Willem Huijbers

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc The encoding/retrieval flip: interactions between memory performance and memory stage and relationship to intrinsic cortical networks
    Willem Huijbers
    Harvard Medical School
    J Cogn Neurosci 25:1163-79. 2013
  2. pmc Explaining the encoding/retrieval flip: memory-related deactivations and activations in the posteromedial cortex
    W Huijbers
    Harvard Medical School, Martinos Center for Biomedical Imaging, Brigham and Women s Hospital, Boston, MA, USA
    Neuropsychologia 50:3764-74. 2012
  3. doi request reprint Imagery and retrieval of auditory and visual information: neural correlates of successful and unsuccessful performance
    Willem Huijbers
    University of Amsterdam, Swammerdam Institute for Life Sciences, Faculty of Science, Amsterdam, The Netherlands
    Neuropsychologia 49:1730-40. 2011
  4. doi request reprint Modality-specific and modality-independent components of the human imagery system
    Sander M Daselaar
    University of Amsterdam, Swammerdam Institute for Life Sciences, Faculty of Science, The Netherlands
    Neuroimage 52:677-85. 2010
  5. pmc Amyloid deposition is linked to aberrant entorhinal activity among cognitively normal older adults
    Willem Huijbers
    Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts 02129, Harvard Aging Brain Study, Department of Neurology, and Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114
    J Neurosci 34:5200-10. 2014
  6. pmc Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease
    Elizabeth C Mormino
    From the Departments of Neurology E C M, A P S, D M R, K A J, R A S, Radiology T H, A P S, K A J, R A S, and Psychiatry A P S, A W, and the Division of Nuclear Medicine and Molecular Imaging, Department of Radiology K A J, Massachusetts General Hospital, Harvard Medical School the Department of Biostatistics R A B, Harvard School of Public Health, Boston the Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology T H, Massachusetts General Hospital, Charleston and the Center for Alzheimer Research and Treatment, Department of Neurology A W, w h, D M R, K A J, R A S, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    Neurology 82:1760-7. 2014
  7. pmc The ups and downs of the posteromedial cortex: age- and amyloid-related functional alterations of the encoding/retrieval flip in cognitively normal older adults
    Patrizia Vannini
    Department of Psychiatry, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Cereb Cortex 23:1317-28. 2013
  8. pmc Template based rotation: a method for functional connectivity analysis with a priori templates
    Aaron P Schultz
    Harvard Aging Brain Study, Massachusetts Alzheimer s Disease Research Center, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129 USA Electronic address
    Neuroimage 102:620-36. 2014
  9. pmc Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression
    Willem Huijbers
    1 Centre for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA 2 Athinoula A Martinos Centre for Biomedical Imaging, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
    Brain 138:1023-35. 2015
  10. pmc Relationships between default-mode network connectivity, medial temporal lobe structure, and age-related memory deficits
    Andrew M Ward
    Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA, USA
    Neurobiol Aging 36:265-72. 2015

