E Israel

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma
    E Israel
    Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int Arch Allergy Immunol 124:183-6. 2001
  2. ncbi Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment
    J M Drazen
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Genet 22:168-70. 1999
  3. ncbi A neuronal NO synthase (NOS1) gene polymorphism is associated with asthma
    H Grasemann
    Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Biochem Biophys Res Commun 272:391-4. 2000
  4. ncbi How does airway inflammation modulate asthmatic airway constriction? An antigen challenge study
    A C Henderson
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    J Appl Physiol 95:873-82; discussion 863. 2003
  5. ncbi Eotaxin expression after segmental allergen challenge in subjects with atopic asthma
    C M Lilly
    Combined Program in Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Respir Crit Care Med 163:1669-75. 2001
  6. ncbi Airway constriction pattern is a central component of asthma severity: the role of deep inspirations
    K R Lutchen
    Respiratory and Physiological Systems Identification Laboratory, Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Am J Respir Crit Care Med 164:207-15. 2001
  7. ncbi Variant eotaxin: its effects on the asthma phenotype
    H Nakamura
    Combined Program in Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Allergy Clin Immunol 108:946-53. 2001
  8. pmc TSLP polymorphisms are associated with asthma in a sex-specific fashion
    G M Hunninghake
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Allergy 65:1566-75. 2010
  9. ncbi Clinical predictors of health-related quality of life depend on asthma severity
    M L Moy
    Division of Pulmonary and Critical Care Medicine and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Respir Crit Care Med 163:924-9. 2001
  10. doi HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults
    J Lasky-Su
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Clin Exp Allergy 42:1724-33. 2012

Collaborators

Detail Information

Publications19

  1. ncbi Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma
    E Israel
    Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int Arch Allergy Immunol 124:183-6. 2001
    ..Polymorphisms of the beta(2)-adrenergic receptor (beta(2)-AR) can affect its regulation; however, results of smaller studies of the effects of such polymorphisms on response to beta-agonist therapy have been inconsistent...
  2. ncbi Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment
    J M Drazen
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Genet 22:168-70. 1999
    ..Such an effect indicates an interaction between gene promoter sequence variants and drug-treatment responses, that is, a pharmacogenetic effect of a promoter sequence on treatment responses...
  3. ncbi A neuronal NO synthase (NOS1) gene polymorphism is associated with asthma
    H Grasemann
    Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Biochem Biophys Res Commun 272:391-4. 2000
    ..Total serum IgE was not associated with any allele of the polymorphism. These findings provide support, from case-control association analysis, for NOS1 as a candidate gene for asthma...
  4. ncbi How does airway inflammation modulate asthmatic airway constriction? An antigen challenge study
    A C Henderson
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    J Appl Physiol 95:873-82; discussion 863. 2003
    ..These data support the hypothesis that variability in responsiveness among asthmatic subjects derives from intrinsic differences in smooth muscle response to inflammation...
  5. ncbi Eotaxin expression after segmental allergen challenge in subjects with atopic asthma
    C M Lilly
    Combined Program in Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Respir Crit Care Med 163:1669-75. 2001
    ....
  6. ncbi Airway constriction pattern is a central component of asthma severity: the role of deep inspirations
    K R Lutchen
    Respiratory and Physiological Systems Identification Laboratory, Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Am J Respir Crit Care Med 164:207-15. 2001
    ....
  7. ncbi Variant eotaxin: its effects on the asthma phenotype
    H Nakamura
    Combined Program in Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Allergy Clin Immunol 108:946-53. 2001
    ..Eotaxin, a CC chemokine expressed in the asthmatic lung, has been associated with impaired lung function. The role of its variant form is unknown...
  8. pmc TSLP polymorphisms are associated with asthma in a sex-specific fashion
    G M Hunninghake
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Allergy 65:1566-75. 2010
    ..Single nucleotide polymorphisms (SNPs) in thymic stromal lymphopoietin (TSLP) have been associated with IgE (in girls) and asthma (in general). We sought to determine whether TSLP SNPs are associated with asthma in a sex-specific fashion...
  9. ncbi Clinical predictors of health-related quality of life depend on asthma severity
    M L Moy
    Division of Pulmonary and Critical Care Medicine and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Respir Crit Care Med 163:924-9. 2001
    ..We conclude that the independent determinants of HRQL vary according to asthma severity and change with asthma treatment...
  10. doi HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults
    J Lasky-Su
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Clin Exp Allergy 42:1724-33. 2012
    ..An important genetic component to asthma susceptibility has long been recognized, most recently through the identification of several genes (e.g., ORMDL3, PDE4D, HLA-DQ, and TLE4) via genome-wide association studies...
  11. ncbi Exhaled nitric oxide in patients with asthma: association with NOS1 genotype
    M E Wechsler
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Respir Crit Care Med 162:2043-7. 2000
    ....
  12. ncbi Inhaled albuterol, but not intravenous lidocaine, protects against intubation-induced bronchoconstriction in asthma
    A D Maslow
    Department of Anesthesia, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Anesthesiology 93:1198-204. 2000
    ....
  13. ncbi Effects of inhaled glucocorticoids on bone density in premenopausal women
    E Israel
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 345:941-7. 2001
    ..In a three-year prospective study, we examined the relation between the dose of inhaled glucocorticoids and the rate of bone loss in premenopausal women with asthma...
  14. ncbi Tracking variations in airway caliber by using total respiratory vs. airway resistance in healthy and asthmatic subjects
    L D Black
    Department of Biomedical Engineering, 44 Cummington St, Boston, MA 02215, USA
    J Appl Physiol 95:511-8. 2003
    ..We conclude that the volume dependence of Rcw can bias the presumed net change in airway caliber during tidal breathing and a DI but would not distort assessment of maximum airway dilation...
  15. pmc The effect of lung stretch during sleep on airway mechanics in overweight and obese asthma
    L M Campana
    Department of Biomedical Engineering, Boston University, Boston, MA, United States
    Respir Physiol Neurobiol 185:304-12. 2013
    ..01), but R(low) was unchanged. High R(up) was observed in asthma, which reduced with BPAP. We conclude that the upper airway is a major component of R(rs) and larger lung volume changes may be required to alter R(low)...
  16. ncbi Atopic asthma: differential activation phenotypes among memory T helper cells
    M L Lara-Marquez
    Respiratory Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
    Clin Exp Allergy 31:1232-41. 2001
    ....
  17. ncbi A role for the C3a anaphylatoxin receptor in the effector phase of asthma
    A A Humbles
    Ina Sue Perlmutter Laboratory, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 406:998-1001. 2000
    ..We propose that, in addition to acquired immune responses, the innate immune system and complement (C3a in particular) are involved in the pathogenesis of asthma...
  18. ncbi Genetic analysis in the Asthma Clinical Research Network
    P E Forand
    Department of Health Evaluation Sciences, College of Medicine, Pennsylvania State University, Hershey, PA, USA
    Control Clin Trials 22:196S-206S. 2001
    ....
  19. ncbi ALOX5 promoter genotype, asthma severity and LTC production by eosinophils
    O Kalayci
    Hacettepe University School of Medicine, Pediatric Allergy and Asthma Unit, Hacettepe, Ankara, Turkey
    Allergy 61:97-103. 2006
    ..The relationship of ALOX5 variants to asthma severity and leukotriene production by eosinophils is unknown...