Steven E Hyman

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Neurotransmitters
    Steven E Hyman
    Harvard University, Cambridge, Massachusetts 02138, USA
    Curr Biol 15:R154-8. 2005
  2. pmc Might stimulant drugs support moral agency in ADHD children?
    Steven Edward Hyman
    Stanley Center, Broad Institute of Harvard and MIT, 7 Cambridge Center 5015, Cambridge, MA 02142, USA
    J Med Ethics 39:369-70; discussion 372-3. 2013
  3. doi request reprint Revolution stalled
    Steven E Hyman
    Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
    Sci Transl Med 4:155cm11. 2012
  4. pmc Public health contributions
    Steven E Hyman
    Schizophr Bull 33:1151-2. 2007
  5. ncbi request reprint Addiction: a disease of learning and memory
    Steven E Hyman
    Department of Neurobiology, Harvard Medical School, Boston, MA, USA
    Am J Psychiatry 162:1414-22. 2005
  6. ncbi request reprint The diagnosis of mental disorders: the problem of reification
    Steven E Hyman
    Department of Neurobiology, Harvard Medical School, Harvard University, Cambridge, Massachusetts 02138, USA
    Annu Rev Clin Psychol 6:155-79. 2010
  7. pmc How might cocaine interfere with brain development?
    Steven E Hyman
    Harvard University, Cambridge, Massachusetts, United States of America
    PLoS Med 5:e130. 2008
  8. ncbi request reprint Neural mechanisms of addiction: the role of reward-related learning and memory
    Steven E Hyman
    Office of the Provost, Harvard University, Cambridge, Massachusetts 02138, USA
    Annu Rev Neurosci 29:565-98. 2006
  9. doi request reprint Cognitive enhancement: promises and perils
    Steven E Hyman
    Office of the Provost, Massachusetts Hall, Harvard University, Cambridge, MA 02138, USA
    Neuron 69:595-8. 2011
  10. ncbi request reprint Can neuroscience be integrated into the DSM-V?
    Steven E Hyman
    Harvard University, Massachusetts Hall, Cambridge, Massachusetts 02138, USA
    Nat Rev Neurosci 8:725-32. 2007