Detail Information

Publications14

  1. pmc The encoding/retrieval flip: interactions between memory performance and memory stage and relationship to intrinsic cortical networks
    Willem Huijbers
    Harvard Medical School
    J Cogn Neurosci 25:1163-79. 2013
    ..Furthermore, regions within the default network display functional dissociations, and this may have implications for the neural underpinnings of age-related memory disorders...
  2. pmc Explaining the encoding/retrieval flip: memory-related deactivations and activations in the posteromedial cortex
    W Huijbers
    Harvard Medical School, Martinos Center for Biomedical Imaging, Brigham and Women s Hospital, Boston, MA, USA
    Neuropsychologia 50:3764-74. 2012
    ..We will conclude with a summary of the findings and provide directions for future research...
  3. doi request reprint Imagery and retrieval of auditory and visual information: neural correlates of successful and unsuccessful performance
    Willem Huijbers
    University of Amsterdam, Swammerdam Institute for Life Sciences, Faculty of Science, Amsterdam, The Netherlands
    Neuropsychologia 49:1730-40. 2011
    ..This is the first study to separate the neural correlates of successful and unsuccessful performance for both imagery and retrieval and for both auditory and visual modalities...
  4. doi request reprint Modality-specific and modality-independent components of the human imagery system
    Sander M Daselaar
    University of Amsterdam, Swammerdam Institute for Life Sciences, Faculty of Science, The Netherlands
    Neuroimage 52:677-85. 2010
    ..This is the first fMRI study to characterize both modality-specific and modality-independent components of the human imagery system...
  5. pmc Amyloid deposition is linked to aberrant entorhinal activity among cognitively normal older adults
    Willem Huijbers
    Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts 02129, Harvard Aging Brain Study, Department of Neurology, and Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114
    J Neurosci 34:5200-10. 2014
    ..Together these findings link neocortical amyloid-β deposition to neuronal dysfunction specifically in entorhinal cortex, while aging is associated with more widespread functional changes across the MTL. ..
  6. pmc Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease
    Elizabeth C Mormino
    From the Departments of Neurology E C M, A P S, D M R, K A J, R A S, Radiology T H, A P S, K A J, R A S, and Psychiatry A P S, A W, and the Division of Nuclear Medicine and Molecular Imaging, Department of Radiology K A J, Massachusetts General Hospital, Harvard Medical School the Department of Biostatistics R A B, Harvard School of Public Health, Boston the Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology T H, Massachusetts General Hospital, Charleston and the Center for Alzheimer Research and Treatment, Department of Neurology A W, w h, D M R, K A J, R A S, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    Neurology 82:1760-7. 2014
    ..To examine whether β-amyloid (Aβ) and APOE ε4 status independently contribute or interact to influence longitudinal cognitive decline in clinically normal older individuals (CN)...
  7. pmc The ups and downs of the posteromedial cortex: age- and amyloid-related functional alterations of the encoding/retrieval flip in cognitively normal older adults
    Patrizia Vannini
    Department of Psychiatry, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Cereb Cortex 23:1317-28. 2013
    ..These findings support a specific link between amyloid pathology and neural dysfunction in PMC and elucidate the underpinnings of age-related memory dysfunction...
  8. pmc Template based rotation: a method for functional connectivity analysis with a priori templates
    Aaron P Schultz
    Harvard Aging Brain Study, Massachusetts Alzheimer s Disease Research Center, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129 USA Electronic address
    Neuroimage 102:620-36. 2014
    ....
  9. pmc Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression
    Willem Huijbers
    1 Centre for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA 2 Athinoula A Martinos Centre for Biomedical Imaging, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
    Brain 138:1023-35. 2015
    ..Increased hippocampal activity is discussed in relation to neuronal compensation and/or amyloid-β induced excitoxicity...
  10. pmc Relationships between default-mode network connectivity, medial temporal lobe structure, and age-related memory deficits
    Andrew M Ward
    Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA, USA
    Neurobiol Aging 36:265-72. 2015
    ....
  11. pmc The hippocampus is coupled with the default network during memory retrieval but not during memory encoding
    Willem Huijbers
    Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 6:e17463. 2011
    ..Taken together, our findings clarify the relationship between the DMN and the neural correlates of memory retrieval and encoding...
  12. pmc The parahippocampal gyrus links the default-mode cortical network with the medial temporal lobe memory system
    Andrew M Ward
    Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts
    Hum Brain Mapp 35:1061-73. 2014
    ..Our findings support the hypothesis that the MTL memory system represents a functional subnetwork that relates to the cortical nodes of the DMN through parahippocampal functional connections...
  13. pmc Respiration phase-locks to fast stimulus presentations: implications for the interpretation of posterior midline "deactivations"
    Willem Huijbers
    Harvard Medical School, Martinos Center for Biomedical Imaging, Brigham and Women s Hospital, Boston, Massachusetts Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    Hum Brain Mapp 35:4932-43. 2014
    ..Further research is necessary to demonstrate whether our findings are restricted to episodic memory encoding, or also extend to other cognitive domains...
  14. pmc When learning and remembering compete: a functional MRI study
    Willem Huijbers
    Center for Neuroscience, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, The Netherlands
    PLoS Biol 7:e11. 2009
    ..This study not only provides novel insight into our capacity to learn and remember, but also clarifies the neural mechanisms underlying flexible behavior...