
    Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
    J Neuroophthalmol 30:255-9. 2010
    ..The rare neuro-ophthalmic manifestations of BNS may require a multifaceted approach to therapy...
  82. doi Chronic herpes simplex scleritis: characterization of 9 cases of an underrecognized clinical entity
    Pooja V Bhat
    David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Am J Ophthalmol 148:779-789.e2. 2009
    ..To characterize in detail persistent and recalcitrant infectious scleritis resulting from herpes simplex virus (HSV)...