Detail Information

Publications30

  1. ncbi request reprint Neurotransmitters
    Steven E Hyman
    Harvard University, Cambridge, Massachusetts 02138, USA
    Curr Biol 15:R154-8. 2005
  2. pmc Might stimulant drugs support moral agency in ADHD children?
    Steven Edward Hyman
    Stanley Center, Broad Institute of Harvard and MIT, 7 Cambridge Center 5015, Cambridge, MA 02142, USA
    J Med Ethics 39:369-70; discussion 372-3. 2013
    ..These findings are consistent with laboratory evidence that stimulant drugs in therapeutic doses improve cognitive control over thought and behavior...
  3. doi request reprint Revolution stalled
    Steven E Hyman
    Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
    Sci Transl Med 4:155cm11. 2012
    ..In this Commentary, I develop a view of what has gone wrong scientifically and ask what can be done to address this parlous situation...
  4. pmc Public health contributions
    Steven E Hyman
    Schizophr Bull 33:1151-2. 2007
  5. ncbi request reprint Addiction: a disease of learning and memory
    Steven E Hyman
    Department of Neurobiology, Harvard Medical School, Boston, MA, USA
    Am J Psychiatry 162:1414-22. 2005
    ..The author summarizes the converging evidence in this area and highlights key questions that remain...
  6. ncbi request reprint The diagnosis of mental disorders: the problem of reification
    Steven E Hyman
    Department of Neurobiology, Harvard Medical School, Harvard University, Cambridge, Massachusetts 02138, USA
    Annu Rev Clin Psychol 6:155-79. 2010
    ..Insights that are beginning to emerge from psychology, neuroscience, and genetics suggest possible strategies for moving forward...
  7. pmc How might cocaine interfere with brain development?
    Steven E Hyman
    Harvard University, Cambridge, Massachusetts, United States of America
    PLoS Med 5:e130. 2008
  8. ncbi request reprint Neural mechanisms of addiction: the role of reward-related learning and memory
    Steven E Hyman
    Office of the Provost, Harvard University, Cambridge, Massachusetts 02138, USA
    Annu Rev Neurosci 29:565-98. 2006
    ..Here we review progress in identifying candidate mechanisms of addiction...
  9. doi request reprint Cognitive enhancement: promises and perils
    Steven E Hyman
    Office of the Provost, Massachusetts Hall, Harvard University, Cambridge, MA 02138, USA
    Neuron 69:595-8. 2011
    ..Here, I provide a context for discussions based on medical, regulatory, and ethical concerns that have been raised by the possibility that enhancers will emerge from current efforts to discover drugs for neuropsychiatric disorders...
  10. ncbi request reprint Can neuroscience be integrated into the DSM-V?
    Steven E Hyman
    Harvard University, Massachusetts Hall, Cambridge, Massachusetts 02138, USA
    Nat Rev Neurosci 8:725-32. 2007
    ..It is thus timely to ask whether neuroscience has progressed to the point that the next editions of these manuals can usefully incorporate information about brain structure and function...
  11. ncbi request reprint The neurobiology of addiction: implications for voluntary control of behavior
    Steven E Hyman
    Harvard University, Cambridge, MA 02138, USA
    Am J Bioeth 7:8-11. 2007
    ..Possible mechanisms and implications are briefly reviewed...
  12. ncbi request reprint How mice cope with stressful social situations
    Steven E Hyman
    Department of Neurobiology, Harvard Medical School, Massachusetts Hall, Cambridge, MA 02138, USA
    Cell 131:232-4. 2007
    ..As a step toward understanding the neural basis for these individual differences, Krishnan et al. (2007) reveal molecular changes in the brain's reward circuits that make some mice resistant to the effects of social defeat...
  13. ncbi request reprint Medicine. What are the right targets for psychopharmacology?
    Steven E Hyman
    Harvard University, Boston, MA 02138, USA
    Science 299:350-1. 2003
  14. doi request reprint Progress in the genetics of polygenic brain disorders: significant new challenges for neurobiology
    Steven A McCarroll
    Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA 02141, USA Department of Genetics, Harvard Medical School, Boston, MA 02115, USA Electronic address
    Neuron 80:578-87. 2013
    ..We argue that technologies at the disposal of neuroscience are adequately advanced to begin to study the biology of common and devastating polygenic disorders. ..
  15. doi request reprint A glimmer of light for neuropsychiatric disorders
    Steven E Hyman
    Office of the Provost, Harvard University, Department of Neurobiology, Harvard Medical School, Massachusetts Hall, Cambridge, Massachusetts 02138, USA
    Nature 455:890-3. 2008
    ..Now, modern genomic technologies have begun to facilitate the discovery of relevant genes...
  16. ncbi request reprint Neuroscience, genetics, and the future of psychiatric diagnosis
    Steven E Hyman
    Harvard University, Cambridge, MA 02138, USA
    Psychopathology 35:139-44. 2002
    ....
  17. ncbi request reprint Decreased absolute amygdala volume in cocaine addicts
    Nikos Makris
    Motivation and Emotion Neuroscience Collaboration, Department of Radiology, Harvard Medical School, Boston, MA 02129, USA
    Neuron 44:729-40. 2004
    ..These findings argue for a condition that predisposes the individual to cocaine dependence by affecting the amygdala, or a primary event early in the course of cocaine use...
  18. doi request reprint Cognition in schizophrenia
    Steven E Hyman
    Am J Psychiatry 165:312. 2008
  19. ncbi request reprint Computational roles for dopamine in behavioural control
    P Read Montague
    Department of Neuroscience, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, USA
    Nature 431:760-7. 2004
    ..The application of such quantitative models has opened up new fields, ripe for attack by young synthesizers and theoreticians...
  20. ncbi request reprint Levels of analysis in psychiatric research
    Kathy L Kopnisky
    NIH, National Institute of Mental Health, Bethesda, MD 20892 9619, USA
    Dev Psychopathol 14:437-61. 2002
    ..This article reviews how these different levels contribute to our understanding of a number of psychiatric disorders, including drug addiction, which has been the focus of much of our own work...
  21. ncbi request reprint Can autism speak to neuroscience?
    Steven O Moldin
    Department of Psychiatry and Office of the Vice Provost for Research Advancement, University of Southern California, Los Angeles, California 90089, USA
    J Neurosci 26:6893-6. 2006
  22. ncbi request reprint The human genome project and its impact on psychiatry
    W Maxwell Cowan
    National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Annu Rev Neurosci 25:1-50. 2002
    ....
  23. ncbi request reprint Recruiting and retaining future generations of physician scientists in mental health
    David J Kupfer
    Department of Psychiatry, University of Pittsburgh Medical Center, PA, USA
    Arch Gen Psychiatry 59:657-60. 2002
    ..A coalition of stakeholders--federal, academic, foundational, and in the pharmaceutical industry--is needed to meet these challenges...
  24. ncbi request reprint Regulation of ania-6 splice variants by distinct signaling pathways in striatal neurons
    Véronique Sgambato
    Molecular Plasticity Section, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA
    J Neurochem 86:153-64. 2003
    ..These data suggest that different neuronal signals can differentially regulate splicing and that different intracellular pathways can be recruited to yield a given splice variant...
  25. ncbi request reprint Diagnosing disorders
    Steven E Hyman
    Harvard Medical School
    Sci Am 289:96-103. 2003
  26. ncbi request reprint Methylphenidate-induced plasticity: what should we be looking for?
    Steven E Hyman
    Biol Psychiatry 54:1310-1. 2003
  27. ncbi request reprint Metabotropic glutamate receptors and dopamine receptors cooperate to enhance extracellular signal-regulated kinase phosphorylation in striatal neurons
    Pamela J Voulalas
    Molecular Plasticity Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 25:3763-73. 2005
    ..Thus, signal transduction pathways activated by DR1/5 and mGluR5 interact to modify downstream events in striatal neurons while retaining numerous regulatory checkpoints...
  28. ncbi request reprint Introduction: the brain's special status
    Steven E Hyman
    Cerebrum 6:9-12. 2004
  29. ncbi request reprint Even chromatin gets the blues
    Steven E Hyman
    Nat Neurosci 9:465-6. 2006
  30. ncbi request reprint Managing emotional fallout. Parting remarks from America's top psychiatrist. Interview by Diane Coutu
    Steven E Hyman
    Harv Bus Rev 80:55-60, 127. 2002
    ..And he suggests that September 11, 2001, may come to be seen as a tipping point--the moment when managers started to think about dealing with mental health issues on a regular basis...