Genomes and Genes
Affiliation: Harvard University
- Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without ciliaPeng Huang
Department of Molecular and Cellular Biology, Center for Brain Science, Harvard Stem Cell Institute, Broad Institute, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
Development 136:3089-98. 2009..These results reveal a conserved requirement for cilia in transducing the activity of upstream regulators of Hh signaling but distinct phenotypic effects due to differential regulation and differing roles of transcriptional mediators...
- Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cordPeng Huang
Department of Molecular and Cellular Biology, Center for Brain Science, Harvard Stem Cell Institute, Broad Institute, Center for Systems Biology, Harvard University, Cambridge, Massachusetts, USA
PLoS Genet 8:e1002762. 2012....
- Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limbJunhao Mao
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
Dev Cell 16:600-6. 2009..This study identifies another level of genetic interaction between the orthogonal axes during limb development...